Page last updated: 2024-09-03

4-phenyl-1,2,3,4-tetrahydroisoquinoline and prazosin

4-phenyl-1,2,3,4-tetrahydroisoquinoline has been researched along with prazosin in 2 studies

Compound Research Comparison

Studies
(4-phenyl-1,2,3,4-tetrahydroisoquinoline)
Trials
(4-phenyl-1,2,3,4-tetrahydroisoquinoline)
Recent Studies (post-2010)
(4-phenyl-1,2,3,4-tetrahydroisoquinoline)
Studies
(prazosin)
Trials
(prazosin)
Recent Studies (post-2010) (prazosin)
13037,914713682

Protein Interaction Comparison

ProteinTaxonomy4-phenyl-1,2,3,4-tetrahydroisoquinoline (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuduka, H; Hasebe, Y; Hirobe, M; Nagao, T; Ohta, S; Ono, H; Satoh, M1
Hirobe, M; Nagao, T; Ohta, S; Ono, H; Tateyama, M1

Other Studies

2 other study(ies) available for 4-phenyl-1,2,3,4-tetrahydroisoquinoline and prazosin

ArticleYear
Amphetamine-antagonistic properties of 4-phenyl-1,2,3,4- tetrahydroisoquinoline: inhibition of spinal reflex-enhancing effects of methamphetamine, phenylethylamine and nomifensine.
    Brain research, 1991, Nov-15, Volume: 564, Issue:2

    Topics: Amphetamine; Animals; Blood Pressure; Decerebrate State; Electric Stimulation; Isoquinolines; Male; Methamphetamine; Nomifensine; Phenethylamines; Prazosin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Reflex, Monosynaptic; Spinal Cord; Tetrahydroisoquinolines

1991
Effect of 4-phenyl-1,2,3,4-tetrahydroisoquinoline on ambulation induced by injection of methamphetamine into the nucleus accumbens in rats.
    Neuropharmacology, 1993, Volume: 32, Issue:3

    Topics: Animals; Corpus Striatum; Haloperidol; Injections; Injections, Subcutaneous; Isoquinolines; Male; Methamphetamine; Motor Activity; Nucleus Accumbens; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Membranes; Tetrahydroisoquinolines

1993