4-oxo-enoxacin has been researched along with enoxacin in 8 studies
| Studies (4-oxo-enoxacin) | Trials (4-oxo-enoxacin) | Recent Studies (post-2010) (4-oxo-enoxacin) | Studies (enoxacin) | Trials (enoxacin) | Recent Studies (post-2010) (enoxacin) |
|---|---|---|---|---|---|
| 10 | 2 | 0 | 734 | 74 | 122 |
| Protein | Taxonomy | 4-oxo-enoxacin (IC50) | enoxacin (IC50) |
|---|---|---|---|
| V-type proton ATPase subunit B, brain isoform | Homo sapiens (human) | 10 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 10 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 10 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 10 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 10 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 10 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 10 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 10 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Egawa, H; Matsumoto, J; Minamida, A; Miyamoto, T; Nishimura, H; Nishimura, Y | 1 |
| Apichartpichean, R; Hasegawa, T; Kuzuya, T; Miyamoto, K; Muraoka, I; Nadai, M; Takagi, K | 1 |
| Dudley, MN; George, B; Stolear, JC; Van der Auwera, P | 1 |
| Hasegawa, T; Kuzuya, T; Muraoka, I; Nadai, M; Takagi, K; Yoshizumi, H | 1 |
| Baker, SL; Griggs, D; Misra, M; Wise, R | 1 |
| Jaehde, U; Naber, KG; Schunack, W; Sörgel, F; Zürcher, J | 1 |
| Audran, M; Bressolle, F; Costa, P; Hamel, B | 1 |
| Audran, M; Bressolle, F; Costa, P; Hamel, B; Mottet, N | 1 |
2 trial(s) available for 4-oxo-enoxacin and enoxacin
| Article | Year |
|---|---|
Distribution kinetics of enoxacin and its metabolite oxoenoxacin in excretory fluids of healthy volunteers.
Topics: Adult; Chromatography, High Pressure Liquid; Enoxacin; Humans; Injections, Intravenous; Male; Nasal Mucosa; Saliva; Sweat; Tears | 1995 |
Reversed-phase high-performance liquid chromatographic determination of enoxacin and 4-oxo-enoxacin in human plasma and prostatic tissue. Application to a pharmacokinetic study.
Topics: Adenoma; Anti-Infective Agents; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Enoxacin; Humans; Indicators and Reagents; Male; Prostate; Prostatic Neoplasms; Solvents | 1998 |
6 other study(ies) available for 4-oxo-enoxacin and enoxacin
| Article | Year |
|---|---|
Pyridonecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1,6,7-trisubstituted 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Enoxacin; Escherichia coli; Mice; Naphthyridines; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship | 1984 |
The possible mechanism of interaction between xanthines and quinolone.
Topics: Animals; Anti-Infective Agents; Blood Proteins; Bronchodilator Agents; Drug Interactions; Enoxacin; Fluoroquinolones; Male; Quinolones; Rats; Rats, Inbred Strains; Xanthines | 1990 |
Pharmacokinetics of enoxacin and its oxometabolite following intravenous administration to patients with different degrees of renal impairment.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Enoxacin; Half-Life; Humans; Injections, Intravenous; Kidney Failure, Chronic; Middle Aged; Renal Dialysis | 1990 |
Effects of enoxacin on renal and metabolic clearance of theophylline in rats.
Topics: Animals; Enoxacin; Kidney; Male; Rats; Rats, Inbred Strains; Theophylline; Uric Acid | 1990 |
The pharmacokinetics of enoxacin in elderly patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Chromatography, High Pressure Liquid; Enoxacin; Female; Half-Life; Humans; Kinetics; Male; Naphthyridines; Urinary Tract Infections | 1987 |
Diffusion of enoxacin and its oxo-metabolite into human epididymal tissue.
Topics: Aged; Anti-Infective Agents, Urinary; Diffusion; Enoxacin; Epididymis; Humans; Male; Middle Aged; Prostate | 2000 |