Compounds > 4-oxo-2-nonenal
Page last updated: 2024-09-05

4-oxo-2-nonenal and linoleic acid

4-oxo-2-nonenal has been researched along with linoleic acid in 6 studies

Compound Research Comparison

Studies
(4-oxo-2-nonenal)		Trials
(4-oxo-2-nonenal)		Recent Studies (post-2010)
(4-oxo-2-nonenal)		Studies
(linoleic acid)		Trials
(linoleic acid)		Recent Studies (post-2010) (linoleic acid)
940476,8783142,036

Protein Interaction Comparison

ProteinTaxonomy4-oxo-2-nonenal (IC50)linoleic acid (IC50)
Fatty acid-binding protein, heartHomo sapiens (human)1
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1
Fatty acid-binding protein, adipocyteHomo sapiens (human)1
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.69

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, J; Sayre, LM; Xu, G; Yuan, Q; Zhang, WH1
Kawai, Y; Osawa, T; Uchida, K1
Sayre, LM; Zhu, X2
Kuiper, HC; Miranda, CL; Sowell, JD; Stevens, JF1
Fujioka, S; Lee, SH; Oe, T; Takahashi, R1

Other Studies

6 other study(ies) available for 4-oxo-2-nonenal and linoleic acid

ArticleYear
Model studies on protein side chain modification by 4-oxo-2-nonenal.
    Chemical research in toxicology, 2003, Volume: 16, Issue:4

    Topics: Acetylcysteine; Aldehydes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Histidine; Imidazoles; Linoleic Acid; Lysine; Magnetic Resonance Spectroscopy; Oxygen; Proteins; Pyrroles; Ribonucleases; Stereoisomerism; Structure-Activity Relationship

2003
2'-deoxycytidine in free nucleosides and double-stranded DNA as the major target of lipid peroxidation products.
    Free radical biology & medicine, 2004, Mar-01, Volume: 36, Issue:5

    Topics: Aldehydes; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyguanosine; DNA; Free Radicals; Linoleic Acid; Lipid Peroxidation; Mass Spectrometry

2004
Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal.
    Redox report : communications in free radical research, 2007, Volume: 12, Issue:1

    Topics: Aldehydes; Kinetics; Linoleic Acid; Mass Spectrometry; Models, Molecular; Molecular Conformation; Proteins; Schiff Bases

2007
Long-lived 4-oxo-2-enal-derived apparent lysine michael adducts are actually the isomeric 4-ketoamides.
    Chemical research in toxicology, 2007, Volume: 20, Issue:2

    Topics: Aldehydes; Amides; Animals; Borohydrides; Cattle; Lactoglobulins; Linoleic Acid; Lysine; Molecular Structure; Stereoisomerism; Time Factors

2007
Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.
    The Journal of biological chemistry, 2008, Jun-20, Volume: 283, Issue:25

    Topics: Acetylcysteine; Aldehydes; Animals; Biomarkers; Carbon Tetrachloride; Chromatography, Liquid; Lactones; Linoleic Acid; Lipid Peroxidation; Mass Spectrometry; Models, Chemical; Oxidative Stress; Rats; Rats, Inbred F344

2008
Angiotensin II-Induced Oxidative Stress in Human Endothelial Cells: Modification of Cellular Molecules through Lipid Peroxidation.
    Chemical research in toxicology, 2019, 07-15, Volume: 32, Issue:7

    Topics: Aldehydes; Angiotensin II; Ascorbic Acid; Carbon Isotopes; Cell Line; Copper Sulfate; Endothelial Cells; Humans; Isotope Labeling; Linoleic Acid; Lipid Peroxidation; Oxidative Stress; Receptor, Angiotensin, Type 1

2019