4-o-methyl-12-o-tetradecanoylphorbol 13-acetate has been researched along with tetradecanoylphorbol acetate in 153 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (14.38) | 18.7374 |
| 1990's | 8 (5.23) | 18.2507 |
| 2000's | 65 (42.48) | 29.6817 |
| 2010's | 53 (34.64) | 24.3611 |
| 2020's | 5 (3.27) | 2.80 |
| Authors | Studies |
|---|---|
| Ledbetter, ML; Medrek, PL; Spinney, BM | 1 |
| Moens, W; Rolin-Limbosch, S; Szpirer, C | 1 |
| Marian, B | 2 |
| Danner, MW; Marian, B | 1 |
| DiGiovanni, J; Naito, M; Naito, Y | 1 |
| Anderson, D; Dewdney, RS; Soper, CJ | 1 |
| Bayard, F; Darbon, JM; Valette, A | 1 |
| Abernethy, DJ; Boreiko, CJ; Dorman, BH; Sanchez, JH | 1 |
| Baxter, CS; Patskan, GJ | 1 |
| Klein-Szanto, AJ; Major, SK; Slaga, TJ | 1 |
| Peterfreund, RA; Vale, WW | 1 |
| DiCorleto, PE; Fox, PL | 1 |
| Janowsky, A; Labarca, R; Patel, J; Paul, SM | 1 |
| Bojan, F; Fox, M; Kinsella, AR | 1 |
| Carubia, JM; Kirkwood, JM; Macala, LJ; Varga, JM; Yu, RK | 1 |
| Fischer, SM; Gleason, GL; Nelson, K; Slaga, TJ | 1 |
| Goerttler, K; Hecker, E; Hesse, B; Loehrke, H; Schweitzer, J; Seip, H | 1 |
| Kinzel, V; Richards, J; Stöhr, M | 1 |
| Adamo, S; Caporale, C; Cossu, G; Molinaro, M | 1 |
| Bols, NC; Mosser, DD | 1 |
| Blumberg, PM; Dunphy, WG; Lau, CC | 1 |
| Gimenez, C; Krantic, S; Rabourdin-Combe, C | 1 |
| Erusalimsky, JD; Hong, Y; Martin, JF; Vainchenker, W | 1 |
| Bonev, AD; Jaggar, JH; Nelson, MT; Rubart, M | 1 |
| Brenna, JT; Corso, TN; Van Pelt, CK | 1 |
| Holmgren, A; Kumar, S | 1 |
| Dwivedi, C; Zhang, Y | 1 |
| Chang, CH; Chang, TM; Chey, WY | 1 |
| Choe, TB; Hong, SI; Hur, JH; Lee, SH; Park, IC; Park, MJ; Rhee, CH; Yi, DH | 1 |
| Green, M; Mehta, A; Muimo, R; Mwimbi, XK | 1 |
| Bergin, A; Clothier, RH; Johnson, RO; Ruben, LN | 1 |
| Froscio, M; Murray, AW | 1 |
| Botana, LM; de la Rosa, LA; Vieytes, MR; Vilariño, N | 1 |
| Tou, J; Urbizo, C | 1 |
| Nakamura, J; Ogawa, Y; Suda, T; Suga, S; Takeo, T; Wakui, M | 1 |
| Begenisich, T; Melvin, JE; Park, K | 1 |
| Holian, O; Kakpakova, ES; Ktitorova, OV; Shtil, AA | 1 |
| Arenson, MS; Evans, SC | 1 |
| Conquer, JA; Cruz, TF; Jones, SA | 1 |
| Blusztajn, JK; Frohman, MA; Zhao, D | 1 |
| Chao, JT; Gapor, A; Theriault, A | 1 |
| Aragon, B; Brustis, JJ; Cottin, P; Dargelos, E; Ducastaing, A; Dulong, S; Levieux, D; Poussard, S; Touyarot, K | 1 |
| Isenberg, JS; Kamendulis, LM; Klaunig, JE; Lington, AW; Pugh, G; Smith, JH | 1 |
| Denys, A; Hichami, A; Khan, NA | 1 |
| Bauer, R; Dietz, B; Heilmann, J; Jager, H; Lapke, C; Meinel, L; Merkle, HP | 1 |
| Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Leśkiewicz, M; Tetich, M | 2 |
| Jardemark, KE; Liang, X; Ninan, I; Wang, RY | 1 |
| Do, SH; Ham, BM; Zuo, Z | 1 |
| Gao, ZF; Guo, J; Li, LF | 1 |
| Ahluwalia, J; Bevan, S; Nagy, I; Urban, L | 1 |
| Baba, A; Koyama, Y; Matsuda, T; Yoshioka, Y | 1 |
| Nam, KS; Shon, YH | 1 |
| Dwivedi, C; Hora, JJ; Lansky, EP; Maydew, ER | 1 |
| Kankuri, E; Solatunturi, E; Vapaatalo, H | 1 |
| Aller, P; Amrán, D; de Blas, E; Fernández, C; Ramos, AM; Sancho, P | 1 |
| Chao, W; Choi, SY; Kim, SY; Volsky, DJ | 1 |
| Corazza, F; Harfi, I; Hayez, N; Lema-Kisoka, R; Sariban, E; Svoboda, M | 1 |
| Fyhrquist, F; Nyman, T; Saijonmaa, O | 1 |
| Gong, W; Morishima, S; Okada, Y; Sasaki, S; Shimizu, T; Tachibe, T; Tanabe, S; Uchida, S; Xu, H | 1 |
| Jin, Y; Luo, Y; Zheng, J | 1 |
| Brown, AJ; Quinn, CM; Wong, J | 1 |
| Hartelt, N; Ivannikov, MV; Mironov, SL | 1 |
| Chan, SA; Landmesser, LT; Polo-Parada, L; Smith, C | 1 |
| Fortin, GD; Martel, P; Michel, FJ; Trudeau, LE; Yeomans, J | 1 |
| Ao, L; Cao, J; Huang, MH; Liu, JY; Wu, YZ; Yang, MS; Zeng, ZX; Zhang, YQ | 1 |
| Hayashi, K; Ikeda, K; Inoue, S; Kuno, S; Ohta, K; Ohta, M; Toyomoto, M | 1 |
| Han, P; Lucero, MT | 1 |
| Calixto, JB; Ferreira, J; Medeiros, R; Trichês, KM | 1 |
| Guo, Q; Xu, Y; Zhang, Z | 1 |
| Barnes-Davies, M; Bhattacharjee, A; Forsythe, ID; Hamann, M; Kaczmarek, LK; Oliver, DL; Song, P; Yang, Y | 1 |
| Calabrese, B; Halpain, S | 1 |
| Ciubotaru, I; Potempa, LA; Wander, RC | 1 |
| Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K | 1 |
| Chen, Z; Hicks, J; Honeycutt, KA; Koster, MI; Miers, M; Nuchtern, J; Roop, DR; Shohet, JM | 1 |
| Bando, Y; Hashimoto, Y; Iizuka, H; Ishida-Yamamoto, A; Jiang, YP; Kishibe, M; Mitrovic, B; Namikawa, K; Perez, D; Takahashi, H; Terayama, R; Yoshida, S | 1 |
| Ish-Shalom, M; Liron, T; Neumann, D; Seraya, CB; Souroujon, MC | 1 |
| Mao, LM; Tang, Q; Wang, JQ | 1 |
| Acosta, E; Castro, E; Cruzblanca, H; Mendoza, V | 1 |
| Fischer, MJ; Reeh, PW | 1 |
| Gillis, KD; Liu, X; Shu, Y; Takahashi, M; Yang, Y | 1 |
| Armsen, W; Bassan, M; Brasch, MA; Chen, W; Desilva, T; Gether, U; Irwin, N; Liu, H; Madsen, KL; Paradise, A; Rosenberg, PA; Staudinger, J; Zhou, J | 1 |
| Arakawa, Y; Tomimatsu, N | 1 |
| Rola, R; Szulczyk, B; Szulczyk, P; Witkowski, G | 1 |
| Castillo-Alemán, R; Gutiérrez-Venegas, G | 1 |
| Ebensperger, RA; Edwards, AM; Foncea, RE; Galarce, GD; Pessoa-Mahana, CD; Pessoa-Mahana, H | 1 |
| Berger, ML; Pifl, C; Rebernik, P; Reither, H; Wolf, A | 1 |
| Lewis, DA; Manier, DH; Sanders-Bush, E; Shelton, RC | 1 |
| Kim, H; Lee, S; Lee, WH; Mori, K; Park, HC; Park, JY; Suk, K | 1 |
| May, JM; Qiao, H | 1 |
| Han, S; Meier, KE | 1 |
| Baker, O; Camden, J; Erb, L; Kong, Q; Peterson, TS; Seye, CI; Simonyi, A; Stanley, E; Sun, GY; Weisman, GA; Wood, WG | 1 |
| Fraser, JF; Fung, YL; Tung, JP; Wood, P | 1 |
| Gugger, OS; Kapfhammer, JP | 1 |
| Geiger, JE; Groten, CJ; Hung, AY; Magoski, NS; Tam, AK | 1 |
| Evers, DM; Herrick, S; Lee, JY; Pak, DT; Udagawa, N | 1 |
| Bartos, JA; Beazely, MA; Chen, Y; Hell, JW; Li, H; Macdonald, JF; Ulrich, JD | 1 |
| Albani, D; Batelli, S; De Mauro, S; De Ronchi, D; Forloni, G; Kalofoutis, A; Liappas, I; Mailis, A; Malitas, P; Olgiati, P; Piperi, C; Politis, A; Polito, L; Serretti, A; Signorini, A; Stamouli, E; Zisaki, A | 1 |
| Gude, RP; Jain, M; Ratheesh, A | 1 |
| Li, ZQ; Song, L; Yang, P; Yin, YQ | 1 |
| Arnhold, J; Glander, HJ; Lessig, J; Neu, B; Reibetanz, U | 1 |
| Ben, LH; Cravens, PD; Gocke, AR; Hussain, RZ; Liu, Y; Lovett-Racke, AE; McTigue, DM; Peng, H; Puttaparthi, K; Racke, MK; Wei, P; Winger, R; Yang, Y | 1 |
| Ali, AM; Lajis, NH; Mooi, LY; Wahab, NA | 1 |
| Chen, Y; Li, BL; Li, T; Lu, DQ | 1 |
| Chew, EH; Chui, WK; Ling, H; Tan, SH; Yang, H | 1 |
| Hur, S; Kim, TY; Lee, YS; Yang, JH; Yoo, H | 1 |
| Azuma, S; Eshima, K; Kamiya, Y; Kubo, M; Maekawa, T; Nagashima, R; Obata, F; Ohta, E | 1 |
| Andreoli, V; Bocco, JL; De Paul, AL; Gutiérrez, S; Palmeri, CM; Petiti, JP; Sosa, Ldel V; Torres, AI | 1 |
| Acott, P; Beck, PL; Muruve, DA; Seamone, ME; Tibbles, LA; Wang, W | 1 |
| Goodfellow, SJ; Medler, KF; Rebello, MR; Roberts, SG; Rudd, SG; Toska, E; Zeef, LA | 1 |
| Jeong, HJ; Kim, HM; Kim, NH | 1 |
| Abeti, R; Abramov, AY; Duchen, MR | 1 |
| Argetsinger, LS; Carter-Su, C; Lanning, NJ; Su, HW | 1 |
| Chen, YH; Lee, MF; Lin, SJ; Wang, NM; Wu, HJ | 1 |
| Evers, BM; Guo, Z; Wang, Q; Weiss, HL; Zhou, Y | 1 |
| Huang, C; Jiao, Q; Liu, Y; Song, TS; Xu, X; Yang, PB; Zhang, JF; Zhao, LY | 1 |
| Antal, CE; Boitano, AE; Cooke, MP; de Lichtervelde, L; Krastel, P; Newton, AC; Petersen, F; Schultz, PG; Wang, Y | 1 |
| Last, V; Werling, D; Williams, A | 1 |
| Cha, MJ; Chang, W; Choi, E; Choi, EJ; Ham, O; Hong, BK; Hwang, KC; Jang, Y; Kim, IK; Lee, CY; Lee, SY; Lim, S; Park, JH; Song, BW; Song, H | 1 |
| Bae, YC; Kang, Y; Kawakami, S; Saito, M; Sato, H; Toyoda, H | 1 |
| Becker, T; Dietersdorfer, E; Kiener, H; Kloesch, B; Steiner, G | 1 |
| DeCicco-Skinner, KL; Dempsey, TA; Deshpande, MM; Nolan, SJ; Trovato, EL; Wiest, JS | 1 |
| Reetz, O; Strauss, U | 1 |
| Davie, JR; Drobic, B; He, S; Healy, S; Khan, P; Pérez-Cadahía, B | 1 |
| Bera, H; Chui, WK; Dolzhenko, AV; Dutta Gupta, S; Sun, L | 1 |
| Bernhardt, I; Kaestner, L; Wagner-Britz, L; Wang, J | 1 |
| Choi, IS; Go, JH; Han, NR; Han, SJ; Jeong, HJ; Kang, SW; Kim, HM; Kim, JS; Kim, MJ; Kim, YS; Lee, BJ; Moon, PD; Nam, SY; Oh, HA; Yoon, S | 1 |
| Baban, B; Chandler, P; DuHadaway, JB; Keough, MP; Mandik-Nayak, L; Mellor, AL; Merlo, LM; Metz, R; Muller, AJ; Pigott, E; Prendergast, GC; Rust, S; Smith, C | 1 |
| Berkovic, SF; Dibbens, LM; Dlugos, DJ; Gazina, EV; Goldstein, DB; Heron, SE; Li, M; Milligan, CJ; Nair, U; Petrou, S; Petrovski, S; Reid, CA; Scheffer, IE; Trager, C; Venkat, A; Younkin, DP | 1 |
| Jang, EH; Jang, SY; Jeong, SY; Kim, JH; Lee, JK | 1 |
| Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
| Dai, D; Dai, Y; Ding, Z; Mehta, JL; Wang, X | 1 |
| Chen, D; Feng, Z; Li, D; Li, J; Luo, L; Shi, Q; Xia, J; You, Z; Zhao, L; Zuo, G | 1 |
| Chang, X; Huang, D; Li, Q; Liang, B; Liu, G; Liu, Y; Song, X; Su, Z; Sui, X; Zhou, Y | 1 |
| Cho, HJ; Choi, MS; Jung, JI; Jung, YJ; Kang, YH; Park, JH; Sung, MK; Yu, R | 1 |
| Ito, M; Kawachi, M; Kojima, R | 1 |
| Caruso, G; da Silva, JA; de Campos, RP; Fresta, CG; Lunte, SM; Siegel, JM | 1 |
| Liu, F; Weng, SJ; Yang, XL; Zhong, YM | 1 |
| Chen, YJ; Feng, YF; Hu, JG; Jiang, ZS; Lü, HZ; Shi, LL; Xi, J; Xie, XM; Zhang, C; Zhang, N; Zhu, AY | 1 |
| Abrial, E; Delcourte, S; El Mansari, M; Haddjeri, N; Lau, T; Matthaeus, F; Mnie-Filali, O; Pershon, A; Sánchez, C; Schloss, P | 1 |
| Ishizaki, M; Isobe, T; Sano, S; Shimozato, T; Suzuki, K; Takaishi, M | 1 |
| Aoki, M; Furue, Y; Fusamae, Y; Imura, C; Okuda, T; Oshima, I; Shichijo, M; Suzuki, M; Tsujii, K; Ueyama, A; Yamamoto, M; Yasui, K | 1 |
| Hancock, REW; Lee, AH; Wu, BC | 1 |
| Cao, YJ; Du, WX; Huang, YB; Liu, CF; Liu, HH; Shi, LY; Sun, JJ; Wang, F; Yin, XW; Zhang, YL | 1 |
| Chen, Q; Jiang, L; Jin, Q; Li, X; Sun, X; Wei, L; Xu, Y; Zhao, Z | 1 |
| Amatori, S; Errico Provenzano, A; Fanelli, M; Gambarara, A; Mastrogiacomo, AR; Nasoni, MG; Persico, G; Russo, S | 1 |
| Collado-Diaz, V; Friess, MC; Hagedorn, O; Haghayegh Jahromi, N; Halin, C; Jadhav, M; Leroux, JC; Polomska, A; Proulx, ST; Vallone, A; Vranova, M; Willrodt, AH | 1 |
| Ding, ZD; Fu, YJ; Jiang, YJ; Shang, H; Song, CB; Xu, JJ; Zhang, ZN; Zheng, JF | 1 |
| Lord, GM; Omer, OS; Powell, N | 1 |
| Ahn, KS; Han, HK; Harmalkar, DS; Hwang, D; Jeong, HG; Kim, JH; Kwon, OK; Lee, JW; Lee, K; Min, JH; Oh, SR; Park, JW; Song, JG; Xuezhen, X | 1 |
| Al-Sharea, A; Choi, JSY; de Haan, JB; Jandeleit-Dahm, K; Mukhamedova, N; Murphy, AJ; Ritchie, RH; Sharma, A; Simpson, DS; Stefanovic, N; Sviridov, D; Vince, JE | 1 |
| De Poi, RP; El Kholy, K; Kowolik, M; Oshida, Y | 1 |
1 trial(s) available for 4-o-methyl-12-o-tetradecanoylphorbol 13-acetate and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Role of activator protein-1 in the transcription of interleukin-5 gene regulated by protein kinase C signal in asthmatic human T lymphocytes.
Topics: Adult; Asthma; Female; Humans; Interleukin-5; Male; Protein Kinase C; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2005 |
152 other study(ies) available for 4-o-methyl-12-o-tetradecanoylphorbol 13-acetate and tetradecanoylphorbol acetate
| Article | Year |
|---|---|
Potassium transfer assay for cell communication: effects of phorbol esters, retinoic acid, and furosemide.
Topics: 3T3 Cells; Animals; Biological Transport; Cell Communication; Cells, Cultured; Furosemide; Humans; Infant, Newborn; Mice; Ouabain; Potassium; Rubidium; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Effects of tumour promoters on metabolic cooperation between human hepatoma cells.
Topics: Carcinogens; Carcinoma, Hepatocellular; Cell Communication; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Liver Neoplasms; Phenobarbital; Tetradecanoylphorbol Acetate | 1986 |
Enhancement of collagen-degrading enzymes in the dermis after one topical application of tumor-promoting phorbol esters.
Topics: Administration, Topical; Animals; Calcimycin; Collagen; Epidermis; Female; Mice; Phorbol Esters; Tetradecanoylphorbol Acetate | 1986 |
Skin tumor promotion is associated with increased type V collagen content in the dermis.
Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Collagen; Epidermis; Female; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Tumor-promoting phorbol esters cause a stable reduction of dermal collagen in mouse skin.
Topics: Animals; Calcimycin; Cell Division; Collagen; Female; Fluocinolone Acetonide; Mice; Phorbol Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents.
Topics: Animals; Anthracenes; Benzo(a)pyrene; Carcinogens; Diterpenes; Lyngbya Toxins; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Skin; Skin Neoplasms; Species Specificity; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Characterization of lymphocyte stimulation by phorbol related compounds.
Topics: Adolescent; Adult; Animals; Humans; Irritants; Lymphocyte Activation; Male; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phytohemagglutinins; Skin Tests; Tetradecanoylphorbol Acetate | 1988 |
Phorbol esters inhibit the proliferation of MCF-7 cells. Possible implication of protein kinase C.
Topics: Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Effect of mouse skin tumor promoters upon [3H]uridine exchange and focus formation in cultures of C3H/10T1/2 mouse fibroblasts.
Topics: Animals; Carcinogens; Cells, Cultured; Dimethyl Sulfoxide; Diterpenes; Female; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Polychlorinated Dibenzodioxins; Pregnancy; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Uridine | 1986 |
Specific stimulation by phorbol esters of the phosphorylation of histones H2B and H4 in murine lymphocytes.
Topics: Animals; Cells, Cultured; Histones; Lymphocytes; Mice; Mice, Inbred BALB C; Phorbol Esters; Phorbols; Phosphorylation; Tetradecanoylphorbol Acetate | 1985 |
Quantitative evaluation of dark keratinocytes induced by several promoting and hyperplasiogenic agents: their use as an early morphological indicator of tumor-promoting action.
Topics: Alkynes; Anthralin; Calcimycin; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Hyperplasia; Keratins; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Phorbol diesters stimulate somatostatin secretion from cultured brain cells.
Topics: Alkaloids; Animals; Cell Line; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Hypothalamus; Lyngbya Toxins; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate; Verapamil | 1983 |
Regulation of production of a platelet-derived growth factor-like protein by cultured bovine aortic endothelial cells.
Topics: Animals; Aorta; Cattle; Cell Division; Cells, Cultured; DNA Replication; Endothelium; Hydrogen-Ion Concentration; Iodine Radioisotopes; Kinetics; Platelet-Derived Growth Factor; Protein Biosynthesis; Tetradecanoylphorbol Acetate | 1984 |
Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices.
Topics: Animals; Caenorhabditis elegans Proteins; Carbachol; Carcinogens; Carrier Proteins; Hippocampus; Inositol; Inositol Phosphates; Male; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1984 |
Effect of tumor promoter 12-O-tetradecanoylphorbol-13-acetate on recovery of methotrexate-, N-(phosphonacetyl)-L-aspartate-, and cadmium-resistant colony-forming mouse and hamster cells.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cadmium; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Kinetics; Lung; Methotrexate; Mice; Organophosphorus Compounds; Phorbols; Phosphonoacetic Acid; Tetradecanoylphorbol Acetate | 1983 |
Gangliosides of normal and neoplastic human melanocytes.
Topics: Cell Line; G(M3) Ganglioside; Gangliosides; Humans; Male; Melanocytes; Melanoma; Tetradecanoylphorbol Acetate | 1984 |
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1980 |
Effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and its nonpromoting analogue 4-O-methyl-TPA on dorsal dermal melanocytes of the Syrian golden hamster (Mesocricetus auratus).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Early changes in the cell cycle traverse of HeLa cells induced by tumor promoter TPA resemble irradiation effects.
Topics: DNA; HeLa Cells; Humans; Interphase; Kinetics; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Glycopeptide alterations induced by 12-O-tetradecanoyl phorbol-13-acetate in chick embryo cultured myotubes.
Topics: Animals; Cells, Cultured; Chick Embryo; Chromatography, Affinity; Glycopeptides; Muscles; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
The effect of phorbols on metabolic cooperation between human fibroblasts.
Topics: Autoradiography; Cell Communication; Cell Line; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Mutation; Phorbols; Tetradecanoylphorbol Acetate; Tritium | 1982 |
Phorbol related esters have similar structure-activity relations in Swiss 3T3 cells and chicken embryo fibroblasts.
Topics: Animals; Cells, Cultured; Chick Embryo; Deoxyglucose; Diterpenes; Fibroblasts; Mice; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Cell-to-cell contact via measles virus haemagglutinin-CD46 interaction triggers CD46 downregulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies, Viral; Antigens, CD; Bucladesine; Cell Communication; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Hemagglutinins, Viral; Humans; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Mice; Phosphodiesterase Inhibitors; Protein Kinase C; Receptors, Virus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Inhibition of protein kinase C suppresses megakaryocytic differentiation and stimulates erythroid differentiation in HEL cells.
Topics: Aphidicolin; Biomarkers; Blood Proteins; Cell Cycle; Cell Differentiation; Enzyme Inhibitors; Erythroid Precursor Cells; Gene Expression Regulation, Leukemic; Globins; Glycophorins; Hematopoietic Stem Cells; Hemin; Humans; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Megakaryocytes; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Activators of protein kinase C decrease Ca2+ spark frequency in smooth muscle cells from cerebral arteries.
Topics: Animals; Basilar Artery; Calcium; Calcium Channels; Diglycerides; Enzyme Activation; In Vitro Techniques; Kinetics; Models, Biological; Muscle, Smooth, Vascular; Protein Kinases; Rats; Ryanodine; Tetradecanoylphorbol Acetate | 1997 |
Gas chromatograph injection liner for continuous analyte admission into a mass spectrometer.
Topics: Flow Injection Analysis; Gas Chromatography-Mass Spectrometry; Software; Temperature; Tetradecanoylphorbol Acetate; Vitamin E | 1998 |
Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcimycin; Calcium; Carcinogens; Cocarcinogenesis; Diglycerides; Diterpenes; Enzyme Activation; Enzyme Induction; Epidermis; Female; Fluocinolone Acetonide; Gene Expression Regulation; Glutaredoxins; Glutathione; Ionophores; Mice; Oxidation-Reduction; Oxidoreductases; Phorbol Esters; Protein Kinase C; Proteins; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thioredoxins; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1999 |
Sandalwood oil prevent skin tumour development in CD1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Chemoprevention; Chi-Square Distribution; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Plant Oils; Reference Values; Sesquiterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Cellular mechanism of sodium oleate-stimulated secretion of cholecystokinin and secretin.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Fractionation; Cells, Cultured; Chelating Agents; Cholecystokinin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Duodenum; Egtazic Acid; Enzyme Inhibitors; Intestinal Mucosa; Isoquinolines; Oleic Acid; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Secretin; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells.
Topics: Brain Neoplasms; Glioblastoma; Humans; Matrix Metalloproteinases; Neoplasm Invasiveness; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 2000 |
Protein kinase C regulates the flow rate-dependent decline in human nasal ciliary beat frequency in vitro.
Topics: Adolescent; Adult; Analysis of Variance; Child; Female; Humans; Male; Middle Aged; Mucociliary Clearance; Nose; Protein Kinase C; Tetradecanoylphorbol Acetate | 2000 |
Apoptosis and the cell cycle in Xenopus: PMA and MPMA exposure of splenocytes.
Topics: Animals; Apoptosis; Bromodeoxyuridine; Carcinogens; Cell Cycle; Cell Separation; Cell Size; Cells, Cultured; DNA; Flow Cytometry; Lymphocyte Subsets; Lymphocytes; Random Allocation; Spleen; Tetradecanoylphorbol Acetate; Time Factors; Xenopus laevis | 2000 |
Inhibition of epidermal growth factor binding to cultured mouse epidermal cells by tumor promoters.
Topics: Animals; Carcinogens; Depression, Chemical; Epidermal Cells; Epidermal Growth Factor; Epidermis; ErbB Receptors; Mice; Phorbol Esters; Protein Binding; Tetradecanoylphorbol Acetate | 1980 |
HCO(3)(-) ions modify the role of PKC isoforms in the modulation of rat mast cell functions.
Topics: Animals; Bicarbonates; Biological Assay; Buffers; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Degranulation; Cell Separation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Fura-2; Histamine Release; Ionophores; Isoenzymes; Kinetics; Mast Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 2001 |
Resveratrol inhibits the formation of phosphatidic acid and diglyceride in chemotactic peptide- or phorbol ester-stimulated human neutrophils.
Topics: Choline; Chromatography, Thin Layer; Diglycerides; Drug Interactions; Ethanol; Ethanolamine; Glycerophosphates; Glycerophospholipids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Protein kinase C-dependent and -independent inhibition of Ca(2+) influx by phorbol ester in rat pancreatic beta-cells.
Topics: Action Potentials; Animals; Biological Transport; Calcium; Calcium Channels, L-Type; Cells, Cultured; Drug Synergism; Enzyme Activation; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Maleimides; Nifedipine; Pancreas; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Tolbutamide | 2001 |
Protein kinase A activation phosphorylates the rat ClC-2 Cl- channel but does not change activity.
Topics: Adenosine Triphosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Chloride Channels; Chlorides; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Activation; Epithelial Cells; Humans; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Differential effects of the MDR1 (multidrug resistance) gene-activating agents on protein kinase C: evidence for redundancy of mechanisms of acquired MDR in leukemia cells.
Topics: Ceramides; Cytarabine; Drug Resistance, Multiple; Enzyme Activation; Gene Expression Regulation; Genes, MDR; Humans; Leukemia; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2000 |
Activation of protein kinase C increases acetylcholine release from frog motor nerves by a direct action on L-type Ca(2+) channels and apparently not by depolarisation of the terminal.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Enzyme Inhibitors; Motor Neurons; Naphthalenes; Neuromuscular Junction; Nimodipine; Phorbols; Potassium Chloride; Presynaptic Terminals; Protein Kinase C; Rana temporaria; Staurosporine; Synaptic Transmission; Tetradecanoylphorbol Acetate | 2001 |
Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes.
Topics: Animals; Cattle; Chondrocytes; Dinoprostone; Down-Regulation; Interleukin-1; Lipopolysaccharides; Phospholipase D; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Generation of choline for acetylcholine synthesis by phospholipase D isoforms.
Topics: Acetylcholine; Animals; Cell Line; Choline; Enzyme Activation; Gene Expression; Intracellular Fluid; Isoenzymes; Mice; Molecular Sequence Data; Neurons; Phospholipase D; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Tocotrienol is the most effective vitamin E for reducing endothelial expression of adhesion molecules and adhesion to monocytes.
Topics: Antioxidants; Cell Survival; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; NF-kappa B; Protein Prenylation; Tetradecanoylphorbol Acetate; Tocotrienols; Tumor Necrosis Factor-alpha; Vitamin E | 2002 |
Protein kinase Calpha is a calpain target in cultured embryonic muscle cells.
Topics: Animals; Calpain; Cell Differentiation; Cells, Cultured; Cytoskeletal Proteins; Gene Expression Regulation, Enzymologic; Isoenzymes; Membrane Proteins; Muscle Development; Muscle, Skeletal; Protein Kinase C; Protein Kinase C-alpha; Rats; Rats, Wistar; Substrate Specificity; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Comparative effects of phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and primate hepatocytes.
Topics: Adult; Animals; Cell Communication; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Esters; Female; Gap Junctions; Hepatocytes; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Peroxisome Proliferators; Peroxisomes; Phenobarbital; Phthalic Acids; Pyrimidines; Rats; Rats, Inbred F344; Species Specificity; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2002 |
Eicosapentaenoic acid and docosahexaenoic acid modulate MAP kinase enzyme activity in human T-cells.
Topics: Antibodies; CD3 Complex; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enzyme Activation; Fatty Acids, Unsaturated; Humans; Jurkat Cells; Mitogen-Activated Protein Kinases; Okadaic Acid; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2002 |
Transport of alkamides from Echinacea species through Caco-2 monolayers.
Topics: Biological Transport; Caco-2 Cells; Echinacea; Fatty Acids, Unsaturated; Humans; Lipopolysaccharides; Polyunsaturated Alkamides; Tetradecanoylphorbol Acetate | 2002 |
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases | 2002 |
Protein kinase C is involved in clozapine's facilitation of N-methyl-D-aspartate- and electrically evoked responses in pyramidal cells of the medial prefrontal cortex.
Topics: Alkaloids; Animals; Benzophenanthridines; Clozapine; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Activators; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Fluorobenzenes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Peptide Fragments; Phenanthridines; Phorbols; Piperidines; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Effects of propofol on the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes: the role of protein kinase C.
Topics: Amino Acid Transport System X-AG; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Extracellular Space; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Membrane Potentials; Oocytes; Propofol; Protein Kinase C; Rats; Symporters; Tetradecanoylphorbol Acetate; Xenopus | 2003 |
Overexpression of skin protein kinase C-alpha in anagen hair follicles during induced growth of mouse hair.
Topics: Administration, Topical; Animals; Dermatitis, Contact; Female; Hair; Hair Follicle; Hair Removal; Irritants; Mice; Mice, Inbred C57BL; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate | 2003 |
Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Cannabinoids; Capsaicin; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Ganglia, Spinal; In Vitro Techniques; Male; Nerve Growth Factor; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2003 |
Focal adhesion kinase is required for endothelin-induced cell cycle progression of cultured astrocytes.
Topics: Actins; Amphetamine; Amphetamines; Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; Endothelins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genetic Vectors; Mutation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Inhibition of polyamine biosynthesis in Acanthamoeba castellanii and 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by chitosanoligosaccharide.
Topics: Acanthamoeba; Animals; Cell Division; Cell Line; Cells, Cultured; Chitin; Chitosan; Dose-Response Relationship, Drug; Enzyme Activation; Epidermis; Mice; Oligosaccharides; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Reproducibility of Results; Sensitivity and Specificity; Spermidine; Tetradecanoylphorbol Acetate | 2003 |
Chemopreventive effects of pomegranate seed oil on skin tumor development in CD1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Female; Lythraceae; Mice; Mice, Inbred Strains; Plant Oils; Random Allocation; Seeds; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro.
Topics: Cells, Cultured; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isoenzymes; Leukocytes, Mononuclear; Membrane Proteins; Phenacetin; Phenetidine; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2003 |
12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cadmium Chloride; Caspase 3; Caspases; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; Immunoblotting; Mitogen-Activated Protein Kinases; Monocytes; Oxides; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells | 2004 |
Transcriptional regulation of human excitatory amino acid transporter 1 (EAAT1): cloning of the EAAT1 promoter and characterization of its basal and inducible activity in human astrocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Base Sequence; Blotting, Northern; Cells, Cultured; Cloning, Molecular; Cyclic CMP; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Epidermal Growth Factor; Excitatory Amino Acid Transporter 1; Fetus; Gene Expression Regulation; Glutamic Acid; Humans; Luciferases; Mice; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Rats; Regulatory Sequences, Nucleic Acid; RNA; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcription Initiation Site; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor alpha; Upstream Stimulatory Factors | 2003 |
Regulation of the human corticotropin-releasing-hormone gene promoter activity by antidepressant drugs in Neuro-2A and AtT-20 cells.
Topics: Animals; Antidepressive Agents; Cell Differentiation; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glucocorticoids; Humans; Mice; Molecular Biology; Neuroblastoma; Pituitary Gland; Potassium Chloride; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection | 2004 |
The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) modulate several biochemical pathways in human leukemic myeloid cells.
Topics: Adenosine Triphosphate; Bromodeoxyuridine; Calcium; Cell Line, Tumor; Cyclic AMP; Cytarabine; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Flow Cytometry; Glycophorins; Humans; Immunosuppressive Agents; Inositol Phosphates; Intercellular Adhesion Molecule-1; Leukemia; Myeloid Cells; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Binding; Proto-Oncogene Proteins; Pyrrolidinones; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Transcription Factor AP-1; Vasoactive Intestinal Peptide | 2004 |
Carvedilol inhibits basal and stimulated ACE production in human endothelial cells.
Topics: Carbazoles; Cardiovascular Agents; Carvedilol; Cells, Cultured; Endothelium, Vascular; Humans; Immunoblotting; Peptidyl-Dipeptidase A; Phosphorylation; Propanolamines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Umbilical Veins; Vascular Endothelial Growth Factor A; Vasodilator Agents | 2004 |
ClC-3-independent, PKC-dependent activity of volume-sensitive Cl channel in mouse ventricular cardiomyocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cell Membrane; Cells, Cultured; Chloride Channels; Electric Conductivity; Gene Expression; Heart Ventricles; Isotonic Solutions; Mice; Mice, Mutant Strains; Myocytes, Cardiac; Patch-Clamp Techniques; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 2004 |
[Expression of nerve growth factor mRNA and nerve regeneration after discontinuous injection of phorbol-12-myristate-13-acetate into silicone chamber].
Topics: Animals; Enzyme Activators; Male; Nerve Growth Factor; Nerve Regeneration; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sciatic Nerve; Silicones; Tetradecanoylphorbol Acetate | 2004 |
Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux.
Topics: ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cell Differentiation; Cell Line; Cholesterol; DNA-Binding Proteins; Gene Expression Regulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ligands; Liver X Receptors; Lovastatin; Macrophages; Monocytes; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Tetradecanoylphorbol Acetate | 2004 |
Mitochondrial K(ATP) channels in respiratory neurons and their role in the hypoxic facilitation of rhythmic activity.
Topics: Animals; Animals, Newborn; Calcium; Cell Hypoxia; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Fluorescent Antibody Technique; Fluorescent Dyes; Hydroxy Acids; In Vitro Techniques; Medulla Oblongata; Mice; Mitochondria; Neurons; Periodicity; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Respiration; Staurosporine; Tetradecanoylphorbol Acetate | 2005 |
Adrenal chromaffin cells exhibit impaired granule trafficking in NCAM knockout mice.
Topics: Adrenal Medulla; Animals; Blotting, Western; Calcium; Catecholamines; Chromaffin Cells; Chromaffin Granules; Electric Stimulation; Electrochemistry; Exocytosis; Gene Expression Regulation; Immunohistochemistry; In Vitro Techniques; Membrane Potentials; Membrane Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neural Cell Adhesion Molecules; Qa-SNARE Proteins; Synaptic Vesicles; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2005 |
M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Atropine; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Membrane Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neural Inhibition; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Tetradecanoylphorbol Acetate; Tetrodotoxin; Thapsigargin; Zinc | 2005 |
[Gene expression profiles in early stage of BALB/c 3T3 cells' transformation promoted with 12-O-tetradecanoylphorbol-13-acetate].
Topics: Animals; Apoptosis; BALB 3T3 Cells; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression; Gene Expression Profiling; Methylnitronitrosoguanidine; Mice; Oligonucleotide Array Sequence Analysis; Tetradecanoylphorbol Acetate | 2005 |
Production of NGF, BDNF and GDNF in mouse astrocyte cultures is strongly enhanced by a cerebral vasodilator, ifenprodil.
Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Glial Cell Line-Derived Neurotrophic Factor; Indoles; Maleimides; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nerve Growth Factors; Piperidines; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Pituitary adenylate cyclase activating polypeptide reduces A-type K+ currents and caspase activity in cultured adult mouse olfactory neurons.
Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Analysis of Variance; Animals; Caspases; Cell Count; Cells, Cultured; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Estrenes; Membrane Potentials; Meta-Analysis as Topic; Mice; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Olfactory Mucosa; Olfactory Receptor Neurons; Patch-Clamp Techniques; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium Channel Blockers; Potassium Channels; Propidium; Pyrrolidinones; Tetradecanoylphorbol Acetate | 2005 |
Mechanisms involved in the nociception produced by peripheral protein kinase c activation in mice.
Topics: Adrenergic beta-Antagonists; Analgesics; Animals; Antibodies; Behavior, Animal; Blotting, Western; Bradykinin; Calcitonin Gene-Related Peptide; Capsaicin; Chelating Agents; Dipeptides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Guanethidine; Indoles; Male; Mice; Nociceptors; Pain; Pain Measurement; Peptide Fragments; Propranolol; Protein Kinase C; Ruthenium Red; Salicylates; Sympatholytics; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Acoustic environment determines phosphorylation state of the Kv3.1 potassium channel in auditory neurons.
Topics: Acoustic Stimulation; Action Potentials; Animals; Animals, Newborn; Brain Stem; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Functional Laterality; Gene Expression Regulation; Immunohistochemistry; In Vitro Techniques; Indoles; Maleimides; Neurons; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2005 |
Essential role for the PKC target MARCKS in maintaining dendritic spine morphology.
Topics: Actins; Analysis of Variance; Animals; Cells, Cultured; Dendritic Spines; Diagnostic Imaging; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Fluoroimmunoassay; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Biological; Mutagenesis; Myristoylated Alanine-Rich C Kinase Substrate; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Rats; RNA, Small Interfering; Synapses; Synaptophysin; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2005 |
Production of modified C-reactive protein in U937-derived macrophages.
Topics: Acute-Phase Reaction; Antibodies, Monoclonal; Arteriosclerosis; C-Reactive Protein; Cell Differentiation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Humans; Inflammation; Kinetics; Lipopolysaccharides; Macrophages; Microscopy, Fluorescence; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells | 2005 |
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine | 2006 |
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins.
Topics: Animals; Cell Differentiation; Cell Proliferation; Dermis; Desmoglein 1; Disease Models, Animal; Humans; Kallikreins; Keratinocytes; Mice; Mice, Knockout; Psoriasis; Tetradecanoylphorbol Acetate | 2007 |
Overexpression of amyloid precursor protein reduces epsilon protein kinase C levels.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Line; Chlorocebus aethiops; Cricetinae; Cricetulus; Culture Media, Conditioned; Gene Expression Regulation, Enzymologic; Humans; Mice; Protein Kinase C-epsilon; Protein Transport; Tetradecanoylphorbol Acetate; Transfection | 2007 |
Protein kinase C-regulated cAMP response element-binding protein phosphorylation in cultured rat striatal neurons.
Topics: Animals; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Neurons; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2007 |
Modulation of a delayed-rectifier K+ current by angiotensin II in rat sympathetic neurons.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Delayed Rectifier Potassium Channels; Electric Stimulation; Guanosine Diphosphate; Guanosine Triphosphate; Losartan; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoconstrictor Agents | 2007 |
Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Dinoprostone; Hot Temperature; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxytocics; Receptors, G-Protein-Coupled; Sciatic Nerve; Signal Transduction; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Phosphorylation of SNAP-25 at Ser187 mediates enhancement of exocytosis by a phorbol ester in INS-1 cells.
Topics: Animals; Botulinum Toxins, Type A; Calcium; Cattle; Cells, Cultured; Chromaffin Cells; Dose-Response Relationship, Radiation; Exocytosis; Gene Expression Regulation; Green Fluorescent Proteins; Insulinoma; Membrane Potentials; Mutation; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Rats; Serine; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate; Transfection | 2008 |
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1.
Topics: Alanine; Animals; Biotinylation; Brain; Carrier Proteins; Cells, Cultured; Chlorocebus aethiops; Cytoskeletal Proteins; Embryo, Mammalian; Excitatory Amino Acid Transporter 2; Glutamic Acid; Immunoprecipitation; Mutation; Neurons; Nuclear Proteins; PDZ Domains; Protein Structure, Tertiary; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2008 |
Protein kinase C-mediated protection of motoneurons from excitotoxicity.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Indoles; Maleimides; Motor Neurons; Neuroprotective Agents; Protein Kinase C; Rats; Spinal Cord; Tetradecanoylphorbol Acetate | 2008 |
D(1) dopaminergic control of G protein-dependent inward rectifier K(+) (GIRK)-like channel current in pyramidal neurons of the medial prefrontal cortex.
Topics: Analysis of Variance; Animals; Bee Venoms; Dopamine Agents; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; G Protein-Coupled Inwardly-Rectifying Potassium Channels; In Vitro Techniques; Male; Naphthalenes; Patch-Clamp Techniques; Potassium Channel Blockers; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Dopamine D1; Tetradecanoylphorbol Acetate; Time Factors | 2008 |
Characterization of the transduction pathway involved in c-fos and c-jun expression induced by Aggregatibacter actinomycetemcomitans lipopolysaccharides in human gingival fibroblasts.
Topics: Aggregatibacter actinomycetemcomitans; Cells, Cultured; Fibroblasts; Gingiva; Humans; Lipopolysaccharides; Periodontal Diseases; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Tetradecanoylphorbol Acetate | 2008 |
Biological evaluation of novel 6-Arylbenzimidazo[1,2-c]quinazoline derivatives as inhibitors of LPS-induced TNF-alpha secretion.
Topics: Anti-Inflammatory Agents; HL-60 Cells; Humans; Lipopolysaccharides; Quinazolines; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner.
Topics: Amphetamine; Animals; Binding, Competitive; Cell Line; Chlorides; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Histidine; Humans; Lysine; Male; Membrane Potentials; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Trace Elements; Transfection; Zinc Sulfate | 2009 |
Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A.
Topics: Adult; Age Factors; Aged; Cyclic AMP-Dependent Protein Kinases; Depressive Disorder, Major; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Postmortem Changes; Prefrontal Cortex; Protein Kinase C; Receptor, Serotonin, 5-HT2A; Sex Factors; Tetradecanoylphorbol Acetate; Young Adult | 2009 |
Lipocalin-2 is an autocrine mediator of reactive astrocytosis.
Topics: Amides; Analysis of Variance; Animals; Animals, Newborn; Annexin A2; Apoptosis; Astrocytes; Autocrine Communication; Brain; Cell Movement; Cells, Cultured; Embryo, Nonmammalian; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Inbred ICR; Nitrites; Nitroprusside; Penicillamine; Phagocytes; Propidium; Pyridines; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transfection; Tumor Necrosis Factor-alpha; Zebrafish | 2009 |
Macrophage differentiation increases expression of the ascorbate transporter (SVCT2).
Topics: Cell Differentiation; Cell Line, Tumor; Humans; Macrophages; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; NADPH Oxidases; NF-kappa B; Organic Anion Transporters, Sodium-Dependent; Promoter Regions, Genetic; Protein Kinase C; Sodium-Coupled Vitamin C Transporters; Symporters; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2009 |
Integrated modulation of phorbol ester-induced Raf activation in EL4 lymphoma cells.
Topics: Animals; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Gene Knockdown Techniques; Kinetics; Lymphoma; Mice; Phosphatidylethanolamine Binding Protein; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2009 |
Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Humans; Interleukin-1beta; Neurons; Nucleotides; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Up-Regulation; Uridine Triphosphate | 2009 |
Respiratory burst function of ovine neutrophils.
Topics: Animals; Immunity, Innate; Immunologic Techniques; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Reactive Oxygen Species; Respiratory Burst; Sheep; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Reduced size of the dendritic tree does not protect Purkinje cells from excitotoxic death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calbindins; Cell Death; Cerebellum; Dendrites; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Purkinje Cells; S100 Calcium Binding Protein G; Synapses; Tetradecanoylphorbol Acetate; Vesicular Glutamate Transport Protein 2 | 2010 |
Persistent Ca2+ current contributes to a prolonged depolarization in Aplysia bag cell neurons.
Topics: Animals; Aplysia; Biophysical Phenomena; Biophysics; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Electric Stimulation; Ion Channel Gating; Ions; Membrane Potentials; Neurons; Nickel; Patch-Clamp Techniques; Potassium Channel Blockers; Tetradecanoylphorbol Acetate; Tetraethylammonium | 2009 |
Postsynaptic PDLIM5/Enigma Homolog binds SPAR and causes dendritic spine shrinkage.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Animals; Brain; Carcinogens; Cells, Cultured; Chlorocebus aethiops; COS Cells; Dendritic Spines; Disks Large Homolog 4 Protein; Embryo, Mammalian; Glutamate Decarboxylase; Green Fluorescent Proteins; GTPase-Activating Proteins; Hippocampus; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Confocal; Mutation; Neostigmine; Neurons; Protein Isoforms; Rats; RNA Interference; Synapses; Tetradecanoylphorbol Acetate; Transfection | 2010 |
Postsynaptic clustering and activation of Pyk2 by PSD-95.
Topics: Animals; Animals, Newborn; Antibodies; Brain; Calcium; Calmodulin; Cell Line, Transformed; Disks Large Homolog 4 Protein; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Focal Adhesion Kinase 2; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ionomycin; Ionophores; Male; Membrane Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; PDZ Domains; Phosphorylation; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin; Transfection; Tyrosine | 2010 |
Vitamin B12 levels in Alzheimer's disease: association with clinical features and cytokine production.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoprotein E4; Cytokines; Female; Follow-Up Studies; Humans; Lymphocytes; Male; Mental Status Schedule; Neuropsychological Tests; Radioimmunoassay; Tetradecanoylphorbol Acetate; Up-Regulation; Vitamin B 12 | 2010 |
Pentoxifylline inhibits integrin-mediated adherence of 12(S)-HETE and TNFalpha-activated B16F10 cells to fibronectin and endothelial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Endothelial Cells; Fibronectins; Integrins; Melanoma, Experimental; Mice; Pentoxifylline; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Protein kinase C regulates neurite outgrowth in spinal cord neurons.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activators; Enzyme Inhibitors; Indoles; Maleimides; Neurites; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Phagocytotic competence of differentiated U937 cells for colloidal drug delivery systems in immune cells.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Colloids; Drug Delivery Systems; Flow Cytometry; Gene Expression; Humans; Inflammation; Lipopolysaccharide Receptors; Microscopy, Confocal; Monocytes; Nanoparticles; Phagocytosis; Phosphatidylserines; Signal Transduction; Silicon Dioxide; Tetradecanoylphorbol Acetate; U937 Cells | 2011 |
Silencing Nogo-A promotes functional recovery in demyelinating disease.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; GAP-43 Protein; Gene Expression Regulation; Glycoproteins; Interferon-gamma; Interleukin-10; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myelin Basic Protein; Myelin Proteins; Myelin-Oligodendrocyte Glycoprotein; Neuroblastoma; Nogo Proteins; Peptide Fragments; RNA, Small Interfering; Spinal Cord; Tetradecanoylphorbol Acetate; Transfection | 2010 |
Chemopreventive properties of phytosterols and maslinic acid extracted from Coleus tuberosus in inhibiting the expression of EBV early-antigen in Raji cells.
Topics: Anticarcinogenic Agents; Antigens, Viral; Antineoplastic Agents, Phytogenic; Butyrates; Cell Line; Coleus; Herpesvirus 4, Human; Humans; Molecular Conformation; Phytosterols; Plant Tubers; Tetradecanoylphorbol Acetate; Triterpenes; Virus Activation | 2010 |
[Role of protein kinase C in protecting rats against pulmonary ischemia reperfusion injury through opening of mitochondrial ATP sensitive potassium channel].
Topics: Animals; Benzophenanthridines; Female; KATP Channels; Lung; Male; Mitochondria; Protein Kinase C; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetradecanoylphorbol Acetate | 2010 |
6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation.
Topics: Antineoplastic Agents; Breast Neoplasms; Catechols; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Female; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Matrix Metalloproteinases, Secreted; Neoplasm Invasiveness; NF-kappa B; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Zingiber officinale | 2010 |
Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-kappaB nuclear localization.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Croton Oil; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dermatitis; Dinoprostone; Down-Regulation; Edema; Humans; Inflammation Mediators; Isoflavones; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; NF-kappa B; Reactive Oxygen Species; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2010 |
LRRK2 is expressed in B-2 but not in B-1 B cells, and downregulated by cellular activation.
Topics: Animals; B-Lymphocyte Subsets; Down-Regulation; Female; Flow Cytometry; Ionomycin; Ionophores; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate | 2010 |
GH3B6 pituitary tumor cell proliferation is mediated by PKCalpha and PKCepsilon via ERK 1/2-dependent pathway.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Flavonoids; Flow Cytometry; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pituitary Neoplasms; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2010 |
MAP kinase activation increases BK polyomavirus replication and facilitates viral propagation in vitro.
Topics: Animals; Antigens, Polyomavirus Transforming; BK Virus; Cell Cycle; Chlorocebus aethiops; Cyclin D1; Enzyme Activation; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoblotting; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Polymerase Chain Reaction; Serum; Tetradecanoylphorbol Acetate; Vero Cells; Virus Activation | 2010 |
WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line.
Topics: Cell Differentiation; Cellular Reprogramming; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Multigene Family; Nerve Tissue Proteins; Neurites; Neurogenesis; Neurons; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Signal Transduction; Synapses; Tetradecanoylphorbol Acetate; Transcriptional Activation; WT1 Proteins | 2011 |
Theanine is a candidate amino acid for pharmacological stabilization of mast cells.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Cell Line; Gene Expression Regulation; Glutamates; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Male; Mast Cells; Mice; NF-kappa B; p-Methoxy-N-methylphenethylamine; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2012 |
Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death.
Topics: 4-Chloro-7-nitrobenzofurazan; Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Calcium; Cell Death; Coculture Techniques; Deoxyglucose; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; NAD; NADPH Oxidases; Neurons; Oxygen Consumption; Peptide Fragments; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2011 |
Identification of SH2B1β as a focal adhesion protein that regulates focal adhesion size and number.
Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion Molecules; Cell Line; Cell Movement; Cytoskeleton; Focal Adhesions; Growth Hormone; Mice; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Transport; Serine; Signal Transduction; Substrate Cycling; Tetradecanoylphorbol Acetate | 2011 |
Plant chitinase III Ziz m 1 stimulates multiple cytokines, most predominantly interleukin-13, from peripheral blood mononuclear cells of latex-fruit allergic patients.
Topics: Adult; Allergens; Antigens, Plant; Cells, Cultured; Chitinases; Cloning, Molecular; Cross Reactions; Cytokines; Escherichia coli; Female; Food Hypersensitivity; Humans; Interleukin-13; Latex Hypersensitivity; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Pichia; Plant Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Up-Regulation; Ziziphus | 2012 |
Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells.
Topics: Calcimycin; Calcineurin Inhibitors; Cell Differentiation; Cyclosporine; Gene Expression Regulation; HCT116 Cells; HT29 Cells; Humans; Intestinal Mucosa; Intestines; NFATC Transcription Factors; Signal Transduction; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2012 |
The decreased self-renewal potential of NPCs during human embryonic brain development with reduced activity of MAPKs.
Topics: Apoptosis; Brain; Cell Proliferation; Cells, Cultured; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate | 2012 |
Euphohelioscopin A is a PKC activator capable of inducing macrophage differentiation.
Topics: Antigens, CD34; Cell Differentiation; Cell Lineage; Cells, Cultured; Diterpenes; Granulocytes; HEK293 Cells; HeLa Cells; Hematopoietic Stem Cells; HL-60 Cells; Humans; Indoles; Macrophages; Maleimides; Protein Kinase C; Tetradecanoylphorbol Acetate | 2012 |
Inhibition of cytosolic Phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Ionomycin; Ketones; Mice; Neurons; Peptide Fragments; Phospholipases A2, Cytosolic; Prions; Protein Transport; Synaptophysin; Tetradecanoylphorbol Acetate; Time Factors; Tritium; Tubulin | 2012 |
Protein kinase C activation stimulates mesenchymal stem cell adhesion through activation of focal adhesion kinase.
Topics: Acetophenones; Animals; Benzopyrans; Cell Adhesion; Focal Adhesion Protein-Tyrosine Kinases; Integrins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Ischemia; Myocardium; Protein Kinase C; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate | 2013 |
Capsaicin induces theta-band synchronization between gustatory and autonomic insular cortices.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anoctamins; Biophysics; Calcium; Capsaicin; Cerebral Cortex; Chloride Channels; Diterpenes; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Membrane Potentials; Microscopy, Immunoelectron; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sensory System Agents; Subcellular Fractions; Tetradecanoylphorbol Acetate; Theta Rhythm; TRPV Cation Channels; Voltage-Sensitive Dye Imaging | 2012 |
Anti-inflammatory and apoptotic effects of the polyphenol curcumin on human fibroblast-like synoviocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis, Rheumatoid; Cell Line; Curcumin; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Interleukin-1beta; Interleukin-6; NF-kappa B; Polyphenols; Synovial Membrane; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2013 |
Altered prostanoid signaling contributes to increased skin tumorigenesis in Tpl2 knockout mice.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Prostaglandins; Proto-Oncogene Proteins; Receptors, Prostaglandin; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2013 |
Protein kinase C activation inhibits rat and human hyperpolarization activated cyclic nucleotide gated channel (HCN)1--mediated current in mammalian cells.
Topics: Animals; Cell Line; HEK293 Cells; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Indoles; Maleimides; Membrane Potentials; Mice; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate | 2013 |
Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction.
Topics: 14-3-3 Proteins; 5' Flanking Region; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Helicases; Female; Gene Expression Regulation; Histones; Humans; Nuclear Proteins; Nucleosomes; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; RNA Polymerase II; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Trefoil Factor-1; Tumor Suppressor Proteins | 2013 |
Synthesis and in vitro evaluation of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives as thymidine phosphorylase inhibitors.
Topics: Binding Sites; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Humans; Kinetics; Matrix Metalloproteinase 9; Molecular Docking Simulation; Protein Structure, Tertiary; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thermodynamics; Thymidine; Thymidine Phosphorylase; Triazines; Triazoles; Xanthines | 2013 |
Protein kinase Cα and P-type Ca channel CaV2.1 in red blood cell calcium signalling.
Topics: Agatoxins; Aniline Compounds; Calcium; Calcium Channels, N-Type; Calcium Signaling; Cell Membrane; Erythrocytes; Flow Cytometry; Hemolysis; Humans; Indoles; Kinetics; Lysophospholipids; Maleimides; Phosphatidylserines; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Xanthenes | 2013 |
Inhibitory effects of BiRyuChe-bang on mast cell-mediated allergic reactions and inflammatory cytokines production.
Topics: Animals; Calcimycin; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Histamine Release; Humans; Inflammation Mediators; Male; Mast Cells; Mice; Mice, Inbred ICR; Monoterpenes; NF-kappa B; Passive Cutaneous Anaphylaxis; Peritoneum; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2013 |
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Dendritic Cells; Female; Gene Expression Regulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Knockout; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Th1-Th2 Balance | 2014 |
KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Microinjections; Mutation; Nerve Tissue Proteins; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Sodium-Activated; Quinidine; Tetradecanoylphorbol Acetate; Time Factors; Voltage-Gated Sodium Channel Blockers; Xenopus laevis | 2014 |
Shikonin blocks migration and invasion of human breast cancer cells through inhibition of matrix metalloproteinase-9 activation.
Topics: Breast Neoplasms; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; MCF-7 Cells; Naphthoquinones; Neoplasm Invasiveness; Signal Transduction; Tetradecanoylphorbol Acetate | 2014 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
DPP-4 inhibitors repress NLRP3 inflammasome and interleukin-1beta via GLP-1 receptor in macrophages through protein kinase C pathway.
Topics: Carrier Proteins; Cell Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Dipeptidyl-Peptidase IV Inhibitors; Gene Expression Regulation; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Inflammasomes; Interleukin-1beta; Liraglutide; Macrophages; Nitriles; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Protein Kinase C; Pyrazines; Pyrrolidines; Receptors, Glucagon; Signal Transduction; Sitagliptin Phosphate; Tetradecanoylphorbol Acetate; Toll-Like Receptor 4; Triazoles | 2014 |
Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: recruiting histone deacetylase and inhibiting activator protein 1 transcription factors.
Topics: Cell Movement; Down-Regulation; Ginsenosides; Hep G2 Cells; Histone Deacetylases; Humans; Liver Neoplasms; Matrix Metalloproteinase 3; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2014 |
Oxidized low-density lipoprotein suppresses expression of prostaglandin E receptor subtype EP3 in human THP-1 macrophages.
Topics: Cell Differentiation; Cell Line; Gene Expression Regulation; Humans; Lipoproteins, LDL; Macrophages; NF-kappa B; Plaque, Atherosclerotic; PPAR gamma; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Tetradecanoylphorbol Acetate | 2014 |
Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Female; I-kappa B Proteins; Inflammation; Isothiocyanates; Lipopolysaccharides; Macrophages; Mice; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Skin; Tetradecanoylphorbol Acetate; Vegetables | 2014 |
Butein suppresses ICAM-1 expression through the inhibition of IκBα and c-Jun phosphorylation in TNF-α- and PMA-treated HUVECs.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Chalcones; Endothelial Cells; Gene Expression Regulation; Humans; I-kappa B Proteins; Immunosuppression Therapy; Intercellular Adhesion Molecule-1; Phosphorylation; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Umbilical Cord | 2015 |
Indirect detection of superoxide in RAW 264.7 macrophage cells using microchip electrophoresis coupled to laser-induced fluorescence.
Topics: Animals; Biosensing Techniques; Cell Survival; Electrophoresis, Microchip; Equipment Design; Equipment Failure Analysis; Fluorescent Dyes; Lasers; Metabolic Clearance Rate; Mice; Microscopy, Fluorescence; RAW 264.7 Cells; Reactive Oxygen Species; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Superoxides; Systems Integration; Tetradecanoylphorbol Acetate | 2015 |
Orexin-A potentiates L-type calcium/barium currents in rat retinal ganglion cells.
Topics: Animals; Animals, Newborn; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Membrane Potentials; Neurotransmitter Agents; Orexins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Tetradecanoylphorbol Acetate | 2015 |
Differential effects of myelin basic protein-activated Th1 and Th2 cells on the local immune microenvironment of injured spinal cord.
Topics: Adoptive Transfer; Analysis of Variance; Animals; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Macrophages; Motor Activity; Motor Disorders; Myelin Basic Protein; Nitric Oxide Synthase Type II; Psychomotor Performance; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord Injuries; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 2016 |
Protein Kinases Alter the Allosteric Modulation of the Serotonin Transporter In Vivo and In Vitro.
Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Carbazoles; Citalopram; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Indole Alkaloids; Male; Neurons; Protein Kinases; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Tetradecanoylphorbol Acetate | 2016 |
Oral administration of a novel RORγt antagonist attenuates psoriasis-like skin lesion of two independent mouse models through neutralization of IL-17.
Topics: Administration, Oral; Animals; Cell Differentiation; Cell Line, Tumor; Disease Models, Animal; Humans; Interleukin-17; Interleukin-23; Mice; Mice, Inbred BALB C; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Interleukin-17; Signal Transduction; Skin; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Th17 Cells | 2017 |
Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model.
Topics: Animals; CD4 Antigens; CD8 Antigens; Disease Models, Animal; Flow Cytometry; Humans; Immunohistochemistry; Inflammation; Interleukin-17; Interleukin-23 Subunit p19; Mice; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, CCR6; Skin; STAT3 Transcription Factor; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2017 |
Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model.
Topics: Animals; Anti-Inflammatory Agents; Antimicrobial Cationic Peptides; Disease Models, Animal; Ear; Female; Humans; Immunity, Innate; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred Strains; RAW 264.7 Cells; Teichoic Acids; Tetradecanoylphorbol Acetate; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2017 |
Rapamycin inhibits ox-LDL-induced inflammation in human endothelial cells in vitro by inhibiting the mTORC2/PKC/c-Fos pathway.
Topics: Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; E-Selectin; Gene Knockdown Techniques; Genes, fos; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Mechanistic Target of Rapamycin Complex 2; Protein Kinase C; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; RNA, Small Interfering; Signal Transduction; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate | 2018 |
Rapid flow cytometry-based assay for the evaluation of γδ T cell-mediated cytotoxicity.
Topics: Cell Differentiation; Cell Line; Coculture Techniques; Cytotoxicity, Immunologic; Flow Cytometry; Fluorescent Dyes; Humans; Intraepithelial Lymphocytes; Lipopolysaccharide Receptors; Microscopy, Fluorescence; Mycobacterium tuberculosis; Phagocytosis; Tetradecanoylphorbol Acetate | 2018 |
Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells.
Topics: Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Proliferation; Electromagnetic Fields; Humans; Leukemia, Promyelocytic, Acute; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tretinoin | 2018 |
Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation.
Topics: Animals; Antibodies, Neutralizing; CD4-Positive T-Lymphocytes; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Regulation; Humans; Imiquimod; Inflammation; Interleukin-7; Lymph Nodes; Lymphatic Vessels; Male; Mice; Mice, Inbred C57BL; Organ Specificity; Oxazolone; Psoriasis; Receptors, Interleukin-7; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2019 |
Decreased CD4
Topics: Adult; Biomarkers; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Correlation of Data; Disease Progression; HIV Infections; HIV-1; Humans; Interferon-gamma; Male; Tetradecanoylphorbol Acetate; Viral Load | 2020 |
Characterizing Innate Lymphoid Cell Phenotype and Function in Human Inflammatory Bowel Disease.
Topics: Colon; Cytokines; Flow Cytometry; Humans; Immunity, Innate; Inflammatory Bowel Diseases; Leukocytes, Mononuclear; Mucous Membrane; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2020 |
DK-1108 exerts anti-inflammatory activity against phorbol 12-myristate 13-acetate-induced inflammation and protective effect against OVA-induced allergic asthma.
Topics: A549 Cells; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Benzofurans; Dose-Response Relationship, Drug; Female; Humans; Inflammation Mediators; Mice; Mice, Inbred BALB C; Ovalbumin; RAW 264.7 Cells; Respiratory Hypersensitivity; Tetradecanoylphorbol Acetate | 2020 |
Specific NLRP3 Inhibition Protects Against Diabetes-Associated Atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Blood Glucose; Cells, Cultured; Fluorescent Antibody Technique; Glucose; Humans; Immunohistochemistry; Inflammasomes; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Tetradecanoylphorbol Acetate; THP-1 Cells; Tumor Necrosis Factor-alpha | 2021 |
The Oxidative Response of Human Monocytes to Surface Modified Commercially Pure Titanium.
Topics: Cells, Cultured; Coated Materials, Biocompatible; Humans; Luminescence; Monocytes; Osseointegration; Oxidation-Reduction; Oxidative Stress; Tetradecanoylphorbol Acetate; Titanium; Wound Healing | 2021 |