Compounds > 4-nitroquinoline-1-oxide
Page last updated: 2024-08-17

4-nitroquinoline-1-oxide and carbostyril

4-nitroquinoline-1-oxide has been researched along with carbostyril in 102 studies

Research

Studies (102)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (3.92)18.2507
2000's42 (41.18)29.6817
2010's48 (47.06)24.3611
2020's8 (7.84)2.80

Authors

AuthorsStudies
Chen, Z; Hendler, FJ; Oechsli, MN; Thomas, GR; Van Waes, C1
Galli, A; Schiestl, RH1
Furihata, C; Katsumura, Y; Kobayashi, H; Mori, M; Sugiyama, C1
Ladiges, WC; Martin, GM; Ogburn, CE; Oshima, J; Wang, L; Ware, CB; Youssoufian, H1
Henriques, JA; Pereira, VR; Saffi, J1
Honjo, S; Kawabata, K; Kohno, H; Murakami, M; Ota, T; Tanaka, T; Tsuda, H1
Beard, C; Bronson, R; Buhlmann, JE; Curry, R; Dausman, J; Guarente, L; Jaenisch, R; Johnson, B; Lipman, R; Lombard, DB; Marciniak, RA; Sharpe, A1
Ham, JH; Han, YH; Lee, DU; Lee, NJ; Park, CH; Shin, YH1
Dayan, D; Engelberg, J; Kaplan, I1
Boothman, DA; Dubyak, GR; Nieminen, AL; Pink, JJ; Tagliarino, C1
Gruz, P; Kim, SR; Matsui, K; Nohmi, T; Yamada, M1
Lobysheva, II; Mikoyan, VD; Stupakova, MV; Vanin, AF; Vasil'eva, SV1
Mori, H; Moriwaki, H; Okuno, M; Sugie, S; Suzui, M; Tanaka, T1
Chen, W; He, R; Liu, X1
He, R; Liu, X; Zhou, Z1
Bohr, VA; Brosh, RM; Muftuoglu, M; Selzer, R; Tuo, J1
Hirose, Y; Kohno, H; Mori, H; Sakata, K; Sugie, S; Tanaka, T; Yamada, Y1
Dahm, K; Hübscher, U1
Kohno, H; Nomura, E; Tanaka, T; Taniguchi, H; Tsuda, H; Tsuno, T1
Horn, RC; Vargas, VM1
Chagnon, MC; Le Bon, AM; Le Hegarat, L; Lhuguenot, JC; Valentin-Severin, I1
Dong, Z; Fasullo, M1
Aguilera, A; García-Rubio, M; González-Barrera, S; Huertas, P1
Castañeda-Partida, L; Contreras-Sousa, M; Dueñas-García, I; Durán-Díaz, A; Graf, U; Heres-Pulido, ME; Sánchez-García, A1
Kramer, W; Rudolph, C; Schürer, KA; Ulrich, HD1
Fatigoni, C; Grover, IS; Kaur, LS; Kumar, S; Marcarelli, LM; Moretti, LM; Pasquini, R; Scassellati-Sforzolini, G; Villarini, LM1
Denda, A; Inoue, M; Kirita, T; Kitayama, W; Kuniyasu, H; Morisaki, A; Yamamoto, K1
Byun, Y; Choi, Y; Kim, SY; Lee, C; Park, K; Yang, JH1
Becker, KG; Bohr, VA; Kyng, KJ; Kølvrå, S; May, A; Stevnsner, T1
Boccioli, B; Moretti, M; Pasquini, R; Scassellati-Sforzolini, G; Villarini, M1
Barbour, L; Hanna, M; Xiao, W1
Califano, JA; Chatterjee, A; Glazer, CA; Kim, MM; Mambo, E; Sidransky, D; Zhao, M1
Arizono, K; Ishibashi, H; Kawahara, T; Nomura, Y; Okazaki, M; Tanaka, N; Teshima, W1
Ito, T; Miyagi, Y; Udaka, N1
Belaidi, JP; Bourouf, L; Dourille, E; Feltes, M; Flamand, N; Marrot, L; Meunier, JR1
Alvarez Leite, J; da Silva Fonseca, LM; Ferreira de Aguiar, MC; Gomes Dos Reis, D; Vieira do Carmo, MA; Vitorino Cardoso, S1
Buscemi, G; Canevari, S; Carlessi, L; Delia, D; Fontanella, E; Lisanti, S; Zannini, L1
Aouida, M; Belhadj, O; Leduc, A; Poschmann, J; Ramotar, D; Tounekti, K; Yang, X1
Prakash, L; Prakash, S; Ribar, B1
Denda, A; Kirita, T; Kitayama, W; Kuniyasu, H; Sasahira, T; Yamamoto, K1
Amin, S; Bruggeman, R; Chen, KM; Desai, D; El-Bayoumy, K; Guttenplan, J; Hennessy, J; Khmelnitsky, M; Kosinska, W; Spratt, TE; Sun, YW1
Ishigamori-Suzuki, R; Kim, M; Miyamoto, S; Murakami, A; Sugie, S; Tanaka, T; Yasui, Y1
Haug, SR; Heyeraas, KJ; Ibrahim, SO; Raju, B1
Chabes, A; Goyal, DK; Johansson, E; Sabouri, N; Viberg, J1
Aguilera, A; de la Loza, MC; Wellinger, RE1
Adema, GJ; Berden, JH; Fransen, JH; Hilbrands, LB; Ruben, J; Stoffels, M; van der Vlag, J1
Castañeda-Partida, L; Dueñas-García, I; Durán-Díaz, A; Gómez-Luna, JC; Heres-Pulido, ME; Rebollar-Vega, R; Santos-Cruz, LF; Vega-Contreras, V1
Chandel, M; Kaur, P; Kaur, S; Kumar, N; Kumar, S; Singh, B1
Iwanaga, E; Miyamoto, K; Miyamoto, Y; Oshida, K1
Abrahams, GL; Gordhan, BG; Kana, BD; Kaplan, G; Machowski, EE; Mizrahi, V; Sacchettini, JC; Stoker, NG; Sung, N; Tsenova, L; Warner, DF1
Caudy, AA; Ehrenreich, IM; Gresham, D; Jia, Y; Kent, J; Kruglyak, L; Martis, S; Shapiro, JA; Torabi, N1
Grawish, ME; Zaher, AR; Zyada, MM1
Han, Z; Kong, Q; Li, H; Liu, Y; Mu, L; Sun, B; Wang, D; Wang, G; Wang, J; Zhang, S1
Cohen, SE; Collins, JJ; Kohanski, MA; Landick, R; Lewis, CA; Mooney, RA; Walker, GC1
Duensing, S; Grompe, M; Lambert, PF; Park, JW; Pitot, HC; Spardy, N; Strati, K1
Doçi, CL; Hasina, R; Lingen, MW; Mankame, TP; Wroblewski, K; Zhou, G1
Aström, SU; Barsoum, E; Chabes, A; Tsaponina, O1
Peyroche, A; Tallec, BL1
Fry, RC; Samson, LD; Somoza, LA; Svensson, JP; Wang, E1
Bae, KH; Bang, SY; Kim, JH; Kim, PS; Lee, DH; Lee, JS; Lee, PY; Myung, PK; Park, BC; Park, SG1
Feith, DJ; Fong, LY; Pegg, AE1
Gudas, LJ; Scognamiglio, T; Tang, XH1
Barcessat, AR; Corrêa, L; dos Santos Pinto, D; Huang, I; Maria Zezell, D; Rosin, FP1
Hsu, TC; Wu, X; Zheng, YL1
Barcessat, AR; Corrêa, L; de Cerqueira Luz, JG; Ferreira, LG; Huang, I; Rabelo, GD; Rosin, FC1
Alvarenga, TA; Andersen, ML; Marchi, P; Noguti, J; Oshima, CT; Ribeiro, DA1
Chen, MF; Chen, WC; Chung, YH; Kuan, FC; Lee, KD; Lin, PY; Lu, MS; Yen, TC1
Curylofo, FA; Gonçalves, Vde P; Guimarães, MR; Ortega, AA; Ribeiro, DA; Rossa Junior, C; Spolidorio, LC1
Abbasi, MM; Hamishehkar, H; Jahanban-Esfahlan, R; Khiavi, MM; Monfaredan, A; Seidi, K1
Anthonissen, R; Light, ME; Maes, A; Pošta, M; Van Staden, J; Verschaeve, L1
Chen, MF; Chen, PT; Chen, WC; Hsieh, CC; Lin, PY; Wu, CT; Yen, TC1
Dinesdurage, HR; Elbekai, RH; Proctor, DM; Rohr, AC; Suh, M; Thompson, CM; Young, RR1
Das, SK; Dash, R; Fisher, PB; Maji, S; Panda, S; Pattanaik, L; Pellecchia, M; Quinn, BA; Samal, SK; Sarkar, D1
Bothwell, KD; Hershberger, PA; Johnson, CS; Kuriakose, MA; Merzianu, M; Seshadri, M; Shaurova, T; Suresh, A1
Gudas, LJ; Osei-Sarfo, K; Scognamiglio, T; Tang, XH; Urvalek, AM; Zhang, T1
Abraham, SK; Hintzsche, H; Khandelwal, N; Stopper, H1
Alharbi, Y; Baggelaar, PK; Kruithof, JC; Martijn, BJ; Penders, EJ; Rietjens, IM; Van Rompay, AR1
Cao, NN; Li, PF; Man, HW; Shan, BE; Wang, L; Wang, S1
Horn, TL; Johnson, WD; Lubet, RA; McCormick, DL; Peng, X; Steele, VE1
D'Amours, D; Pascariu, M; Ratsima, H; Serrano, D1
Bertolus, C; Caulin, C; Chabaud, S; Foy, JP; Goudot, P; Hong, WK; Lachuer, J; Lang, W; Lavergne, E; Le Texier, V; Lippman, SM; Perol, D; Saintigny, P; Thomas, E; Tortereau, A1
Balasubramanian, N; Bhandari, R; Buwa, N; Ganguli, S; Jadav, RS; Kumar, D; Thampatty, SR1
Gion, Y; Hanakawa, H; Ito, T; Makino, T; Marunaka, H; Matsukawa, A; Miki, K; Minoura, A; Nishizaki, K; Ohno, K; Orita, Y; Sato, Y; Tachibana, T; Takao, S; Takeuchi, M; Yoshino, T1
Bikle, DD; Chen, Y; Deng, X; Ji, S; Jiang, Y; Liao, E; Liao, L; Shrestha, C; Xie, Z; Yuan, Y1
Barcessat, AR; Borges, GG; Corrêa, L; Ferreira, LG; Rosin, FC1
Devaki, T; Gopikrishnan, M; Madankumar, A; Nagabhishek, N; Premkumar, T; Tamilarasi, S1
Caulin, C; El-Naggar, AK; Heymach, JV; Myers, JN; Wang, B; Wang, J; William, WN; Xie, T1
Chen, X; Cheng, B; Hu, Q; Wang, C; Wu, T; Xia, J; Yang, L1
El-Naggar, AK; Fan, YH; Feng, L; Foy, JP; Hong, WK; Kim, ES; Lang, W; Lee, JJ; Lingen, MW; Lippman, SM; Mao, L; Papadimitrakopoulou, V; Saintigny, P; William, WN; Zhang, L1
Choi, JE; Chung, WH; Heo, SH; Kim, MJ1
Karpov, DS; Karpov, VL; Lysov, YP; Nadolinskaia, NI; Spasskaya, DS; Tutyaeva, VV1
Bailey, LJ; Bianchi, J; Doherty, AJ1
Kurata, M; Nemoto, S; Sadamoto, K; Tahara, H; Yamagiwa, Y1
McLoughlin, F; Simms, CL; Vierstra, RD; Yan, LL; Zaher, HS1
Callejas-Valera, JL; Gillenwater, AM; Richards-Kortum, RR; Schwarz, RA; Tan, MT; Vigneswaran, N; Wu, JG1
Bailey, LJ; Bowry, A; Bryant, HE; Doherty, AJ; González-Acosta, D; Kelly, RDW; Méndez, J; Morris, JR; Petermann, E; Piberger, AL; Walker, AK1
Hartgerink, JD; Leach, DG; Myers, JN; Osman, AA; Rangel, R; Ren, X; Shi, Y; Sikora, AG; Wang, B; Xie, TX; Young, S1
Chen, G; Li, XM; Liu, X; Lu, GY; Xu, J; Yao, J; Zhu, FY1
Chao, JL; Higgins, K; Izumchenko, E; Korzinkin, M; Lingen, MW; Ozerov, IV; Savage, PA; Walker, MT; Zhavoronkov, A1
Ali, M; Bure, L; Chen, JW; Cheng, YS; Curtin, H; Forghani, R; Iwamoto, Y; Jalali Motlagh, N; Li, A; Li, JH; Papadakis, AI; Pusztaszeri, MP; Spatz, A; Wang, C; Wojtkiewicz, GR; Wu, Y1
Aizenbud, I; Amit, I; Barel, O; Capucha, T; Czerninski, R; David, E; Eli-Berchoer, L; Hovav, AH; Koren, N; Matanes, D; Saba, Y; Stoitzner, P; Wilensky, A; Yona, S; Zubeidat, K1
Coppes, RP; Du, L; Gao, S; Li, F; Li, K; Liu, F; Luo, Y; Pan, Y; Yao, Z; Zhang, D; Zhang, H; Zhu, J1

Trials

1 trial(s) available for 4-nitroquinoline-1-oxide and carbostyril

ArticleYear
Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer.
    Journal of the National Cancer Institute, 2018, 03-01, Volume: 110, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Cell Proliferation; Crizotinib; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Genomics; Head and Neck Neoplasms; Humans; Leukoplakia, Oral; Male; Mice, Inbred CBA; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; Precancerous Conditions; Prognosis; Prospective Studies; Proto-Oncogene Proteins c-met; Pyrrolidinones; Quinolines; Quinolones; Survival Rate; Tumor Cells, Cultured

2018

Other Studies

101 other study(ies) available for 4-nitroquinoline-1-oxide and carbostyril

ArticleYear
Decreased expression of CD80 is a marker for increased tumorigenicity in a new murine model of oral squamous-cell carcinoma.
    International journal of cancer, 1999, Jul-30, Volume: 82, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Animals, Congenic; B7-1 Antigen; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Transformed; Clone Cells; Histocompatibility Antigens Class I; Immunocompetence; Lymphocyte Count; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Mouth Neoplasms; Phenotype; Quinolones; Severe Combined Immunodeficiency

1999
Cell division transforms mutagenic lesions into deletion-recombinagenic lesions in yeast cells.
    Mutation research, 1999, Aug-11, Volume: 429, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; CDC28 Protein Kinase, S cerevisiae; Cell Division; Chromosome Deletion; DNA, Fungal; Ethyl Methanesulfonate; Fungal Proteins; G1 Phase; G2 Phase; Gamma Rays; Methyl Methanesulfonate; Mutagenesis; Mutagenicity Tests; Mutagens; Point Mutation; Quinolones; Recombination, Genetic; Saccharomyces cerevisiae; Ultraviolet Rays

1999
Induction of unscheduled DNA synthesis in hairless mouse epidermis by skin carcinogens.
    The Journal of toxicological sciences, 1999, Volume: 24, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; DNA; DNA Damage; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Hydroxyurea; Methylnitronitrosoguanidine; Mice; Mice, Hairless; Quinolones; Skin

1999
Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene.
    Genetics, 2000, Volume: 154, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Alleles; Animals; Cell Division; DNA Helicases; Down-Regulation; Exodeoxyribonucleases; Genes, Dominant; Humans; Mice; Mice, Transgenic; Phenotype; Quinolones; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase

2000
Importance of the Sgs1 helicase activity in DNA repair of Saccharomyces cerevisiae.
    Current genetics, 2000, Volume: 37, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Cell Division; DNA Helicases; DNA Repair; Hydrogen Peroxide; Hydroxyurea; Mechlorethamine; Methyl Methanesulfonate; Mutagens; Mutation; Quinolones; RecQ Helicases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ultraviolet Rays

2000
Chemopreventive effect of bovine lactoferrin on 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats.
    Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Body Weight; Carcinogens; Cattle; Epithelium; Glutathione Transferase; Immunohistochemistry; Lactoferrin; Liver; Male; Mucous Membrane; NAD(P)H Dehydrogenase (Quinone); Organ Size; Ornithine Decarboxylase; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Quinolones; Rats; Rats, Inbred F344; Tongue; Tongue Neoplasms

2000
Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
    Molecular and cellular biology, 2000, Volume: 20, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Animals; Blotting, Western; Camptothecin; Cell Division; Cells, Cultured; Cellular Senescence; Cloning, Molecular; DNA Helicases; Dose-Response Relationship, Drug; Embryo, Mammalian; Exodeoxyribonucleases; Fibroblasts; Gene Library; Life Expectancy; Mice; Mice, Knockout; Molecular Sequence Data; Mutation; Phenotype; Quinolones; RecQ Helicases; Spleen; Time Factors; Tissue Distribution; Tumor Suppressor Protein p53; Werner Syndrome Helicase

2000
Antimutagenic activity of 5alpha-cholest-7-en-3beta-ol, a new component from the starfish asterina pectinifera.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Cholesterol; Escherichia coli; Methylnitronitrosoguanidine; Quinolones; Salmonella typhimurium; Starfish; Tissue Extracts

2000
The effect of desalivation on 4-nitroquinoline-1-oxide-induced tongue carcinogenesis: a morphometric study of nucleolar organizer regions.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2001, Volume: 30, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Analysis of Variance; Animals; Carcinogens; Cell Transformation, Neoplastic; Image Processing, Computer-Assisted; Male; Nucleolus Organizer Region; Quinolones; Rats; Rats, Wistar; Saliva; Silver Staining; Statistics, Nonparametric; Tongue Neoplasms

2001
Calcium is a key signaling molecule in beta-lapachone-mediated cell death.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: 4-Nitroquinoline-1-oxide; Adenosine Triphosphate; Apoptosis; Blotting, Western; Breast Neoplasms; Calcium; Cell Death; Cell Division; Chelating Agents; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Endoplasmic Reticulum; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Models, Biological; Naphthoquinones; Prostatic Neoplasms; Quinolones; Signal Transduction; Time Factors; Tumor Cells, Cultured

2001
Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli.
    Molecular genetics and genomics : MGG, 2001, Volume: 266, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Chromosomes, Bacterial; DNA Polymerase beta; Dose-Response Relationship, Drug; Escherichia coli; Frameshift Mutation; Gene Expression Regulation, Enzymologic; Mutagenesis; Plasmids; Quinolones

2001
Activation of the Escherichia coli SoxRS-regulon by nitric oxide and its physiological donors.
    Biochemistry. Biokhimiia, 2001, Volume: 66, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Bacterial Proteins; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Iron; Iron Chelating Agents; Ligands; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Quinolones; Regulon; S-Nitrosothiols; Trans-Activators; Transcription Factors

2001
Different mutation status of the beta-catenin gene in carcinogen-induced colon, brain, and oral tumors in rats.
    Molecular carcinogenesis, 2001, Volume: 32, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anthraquinones; beta Catenin; Brain Neoplasms; Carcinogens; Colonic Neoplasms; Cytoskeletal Proteins; Genetic Markers; Male; Methylazoxymethanol Acetate; Mouth Neoplasms; Mutation; Nitrosourea Compounds; Organ Specificity; Polymerase Chain Reaction; Quinolones; Rats; Rats, Inbred F344; Trans-Activators

2001
[The expression of RAR beta mRNA in rat tongue carcinogenesis].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2000, Volume: 35, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Down-Regulation; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; RNA, Messenger; Tongue Neoplasms

2000
[Telomerase activity in rat tongue carcinogenesis].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2000, Volume: 35, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Disease Models, Animal; Quinolones; Rats; Rats, Sprague-Dawley; Telomerase; Tongue Neoplasms

2000
Phenotypic consequences of mutations in the conserved motifs of the putative helicase domain of the human Cockayne syndrome group B gene.
    Gene, 2002, Jan-23, Volume: 283, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Amino Acid Motifs; Amino Acid Sequence; Cell Survival; Conserved Sequence; DNA Helicases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gene Expression Regulation; Humans; Immunoblotting; Mutation; Phenotype; Poly-ADP-Ribose Binding Proteins; Quinolones; RNA; Sequence Homology, Amino Acid; Transcription, Genetic; Transfection; Ultraviolet Rays

2002
Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.
    Carcinogenesis, 2002, Volume: 23, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Biogenic Polyamines; Capsaicin; Carcinogens; Diet; Glutathione Transferase; Male; NAD(P)H Dehydrogenase (Quinone); Proliferating Cell Nuclear Antigen; Quinolones; Rats; Rats, Inbred F344; Rotenone; Tongue; Tongue Neoplasms

2002
Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block.
    Oncogene, 2002, Oct-31, Volume: 21, Issue:50

    Topics: 4-Nitroquinoline-1-oxide; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; DNA Replication; DNA-Binding Proteins; HeLa Cells; Humans; Hydroxyurea; Proliferating Cell Nuclear Antigen; Quinolones; Replication Protein C; S Phase

2002
A novel geranylated derivative, ethyl 3-(4'-geranyloxy-3'-methoxyphenyl)-2-propenoate, synthesized from ferulic acid suppresses carcinogenesis and inducible nitric oxide synthase in rat tongue.
    Oncology, 2003, Volume: 64, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Carcinogens; Cell Division; Coumaric Acids; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Incidence; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proliferating Cell Nuclear Antigen; Quinolones; Rats; Rats, Inbred F344; Terpenes; Tongue Neoplasms

2003
Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay.
    Mutagenesis, 2003, Volume: 18, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Aflatoxins; Animals; Anthracenes; Antimutagenic Agents; Dose-Response Relationship, Drug; Fluorenes; Frameshift Mutation; Maytenus; Microsomes; Mutagenicity Tests; Mutagens; Mutation; Quinolones; Rats; Rats, Sprague-Dawley; Salmonella; Sodium Azide; Temperature

2003
Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
    Mutation research, 2003, Apr-20, Volume: 536, Issue:1-2

    Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet Assay; Dimethylnitrosamine; Humans; Inhibitory Concentration 50; Liver Neoplasms; Methyl Methanesulfonate; Micronucleus Tests; Mutagens; Nitrosamines; Quinolones; Sensitivity and Specificity; Tumor Cells, Cultured

2003
Multiple recombination pathways for sister chromatid exchange in Saccharomyces cerevisiae: role of RAD1 and the RAD52 epistasis group genes.
    Nucleic acids research, 2003, May-15, Volume: 31, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Cell Division; Deoxyribonucleases, Type II Site-Specific; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Endonucleases; Epistasis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Methyl Methanesulfonate; Mutation; Quinolones; Rad51 Recombinase; Rad52 DNA Repair and Recombination Protein; Recombination, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sister Chromatid Exchange; Ultraviolet Rays; X-Rays

2003
Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination.
    Genetics, 2003, Volume: 165, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Chromosomes; DNA Damage; Methyl Methanesulfonate; Mutagens; Plasmids; Quinolones; Recombination, Genetic; Saccharomyces cerevisiae; Transcription, Genetic; Vitamin K 3

2003
Genotoxicity of tamoxifen citrate and 4-nitroquinoline-1-oxide in the wing spot test of Drosophila melanogaster.
    Mutagenesis, 2004, Volume: 19, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Breast Neoplasms; Carcinogens; Dimethylnitrosamine; Drosophila melanogaster; Female; Humans; Larva; Nitrosamines; Quinolones; Tamoxifen; Wings, Animal

2004
Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.
    Genetics, 2004, Volume: 166, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Culture Media; DEAD-box RNA Helicases; DNA Damage; Genes, Fungal; Genotype; Methyl Methanesulfonate; Mutation; Plasmids; Quinolones; Recombination, Genetic; RNA Helicases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2004
Antigenotoxic properties of Terminalia arjuna bark extracts.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1999, Volume: 18, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Antimutagenic Agents; Comet Assay; DNA Damage; Medicine, Ayurvedic; Micronucleus Tests; Mutagens; Plant Extracts; Quinolones; Solvents; Terminalia

1999
Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2004, Volume: 56, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Chemoprevention; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Etodolac; Immunohistochemistry; Male; Precancerous Conditions; Quinolones; Rats; Rats, Inbred F344; Tongue; Tongue Neoplasms; Water Supply

2004
Chemoprevention of 4-NQO-induced oral carcinogenesis by co-administration of all-trans retinoic acid loaded microspheres and celecoxib.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, May-05, Volume: 104, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Celecoxib; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Drug Therapy, Combination; Female; Liposomes; Male; Pyrazoles; Quinolones; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sulfonamides; Tongue Neoplasms; Tretinoin

2005
Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome.
    Oncogene, 2005, Jul-28, Volume: 24, Issue:32

    Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Aging; Cell Line; DNA Damage; Fibroblasts; Gamma Rays; Gene Expression Regulation; Genes, Immediate-Early; Humans; Oligonucleotide Array Sequence Analysis; Quinolones; Skin; Stress, Physiological; Ultraviolet Rays; Werner Syndrome

2005
Effects of co-exposure to extremely low frequency (50 Hz) magnetic fields and xenobiotics determined in vitro by the alkaline comet assay.
    The Science of the total environment, 2006, May-15, Volume: 361, Issue:1-3

    Topics: 4-Nitroquinoline-1-oxide; Adult; Comet Assay; DNA Damage; Glutathione; Humans; Leukocytes; Magnetics; Male; Methylnitronitrosoguanidine; Mutagens; Quinolones; Xenobiotics

2006
Mutagenesis.
    Methods in molecular biology (Clifton, N.J.), 2006, Volume: 313

    Topics: 4-Nitroquinoline-1-oxide; Aminacrine; Ethyl Methanesulfonate; Genes, Fungal; Methylnitronitrosoguanidine; Mutagenesis; Mutagens; Mycology; Nitrogen Mustard Compounds; Quinolones; Saccharomyces cerevisiae; Ultraviolet Rays

2006
Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO.
    Oral oncology, 2006, Volume: 42, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Carcinoma, Squamous Cell; DNA Adducts; DNA Damage; DNA Repair; DNA, Mitochondrial; DNA, Neoplasm; Head and Neck Neoplasms; Humans; Oxidative Stress; Polymerase Chain Reaction; Quinolones; Tumor Cells, Cultured

2006
Genotoxicity of dental resin polymerization initiators in vitro.
    Journal of materials science. Materials in medicine, 2006, Volume: 17, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Acetone; Benzoyl Peroxide; Biocompatible Materials; Camphor; Composite Resins; Dental Materials; Dose-Response Relationship, Drug; Ethylamines; In Vitro Techniques; Inhibitory Concentration 50; Light; Methacrylates; Molecular Structure; Mutagenicity Tests; Photosensitizing Agents; Quinolones; Reducing Agents; Solutions; Sulfonium Compounds; Thiourea; Toluidines

2006
Connexin expression in mouse lung tumor.
    Cancer letters, 2007, Feb-08, Volume: 246, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Blotting, Western; Connexin 26; Connexin 43; Connexins; Gap Junction alpha-4 Protein; Gap Junction alpha-5 Protein; Gap Junction beta-1 Protein; Gene Expression Regulation, Neoplastic; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Phosphorylation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2007
Development of genotoxicity test procedures with Episkin, a reconstructed human skin model: towards new tools for in vitro risk assessment of dermally applied compounds?
    Mutation research, 2006, Jul-14, Volume: 606, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Administration, Cutaneous; Animals; Cells, Cultured; Coculture Techniques; Comet Assay; DNA Damage; Epidermis; Humans; Mice; Models, Biological; Mutagenicity Tests; Photosensitizing Agents; Quinolones; Risk Assessment; Skin Irritancy Tests; Skin, Artificial; Sunscreening Agents; Tissue Engineering; Ultraviolet Rays

2006
Immunohistochemical evaluation of metallothionein in palatal mucosal cells of mice treated with 4NQO.
    Medicina oral, patologia oral y cirugia bucal, 2006, Jul-01, Volume: 11, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Immunohistochemistry; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mouth Mucosa; Palate, Soft; Quinolones

2006
DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues.
    Molecular and cellular biology, 2006, Volume: 26, Issue:21

    Topics: 4-Nitroquinoline-1-oxide; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydroxyurea; Multiprotein Complexes; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quinolones; Radiation, Ionizing; Recombinant Fusion Proteins; RNA Interference; Serine; Tumor Suppressor Proteins

2006
Deletion of the chromatin remodeling gene SPT10 sensitizes yeast cells to a subclass of DNA-damaging agents.
    Environmental and molecular mutagenesis, 2006, Volume: 47, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Bleomycin; Chromatin; DNA Damage; DNA Repair; Gamma Rays; Histone Acetyltransferases; Hydrogen Peroxide; Methyl Methanesulfonate; Mutagens; Phleomycins; Quinolones; Rad51 Recombinase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Ultraviolet Rays

2006
ELA1 and CUL3 are required along with ELC1 for RNA polymerase II polyubiquitylation and degradation in DNA-damaged yeast cells.
    Molecular and cellular biology, 2007, Volume: 27, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Cullin Proteins; DNA Damage; Elongin; Mutation; Polyubiquitin; Protein Processing, Post-Translational; Quinolones; RNA Polymerase II; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Ultraviolet Rays

2007
Expression of receptor for advanced glycation end products during rat tongue carcinogenesis by 4-nitroquinoline 1-oxide and effect of a selective cyclooxygenase-2 inhibitor, etodolac.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 2006, Volume: 73, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Etodolac; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Male; Quinolones; Rats; Rats, Inbred F344; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tongue; Tongue Neoplasms

2006
Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide.
    Mutation research, 2007, Dec-01, Volume: 634, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Animals, Genetically Modified; Anticarcinogenic Agents; Carcinogens; Mutagens; Organoselenium Compounds; Quinolones; Rats; Rats, Inbred F344; Tongue; Tongue Neoplasms; Tumor Suppressor Protein p53

2007
A novel rasH2 mouse carcinogenesis model that is highly susceptible to 4-NQO-induced tongue and esophageal carcinogenesis is useful for preclinical chemoprevention studies.
    Carcinogenesis, 2008, Volume: 29, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Cell Proliferation; Dinoprostone; Esophageal Neoplasms; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; Oncogene Protein p21(ras); Prostaglandin-Endoperoxide Synthases; Quinolones; Tongue Neoplasms

2008
High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2008, Volume: 37, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Analysis of Variance; Animals; Body Weight; Carcinoma, Squamous Cell; Extracellular Fluid; Lymphatic Vessels; Male; Neoplasm Invasiveness; Pressure; Quinolones; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tongue Neoplasms

2008
Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage.
    Nucleic acids research, 2008, Volume: 36, Issue:17

    Topics: 4-Nitroquinoline-1-oxide; Deoxyribonucleotides; DNA Damage; DNA Polymerase II; DNA Replication; DNA-Directed DNA Polymerase; Gene Deletion; Guanine; Mutation; Quinolones; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; S Phase; Saccharomyces cerevisiae

2008
Stimulation of direct-repeat recombination by RNA polymerase III transcription.
    DNA repair, 2009, May-01, Volume: 8, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Blotting, Northern; DNA Helicases; DNA Replication; DNA, Fungal; Gene Expression Regulation, Fungal; Quinolones; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; RNA Polymerase III; RNA, Transfer; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription, Genetic

2009
Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Autoantigens; Bone Marrow Cells; Cell Differentiation; Cell Surface Extensions; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Flow Cytometry; Humans; Interleukin-17; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Microscopy, Confocal; Phagocytosis; Quinolones; T-Lymphocytes

2009
Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Brassica; Cytochromes; DNA; DNA Adducts; Drosophila melanogaster; Food, Organic; Free Radical Scavengers; Freeze Drying; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Purines; Quinolones; Reactive Oxygen Species; Ultraviolet Rays; Urethane; Wings, Animal

2010
Modulatory role of alizarin from Rubia cordifolia L. against genotoxicity of mutagens.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Anthraquinones; Antimutagenic Agents; Catechols; Chromatography, Thin Layer; Comet Assay; Escherichia coli; Fluorenes; Humans; Hydrogen Peroxide; Lymphocytes; Magnetic Resonance Spectroscopy; Mutagenicity Tests; Mutagens; Organometallic Compounds; Oxidants; Plant Roots; Quinolones; Rubia; Salmonella typhimurium

2010
Comet assay in murine bone-marrow cell line (FDC-P2).
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Benzo(a)pyrene; Bone Marrow Cells; Cell Line; Cell Survival; Comet Assay; Cyclophosphamide; DNA; DNA Damage; Dose-Response Relationship, Drug; Methyl Methanesulfonate; Mutagens; Quinolones; Rats; Subcellular Fractions

2010
Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis.
    Journal of bacteriology, 2010, Volume: 192, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Acrolein; Animals; Bacterial Proteins; Benzopyrenes; Cells, Cultured; Female; Humans; Macrophages; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitrofurazone; Protein Binding; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Two-Hybrid System Techniques

2010
Dissection of genetically complex traits with extremely large pools of yeast segregants.
    Nature, 2010, Apr-15, Volume: 464, Issue:7291

    Topics: 4-Nitroquinoline-1-oxide; Chromosome Mapping; Crosses, Genetic; Diploidy; Drug Resistance, Fungal; Gene Frequency; Genotype; Haploidy; Mitochondria; Multifactorial Inheritance; Oligonucleotide Array Sequence Analysis; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Quinolones; Saccharomyces cerevisiae; Sample Size

2010
Inhibition of 4-NQO-induced F433 rat tongue carcinogenesis by oleuropein-rich extract.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Immunohistochemistry; Iridoid Glucosides; Iridoids; Ki-67 Antigen; Male; Olea; Phytotherapy; Plant Extracts; Plant Leaves; Proto-Oncogene Proteins c-met; Pyrans; Quinolones; Rats; Rats, Inbred F344; Tongue Neoplasms

2011
Malignant transformation of rat bone marrow-derived mesenchymal stem cells treated with 4-nitroquinoline 1-oxide.
    Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Female; Karyotyping; Mesenchymal Stem Cells; Mice; Mice, Inbred ICR; Quinolones; Rats; Rats, Sprague-Dawley; Telomerase

2010
Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Aug-31, Volume: 107, Issue:35

    Topics: 4-Nitroquinoline-1-oxide; Anti-Infective Agents; Blotting, Far-Western; DNA Damage; DNA Repair; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Green Fluorescent Proteins; Microbial Viability; Microscopy, Fluorescence; Mutation; Nitrofurazone; Peptide Elongation Factors; Quinolones; Rec A Recombinases; Signal Transduction; Temperature; Transcription Factors; Transcription, Genetic; Transcriptional Elongation Factors

2010
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.
    Cancer research, 2010, Dec-01, Volume: 70, Issue:23

    Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; DNA Damage; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Female; Fluorescent Antibody Technique; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Male; Mice; Mice, 129 Strain; Mice, Knockout; Mice, Transgenic; Papillomavirus E7 Proteins; Quinolones; Signal Transduction

2010
Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:11

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Immunohistochemistry; Mice; Mice, Inbred CBA; Mouth Neoplasms; Neovascularization, Pathologic; Piperidines; Quinazolines; Quinolones; Receptors, Vascular Endothelial Growth Factor

2010
Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools.
    PLoS genetics, 2011, Volume: 7, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Amino Acid Sequence; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Gene Order; High Mobility Group Proteins; Histones; Hydroxyurea; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Phenotype; Protein Serine-Threonine Kinases; Quinolones; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Transcription, Genetic

2011
Using DNA damage sensitivity phenotypes to characterize mutations affecting proteasome function.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 832

    Topics: 4-Nitroquinoline-1-oxide; Camptothecin; Canavanine; DNA Damage; Methyl Methanesulfonate; Mutation; Polyubiquitin; Proteasome Endopeptidase Complex; Quinolones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2012
Identification of novel human damage response proteins targeted through yeast orthology.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Autophagy; Cell Line; Chromatin Assembly and Disassembly; DNA Damage; DNA Repair; Humans; Methyl Methanesulfonate; Mutagens; Protein Interaction Maps; Quinolones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; tert-Butylhydroperoxide; Vesicular Transport Proteins

2012
Confirmation of Frm2 as a novel nitroreductase in Saccharomyces cerevisiae.
    Biochemical and biophysical research communications, 2012, Jul-13, Volume: 423, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Aminoquinolines; Amodiaquine; Chromatography, Liquid; Cloning, Molecular; Mass Spectrometry; NAD; Nitroreductases; Oxidative Stress; Quinolones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2012
Targeted expression of ornithine decarboxylase antizyme prevents upper aerodigestive tract carcinogenesis in p53-deficient mice.
    Carcinogenesis, 2013, Volume: 34, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Dimethylnitrosamine; Epithelium; Esophageal Neoplasms; Gastric Mucosa; Head and Neck Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Polyamines; Proteins; Quinolones; Tongue Neoplasms; Tumor Burden; Tumor Suppressor Protein p53

2013
Basal stem cells contribute to squamous cell carcinomas in the oral cavity.
    Carcinogenesis, 2013, Volume: 34, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; Epithelium; Lac Operon; Mice; Mice, Transgenic; Mouth; Mouth Neoplasms; Quinolones; Stem Cells; Tongue Neoplasms

2013
Effect of topical 5-ALA mediated photodynamic therapy on proliferation index of keratinocytes in 4-NQO-induced potentially malignant oral lesions.
    Journal of photochemistry and photobiology. B, Biology, 2013, Sep-05, Volume: 126

    Topics: 4-Nitroquinoline-1-oxide; Administration, Topical; Aminolevulinic Acid; Animals; Apoptosis; Cell Proliferation; Epithelium; Female; Keratinocytes; Mouth Neoplasms; Photochemotherapy; Photosensitizing Agents; Quinolones; Rats, Wistar

2013
Mutagen sensitivity as measured by induced chromatid breakage as a marker of cancer risk.
    Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1105

    Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; Cells, Cultured; Chromatids; DNA Breaks, Double-Stranded; Genetic Markers; Genetic Predisposition to Disease; Humans; Lymphocytes; Mutagens; Neoplasms; Quinolones; Radiation Injuries; Risk

2014
Systemic toxic effects during early phases of topical 4-NQO-induced oral carcinogenesis in rats.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Administration, Topical; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Chemical Analysis; Carcinogenesis; Carcinogens; Female; Keratinocytes; Kidney Tubules; Leukocyte Count; Leukoplakia, Oral; Liver; Monocytes; Pancreas; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Quinolones; Rats; Rats, Wistar; Serum Albumin; Spleen; Submandibular Gland; Tongue; Tongue Neoplasms; Weight Gain

2014
The influence of sleep restriction on expression of apoptosis regulatory proteins p53, Bcl-2 and Bax following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2015, Volume: 44, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Carcinogenesis; Carcinogens; Cell Proliferation; Epithelium; Leukoplakia, Oral; Male; Precancerous Conditions; Proto-Oncogene Proteins c-bcl-2; Quinolones; Random Allocation; Rats; Rats, Wistar; Sleep; Sleep Wake Disorders; Time Factors; Tongue Neoplasms; Tumor Suppressor Protein p53

2015
IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus.
    Oncotarget, 2014, Sep-30, Volume: 5, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; Animals; Arginase; Carcinoma, Squamous Cell; Case-Control Studies; CD11b Antigen; Cells, Cultured; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; HLA-DR Antigens; Humans; Interleukin-6; Lipopolysaccharide Receptors; Male; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; Neoplasm Staging; Phosphorylation; Quinolones; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor; Time Factors; Treatment Outcome; Tumor Burden

2014
Chemopreventive activity of systemically administered curcumin on oral cancer in the 4-nitroquinoline 1-oxide model.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Corn Oil; Curcumin; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Gene Expression; Male; Mouth Neoplasms; Quinolones; Rats; Tongue

2015
Oral and IV dosages of doxorubicin-methotrexate loaded- nanoparticles inhibit progression of oral cancer by down- regulation of matrix Methaloproteinase 2 expression in vivo.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:24

    Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Disease Progression; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Male; Matrix Metalloproteinase 2; Methotrexate; Mouth Neoplasms; Nanoparticles; Quinolones; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2014
Genotoxicity testing of 3,4,5-trimethylfuran-2(5H)-one, a compound from plant-derived smoke with germination inhibitory activity.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2015, Jan-15, Volume: 778

    Topics: 4-Nitroquinoline-1-oxide; Benzopyrenes; Cell Line, Tumor; Cell Survival; Furans; Genes, Reporter; Germination; Hepatocytes; Humans; Luciferases; Mutagenicity Tests; Mutagens; Plants; Quinolones; Salmonella typhimurium; Seeds; SOS Response, Genetics; Transcription Factors

2015
1α,25-Dihydroxyvitamin D3 Inhibits Esophageal Squamous Cell Carcinoma Progression by Reducing IL6 Signaling.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Animals; Calcitriol; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Disease Progression; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Interleukin-6; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Microscopy, Fluorescence; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Tumor Burden; Vitamins; Xenograft Model Antitumor Assays

2015
A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:7

    Topics: 4-Nitroquinoline-1-oxide; Animals; DNA Mutational Analysis; Gene Frequency; Male; Mouth; Mouth Neoplasms; Organ Specificity; Quinolones; Rats, Inbred BB; Rats, Inbred F344

2015
Mcl-1 is an important therapeutic target for oral squamous cell carcinomas.
    Oncotarget, 2015, Jun-30, Volume: 6, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy-Related Protein 5; Autophagy-Related Protein 7; bcl-X Protein; Beclin-1; Biphenyl Compounds; Carcinoma, Squamous Cell; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Female; Gossypol; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitophagy; Mouth Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proto-Oncogene Proteins; Quinolones; Random Allocation; RNA Interference; RNA, Small Interfering; Sulfonamides; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays

2015
Impact of Short-term 1,25-Dihydroxyvitamin D3 on the Chemopreventive Efficacy of Erlotinib against Oral Cancer.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Calcitriol; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Down-Regulation; Drug Administration Schedule; ErbB Receptors; Erlotinib Hydrochloride; Female; Head and Neck Neoplasms; Humans; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Mice, SCID; Mouth Neoplasms; Neoplasm Transplantation; Quinolones

2015
Gene expression profiling signatures for the diagnosis and prevention of oral cavity carcinogenesis-genome-wide analysis using RNA-seq technology.
    Oncotarget, 2015, Sep-15, Volume: 6, Issue:27

    Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle; Databases, Genetic; Esophageal Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Mice; Mice, Inbred C57BL; Mouth Neoplasms; Quinolones; Sequence Analysis, RNA; Tongue Neoplasms; Transcriptome

2015
Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.
    Mutagenesis, 2016, Volume: 31, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; DNA Damage; Epoxy Compounds; HL-60 Cells; Humans; Male; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Procarbazine; Quinolones; Resveratrol; Stilbenes

2016
Development of a 4-NQO toxic equivalency factor (TEF) approach to enable a preliminary risk assessment of unknown genotoxic compounds detected by the Ames II test in UV/H₂O₂ water treatment samples.
    Chemosphere, 2016, Volume: 144

    Topics: 4-Nitroquinoline-1-oxide; Adult; Carcinogens; DNA Damage; Humans; Hydrogen Peroxide; Mutagenicity Tests; Nitrates; Quinolones; Risk Assessment; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification

2016
Roles of coinhibitory molecules B7-H3 and B7-H4 in esophageal squamous cell carcinoma.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Animals; B7 Antigens; Carcinoma, Squamous Cell; Cell Line, Tumor; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Middle Aged; Quinolones; V-Set Domain-Containing T-Cell Activation Inhibitor 1

2016
Suppression of Rat Oral Carcinogenesis by Agonists of Peroxisome Proliferator Activated Receptor γ.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Male; Mouth Neoplasms; Pioglitazone; PPAR gamma; Quinolones; Rats; Rats, Inbred F344; Rosiglitazone; Thiazolidinediones

2015
Centrosome-Dependent Bypass of the DNA Damage Checkpoint by the Polo Kinase Cdc5.
    Cell reports, 2016, Feb-16, Volume: 14, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Cell Cycle Proteins; Centrosome; Chromatin; DNA Damage; DNA-Binding Proteins; Endonucleases; Feedback, Physiological; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Fungal; Methyl Methanesulfonate; Protein Domains; Protein Serine-Threonine Kinases; Quinolones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors

2016
The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Inbred CBA; Mouth Mucosa; Mouth Neoplasms; Quinolones

2016
Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice.
    Cellular signalling, 2016, Volume: 28, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Adhesion; Cell Movement; Extracellular Space; Fibroblasts; Fibronectins; Gene Deletion; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; HCT116 Cells; Head and Neck Neoplasms; HEK293 Cells; HeLa Cells; Humans; Inositol Phosphates; Mice, Knockout; Neoplasm Invasiveness; Phosphotransferases (Phosphate Group Acceptor); Quinolones; RNA, Small Interfering; Signal Transduction

2016
Regulatory T cells function at the early stage of tumor progression in a mouse model of tongue squamous cell carcinoma.
    Cancer immunology, immunotherapy : CII, 2016, Volume: 65, Issue:11

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cells, Cultured; Chemokine CCL17; Chemokine CCL20; Disease Models, Animal; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Interleukin-10; Lymphocyte Count; Male; Mice; Mice, Inbred C57BL; Quinolones; Receptors, CCR4; T-Lymphocytes, Regulatory; Tongue Neoplasms; Transforming Growth Factor beta

2016
p120-Catenin Is Required for Dietary Calcium Suppression of Oral Carcinogenesis in Mice.
    Journal of cellular physiology, 2017, Volume: 232, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Animals; Calcium; Calcium, Dietary; Carcinogenesis; Carcinoma, Squamous Cell; Catenins; Cell Differentiation; Cell Proliferation; Delta Catenin; Epithelium; Gene Deletion; Mice, Inbred C57BL; Mice, Knockout; Mouth Neoplasms; Neoplasm Invasiveness; Parathyroid Hormone; Phosphorus; Quinolones; Tamoxifen

2017
Vascular alterations after photodynamic therapy mediated by 5-aminolevulinic acid in oral leukoplakia.
    Lasers in medical science, 2017, Volume: 32, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Aminolevulinic Acid; Animals; Humans; Immunohistochemistry; Leukoplakia, Oral; Male; Microvessels; Mouth Mucosa; Organ Size; Photochemotherapy; Photosensitizing Agents; Quinolones; Rats, Wistar; Tongue

2017
Geraniol attenuates 4NQO-induced tongue carcinogenesis through downregulating the activation of NF-κB in rats.
    Molecular and cellular biochemistry, 2017, Volume: 434, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Acyclic Monoterpenes; Animals; Anticarcinogenic Agents; Blood Cell Count; Blotting, Western; Carcinogens; Down-Regulation; Inflammation; Inflammation Mediators; Male; NF-kappa B; Quinolones; Rats; Rats, Wistar; Terpenes; Tongue Neoplasms

2017
PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:12

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antibodies, Monoclonal; Apoptosis; Carcinogens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Progression; Female; Granzymes; Immunoglobulin G; Immunohistochemistry; Interferon-gamma; Ligands; Mice; Mice, Inbred C57BL; Mouth Neoplasms; Precancerous Conditions; Programmed Cell Death 1 Receptor; Quinolones; STAT1 Transcription Factor

2017
Proteomics-based investigation of multiple stages of OSCC development indicates that the inhibition of Trx-1 delays oral malignant transformation.
    International journal of oncology, 2018, Volume: 52, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Animals; Apoptosis; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Disulfides; Female; Humans; Imidazoles; Male; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Orthognathic Surgical Procedures; Oxidative Stress; Precancerous Conditions; Proteomics; Quinolones; Rats, Sprague-Dawley; Reactive Oxygen Species; Thioredoxins; Tongue

2018
Lack of superoxide dismutase in a rad51 mutant exacerbates genomic instability and oxidative stress-mediated cytotoxicity in Saccharomyces cerevisiae.
    Free radical biology & medicine, 2018, Volume: 129

    Topics: 4-Nitroquinoline-1-oxide; DNA Breaks, Double-Stranded; DNA, Fungal; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Homologous Recombination; Hydrogen Peroxide; Hydroxyurea; Methyl Methanesulfonate; Molecular Chaperones; Mutation; Paraquat; Phleomycins; Quinolones; Rad51 Recombinase; Reactive Oxygen Species; Recombinational DNA Repair; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Superoxide Dismutase-1

2018
Deregulation of the 19S proteasome complex increases yeast resistance to 4-NQO and oxidative stress via upregulation of Rpn4- and proteasome-dependent stress responsive genes.
    FEMS yeast research, 2019, 03-01, Volume: 19, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; DNA-Binding Proteins; Oxidants; Oxidative Stress; Proteasome Endopeptidase Complex; Quinolones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stress, Physiological; Transcription Factors; Up-Regulation

2019
PrimPol is required for the maintenance of efficient nuclear and mitochondrial DNA replication in human cells.
    Nucleic acids research, 2019, 05-07, Volume: 47, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Bleomycin; Cell Line, Transformed; Cell Line, Tumor; Cell Nucleus; Cisplatin; DNA; DNA Primase; DNA Replication; DNA-Directed DNA Polymerase; Fibroblasts; Gene Deletion; Humans; Micronuclei, Chromosome-Defective; Mitochondria; Multifunctional Enzymes; Mutagens; Osteoblasts; Quinolones; Sister Chromatid Exchange; Ultraviolet Rays

2019
Investigation of comet assays under conditions mimicking ocular instillation administration in a three-dimensional reconstructed human corneal epithelial model.
    Cutaneous and ocular toxicology, 2019, Volume: 38, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Acridine Orange; Acrylamide; Administration, Ophthalmic; Cell Line; Comet Assay; Cornea; DNA Damage; Epithelial Cells; Epithelium, Corneal; Ethidium; Humans; Hydrogen Peroxide; In Vitro Techniques; Methyl Methanesulfonate; Ophthalmic Solutions; Paraquat; Quinolones

2019
Oxidation and alkylation stresses activate ribosome-quality control.
    Nature communications, 2019, 12-09, Volume: 10, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Alkylation; DNA Adducts; DNA Damage; HEK293 Cells; Humans; Methyl Methanesulfonate; Mutation; Oxidation-Reduction; Oxidative Stress; Peptides; Polyribosomes; Protein Aggregates; Quinolones; Ribosomal Proteins; Ribosomes; RNA Stability; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination

2019
A PIK3CA transgenic mouse model with chemical carcinogen exposure mimics human oral tongue tumorigenesis.
    International journal of experimental pathology, 2020, Volume: 101, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Disease Progression; Lymphocytes; Mice, Inbred CBA; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Quinolones; Squamous Cell Carcinoma of Head and Neck; Time Factors; Tongue Neoplasms

2020
PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts.
    Nature communications, 2020, 11-17, Volume: 11, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benz(a)Anthracenes; Cell Line; DNA Adducts; DNA Primase; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Homologous Recombination; Humans; Multifunctional Enzymes; Quinolones; Rad51 Recombinase; Single Molecule Imaging; Sister Chromatid Exchange

2020
Local Anti-PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model.
    Cancer prevention research (Philadelphia, Pa.), 2021, Volume: 14, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antibodies, Monoclonal; Carcinogenesis; Disease Models, Animal; Drug Delivery Systems; Female; Genes, p53; Head and Neck Neoplasms; Humans; Immune Checkpoint Inhibitors; Injections, Intralesional; Male; Mice; Mice, Transgenic; Mouth Neoplasms; Precancerous Conditions; Programmed Cell Death 1 Receptor; Quinolones; Squamous Cell Carcinoma of Head and Neck

2021
Dual Fluorescent Protein (yEGFP/DsRed-Express-2) Bioassay System for Rapid Screening for Chemical Mutagens Based on RNR3 Regulation in Saccharomyces Cerevisiae.
    Biomedical and environmental sciences : BES, 2021, May-20, Volume: 34, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Biological Assay; Chlorambucil; Fluorouracil; Green Fluorescent Proteins; Luminescent Proteins; Methyl Methanesulfonate; Mutagenicity Tests; Mutagens; Quinolones; Ribonucleoside Diphosphate Reductase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2021
Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma.
    Cell reports. Medicine, 2021, 09-21, Volume: 2, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Amino Acid Sequence; Animals; Antigens, Neoplasm; Carcinogens; Carcinoma, Squamous Cell; CD8-Positive T-Lymphocytes; Clone Cells; Humans; Immune Checkpoint Inhibitors; Lymphocyte Count; Lymphocyte Depletion; Mice, Inbred C57BL; Mouth Neoplasms; Neoplasm Invasiveness; Peptides; Quinolones; T-Lymphocytes, Regulatory

2021
Molecular immuno-imaging improves tumor detection in head and neck cancer.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Cell Line, Tumor; Female; Head and Neck Neoplasms; Magnetic Resonance Imaging; Mice; Molecular Imaging; Neoplasms, Experimental; Quinolones

2022
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 01-18, Volume: 119, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Antineoplastic Agents; Carcinogens; Cell Line, Tumor; Dendritic Cells; Epithelial Cells; Epithelium; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histones; Humans; Immunity; Langerhans Cells; Phagocytes; Quinolones; Squamous Cell Carcinoma of Head and Neck; T-Lymphocytes, Regulatory; Tongue; Transcriptome

2022
Generation and Application of Inducible Chimeric RNA
    Cells, 2022, 01-14, Volume: 11, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Body Weight; Carcinogens; Disease Models, Animal; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Knock-In Techniques; Genotype; Mice; Mice, Inbred C57BL; Mouse Embryonic Stem Cells; Quinolones; RNA, Antisense; Tamoxifen

2022