4-nitrophenol and phenobarbital

4-nitrophenol has been researched along with phenobarbital in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's8 (32.00)18.2507
2000's9 (36.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dunn, WJ; Grigoras, S; Koehler, MG1
Strassburg, CP; Tukey, RH1
Caron, G; Ermondi, G1
Carrupt, PA; Martel, S; Ottaviani, G2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Del Villar, E; Gaule, C; Sanchez, E; Vega, P1
Bement, WJ; Guzelian, PS; Lambrecht, LK; McCaffrey, J; Park, SS; Schenkman, JB; Sinclair, JF; Sinclair, PR; Smith, EL; Wood, SG1
Hanioka, N; Hoshikawa, Y; Mitsui, T; Oguri, K; Yoshimura, H1
Malejka-Giganti, D; Ryzewski, CN1
Lech, JJ; Vodicnik, MJ; Weitman, SD1
Matsui, M; Watanabe, HK2
Hirata, M; Tonda, K1
Belinsky, SA; Evans, RK; Kauffman, FC; Reinke, LA; Thurman, RG1
Castell, JV; Donato, MT; Gómez-Lechón, MJ1
Hattori, T; Hayashi, Y; Horio, F; Machino, S; Makino, S; Shibata, T; Yoshida, A1
Conney, AH; Huang, MT; Suchar, LA; Zhu, BT1
Konishi, H; Morita, K; Yamaji, A1
Mazur, SP1
Kuhn, UD; Müller, D; Rost, M1
Hyun, SH; Jeon, TW; Jeong, HG; Jeong, TC; Jin, CH; Kim, DO; Kim, EJ; Kim, JA; Lee, BM; Lee, ES; Lee, SK; Moon, GI1
Draper, A; Leonard, N; Ogilvie, BW; Parkinson, A1
Batt, AM; Boutin, JA; Jacquier, A; Marlière, P; Siest, G1

Reviews

1 review(s) available for 4-nitrophenol and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

24 other study(ies) available for 4-nitrophenol and phenobarbital

ArticleYear
The role of solvent-accessible surface area in determining partition coefficients.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:7

    Topics: Diffusion; Solubility; Solvents; Structure-Activity Relationship

1987
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
    Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13

    Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water

2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
Drug metabolism in Octodon degus: low inductive effect of phenobarbital.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1990, Volume: 96, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronates; Glucuronosyltransferase; Hydroxylation; Male; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Rodentia; Steroid Hydroxylases

1990
Ethanol increases cytochromes P450IIE, IIB1/2, and IIIA in cultured rat hepatocytes.
    Archives of biochemistry and biophysics, 1991, Feb-01, Volume: 284, Issue:2

    Topics: Acetaminophen; Animals; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dexamethasone; Ethanol; Hydroxylation; Liver; Male; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Troleandomycin

1991
Species difference in codeine uridine diphosphate-glucuronyltransferase activity of liver microsomes.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:11

    Topics: Animals; Biphenyl Compounds; Codeine; Enzyme Induction; Glucuronosyltransferase; Guinea Pigs; In Vitro Techniques; Male; Methylcholanthrene; Mice; Microsomes, Liver; Morphine; Nitrophenols; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Substrate Specificity

1990
Microsomal metabolism of the carcinogen, N-2-fluorenyl-acetamide, by the mammary gland and liver of female rats. II. Glucuronidation of ring- and N-hydroxylated metabolites of N-2-fluorenylacetamide.
    Carcinogenesis, 1985, Volume: 6, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; beta-Naphthoflavone; Carbon Radioisotopes; Female; Glucuronates; Glucuronosyltransferase; Hydroxylation; In Vitro Techniques; Lactation; Mammary Glands, Animal; Microsomes; Microsomes, Liver; Nitrophenols; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains

1985
Influence of pregnancy on the hepatic metabolism of parathion.
    Developmental pharmacology and therapeutics, 1986, Volume: 9, Issue:1

    Topics: Animals; Female; Gestational Age; In Vitro Techniques; Liver; Mice; Mice, Inbred ICR; Nitrophenols; Paraoxon; Parathion; Perfusion; Phenobarbital; Pregnancy; Pregnancy, Animal

1986
Effects of steroid hormones and xenobiotics on the pubertal development of UDP-glucuronosyltransferase activities towards androsterone and 4-nitrophenol in Wistar rats.
    The Biochemical journal, 1984, Sep-01, Volume: 222, Issue:2

    Topics: Androsterone; Animals; Corticosterone; Estradiol; Female; Glucuronosyltransferase; Gonadal Steroid Hormones; Liver; Male; Methylcholanthrene; Milk; Nitrophenols; Phenobarbital; Phenotype; Rats; Rats, Inbred Strains; Sexual Maturation

1984
Rat liver sulfotransferases: effects of gonadal hormones and other factors on enzyme activities.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:9

    Topics: Aging; Androsterone; Animals; Body Weight; Corticosterone; Cytosol; Estradiol; Gonadal Steroid Hormones; Liver; Male; Methylcholanthrene; Nitrophenols; Organ Size; Phenobarbital; Progesterone; Rats; Rats, Inbred Strains; Sulfurtransferases; Testosterone

1984
Glucuronidation and sulfation of p-nitrophenol in isolated rat hepatocyte subpopulations. Effects of phenobarbital and 3-methylcholanthrene pretreatment.
    Chemico-biological interactions, 1983, Volume: 47, Issue:3

    Topics: 4-Aminobenzoic Acid; Animals; Cytochrome P-450 Enzyme System; Glucuronates; In Vitro Techniques; Liver; Male; Methylcholanthrene; Nitrobenzenes; Nitrophenols; Phenobarbital; Rats; Rats, Inbred Strains; Sulfates

1983
Conjugation of p-nitrophenol in the perfused rat liver: the effect of substrate concentration and carbohydrate reserves.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Animals; Antimetabolites; Carbohydrate Metabolism; Fasting; Female; Flavoproteins; Glucuronosyltransferase; Liver; NAD; Nitroanisole O-Demethylase; Nitrophenols; Phenobarbital; Rats; Sulfates; Sulfurtransferases

1981
Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Adult; Aged; Cells, Cultured; Clofibric Acid; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Ethanol; Female; Humans; Isoenzymes; Liver; Male; Methylcholanthrene; Middle Aged; Nitrophenols; Oxazines; Oxidation-Reduction; Phenobarbital; Safrole; Substrate Specificity; Testosterone

1995
UDP glucuronosyltransferase gene expression is involved in the stimulation of ascorbic acid biosynthesis by xenobiotics in rats.
    The Journal of nutrition, 1993, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animals; Ascorbic Acid; Base Sequence; Blotting, Northern; Body Weight; Chloramphenicol; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Injections, Intraperitoneal; Liver; Methylcholanthrene; Molecular Sequence Data; Nitrophenols; Organ Size; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Gunn; Rats, Inbred Strains; RNA, Messenger; Time Factors; Xenobiotics

1993
Similarities and differences in the glucuronidation of estradiol and estrone by UDP-glucuronosyltransferase in liver microsomes from male and female rats.
    Biochemical pharmacology, 1996, May-03, Volume: 51, Issue:9

    Topics: Animals; Dexamethasone; Estradiol; Estrone; Female; Glucuronates; Glucuronosyltransferase; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Nitrophenols; Phenobarbital; Rats; Substrate Specificity; Testosterone

1996
Involvement of CYP2E in 8-hydroxylation of theophylline in mouse hepatic microsomes-difference from its N-demethylations.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:4

    Topics: Acetone; Aminoacetonitrile; Aminopyrine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fomepizole; Hydroxylation; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Nitrophenols; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Theophylline

1996
Sex differences in biotransformation of the xenobiotic p-nitroanisole in isolated rat hepatocyte under the influence of phenobarbital.
    Biochemistry. Biokhimiia, 1997, Volume: 62, Issue:4

    Topics: Animals; Anisoles; Biotransformation; Cells, Cultured; Cytochrome P-450 Enzyme System; Female; Liver; Male; Nitrophenols; Phenobarbital; Rats; Rats, Wistar; Sex Characteristics; Xenobiotics

1997
Para-nitrophenol glucuronidation and sulfation in rat and human liver slices.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2001, Volume: 53, Issue:1

    Topics: Animals; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Glucuronates; Humans; In Vitro Techniques; Liver; Male; Nitrophenols; Phenobarbital; Rats; Rats, Wistar; Species Specificity; Sulfates; Time Factors

2001
Role of metabolism in parathion-induced hepatotoxicity and immunotoxicity.
    Journal of toxicology and environmental health. Part A, 2005, Dec-10, Volume: 68, Issue:23-24

    Topics: Alanine Transaminase; Animals; Antibody-Producing Cells; Aspartate Aminotransferases; Biotransformation; Cytochrome P-450 CYP2B1; Female; Glutathione; Insecticides; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Nitrophenols; Paraoxon; Parathion; Phenobarbital; Rats; Rats, Sprague-Dawley; Sheep; Spleen

2005
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
    Drug metabolism reviews, 2006, Volume: 38, Issue:1-2

    Topics: Animals; Benzodiazepines; Blotting, Western; Body Weight; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diazepam; Hypnotics and Sedatives; Immunohistochemistry; Isoenzymes; Lauric Acids; Liver Neoplasms; Male; Mice; Microsomes, Liver; Nitrophenols; Organ Size; Oxazepam; Phenobarbital; Rats; Rats, Sprague-Dawley

2006
UDP-glucuronosyltransferase activities in human liver microsomes and in some laboratory animal species.
    Biochemical pharmacology, 1981, Sep-01, Volume: 30, Issue:17

    Topics: Adolescent; Aged; Animals; Camphanes; Chloramphenicol; Eugenol; Female; Glucuronides; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Middle Aged; Nitrophenols; Phenobarbital; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Swine; Uridine Diphosphate

1981