Page last updated: 2024-09-05

4-n-butylresorcinol and kojic acid

4-n-butylresorcinol has been researched along with kojic acid in 6 studies

Compound Research Comparison

Studies
(4-n-butylresorcinol)
Trials
(4-n-butylresorcinol)
Recent Studies (post-2010)
(4-n-butylresorcinol)
Studies
(kojic acid)
Trials
(kojic acid)
Recent Studies (post-2010) (kojic acid)
2371964610369

Protein Interaction Comparison

ProteinTaxonomy4-n-butylresorcinol (IC50)kojic acid (IC50)
Polyphenol oxidase 2Agaricus bisporus9.2
D-amino-acid oxidaseSus scrofa (pig)2
TyrosinaseHomo sapiens (human)8.275
D-amino-acid oxidaseHomo sapiens (human)2
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)2
Alpha-1B adrenergic receptorHomo sapiens (human)8.33
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Baek, HS; Hong, YD; Joo, YH; Lee, CS; Park, YH; Rho, HS; Shin, SS1
Jung, SH; Manickam, M; Namasivayam, V; Pillaiyar, T1
Haudecoeur, R; Pérès, B; Roulier, B1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Ahlheit, S; Batzer, J; Gerwat, W; Kolbe, L; Mann, T; Scherner, C; Stäb, F; Wenck, H1
Chen, Q; Conney, AH; Du, Z; Jiang, Y; Lu, Y; Xue, G; Zhang, K; Zheng, X1

Reviews

2 review(s) available for 4-n-butylresorcinol and kojic acid

ArticleYear
Inhibitors of Melanogenesis: An Updated Review.
    Journal of medicinal chemistry, 2018, 09-13, Volume: 61, Issue:17

    Topics: alpha-MSH; Biphenyl Compounds; Crystallization; Enzyme Inhibitors; Humans; Melanins; Monophenol Monooxygenase; Peptidomimetics; Radiation, Ionizing; Resveratrol; Signal Transduction; Skin

2018
Advances in the Design of Genuine Human Tyrosinase Inhibitors for Targeting Melanogenesis and Related Pigmentations.
    Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22

    Topics: Agaricales; Amino Acid Sequence; Biological Factors; Drug Delivery Systems; Drug Design; Enzyme Inhibitors; Humans; Melanins; Melanocytes; Melanoma; Monophenol Monooxygenase; Pigmentation; Protein Structure, Secondary; Skin Lightening Preparations

2020

Trials

1 trial(s) available for 4-n-butylresorcinol and kojic acid

ArticleYear
4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27 Suppl 1

    Topics: Administration, Topical; Aged; Arbutin; Female; Humans; Hydroquinones; Hyperpigmentation; Melanins; Middle Aged; Monophenol Monooxygenase; Pyrones; Resorcinols; Single-Blind Method; Skin; Skin Lightening Preparations; Tissue Culture Techniques; Treatment Outcome

2013

Other Studies

3 other study(ies) available for 4-n-butylresorcinol and kojic acid

ArticleYear
Adamantyl N-benzylbenzamide: new series of depigmentation agents with tyrosinase inhibitory activity.
    Bioorganic & medicinal chemistry letters, 2012, Mar-01, Volume: 22, Issue:5

    Topics: Adamantane; Agaricales; Animals; Benzamides; Cell Line, Tumor; Melanins; Melanocytes; Mice; Models, Molecular; Monophenol Monooxygenase; Skin Pigmentation

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Synthesis and biological evaluation of unsymmetrical curcumin analogues as tyrosinase inhibitors.
    Molecules (Basel, Switzerland), 2013, Apr-03, Volume: 18, Issue:4

    Topics: Animals; Curcumin; Female; Inhibitory Concentration 50; Kinetics; Male; Mice; Mice, Inbred Strains; Monophenol Monooxygenase; Polyphenols; Pyrones; Resorcinols; Toxicity Tests, Acute

2013