4-methylumbelliferyl glucuronide has been researched along with 4-methylumbelliferyl sulfate in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leboeuf, E; Pang, KS; Ratna, S; Zimmerman, CL | 1 |
| de Wolff, FA; Edelbroek, PM; Hessing, TJ; van Kempen, GM | 1 |
| Hanano, M; Morita, K; Sugiyama, Y | 1 |
| Brouwer, S; Mulder, GJ; Pang, KS; Scholtens, E; Weitering, JG | 1 |
| Femfert, U; Kuntz, HD; May, B | 1 |
| Garrett, ER; Venitz, J | 1 |
| Bandyopadhyay, L; Chiba, M; Pang, KS; Ratna, S | 1 |
| Chen, J; Pang, KS | 1 |
| Higaki, K; Kimura, T; Nishida, C; Ogawara, KI | 1 |
| Brouwer, KL; Hoffmaster, KA; Humphreys, JE; Nezasa, K; Tian, X; Zamek-Gliszczynski, MJ | 1 |
| Albouy-Llaty, M; Barrier, L; Brunet, B; Carato, P; Condylis, M; Dupuis, A; Grignon, C; Migeot, V; Venisse, N | 1 |
11 other study(ies) available for 4-methylumbelliferyl glucuronide and 4-methylumbelliferyl sulfate
| Article | Year |
|---|---|
High-performance liquid chromatographic method for the direct determination of 4-methylumbelliferone and its glucuronide and sulfate conjugates. Application to studies in the single-pass in situ perfused rat intestine-liver preparation.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Erythrocytes; Humans; Hymecromone; Intestines; Liver; Perfusion; Rats | 1991 |
Analysis of phenprocoumon and its hydroxylated and conjugated metabolites in human urine by high-performance liquid chromatography after solid-phase extraction.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Glucuronidase; Humans; Hydrolysis; Hymecromone; Indicators and Reagents; Male; Middle Aged; Phenprocoumon; Spectrophotometry, Ultraviolet; Sulfatases | 1990 |
Pharmacokinetic study of 4-methylumbelliferone in rats: influence of dose on its first-pass hepatic elimination.
Topics: Animals; Biological Availability; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Femoral Vein; Hymecromone; Injections, Intravenous; Kinetics; Liver; Male; Portal Vein; Protein Binding; Rats; Rats, Inbred Strains; Time Factors; Umbelliferones | 1986 |
Glucuronidation and sulfation in the rat in vivo. The role of the liver and the intestine in the in vivo clearance of 4-methylumbelliferone.
Topics: Animals; Blood Proteins; Hymecromone; Infusions, Parenteral; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Protein Binding; Rats; Rats, Inbred Strains; Umbelliferones | 1985 |
Rapid high-performance liquid chromatographic method for the measurement of hymecromon and its conjugates in blood plasma or serum at concentrations attained during therapy.
Topics: Chromatography, High Pressure Liquid; Humans; Hymecromone; Kinetics; Umbelliferones | 1983 |
Comparisons of detections, stabilities, and kinetics of degradation of hymecromone and its glucuronide and sulfate metabolites.
Topics: Drug Stability; Hymecromone; Solubility | 1994 |
Futile cycling between 4-methylumbelliferone and its conjugates in perfused rat liver.
Topics: Animals; Bile; Blood Proteins; Hymecromone; Liver; Male; Models, Biological; Perfusion; Protein Binding; Rats; Rats, Sprague-Dawley | 1993 |
Effect of flow on first-pass metabolism of drugs: single pass studies on 4-methylumbelliferone conjugation in the serially perfused rat intestine and liver preparations.
Topics: Animals; Hymecromone; Intestinal Mucosa; Liver; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1997 |
Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics. III: mechanisms for sinusoidal efflux of 4-methylumbelliferone sulfate.
Topics: Animals; Biological Transport, Active; Chlorides; Glucuronides; Glutathione; Hymecromone; In Vitro Techniques; Liver; Male; Models, Biological; Rats; Rats, Wistar; Sodium Azide; Sulfates; Xenobiotics | 2004 |
Differential involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in biliary excretion of 4-methylumbelliferyl glucuronide and sulfate in the rat.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Cell Line; Dogs; Hymecromone; Male; Rats; Rats, Wistar | 2006 |
Validation of a probe for assessing deconjugation of glucuronide and sulfate phase II metabolites assayed through LC-MS/MS in biological matrices.
Topics: Chromatography, Liquid; Drug Monitoring; Glucuronides; Humans; Hymecromone; Limit of Detection; Linear Models; Reproducibility of Results; Sulfates; Tandem Mass Spectrometry | 2017 |