Compounds > 4-methylumbelliferyl acetate

4-methylumbelliferyl acetate and irinotecan

4-methylumbelliferyl acetate has been researched along with irinotecan in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Mazzolari, A; Pedretti, A; Testa, B; Vistoli, G1
Bosron, WF; Cummings, OW; Davis, WI; Fredenburg, TB; Murry, DJ; Quinney, SK; Sanghani, SP; Seitz, DE; Sun, Z1
Kim, SR; Kubo, T; Matsumoto, K; Minami, H; Nakajima, T; Ohno, Y; Ohtsu, A; Ozawa, S; Sai, K; Saijo, N; Saito, H; Saito, Y; Sawada, J; Shirao, K; Yamamoto, N; Yoshida, T1
Igawa, Y; Imai, T; Kasahara, A; Kubota, K; Matsumoto, K; Ohura, K; Tanaka, M; Uno, Y; Wada, N1

Other Studies

4 other study(ies) available for 4-methylumbelliferyl acetate and irinotecan

ArticleYear
In silico prediction of human carboxylesterase-1 (hCES1) metabolism combining docking analyses and MD simulations.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Carboxylic Ester Hydrolases; Catalytic Domain; Computer Simulation; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Substrate Specificity

2010
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Oct-15, Volume: 9, Issue:13

    Topics: Blotting, Northern; Blotting, Western; Brain; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Colon; Colonic Neoplasms; DNA Topoisomerases, Type I; Electrophoresis, Polyacrylamide Gel; Female; Humans; Hydrolases; Hydrolysis; Irinotecan; Liver; Male; Reverse Transcriptase Polymerase Chain Reaction; RNA; Umbelliferones

2003
Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2).
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:10

    Topics: Animals; Asian People; Camptothecin; Carboxylesterase; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Humans; Irinotecan; Nitrophenols; Polymorphism, Single Nucleotide; RNA Splicing; Umbelliferones

2005
Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys.
    Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line; HEK293 Cells; Humans; Hydrolysis; Intestine, Small; Irinotecan; Isoenzymes; Macaca fascicularis; Microsomes; Umbelliferones

2020