4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside has been researched along with hymecromone in 22 studies
| Studies (4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside) | Trials (4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside) | Recent Studies (post-2010) (4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside) | Studies (hymecromone) | Trials (hymecromone) | Recent Studies (post-2010) (hymecromone) |
|---|---|---|---|---|---|
| 22 | 0 | 2 | 1,241 | 18 | 323 |
| Protein | Taxonomy | 4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside (IC50) | hymecromone (IC50) |
|---|---|---|---|
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Bobrow, M; Ellis, IH; Fensom, AH; Landels, EC | 1 |
| Archibald, A; Callahan, JW; Clarke, JT; Shuman, C; Skomorowski, MA | 1 |
| Desnick, RJ; Inui, K; Okada, S; Wenger, DA; Yabuuchi, H; Yutaka, T | 1 |
| Grebner, EE; Wenger, DA | 1 |
| Eto, Y; Gomibuchi, I; Ida, H; Maekawa, K; Ohashi, T; Umezawa, F | 1 |
| Besley, GT; Broadhead, DM; Young, JA | 1 |
| Beccari, T; Emiliani, C; Hosseini, R; Orlacchio, A; Stirling, JL | 1 |
| Beccari, T; Orlacchio, A; Stirling, JL | 1 |
| Charrow, J; Inui, K; Wenger, DA | 1 |
| Furukawa, M; Inui, K; Okada, S; Suehara, N; Tanizawa, O; Wenger, DA; Yabuuchi, H; Yutaka, Y | 1 |
| Inui, K; Wenger, DA | 1 |
| Bayleran, J; Hechtman, P; Saray, W | 1 |
| Jendoubi, M; Lacorazza, HD | 1 |
| Goldman, B; Peleg, L | 1 |
| Cao, Z; Petroulakis, E; Salo, T; Triggs-Raine, B | 1 |
| Bukovac, S; Callahan, J; Mahuran, D; Sharma, R | 1 |
| Galetin, A; Gardner-Stephen, D; Guo, XH; Houston, JB; Mackenzie, PI; Miners, JO; Uchaipichat, V | 1 |
| Brouxhon, SM; Federoff, HJ; Kyrkanides, S; Miller, JH; Olschowka, JA | 1 |
| Black, GW; Charnock, SJ; Davies, GJ; Macauley, MS; Robinson, CE; Sheldon, WL; Taylor, EJ; Vocadlo, DJ | 1 |
| Guetta, E; Peleg, L | 1 |
| Ambroise, C; Berger, Z; Calabrese, M; Hirst, WD; Noell, S; Oborski, C; Perkins, S; Riddell, D | 1 |
| Bergsma, AJ; Broeders, M; de Faria, DOS; Hoogeveen-Westerveld, M; Niño, MY; Pijnappel, WWMP; van den Hout, HJM; van der Beek, NAME; van der Ploeg, AT; Verheijen, FW; Wijgerde, M | 1 |
22 other study(ies) available for 4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-glucopyranoside and hymecromone
| Article | Year |
|---|---|
Tay-Sachs disease heterozygote detection: use of a centrifugal analyser for automation of hexosaminidase assays with two different artificial substrates.
Topics: Acetylglucosamine; Automation; beta-N-Acetylhexosaminidases; Cell Separation; Centrifugation; Female; Flow Cytometry; Genetic Carrier Screening; Genetic Testing; Glucosamine; Hexosaminidase A; Hot Temperature; Humans; Hymecromone; Leukocytes; Pregnancy; Prenatal Diagnosis; Tay-Sachs Disease | 1991 |
First trimester prenatal diagnosis of Tay-Sachs disease using the sulfated synthetic substrate for hexosaminidase A.
Topics: beta-N-Acetylhexosaminidases; Cells, Cultured; Chorionic Villi; Female; Hexosaminidase A; Humans; Hymecromone; Pregnancy; Pregnancy Trimester, First; Prenatal Diagnosis; Risk Factors; Substrate Specificity; Tay-Sachs Disease | 1990 |
Hexosaminidase A activity in skin fibroblasts from various types of GM2 gangliosidosis using a fluorogenic sulphated substrate.
Topics: beta-N-Acetylhexosaminidases; Catalysis; Cell Line; Fibroblasts; G(M2) Ganglioside; Gangliosidoses; Hexosaminidase A; Humans; Hymecromone; Skin | 1985 |
Use of 4-methylumbelliferyl-6-sulpho-2-acetamido-2-deoxy-beta- D-glucopyranoside for prenatal diagnosis of Tay-Sachs disease using chorionic villi.
Topics: beta-N-Acetylhexosaminidases; Chorionic Villi; Female; Hexosaminidase A; Humans; Hymecromone; Pregnancy; Prenatal Diagnosis; Tay-Sachs Disease; Umbelliferones | 1987 |
Partial deficiency of beta-hexosaminidase activity in canine GM2-gangliosidosis.
Topics: Animals; beta-N-Acetylhexosaminidases; Chromatography, DEAE-Cellulose; Disease Models, Animal; Dog Diseases; Dogs; G(M2) Ganglioside; Gangliosidoses; Hexosaminidase A; Hymecromone; Isoenzymes | 1987 |
GM2-gangliosidosis variant with altered substrate specificity: evidence for alpha-locus genetic compound.
Topics: beta-N-Acetylhexosaminidases; Humans; Hymecromone; Infant; Male; Substrate Specificity; Tay-Sachs Disease | 1987 |
Intermediate forms of human beta-N-acetylhexosaminidase lack activity towards 4-methylumbelliferyl beta-N-acetylglucosaminide 6-sulphate.
Topics: beta-N-Acetylhexosaminidases; Chromatography, DEAE-Cellulose; Female; Humans; Hymecromone; Isoenzymes; Leukemia, Lymphoid; Lymphocytes; Placenta; Pregnancy; Umbelliferones | 1987 |
Identification of beta-N-acetylhexosaminidase A in mouse tissues with the fluorigenic substrate 4-methylumbelliferyl-beta-N-acetylglucosamine 6-sulphate.
Topics: Animals; beta-N-Acetylhexosaminidases; Brain; Chromatography, DEAE-Cellulose; Hymecromone; Kidney; Liver; Male; Mice; Mice, Inbred BALB C; Spleen; Testis; Tissue Distribution; Umbelliferones | 1988 |
Late onset GM2 gangliosidosis: an alpha-locus genetic compound with near normal hexosaminidase activity.
Topics: Acetylglucosamine; Alleles; beta-N-Acetylhexosaminidases; Child, Preschool; Female; Glucosamine; Heterozygote; Hexosaminidase A; Hexosaminidases; Humans; Hymecromone; Mutation; Pedigree; Substrate Specificity; Tay-Sachs Disease | 1985 |
Prenatal diagnosis of GM2 gangliosidoses using a fluorogenic sulfated substrate.
Topics: Amniotic Fluid; Female; Hexosaminidases; Humans; Hymecromone; Pregnancy; Prenatal Diagnosis; Sandhoff Disease; Tay-Sachs Disease; Umbelliferones | 1986 |
Usefulness of 4-methylumbelliferyl-6-sulfo-2-acetamido-2-deoxy-beta-D-glucopyrano sid e for the diagnosis of GM2 gangliosidoses in leukocytes.
Topics: Acetylglucosaminidase; beta-N-Acetylhexosaminidases; Female; Genetic Carrier Screening; Hexosaminidase A; Hexosaminidases; Humans; Hymecromone; Leukocytes; Male; Sandhoff Disease; Substrate Specificity; Tay-Sachs Disease; Umbelliferones | 1984 |
Synthesis of 4-methylumbelliferyl-beta-D-N-acetylglucosamine-6-sulfate and its use in classification of GM2 gangliosidosis genotypes.
Topics: beta-N-Acetylhexosaminidases; Cell Line; Drug Stability; Fibroblasts; Gangliosidoses; Genetic Carrier Screening; Genotype; Hexosaminidase A; Hexosaminidase B; Hexosaminidases; Homozygote; Hot Temperature; Humans; Hymecromone; Kinetics; Liver; Substrate Specificity; Tay-Sachs Disease; Umbelliferones | 1984 |
In situ assessment of beta-hexosaminidase activity.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; Cells, Cultured; Fibroblasts; Glucuronates; Histocytochemistry; Humans; Hymecromone; Isoenzymes; Mutation; Naphthols; Sandhoff Disease; Spectrometry, Fluorescence; Tay-Sachs Disease | 1995 |
Detection of Tay-Sachs disease carriers among individuals with thermolabile hexosaminidase B.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; Chromatography, Ion Exchange; Enzyme Stability; Genetic Carrier Screening; Genetic Testing; Genotype; Hexosaminidase A; Hexosaminidase B; Hot Temperature; Humans; Hymecromone; Jews; Substrate Specificity; Tay-Sachs Disease | 1994 |
Benign HEXA mutations, C739T(R247W) and C745T(R249W), cause beta-hexosaminidase A pseudodeficiency by reducing the alpha-subunit protein levels.
Topics: Adult; Age of Onset; Animals; beta-N-Acetylhexosaminidases; Child; COS Cells; Gangliosidosis, GM1; Hexosaminidase A; Humans; Hymecromone; Infant; Isoenzymes; Kinetics; Macromolecular Substances; Point Mutation; Recombinant Proteins; Transfection | 1997 |
A single site in human beta-hexosaminidase A binds both 6-sulfate-groups on hexosamines and the sialic acid moiety of GM2 ganglioside.
Topics: beta-N-Acetylhexosaminidases; Binding Sites; Detergents; G(M2) Ganglioside; Hexosamines; Hexosaminidase A; Hexosaminidase B; Humans; Hymecromone; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; N-Acetylneuraminic Acid; Substrate Specificity; Sulfates | 2003 |
Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid.
Topics: Acetone; Animals; Blotting, Western; Caco-2 Cells; Diclofenac; Dimethyl Sulfoxide; Ethanol; Glucuronates; Glucuronosyltransferase; Humans; Hymecromone; Isoenzymes; Kinetics; Methanol; Mice; Probenecid; Solvents | 2004 |
beta-hexosaminidase lentiviral vectors: transfer into the CNS via systemic administration.
Topics: Animals; Animals, Newborn; Behavior, Animal; beta-N-Acetylhexosaminidases; Cell Count; Cell Line; Central Nervous System; Cricetinae; Fibroblasts; G(M2) Ganglioside; Galactosides; Gene Expression Regulation; Genetic Vectors; Glial Fibrillary Acidic Protein; Hexosaminidase B; Histocompatibility Antigens Class II; Histocytochemistry; Humans; Hymecromone; Immunodeficiency Virus, Feline; Indoles; Lentivirus; Lentivirus Infections; Mice; Mice, Knockout; Peripheral Nerves; Reverse Transcriptase Polymerase Chain Reaction; Rotation; Transduction, Genetic | 2005 |
Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a beta-N-acetylglucosaminidase and not a hyaluronidase.
Topics: Acetylglucosamine; Acetylglucosaminidase; Amino Acid Sequence; Animals; beta-N-Acetylhexosaminidases; Catalysis; Chlorocebus aethiops; COS Cells; Escherichia coli; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Hydrolysis; Hymecromone; Kinetics; Molecular Sequence Data; Multienzyme Complexes; Nuclear Magnetic Resonance, Biomolecular; Sequence Homology, Amino Acid; Streptococcus pyogenes; Structure-Activity Relationship; Substrate Specificity; Thiazoles | 2006 |
Rapid detection of fetal Mendelian disorders: Tay-Sachs disease.
Topics: Acetylglucosamine; Amniocentesis; Amniotic Fluid; beta-Hexosaminidase alpha Chain; Biological Assay; Chorionic Villi; Chorionic Villi Sampling; DNA Mutational Analysis; Female; Fetal Blood; Gene Expression Regulation, Developmental; Genetic Testing; Humans; Hymecromone; Mutation; Polymerase Chain Reaction; Predictive Value of Tests; Pregnancy; Prenatal Diagnosis; Reproducibility of Results; Substrate Specificity; Tay-Sachs Disease; Time Factors | 2008 |
Tool compounds robustly increase turnover of an artificial substrate by glucocerebrosidase in human brain lysates.
Topics: Animals; Brain; Cell-Free System; Glucosylceramidase; Glycosylation; Humans; Hymecromone; Mice | 2015 |
Enzymatic diagnosis of Pompe disease: lessons from 28 years of experience.
Topics: alpha-Glucosidases; Cells, Cultured; Clinical Enzyme Tests; Dried Blood Spot Testing; Fibroblasts; Genetic Testing; Glycogen Storage Disease Type II; Humans; Hymecromone; Leukocytes; Mutation | 2021 |