Page last updated: 2024-09-04

4-methylthioamphetamine and n-methyl-3,4-methylenedioxyamphetamine

4-methylthioamphetamine has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 12 studies

Compound Research Comparison

Studies
(4-methylthioamphetamine)
Trials
(4-methylthioamphetamine)
Recent Studies (post-2010)
(4-methylthioamphetamine)
Studies
(n-methyl-3,4-methylenedioxyamphetamine)
Trials
(n-methyl-3,4-methylenedioxyamphetamine)
Recent Studies (post-2010) (n-methyl-3,4-methylenedioxyamphetamine)
38094,2762111,392

Protein Interaction Comparison

ProteinTaxonomy4-methylthioamphetamine (IC50)n-methyl-3,4-methylenedioxyamphetamine (IC50)
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.9351
Sodium-dependent serotonin transporterHomo sapiens (human)1.1761
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)1.06
Sodium-dependent dopamine transporter Homo sapiens (human)1.7609

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, SG; Cloonan, SM; Corrigan, D; Jørgensen, AM; Keating, JJ; Knox, AJ; Lloyd, DG; Meegan, MJ; Peters, GH; Rai, D; Williams, DC1
Cloonan, SM; Corrigan, D; Kavanagh, PV; Keating, JJ; Meegan, MJ; O'Brien, JE; Williams, DC1
Butler, SG; Cloonan, SM; Keating, JJ; Knox, AJ; McNamara, YM; Meegan, MJ; Peters, GH; Williams, DC1
Elliott, SP1
Baird, AW; Cannon, DM; Flynn, JJ; Guiry, PJ; Keenan, AK; McBean, GJ; McCormack, P; Murphy, J1
Ceglia, I; Gobbi, M; Mennini, T; Moia, M; Pirona, L; Reyes-Parada, M; Scorza, C1
Guiry, PJ; Keenan, AK; McBean, GJ; Quinn, ST; Schwab, T1
Bastos, ML; Carvalho, F; Custódio, JB; Fernandes, E; Fernandes, MA; Gonçalves, DI; Moreno, AJ; Santos, MS; Vicente, JA1
Nichols, D1
Carmo, H; Dias da Silva, D; Silva, E1
Carmo, H; da Silva, DD; Silva, E1
Aoki, Y; Ishiba, A; Kato, H; Maeno, Y; Matsumoto, T; Monma-Ohtaki, J; Nagao, M; Seko-Nakamura, Y1

Other Studies

12 other study(ies) available for 4-methylthioamphetamine and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:12

    Topics: Amphetamines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Phenethylamines; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Sulfur

2009
Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.
    Bioorganic & medicinal chemistry, 2010, Jun-01, Volume: 18, Issue:11

    Topics: Amphetamines; Cell Line; Cell Line, Tumor; Cells, Cultured; Humans; Methamphetamine; Neurons; Phenethylamines; Sulfur

2010
Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
    Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3

    Topics: Alkenes; Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Molecular Structure; Nitro Compounds; Serotonin; Serotonin Plasma Membrane Transport Proteins

2011
Analysis of 4-methylthioamphetamine in clinical specimens.
    Annals of clinical biochemistry, 2001, Volume: 38, Issue:Pt 4

    Topics: Amphetamines; Animals; Chromatography, High Pressure Liquid; Hallucinogens; Humans; Indicators and Reagents; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Spectrophotometry, Ultraviolet; Substance-Related Disorders

2001
In vitro neuronal and vascular responses to 5-hydroxytryptamine: modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine.
    European journal of pharmacology, 2002, May-24, Volume: 444, Issue:1-2

    Topics: Amphetamines; Animals; Brain; Muscle, Smooth, Vascular; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptosomes

2002
p-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro.
    Journal of neurochemistry, 2002, Volume: 82, Issue:6

    Topics: Amphetamines; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Citalopram; Dose-Response Relationship, Drug; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Nerve Tissue Proteins; p-Chloroamphetamine; Piperazines; Rats; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tritium

2002
Blockade of noradrenaline transport abolishes 4-methylthioamphetamine-induced contraction of the rat aorta in vitro.
    Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amphetamines; Animals; Aorta, Thoracic; Biological Transport; Brain; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Wistar; Synaptosomes; Tritium; Vasoconstriction

2006
Comparative effects of 3,4-methylenedioxymethamphetamine and 4-methylthioamphetamine on rat liver mitochondrial function.
    Toxicology, 2010, Apr-11, Volume: 270, Issue:2-3

    Topics: Adrenergic Uptake Inhibitors; Amphetamines; Animals; Energy Metabolism; Hallucinogens; Hepatocytes; Hydrogen Peroxide; In Vitro Techniques; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Membranes; N-Methyl-3,4-methylenedioxyamphetamine; Oxygen Consumption; Rats; Rats, Wistar; Sulfhydryl Compounds

2010
Legal highs: the dark side of medicinal chemistry.
    Nature, 2011, Jan-06, Volume: 469, Issue:7328

    Topics: Amphetamines; Animals; Depression; Designer Drugs; Drug Design; Electronic Mail; Hallucinogens; Humans; Lysergic Acid Diethylamide; Mescaline; N-Methyl-3,4-methylenedioxyamphetamine; Parkinson Disease; Research Personnel; Schizophrenia; Substance-Related Disorders

2011
The risky cocktail: what combination effects can we expect between ecstasy and other amphetamines?
    Archives of toxicology, 2013, Volume: 87, Issue:1

    Topics: Amphetamines; Cell Line; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Humans; Illicit Drugs; Methamphetamine; Models, Theoretical; N-Methyl-3,4-methylenedioxyamphetamine; Regression Analysis

2013
Combination effects of amphetamines under hyperthermia - the role played by oxidative stress.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:6

    Topics: Adenosine Triphosphate; Amphetamines; Cell Survival; Dextroamphetamine; Dose-Response Relationship, Drug; Energy Metabolism; Glutathione; Hep G2 Cells; Hepatocytes; Humans; Hyperthermia, Induced; Lipid Peroxidation; Methamphetamine; Mitochondria, Liver; Mitochondrial Membranes; N-Methyl-3,4-methylenedioxyamphetamine; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Risk Assessment

2014
5-hydroxytryptamine- and dopamine-releasing effects of ring-substituted amphetamines on rat brain: a comparative study using in vivo microdialysis.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:8

    Topics: Amphetamines; Animals; Brain; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dopamine; Extracellular Fluid; Hydroxyindoleacetic Acid; Inhibitory Concentration 50; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin; Time Factors

2014