4-methylhistamine has been researched along with jnj 7777120 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Buschauer, A; Dove, S; Geyer, R; Igel, P; Seifert, R; Strasser, A | 1 |
| Buschauer, A; Geyer, R; Nordemann, U; Strasser, A; Wittmann, HJ | 1 |
| Chazot, P; Dijkstra, D; Gutzmer, R; Leurs, R; Shenton, FC; Stark, H; Werfel, T | 1 |
| Gschwandtner, M; Gutzmer, R; Schäkel, K; Werfel, T | 1 |
| Dartt, DA; Hayashi, C; Hayashi, D; Hodges, RR; Li, D; Shatos, M | 1 |
| Abd-Allah, AR; Abdel-Hamied, HE; Ahmad, SF; Alrashidi, I; Ashour, AE; Attia, SM; Bakheet, SA; Zoheir, KM | 2 |
| Cai, WK; He, GH; Hu, J; Li, T; Ma, X; Meng, JR; Xu, GL; Yin, SJ; Zhao, CH | 1 |
| Ahmad, SF; Ansari, MA; Ashour, AE; Attia, SM; Bakheet, SA; Korashy, HM; Nadeem, A; Zoheir, KM | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Hoshani, AR; Al-Shabanah, OA; Ansari, MA; Attia, SM; Bakheet, SA; Nadeem, A; Zoheir, KM | 1 |
| Chlopicki, S; Grosicki, M; Kieć-Kononowicz, K; Wójcik, T | 1 |
| Ebenezer, AJ; Prasad, K; Rajan, S; Thangam, EB | 1 |
13 other study(ies) available for 4-methylhistamine and jnj 7777120
| Article | Year |
|---|---|
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists.
Topics: Animals; Drug Discovery; Guanidine; Guanidines; Guanosine Triphosphate; Histamine Agonists; Humans; Hydrolysis; Isotope Labeling; Mice; Models, Molecular; Protein Conformation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship; Substrate Specificity | 2009 |
Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.
Topics: Animals; Guanidines; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Histamine Agonists; Humans; Imidazoles; Mice; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Protein Conformation; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sf9 Cells; Spodoptera; Stereoisomerism; Structure-Activity Relationship | 2016 |
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor.
Topics: Calcium; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Down-Regulation; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Interferon-gamma; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 8; Methylhistamines; Monocytes; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation | 2007 |
Histamine H(4) receptor activation on human slan-dendritic cells down-regulates their pro-inflammatory capacity.
Topics: Amino Sugars; Cytokines; Dendritic Cells; Dermatitis, Atopic; Flow Cytometry; Histamine; Humans; Indoles; Inflammation; Interferon-gamma; Lipopolysaccharides; Methylhistamines; Piperazines; Psoriasis; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.
Topics: Animals; Blotting, Western; Cells, Cultured; Cimetidine; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Goblet Cells; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Male; Methylhistamines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles | 2012 |
Involvement of histamine 4 receptor in the pathogenesis and progression of rheumatoid arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Cytokines; Disease Progression; Female; Gene Expression Regulation; Humans; Immunophenotyping; Indoles; Injections, Intraperitoneal; Lymphocyte Activation; Matrix Metalloproteinase 3; Methylhistamines; Mice; Mice, Inbred BALB C; NF-kappa B; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Th1 Cells | 2014 |
Activation of histamine H4 receptors decreases epithelial-to-mesenchymal transition progress by inhibiting transforming growth factor-β1 signalling pathway in non-small cell lung cancer.
Topics: Animals; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclic AMP; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Immunohistochemistry; Indoles; Lung Neoplasms; Methylhistamines; Mice; Mice, Nude; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Snail Family Transcription Factors; Survival Analysis; Transcription Factors; Transforming Growth Factor beta1; Vimentin; Xenograft Model Antitumor Assays; Zinc Finger E-box-Binding Homeobox 1 | 2014 |
Role of a histamine 4 receptor as an anti-inflammatory target in carrageenan-induced pleurisy in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cytokines; Female; Indoles; Inflammation; Methylhistamines; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Piperazines; Pleurisy; Receptors, Histamine; Structure-Activity Relationship | 2014 |
Regulation of TNF-α and NF-κB activation through the JAK/STAT signaling pathway downstream of histamine 4 receptor in a rat model of LPS-induced joint inflammation.
Topics: Animals; Anti-Inflammatory Agents; Enzyme Activation; Female; Gene Expression Regulation; Histamine Agonists; Histamine Antagonists; I-kappa B Proteins; Indoles; Inflammation; Interleukin-1beta; Janus Kinase 1; Knee Joint; Lipopolysaccharides; Methylhistamines; NF-kappa B; NF-KappaB Inhibitor alpha; Piperazines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; RNA, Messenger; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2015 |
Histamine 4 receptor promotes expression of costimulatory B7.1/B7.2 molecules, CD28 signaling and cytokine production in stress-induced immune responses.
Topics: Analysis of Variance; Animals; B7-1 Antigen; CD28 Antigens; Corticosterone; Cytokines; Indoles; Male; Methylhistamines; Mice; Mice, Inbred BALB C; Piperazines; Receptors, Histamine; Restraint, Physical; RNA, Messenger; Signal Transduction; Spleen; Stress, Psychological; T-Lymphocytes | 2015 |
In vitro study of histamine and histamine receptor ligands influence on the adhesion of purified human eosinophils to endothelium.
Topics: Cell Adhesion; Cell Communication; Cell Line; Cell Separation; Cell Survival; Drug Inverse Agonism; Endothelium; Eosinophils; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Indoles; Ligands; Methylhistamines; N-Formylmethionine Leucyl-Phenylalanine; Piperazines; Piperidines; Receptors, Histamine | 2016 |
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells.
Topics: Calcium; Cell Line; Gene Expression Regulation; Gene Silencing; Histamine; Humans; Indoles; Interleukin-1beta; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mast Cells; Methylhistamines; Piperazines; Pyrilamine; Receptors, Histamine H4; RNA, Small Interfering | 2018 |