Page last updated: 2024-08-23

4-methylhistamine and histamine

4-methylhistamine has been researched along with histamine in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (50.62)	18.7374
1990's	17 (20.99)	18.2507
2000's	9 (11.11)	29.6817
2010's	13 (16.05)	24.3611
2020's	1 (1.23)	2.80

Authors

Authors	Studies
Timmerman, H	1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM	1
Arrang, JM; Chabret, C; Gbahou, F; Humbert-Claude, M; Tardivel-Lacombe, J; Vincent, L	1
Buschauer, A; Dove, S; Geyer, R; Igel, P; Seifert, R; Strasser, A	1
Buschauer, A; Dove, S; Igel, P	1
Boonnak, R; de Esch, IJ; de Graaf, C; de Kloe, G; Istyastono, EP; Jongejan, A; Leurs, R; Lim, H; Nijmeijer, S; Smit, J; Smits, RA; Wijtmans, M; Zuiderveld, O	1
Buschauer, A; Geyer, R; Nordemann, U; Strasser, A; Wittmann, HJ	1
Arakelian, MC; Libertun, C	1
Estañ, L; Martínez-Mir, MI; Morales-Olivas, FJ; Rubio, E	1
Estañ, LA; Martinez-Mir, I; Morales-Olivas, FJ; Rubio, E	1
Nowak, JZ; Sek, B	2
Akiyama, Y; Kamei, C; Mukai, T; Tasaka, K	1
Amerini, S; Cerbai, E; Mugelli, A	1
Bender, P; Hanna, N; Muirhead, K; Poste, G	1
Bugajski, J; Gadek-Michalska, A	1
Cortijo, J; Esplugues, J; Morcillo, EJ; Orón, JD; Ortiz, JL; Perpiñá, M; Sanz, C	1
Adaikan, PG; Lau, LC; Ratnam, SS	1
Rising, TJ; Steward, A	1
Knigge, U; Matzen, S; Warberg, J	1
Akahori, H; Kamei, C; Kitazumi, K; Tasaka, K	1
Beaudoin, J; Beaulieu, L; Hébert, J; Jobin, M	1
Kim, LE; Oudart, N; Sercombe, R; Teste, JF	1
Crook, RB; Farber, MB; Prusiner, SB	1
Kannisto, P; Owman, C; Schmidt, G; Sjöberg, NO	1
Aguilar, MJ; Morales-Olivas, FJ; Rubio, E	1
Bhattacharya, SK; Parmar, SS	1
Dhawan, BN; Dhawan, KN; Gulati, A; Shukla, R; Srimal, RC	1
Fujinuma, S; Kamikawa, Y; Shimo, Y	1
Adachi, K; Aoyagi, T; Halprin, KM; Levine, V; Woodyard, CW	1
Lindl, T	1
Donoso, AO; Zárate, MB	1
Bielkiewicz, B; Kordecka, A; Lebrecht, U; Maslinski, C; Nowak, JZ	1
Ikehara, I; Murakami, M; Saeki, K; Seo, S	1
Ikeda, S; Murakami, M; Nishibori, M; Saeki, K; Seo, S	1
Bugajski, J; Gadek, A	1
Murakami, M; Saeki, K; Seo, S	1
Nishibori, M	1
Donoso, AO; Seltzer, A; Zárate, MB	1
Brostoff, J; Chen, SH; Hall, TJ; Lydyard, PM	1
Cortijo, J; Esplugues, J; Morales-Olivas, FJ; Rubio, E	1
Davies, MG; Greaves, MW	1
Hirschowitz, BI; Molina, E; Rentz, J	1
Baker, AP; Chakrin, LW; Holden, DA; Smith, WJ; Sung, CP	1
Brink, C; Douglas, JS; Duncan, PG	1
Dabney, JM; Dobbins, DE; Premen, AJ; Soika, CY	1
Bradley, SL; Russell, JA	1
Brostoff, J; Hall, TJ; Lydyard, PM	1
Ray, A; Sen, P; Sharma, KK	1
Laher, I; McNeill, JH	1
Broadley, KJ; Wilson, C	1
Chiba, S; Ikeda, K; Iwatsuki, K	1
Dodds, WJ; Hogan, WJ; Honda, R; Toouli, J	1
Mio, M; Nakaya, N; Shimazawa, M; Tasaka, K	1
Kamei, C; Tasaka, K; Tsujimoto, S; Yoshida, T	1
Ballabeni, V; Barocelli, E; Bordi, F; Caretta, A; Impicciatore, M; Morini, G; Silva, C	1
Banchelli, G; Buffoni, F; Conforti, L; Ignesti, G; Pirisino, R; Raimondi, L	1
Nowak, JZ; Sek, B; Zawilska, JB	1
KAMEI, CH	1
Ali, AS; Ali, SA; Peter, J	2
Jørgensen, H; Kjaer, A; Knigge, U; Warberg, J; Willems, E	1
Feldman, L; Gueant, JL; Kanny, G; Mallie, JP; Moneret-Vautrin, DA; Schohn, H	1
Abe, T; Kamei, C; Mio, M; Shimada, K; Zhao, Q	1
BLASCHKO, H	1
Akagi, T; Iwagaki, H; Kubo, S; Mori, S; Morichika, T; Nishibori, M; Takahashi, HK; Tamura, R; Tanaka, N; Yoshino, T	1
Chazot, P; Dijkstra, D; Gutzmer, R; Leurs, R; Shenton, FC; Stark, H; Werfel, T	1
Center, DM; Cross, L; Cruikshank, WW; Green, DS; Kornfeld, H; McAllister, B; Morgan, RK	1
Belon, P; Boujenaini, N; Sainte-Laudy, J	1
Belon, P; Sainte-Laudy, J	1
Gschwandtner, M; Gutzmer, R; Schäkel, K; Werfel, T	1
Dartt, DA; Hayashi, C; Hayashi, D; Hodges, RR; Li, D; Shatos, M	1
Dandekar, RD; Khan, MM	1
Ciz, M; Jancinova, V; Lojek, A; Nosal, R; Vasicek, O	1
Feliszek, M; Schacht, D; Schlicker, E; Speckmann, V; Stark, H; von Lehe, M	1
Chlopicki, S; Grosicki, M; Kieć-Kononowicz, K; Wójcik, T	1
Arunachalam, P; Ebenezer, AJ; Elden, BT	1
Gutzmer, R; Kietzmann, M; Köther, B; Rossbach, K; Schaper, K; Stark, H; Werfel, T	1
Elden, BT; Kaliappan, I; Mariappanadar, V; Nagarajan, G; Tamizh, M	1
Ebenezer, AJ; Prasad, K; Rajan, S; Thangam, EB	1
Bäumer, W; Kietzmann, M; Mishra, SK; Rossbach, K; Stark, H; Wilzopolski, J	1

Reviews

1 review(s) available for 4-methylhistamine and histamine

Article	Year
Histamine H3 ligands: just pharmacological tools or potential therapeutic agents? Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: Animals; Histamine; Histamine Antagonists; Molecular Structure; Neurotransmitter Agents; Receptors, Histamine; Receptors, Histamine H3; Structure-Activity Relationship	1990

Trials

1 trial(s) available for 4-methylhistamine and histamine

Article	Year
Sensory responses of human skin to synthetic histamine analogues and histamine. British journal of clinical pharmacology, 1980, Volume: 9, Issue:5 Topics: Adult; Chlorpheniramine; Dimaprit; Female; Histamine; Humans; Male; Methylhistamines; Pruritus; Receptors, Histamine H1; Receptors, Histamine H2; Skin; Thiourea	1980

Other Studies

79 other study(ies) available for 4-methylhistamine and histamine

Article	Year
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4	2005
Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives. British journal of pharmacology, 2006, Volume: 147, Issue:7 Topics: Binding, Competitive; Colforsin; Cyclic AMP; DNA, Complementary; Histamine; Histamine H2 Antagonists; Humans; Imidazoles; In Vitro Techniques; Kidney; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Recombinant Proteins; Structure-Activity Relationship; Transfection	2006
Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Drug Discovery; Guanidine; Guanidines; Guanosine Triphosphate; Histamine Agonists; Humans; Hydrolysis; Isotope Labeling; Mice; Models, Molecular; Protein Conformation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship; Substrate Specificity	2009
Histamine H4 receptor agonists. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Animals; Benzimidazoles; Binding Sites; Clozapine; Guanidines; Humans; Ligands; Mice; Oximes; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship	2010
Triazole ligands reveal distinct molecular features that induce histamine H4 receptor affinity and subtly govern H4/H3 subtype selectivity. Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6 Topics: Alkynes; Azides; Click Chemistry; HEK293 Cells; Humans; Imidazoles; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Structure-Activity Relationship; Triazoles	2011
Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists. Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7 Topics: Animals; Guanidines; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Histamine Agonists; Humans; Imidazoles; Mice; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Protein Conformation; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sf9 Cells; Spodoptera; Stereoisomerism; Structure-Activity Relationship	2016
H1 and H2 histamine receptor participation in the brain control of prolactin secretion in lactating rats. Endocrinology, 1977, Volume: 100, Issue:3 Topics: Animals; Diphenhydramine; Female; Histamine; Injections, Intraventricular; Lactation; Methylhistamines; Metiamide; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Secretory Rate	1977
Effect of histamine and histamine analogues on human isolated myometrial strips. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Acetylcholine; Adult; Atropine; Benzimidazoles; Dose-Response Relationship, Drug; Female; Histamine; Histamine Agonists; Humans; Methylhistamines; Middle Aged; Muscle Relaxation; Muscle, Smooth; Myometrium; Potassium Chloride; Pyridines; Ranitidine; Uterine Contraction	1992
Influence of hormonal treatment on the response of the rat isolated uterus to histamine and histamine receptor agonists. European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1 Topics: Animals; Drug Interactions; Estrogens; Female; Histamine; Methylhistamines; Potassium Chloride; Progesterone; Pyridines; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Uterine Contraction; Uterus	1992
Cyclic AMP generating systems in vertebrate retina: effects of histamine and an established retinal modulator, dopamine. Agents and actions, 1991, Volume: 33, Issue:1-2 Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Chickens; Cimetidine; Colforsin; Cyclic AMP; Dimaprit; Dopamine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistamines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Retina; Thiazoles; Thiourea	1991
Histamine lipolysis I: changes in the free fatty acid levels of dog plasma after intravenous infusion of histamine. Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:5 Topics: Aminophylline; Animals; Chromatography, High Pressure Liquid; Diphenhydramine; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Infusions, Intravenous; Lipolysis; Male; Methylhistamines; Pentobarbital; Pyrilamine; Starvation	1990
Histamine and abnormal automaticity in barium- and strophanthidin-treated sheep Purkinje fibers. Agents and actions, 1990, Volume: 31, Issue:1-2 Topics: Animals; Barium; Dimaprit; Electrophysiology; Heart; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Membrane Potentials; Methylhistamines; Purkinje Fibers; Sheep; Strophanthidin; Thiourea	1990
Binding of histamine and histamine analogs to lymphocyte subsets analyzed by flow cytometry. Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 135, Issue:6 Topics: Binding Sites; Binding, Competitive; Cold Temperature; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Histamine; Humans; Kinetics; Lymphocytes; Methylhistamines; Serum Albumin, Bovine; Staining and Labeling	1985
Antagonistic action of naloxone on central histamine receptors-stimulated corticosterone secretion in rats under stress. Agents and actions, 1989, Volume: 28, Issue:3-4 Topics: Animals; Cimetidine; Corticosterone; Dimaprit; Histamine; Male; Methylhistamines; Naloxone; Pituitary-Adrenal System; Pyridines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Restraint, Physical; Stress, Physiological; Thiourea	1989
Responses to histamine and selective H2-receptor agonists in lung parenchymal strips from normal and sensitized guinea-pigs. Agents and actions, 1989, Volume: 28, Issue:1-2 Topics: Animals; Benzimidazoles; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Histamine; Imidazoles; Impromidine; Isoproterenol; Lung; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; Receptors, Histamine H2; Thiourea	1989
Effect of histamine on human vas deferens in vitro. British journal of urology, 1989, Volume: 64, Issue:4 Topics: Burimamide; Cimetidine; Culture Techniques; Dose-Response Relationship, Drug; Histamine; Humans; Male; Methylhistamines; Muscle Contraction; Pyrilamine; Vas Deferens	1989
The determination of receptor constants for histamine H2-agonists in the guinea-pig isolated right atrium using an irreversible H2-antagonist. British journal of pharmacology, 1986, Volume: 87, Issue:1 Topics: Animals; Dimaprit; Dose-Response Relationship, Drug; Female; Guanidines; Guinea Pigs; Heart Rate; Histamine; Histamine H2 Antagonists; Imidazoles; Impromidine; In Vitro Techniques; Male; Methylhistamines; Receptors, Adrenergic, beta; Receptors, Histamine; Receptors, Histamine H2; Thiazoles; Thiourea	1986
Histaminergic stimulation of prolactin secretion mediated via H1- or H2-receptors: dependence on routes of administration. Neuroendocrinology, 1986, Volume: 44, Issue:1 Topics: Animals; Cimetidine; Dimaprit; Histamine; Histamine H1 Antagonists; Male; Methylhistamines; Pituitary Gland, Anterior; Prolactin; Pyrilamine; Pyrimidinones; Rats; Receptors, Histamine; Thiazoles; Thiourea	1986
The effects of histamine and some related compounds on conditioned avoidance response in rats. Life sciences, 1985, Nov-25, Volume: 37, Issue:21 Topics: Acetylcholine; Animals; Avoidance Learning; Dimaprit; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Hypothalamus; Injections, Intraventricular; Kinetics; Male; Methylhistamines; Pyrilamine; Rats; Rats, Inbred Strains; Scopolamine; Thiazoles; Thiourea	1985
Effects of H1 and H2 receptor agonists on nonspecific proliferative response of human peripheral blood lymphocytes. International archives of allergy and applied immunology, 1986, Volume: 79, Issue:3 Topics: Cimetidine; Dimaprit; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Humans; Immunosuppressive Agents; Lymphocyte Activation; Methylhistamines; Phytohemagglutinins; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea	1986
Participation of vascular H1-receptors in histaminergic relaxation of rabbit middle cerebral artery in vitro. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 283, Issue:2 Topics: Animals; Cerebral Arteries; Cimetidine; Dimaprit; Drug Interactions; Histamine; In Vitro Techniques; Methylhistamines; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Thiourea	1986
H2 histamine receptors on the epithelial cells of choroid plexus. Journal of neurochemistry, 1986, Volume: 46, Issue:2 Topics: Animals; Cattle; Choroid Plexus; Cyclic AMP; Diphenhydramine; Dose-Response Relationship, Drug; Epithelium; Histamine; Methylhistamines; Metiamide; Receptors, Histamine; Receptors, Histamine H2	1986
Alteration by histamine of the sympathetic nerve-mediated contractions in the bovine ovarian follicle wall in vitro. European journal of pharmacology, 1987, Mar-03, Volume: 135, Issue:1 Topics: Animals; Cattle; Cimetidine; Electrolytes; Female; Glucose; Histamine; In Vitro Techniques; Methylhistamines; Muscle Contraction; Norepinephrine; Ovary; Proteins; Pyrilamine; Sympathetic Nervous System	1987
Pharmacological investigation into the effects of histamine and histamine analogues on guinea-pig and rat colon in vitro. British journal of pharmacology, 1986, Volume: 88, Issue:3 Topics: Animals; Colon; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Methylhistamines; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Histamine	1986
Antinociceptive effect of intracerebroventricularly administered histamine in rats. Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:1 Topics: 5,6-Dihydroxytryptamine; Analgesics; Animals; Dexamethasone; Endorphins; Female; Histamine; Injections, Intraventricular; Male; Methylhistamines; Rats; Rats, Inbred Strains; Serotonin	1985
Evidence for the involvement of histamine in the regulation of blood-brain barrier permeability. Pharmacological research communications, 1985, Volume: 17, Issue:4 Topics: Animals; Blood-Brain Barrier; Colforsin; Diterpenes; Dogs; Female; Fluorescein; Fluoresceins; Histamine; Histamine Antagonists; Male; Methylhistamines; Metiamide; Pyrilamine; Time Factors	1985
Pharmacological characterization of the histamine receptor in the isolated muscularis mucosae of the guinea-pig oesophagus. British journal of pharmacology, 1985, Volume: 86, Issue:3 Topics: Animals; Calcium; Carbachol; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; Phenoxybenzamine; Pyridines; Receptors, Histamine	1985
The effect of histamine on epidermal outgrowth: its possible dual role as an inhibitor and stimulator. The Journal of investigative dermatology, 1981, Volume: 76, Issue:1 Topics: Animals; Cells, Cultured; Cimetidine; Cyclic AMP; Cyclic GMP; Epidermis; Epinephrine; Histamine; Histamine H1 Antagonists; Methylhistamines; Swine	1981
Effects of histamine agonists and antagonists (H1 and H2) on ganglionic transmission and on accumulation of cyclic nucleotides (cAMP and cGMP) in rat superior cervical ganglion in vitro. Neuropharmacology, 1983, Volume: 22, Issue:2 Topics: Action Potentials; Animals; Cyclic AMP; Cyclic GMP; Ganglia, Sympathetic; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Methylhistamines; Pyridines; Rats; Rats, Inbred Strains; Synaptic Transmission	1983
Release of prolactin and luteinizing hormone by histamine agonists in ovariectomized, steroid-treated rats under ether anesthesia. Experimental brain research, 1983, Volume: 52, Issue:2 Topics: Animals; Castration; Dimaprit; Female; Histamine; Histamine H1 Antagonists; Luteinizing Hormone; Methylhistamines; Metiamide; Pituitary Gland, Anterior; Prolactin; Pyridines; Pyrilamine; Rats; Thiourea	1983
Effects of the histamine H2-receptor agonists dimaprit and 4-methylhistamine on the central noradrenaline and serotonin system. Agents and actions, 1980, Volume: 10, Issue:1 Pt 2 Topics: Animals; Behavior, Animal; Brain; Dimaprit; Female; Histamine; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Methylhistamines; Norepinephrine; Rats; Receptors, Histamine; Receptors, Histamine H2; Serotonin; Thiourea; Tranylcypromine	1980
Effect of histamine on cyclic AMP levels in the submandibular gland. Agents and actions, 1981, Volume: 11, Issue:1-2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Female; Guinea Pigs; Histamine; Methylhistamines; Metiamide; Pyrilamine; Submandibular Gland	1981
Amylase secretion induced by histamine from guinea-pig parotid gland. Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 255, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Atropine; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methylhistamines; Metiamide; Parotid Gland; Propranolol; Pyrilamine; Stimulation, Chemical; Time Factors	1982
Central H1- and H2-histaminergic stimulation of pituitary-adrenocortical response under stress in rats. Neuroendocrinology, 1983, Volume: 36, Issue:6 Topics: Animals; Corticosterone; Dimaprit; Histamine; Histamine Antagonists; Male; Methylhistamines; Pituitary-Adrenal System; Pyridines; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stress, Physiological; Thiourea	1983
Cyclic AMP increase by histamine and its analogues in guinea-pig submandibular gland. Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 249, Issue:1 Topics: Animals; Cyclic AMP; Female; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Methylhistamines; Pyridines; Receptors, Histamine H1; Receptors, Histamine H2; Submandibular Gland	1981
Cyclic AMP increase in canine parotid gland mediated by histamine H2-receptors. European journal of pharmacology, 1981, Dec-17, Volume: 76, Issue:4 Topics: Animals; Cyclic AMP; Dimaprit; Dogs; Female; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Parotid Gland; Pyridines; Receptors, Histamine; Receptors, Histamine H2; Thiourea	1981
Histamine-induced prolactin release: pharmacological characterization of receptors in male rats. Neuroendocrinology, 1983, Volume: 36, Issue:6 Topics: Anesthesia; Animals; Furans; Histamine; Male; Methylhistamines; Metiamide; Prolactin; Pyrilamine; Ranitidine; Rats; Receptors, Histamine	1983
Modulation of human natural killer cell activity by pharmacological mediators. Clinical and experimental immunology, 1983, Volume: 54, Issue:2 Topics: Bucladesine; Cell Movement; Cells, Cultured; Cytotoxicity, Immunologic; Dibutyryl Cyclic GMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Histamine; Humans; Indomethacin; Killer Cells, Natural; Methylhistamines; Prostaglandins E; Prostaglandins F	1983
The inhibitory effect of histamine on the motility of rat uterus in vivo. European journal of pharmacology, 1984, Jan-13, Volume: 97, Issue:1-2 Topics: Adrenalectomy; Animals; Catecholamines; Estrogens; Female; Histamine; Hydroxydopamines; Methylhistamines; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Receptors, Histamine H2; Reserpine; Uterine Contraction; Uterus	1984
Histamine H-2 receptor stimulation and inhibition of pepsin secretion in the dog. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:3 Topics: Animals; Dogs; Gastric Juice; Gastric Mucosa; Guanidines; Histamine; Imidazoles; Impromidine; Methylhistamines; Pepsin A; Receptors, Histamine; Receptors, Histamine H2	1981
Effect of histamine agonists and antagonists on the production of murine reaginic antibodies. International journal of immunopharmacology, 1981, Volume: 3, Issue:4 Topics: Animals; Antibody Formation; Dimaprit; Histamine; Histamine Antagonists; Immunoglobulin E; Male; Methylhistamines; Metiamide; Mice; Reagins; Receptors, Histamine; Thiourea	1981
Changes in the response of guinea-pig airways in vivo and in vitro to cimetidine and propranolol during development. British journal of pharmacology, 1982, Volume: 75, Issue:3 Topics: Aging; Airway Resistance; Animals; Bronchi; Cimetidine; Dimaprit; Female; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Methylhistamines; Muscle Contraction; Propranolol; Receptors, Histamine; Receptors, Histamine H2; Thiourea; Trachea	1982
Effects of histamine-receptor agonists on transvascular fluid and macromolecular efflux in the canine forelimb. Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:4 Topics: Animals; Blood Pressure; Body Fluids; Dogs; Edema; Female; Forelimb; Heart Rate; Histamine; Lymph; Male; Methylhistamines; Proteins; Pyridines; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2	1984
Distribution of histamine receptors in isolated canine airways. Journal of applied physiology: respiratory, environmental and exercise physiology, 1983, Volume: 54, Issue:3 Topics: Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Methylhistamines; Metiamide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Respiratory System; Tissue Distribution	1983
Effect of histamine, H1 and H2 agonists on E-rosette formation in normal and atopic subjects. International archives of allergy and applied immunology, 1982, Volume: 69, Issue:4 Topics: Animals; Binding, Competitive; Dose-Response Relationship, Immunologic; Histamine; Humans; Hypersensitivity, Immediate; Lymphocytes; Methylhistamines; Neuraminidase; Pyridines; Receptors, Histamine H1; Receptors, Histamine H2; Rosette Formation; Sheep	1982
Effect of histaminergic drugs on footshock-induced aggressive behaviour in rats. European journal of pharmacology, 1981, Jul-17, Volume: 73, Issue:2-3 Topics: Aggression; Animals; Catecholamines; Electroshock; Histamine; Humans; Male; Methylhistamines; Pyridines; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2	1981
Effects of histamine in the isolated kitten heart. Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:11 Topics: Animals; Cats; Female; Heart; Heart Rate; Histamine; In Vitro Techniques; Male; Methylhistamines; Myocardial Contraction	1980
Further characterization of the guinea pig left atrial tension response to histamine by use of selective agonists. Agents and actions, 1981, Volume: 11, Issue:3 Topics: Animals; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; In Vitro Techniques; Male; Methylhistamines; Myocardial Contraction; Pyridines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2	1981
Effect of histamine on pancreatic exocrine secretion in the dog. Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 251, Issue:1 Topics: Animals; Cholecystokinin; Dogs; Female; Histamine; Male; Methylhistamines; Pancreas; Pancreatic Juice; Receptors, Histamine; Regional Blood Flow; Secretin	1981
Effect of histamine on motor function of opossum sphincter of Oddi. The American journal of physiology, 1981, Volume: 241, Issue:2 Topics: Ampulla of Vater; Animals; Female; Histamine; Male; Methylhistamines; Metiamide; Motor Activity; Opossums; Pyridines; Pyrilamine; Receptors, Histamine H1; Sphincter of Oddi; Sympatholytics; Tetrodotoxin	1981
Stimulatory effect of histamine on cyclic AMP formation in chick pineal gland. Journal of neurochemistry, 1994, Volume: 63, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; Adenine; Analysis of Variance; Animals; Carbon Radioisotopes; Chickens; Colforsin; Cyclic AMP; Dimaprit; Guinea Pigs; Hippocampus; Histamine; Histamine Agonists; In Vitro Techniques; Kinetics; Male; Methylhistamines; Pineal Gland; Ranitidine; Rats; Rats, Wistar; Thiazoles; Tritium	1994
Histamine-induced production of interleukin-1 alpha from murine bone marrow stromal cells and its inhibition by H2 blockers. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Animals; Blotting, Western; Bone Marrow; Bone Marrow Cells; Carbazoles; Cells, Cultured; Colony-Forming Units Assay; Cyclic AMP; Granulocytes; Histamine; Histamine H2 Antagonists; Indoles; Interleukin-1; Male; Methylhistamines; Mice; Mice, Inbred BALB C; Protein Kinase C; Protein Precursors; Pyrroles; Stromal Cells; T-Lymphocytes	1993
Changes in plasma adrenocorticotropic hormone and cortisol levels induced by intracerebroventricular injection of histamine and its related compounds in dogs. Pharmacology, 1993, Volume: 47, Issue:2 Topics: Adrenocorticotropic Hormone; Animals; Cimetidine; Dogs; Hexamethonium; Hexamethonium Compounds; Histamine; Hydrocortisone; Hypophysectomy; Injections, Intraventricular; Male; Methylhistamines; Pyrilamine	1993
Pharmacological profile of new thioperamide derivatives at histamine peripheral H1-, H2-, H3-receptors in guinea-pig. Agents and actions, 1993, Volume: 38, Issue:3-4 Topics: Animals; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Ileum; In Vitro Techniques; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; Piperidines; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3	1993
Histamine lipolytic activity and semicarbazide-sensitive amine oxidase (SSAO) of rat white adipose tissue (WAT). Biochemical pharmacology, 1993, Oct-19, Volume: 46, Issue:8 Topics: Adipose Tissue; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Cimetidine; Histamine; Isoproterenol; Kinetics; Lipolysis; Male; Methylhistamines; Pyrilamine; Rats; Rats, Wistar; Semicarbazides	1993
A bizarre receptor mediating stimulatory effect of histamine on cyclic AMP formation in duck pineal gland. Neuroscience letters, 1995, Dec-29, Volume: 202, Issue:1-2 Topics: Animals; Cyclic AMP; Ducks; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Methylhistamines; Pineal Gland; Pyrilamine; Ranitidine; Receptors, Histamine	1995
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR. Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:4 Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Ileum; Iris; Lethal Dose 50; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Piperidines; Potassium; Pyrilamine; Ranitidine; Receptors, Histamine H1; Substance P	1996
Effect of histaminergic drugs on integumental melanophores of adult Bufo melanostictus. Indian journal of experimental biology, 1996, Volume: 34, Issue:5 Topics: Animals; Bufonidae; Cell Aggregation; Histamine; Histamine Agents; In Vitro Techniques; Melanophores; Methylhistamines; Metiamide; Pyrilamine	1996
Histamine receptors in the skin melanophores of Indian bullfrog Rana tigerina. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 1998, Volume: 121, Issue:3 Topics: Animals; Edetic Acid; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Melanins; Melanophores; Methylhistamines; Metiamide; p-Methoxy-N-methylphenethylamine; Pyrilamine; Ranidae; Receptors, Histamine; Skin; Skin Pigmentation	1998
Histaminergic and catecholaminergic interactions in the central regulation of vasopressin and oxytocin secretion. Endocrinology, 1999, Volume: 140, Issue:8 Topics: Animals; Arginine Vasopressin; Blood Pressure; Cerebral Ventricles; Cimetidine; Epinephrine; Histamine; Histamine Agonists; Hypothalamus; Imidazoles; Infusions, Parenteral; Male; Methylhistamines; Norepinephrine; Oxytocin; Pituitary Gland, Posterior; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H2; Thiazoles; Thiourea	1999
Abnormalities in histamine pharmacodynamics in chronic urticaria. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Amine Oxidase (Copper-Containing); Chronic Disease; Diuresis; Female; Food Hypersensitivity; Histamine; Histamine N-Methyltransferase; Humans; Intestinal Mucosa; Male; Methylation; Methylhistamines; Middle Aged; Time Factors; Urticaria	1993
Effects of histamine and related compounds on the differentiation of HL-60-Eo cells into eosinophils. Methods and findings in experimental and clinical pharmacology, 2001, Volume: 23, Issue:7 Topics: Cell Differentiation; Cell Division; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Eosinophils; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; HL-60 Cells; Humans; Impromidine; Methylhistamines; Ranitidine; Receptors, Histamine H2; Thymidine; Time Factors; Tritium	2001
Oxidation of 1, 4-methylhistamine by mammalian plasma. The Journal of physiology, 1959, Volume: 148 Topics: Animals; Histamine; Methylhistamines; Oxidation-Reduction	1959
Histamine downregulates CD14 expression via H2 receptors on human monocytes. Clinical immunology (Orlando, Fla.), 2003, Volume: 108, Issue:3 Topics: Cells, Cultured; Dimaprit; Down-Regulation; Histamine; Histamine Agonists; Histamine H2 Antagonists; Humans; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; Methylhistamines; Monocytes; Receptors, Histamine H2; Time Factors; Tumor Necrosis Factor-alpha	2003
Histamine downregulates monocyte CCL2 production through the histamine H4 receptor. The Journal of allergy and clinical immunology, 2007, Volume: 120, Issue:2 Topics: Calcium; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Down-Regulation; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Interferon-gamma; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Matrix Metalloproteinase 8; Methylhistamines; Monocytes; Piperazines; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiourea; Up-Regulation	2007
Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model. Journal of immunology (Baltimore, Md. : 1950), 2007, Jun-15, Volume: 178, Issue:12 Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; CD4 Antigens; Cell Movement; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Histamine; Humans; Interleukin-16; Interleukin-2 Receptor alpha Subunit; Lung; Lymphocyte Activation; Methylhistamines; Mice; Mice, Inbred BALB C; Mice, Knockout; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Respiratory Hypersensitivity; T-Lymphocytes, Regulatory	2007
Confirmation of biological effects of high dilutions. Effects of submolecular concentrations of histamine and 1-, 3- and 4-methylhistamines on human basophil activation. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2008, Volume: 57 Suppl 1 Topics: Basophils; Histamine; Humans; Indicator Dilution Techniques; Methylhistamines	2008
Inhibition of basophil activation by histamine: a sensitive and reproducible model for the study of the biological activity of high dilutions. Homeopathy : the journal of the Faculty of Homeopathy, 2009, Volume: 98, Issue:4 Topics: Alcian Blue; Animals; Antigens, CD; Basophils; Cimetidine; Coloring Agents; Enzyme Inhibitors; Flow Cytometry; Histamine; Histamine Agonists; Histamine H2 Antagonists; Histidine; Humans; Methylhistamines; Mice; Platelet Membrane Glycoproteins; Staining and Labeling; Tetraspanin 30	2009
Histamine H(4) receptor activation on human slan-dendritic cells down-regulates their pro-inflammatory capacity. Immunology, 2011, Volume: 132, Issue:1 Topics: Amino Sugars; Cytokines; Dendritic Cells; Dermatitis, Atopic; Flow Cytometry; Histamine; Humans; Indoles; Inflammation; Interferon-gamma; Lipopolysaccharides; Methylhistamines; Piperazines; Psoriasis; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2011
Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion. Investigative ophthalmology & visual science, 2012, May-17, Volume: 53, Issue:6 Topics: Animals; Blotting, Western; Cells, Cultured; Cimetidine; Conjunctiva; Conjunctivitis, Allergic; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Goblet Cells; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Indoles; Male; Methylhistamines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles	2012
Involvement of histamine receptors in SAPK/JNK phosphorylation. International immunopharmacology, 2012, Volume: 13, Issue:2 Topics: Animals; Betahistine; Female; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; MAP Kinase Signaling System; Methylhistamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Spleen; Tetradecanoylphorbol Acetate; Thiazoles; Tumor Necrosis Factor-alpha	2012
Role of histamine receptors in the effects of histamine on the production of reactive oxygen species by whole blood phagocytes. Life sciences, 2014, Mar-28, Volume: 100, Issue:1 Topics: Benzimidazoles; Dimaprit; Guanidines; Histamine; Histamine Agonists; Humans; Male; Methylhistamines; Phagocytes; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H2; Receptors, Histamine H4; Thiourea	2014
A search for functional histamine H4 receptors in the human, guinea pig and mouse brain. Naunyn-Schmiedeberg's archives of pharmacology, 2015, Volume: 388, Issue:1 Topics: Adolescent; Adult; Animals; Cerebral Cortex; Child; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Histamine; Histamine Agonists; Humans; Male; Methylhistamines; Mice, Inbred C57BL; Middle Aged; Norepinephrine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Young Adult	2015
In vitro study of histamine and histamine receptor ligands influence on the adhesion of purified human eosinophils to endothelium. European journal of pharmacology, 2016, Apr-15, Volume: 777 Topics: Cell Adhesion; Cell Communication; Cell Line; Cell Separation; Cell Survival; Drug Inverse Agonism; Endothelium; Eosinophils; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Indoles; Ligands; Methylhistamines; N-Formylmethionine Leucyl-Phenylalanine; Piperazines; Piperidines; Receptors, Histamine	2016
H4R activation utilizes distinct signaling pathways for the production of RANTES and IL-13 in human mast cells. Journal of receptor and signal transduction research, 2017, Volume: 37, Issue:2 Topics: Chemokine CCL5; Chromones; Flavonoids; Gene Expression Regulation; Histamine; Histamine Antagonists; Humans; Interleukin-13; MAP Kinase Signaling System; Mast Cells; Methylhistamines; Morpholines; NF-kappa B; Oncogene Protein v-akt; Phosphorylation; Receptors, Histamine	2017
Stimulation of the histamine 4 receptor upregulates thymic stromal lymphopoietin (TSLP) in human and murine keratinocytes. Pharmacological research, 2016, Volume: 113, Issue:Pt A Topics: Animals; Cell Line; Cytokines; HEK293 Cells; Histamine; Humans; Keratinocytes; Methylhistamines; Mice; Poly I-C; Pyridines; Receptors, Histamine; RNA, Messenger; Sensory Receptor Cells; Thymic Stromal Lymphopoietin; Up-Regulation	2016
Effect of H4R antagonist N-(2-aminoethyl)-5-chloro-1H-indol-2-carboxamides and 5-chloro-2-(piperazin-1-ylmethyl)-1H-benzimidazole on histamine and 4-methylhistamine-induced mast cell response. Journal of receptor and signal transduction research, 2017, Volume: 37, Issue:3 Topics: Calcium; Histamine; Histamine Antagonists; Humans; Hypersensitivity; Inflammation; Mast Cells; Methylhistamines; NF-kappa B; Phosphorylation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Signal Transduction	2017
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells. Journal of receptor and signal transduction research, 2018, Volume: 38, Issue:3 Topics: Calcium; Cell Line; Gene Expression Regulation; Gene Silencing; Histamine; Humans; Indoles; Interleukin-1beta; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mast Cells; Methylhistamines; Piperazines; Pyrilamine; Receptors, Histamine H4; RNA, Small Interfering	2018
TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch. Biomolecules, 2021, 08-06, Volume: 11, Issue:8 Topics: Acetanilides; Animals; Calcium; Capsaicin; Female; Ganglia, Spinal; Gene Expression; Histamine; Male; Methylhistamines; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Molecular Imaging; Primary Cell Culture; Pruritus; Purines; Ruthenium Red; Sensory Receptor Cells; Signal Transduction; TRPA1 Cation Channel; TRPV Cation Channels	2021