4-methylglutamic acid has been researched along with kainic acid in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carver, JM; Cortes-Burgos, L; Giordano, T; Howe, JR; Mansson, PE; Shu, J; Zhou, LM | 1 |
| Costa, AM; Giordano, T; Gu, ZQ; Jones, KA; Mansson, PE; Skolnick, P; Yamada, KA; Zhou, LM | 1 |
| Huettner, JE; Wilding, TJ | 1 |
| Constantino, MD; Cunha, RA; Ribeiro, JA | 1 |
| Costa, AM; Huettner, JE; Jones, KA; Wilding, TJ | 1 |
| Dai, WM; Ebert, B; Lambert, JD; Madsen, U | 1 |
| Bleakman, D; Hoo, K; Ogden, AM; Ornstein, PL | 1 |
| Morsette, DJ; Sidorowicz, H; Sladek, CD | 1 |
| Ambrósio, AF; Carvalho, AP; Carvalho, CM; Malva, JO; Salgado, AJ; Silva, AP | 1 |
| Shen, W; Slaughter, MM | 1 |
| Apricò, K; Beart, PM; Crawford, D; O'Shea, RD | 1 |
| Hamanaka, N; Ito, S; Matsumura, S; Minami, T; Nishizawa, M; Sasaguri, Y | 1 |
| Mayer, ML | 1 |
| Galik, J; Gerber, G; Park, YK; Randić, M; Voitenko, N; Youn, DH | 1 |
| Bhatt, D; Chung, WY; Cooper, RL; Lee, JY | 1 |
| Joseph, DJ; MacDermott, AB; Williams, DJ | 1 |
16 other study(ies) available for 4-methylglutamic acid and kainic acid
| Article | Year |
|---|---|
Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors.
Topics: Cell Line; Cell Survival; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Kainic Acid; L-Lactate Dehydrogenase; Ligands; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins | 1996 |
(2S,4R)-4-methylglutamic acid (SYM 2081): a selective, high-affinity ligand for kainate receptors.
Topics: Animals; Dose-Response Relationship, Drug; Glutamates; Humans; Kainic Acid; Ligands; Male; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Structure-Activity Relationship | 1997 |
Activation and desensitization of hippocampal kainate receptors.
Topics: Animals; Animals, Newborn; Benzodiazepines; Cells, Cultured; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Lanthanum; Membrane Potentials; Neurons; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate | 1997 |
Inhibition of [3H] gamma-aminobutyric acid release by kainate receptor activation in rat hippocampal synaptosomes.
Topics: Animals; Excitatory Amino Acid Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Rats; Rats, Wistar; Receptors, Kainic Acid; Synaptic Transmission; Synaptosomes | 1997 |
Desensitization of kainate receptors by kainate, glutamate and diastereomers of 4-methylglutamate.
Topics: Animals; Cells, Cultured; Ganglia, Spinal; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Osmolar Concentration; Patch-Clamp Techniques; Rats; Receptors, Kainic Acid; Stereoisomerism | 1997 |
Studies of the antagonist actions of (RS)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl] propionic acid (ATPO) on non-NMDA receptors in cultured rat neurones.
Topics: Adrenal Cortex Hormones; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Isoxazoles; Kainic Acid; Neurons; Organophosphonates; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1998 |
Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; GluK2 Kainate Receptor; Glutamates; Hippocampus; Humans; Isoquinolines; Kainic Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quinoxalines; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Fusion Proteins; Tetrazoles | 1999 |
Role of non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophysial explants.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Glutamates; Hypothalamo-Hypophyseal System; Kainic Acid; Kinetics; Male; N-Methylaspartate; Organ Culture Techniques; Oxytocin; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Vasopressins | 2001 |
Role of kainate receptor activation and desensitization on the [Ca(2+)](i) changes in cultured rat hippocampal neurons.
Topics: Animals; Benzodiazepines; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Chelating Agents; Concanavalin A; Excitatory Amino Acid Antagonists; Fetus; Fura-2; GluK3 Kainate Receptor; Glutamates; Hippocampus; Immunohistochemistry; Kainic Acid; Microscopy, Confocal; Microtubule-Associated Proteins; Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Tetrazolium Salts; Thiazoles | 2001 |
A non-excitatory paradigm of glutamate toxicity.
Topics: Action Potentials; Ambystoma; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cell Death; Excitatory Amino Acid Agonists; Glutamates; Glutamic Acid; Kainic Acid; Neuroprotective Agents; Patch-Clamp Techniques; Receptors, Kainic Acid; Retinal Ganglion Cells | 2002 |
Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Binding, Competitive; Blotting, Western; Cell Membrane; Cells, Cultured; D-Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Glutamates; Kainic Acid; Ligands; Mice; Potassium; Serine; Sodium; Temperature; Tritium | 2004 |
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Basidiomycota; Benzodiazepines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Heterocyclic Compounds; Indoles; Injections, Spinal; Japan; Kainic Acid; Lumbosacral Region; Male; Mice; Mice, Inbred Strains; Mushroom Poisoning; Oximes; Pain; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spider Venoms; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Time Factors | 2004 |
Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallization; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GluK2 Kainate Receptor; Glutamates; Glutamic Acid; Kainic Acid; Ligands; Macromolecular Substances; Models, Biological; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Quisqualic Acid; Receptors, Kainic Acid | 2005 |
Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cadmium Chloride; Calcium; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Subunits; Receptors, Kainic Acid; Substantia Gelatinosa | 2005 |
Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Cycloleucine; Dose-Response Relationship, Drug; Drosophila; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamates; Kainic Acid; Larva; Neuromuscular Junction; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2009 |
Modulation of neurite outgrowth by activation of calcium-permeable kainate receptors expressed by rat nociceptive-like dorsal root ganglion neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Deaminase; Analysis of Variance; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Ganglia, Spinal; GAP-43 Protein; Gene Expression Regulation; GluK2 Kainate Receptor; Glutamates; Growth Cones; Kainic Acid; Membrane Proteins; Neurites; Neuromuscular Depolarizing Agents; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; RNA Editing; RNA, Messenger; Sensory Receptor Cells; Spider Venoms; Subcellular Fractions | 2011 |