4-methyl-4-aza-3-oxopregnane-20-carboxylate has been researched along with 17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one in 3 studies
| Studies (4-methyl-4-aza-3-oxopregnane-20-carboxylate) | Trials (4-methyl-4-aza-3-oxopregnane-20-carboxylate) | Recent Studies (post-2010) (4-methyl-4-aza-3-oxopregnane-20-carboxylate) | Studies (17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one) | Trials (17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one) | Recent Studies (post-2010) (17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 81 | 0 | 4 |
| Protein | Taxonomy | 4-methyl-4-aza-3-oxopregnane-20-carboxylate (IC50) | 17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one (IC50) |
|---|---|---|---|
| Androgen receptor | Rattus norvegicus (Norway rat) | 2.8 | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Homo sapiens (human) | 0.0029 | |
| Androgen receptor | Mus musculus (house mouse) | 0.463 | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Rattus norvegicus (Norway rat) | 0.0106 | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Homo sapiens (human) | 0.0023 | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Rattus norvegicus (Norway rat) | 0.0106 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kadohama, N; Karr, JP; Kim, U; Murphy, GP; Sandberg, AA; Wakisaka, M | 1 |
| Brooks, JR; Liang, T; Rasmusson, GH | 1 |
| Ahmed, S; Denison, S | 1 |
3 other study(ies) available for 4-methyl-4-aza-3-oxopregnane-20-carboxylate and 17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one
| Article | Year |
|---|---|
Retardation of prostate tumor progression in the Noble rat by 4-methyl-4-aza-steroidal inhibitors of 5 alpha-reductase.
Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Castration; Dihydrotestosterone; Male; Organ Size; Oxidoreductases; Pregnanes; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Steroids, Heterocyclic | 1985 |
12. Androgens: Pharmacodynamics and antagonists. Biochemical and biological studies with 4-aza-steroidal 5 alpha-reductase inhibitors.
Topics: 5-alpha Reductase Inhibitors; Animals; Azasteroids; Binding, Competitive; Dihydrotestosterone; Kinetics; Male; Oxidoreductases; Pregnanes; Prostate; Rats; Receptors, Androgen; Steroids, Heterocyclic; Structure-Activity Relationship | 1983 |
Mechanism based representation of the active site of 5 alpha-reductase (5AR).
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Azasteroids; Binding Sites; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Models, Chemical; Models, Molecular; NADP; Pregnanes; Structure-Activity Relationship; Testosterone | 1998 |