4-methoxynitracrine has been researched along with amsacrine in 1 studies
*Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent. [MeSH]
*Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent. [MeSH]
| Studies (4-methoxynitracrine) | Trials (4-methoxynitracrine) | Recent Studies (post-2010) (4-methoxynitracrine) | Studies (amsacrine) | Trials (amsacrine) | Recent Studies (post-2010) (amsacrine) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 1,293 | 127 | 120 |
| Protein | Taxonomy | 4-methoxynitracrine (IC50) | amsacrine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Homo sapiens (human) | 5 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 7.43 | |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | 5.47 | |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | 5 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 1.88 | |
| Aldehyde oxidase | Homo sapiens (human) | 3.2 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.2095 | |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | 6.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, RF; Denny, WA; Thompson, LH; Wilson, WR | 1 |
1 other study(ies) available for 4-methoxynitracrine and amsacrine
| Article | Year |
|---|---|
Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.
Topics: Aminoacridines; Animals; Cell Division; Cell Line; DNA; Nitracrine; Oxygen; Structure-Activity Relationship | 1989 |