4-methoxyindole-3-acetonitrile and dinoprostone

4-methoxyindole-3-acetonitrile has been researched along with dinoprostone in 2 studies

Compound Research Comparison

Studies (4-methoxyindole-3-acetonitrile)	Trials (4-methoxyindole-3-acetonitrile)	Recent Studies (post-2010) (4-methoxyindole-3-acetonitrile)	Studies (dinoprostone)	Trials (dinoprostone)	Recent Studies (post-2010) (dinoprostone)
6	0	4	29,105	1,346	6,357

Protein Interaction Comparison

Protein	Taxonomy	dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtype	Homo sapiens (human)	0.0155
Prostaglandin E2 receptor EP4 subtype	Homo sapiens (human)	0.0031
Prostaglandin E2 receptor EP4 subtype	Rattus norvegicus (Norway rat)	0.0021
Prostaglandin E2 receptor EP3 subtype	Homo sapiens (human)	0.002
Prostaglandin E2 receptor EP2 subtype	Homo sapiens (human)	0.0087
Prostacyclin receptor	Homo sapiens (human)	0.26
Prostaglandin E2 receptor EP2 subtype	Rattus norvegicus (Norway rat)	0.0052

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baek, NI; Cho, YW; Choi, MS; Chung, HG; Jeong, TS; Kang, E; Lee, KT; Lee, YS; Noh, YS; Shin, JS	1
Kwon, BJ; Kwon, TH; Lee, KT; Lee, YH; Lee, YS; Shin, JS; Yoon, IH	1

Other Studies

2 other study(ies) available for 4-methoxyindole-3-acetonitrile and dinoprostone

Article	Year
Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinase. British journal of pharmacology, 2011, Volume: 164, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Brassica rapa; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation; I-kappa B Kinase; Indoles; Inflammation; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Shock, Septic; Tumor Necrosis Factor-alpha	2011
Synthesis of indolyl-3-acetonitrile derivatives and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells. Bioorganic & medicinal chemistry letters, 2013, May-01, Volume: 23, Issue:9 Topics: Acetonitriles; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Dinoprostone; Indoles; Lipopolysaccharides; Mice; Nitric Oxide	2013

Article

Year

Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinase.

British journal of pharmacology, 2011, Volume: 164, Issue:1

Topics: Animals; Anti-Inflammatory Agents; Brassica rapa; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation; I-kappa B Kinase; Indoles; Inflammation; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Shock, Septic; Tumor Necrosis Factor-alpha

2011

Synthesis of indolyl-3-acetonitrile derivatives and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells.

Bioorganic & medicinal chemistry letters, 2013, May-01, Volume: 23, Issue:9

Topics: Acetonitriles; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Dinoprostone; Indoles; Lipopolysaccharides; Mice; Nitric Oxide

2013