Page last updated: 2024-09-04

4-methoxy-2-naphthylamine and chloroquine

4-methoxy-2-naphthylamine has been researched along with chloroquine in 1 studies

*Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. [MeSH]

*Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. [MeSH]

Compound Research Comparison

Studies
(4-methoxy-2-naphthylamine)
Trials
(4-methoxy-2-naphthylamine)
Recent Studies (post-2010)
(4-methoxy-2-naphthylamine)
Studies
(chloroquine)
Trials
(chloroquine)
Recent Studies (post-2010) (chloroquine)
100116,4057634,029

Protein Interaction Comparison

ProteinTaxonomy4-methoxy-2-naphthylamine (IC50)chloroquine (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei43
Spike glycoproteinBetacoronavirus England 15.47
Replicase polyprotein 1abBetacoronavirus England 15.47
Transmembrane protease serine 2Homo sapiens (human)5.47
Dihydrofolate reductase Bos taurus (cattle)0.0301
Amyloid-beta precursor proteinHomo sapiens (human)7
Histidine-rich protein PFHRP-IIPlasmodium falciparum (malaria parasite P. falciparum)0.2383
Procathepsin LHomo sapiens (human)5.47
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus5.47
Replicase polyprotein 1abHuman coronavirus 229E5.47
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus5.47
Spike glycoproteinSevere acute respiratory syndrome coronavirus 23.58
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.375
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.5
Serine/threonine-protein kinase mTORHomo sapiens (human)0.27
Beta-secretase 1Homo sapiens (human)7
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus5.47
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.503
Angiotensin-converting enzyme 2 Homo sapiens (human)6.235
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.02
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.2

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aerts, JM; Luiken, JJ; Meijer, AJ1

Other Studies

1 other study(ies) available for 4-methoxy-2-naphthylamine and chloroquine

ArticleYear
The role of the intralysosomal pH in the control of autophagic proteolytic flux in rat hepatocytes.
    European journal of biochemistry, 1996, Feb-01, Volume: 235, Issue:3

    Topics: 2-Naphthylamine; Animals; Autophagy; Biological Transport; Chloroquine; Hydrogen-Ion Concentration; Hydrolysis; Liver; Lysosomes; Male; Osmolar Concentration; Rats; Rats, Wistar

1996