Compounds > 4-ipomeanol
Page last updated: 2024-08-23

4-ipomeanol and phenobarbital

4-ipomeanol has been researched along with phenobarbital in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyd, MR1
Boyd, MR; Burka, LT; Sastry, BV; Wilson, BJ1
Boyd, MR; Statham, CN1
Boyd, MR; Franklin, RB; Sasame, HA1
Boyd, MR; Buckpitt, AR1

Other Studies

5 other study(ies) available for 4-ipomeanol and phenobarbital

ArticleYear
Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues.
    Ciba Foundation symposium, 1980, Volume: 76

    Topics: Animals; Biotransformation; Bromobenzenes; Chloramphenicol; Furans; Humans; Liver; Lung; Methylcholanthrene; Microsomes; Models, Biological; Monocrotaline; Pharmaceutical Preparations; Phenobarbital; Pyrrolizidine Alkaloids; Terpenes

1980
Development of tolerance to the pulmonary toxin, 4-ipomeanol.
    Toxicology, 1981, Volume: 19, Issue:2

    Topics: Animals; Carbon Tetrachloride; Drug Resistance; Drug Tolerance; Enzyme Induction; Furans; Lung; Male; Mice; Naphthalenes; Phenobarbital; Proadifen; Rabbits; Rats; Terpenes; Thiourea; Time Factors; Toxins, Biological

1981
Effects of phenobarbital and 3-methylcholanthrene on the in vivo distribution, metabolism and covalent binding of 4-ipomeanol in the rat; implications for target organ toxicity.
    Biochemical pharmacology, 1982, Dec-15, Volume: 31, Issue:24

    Topics: Animals; Biotransformation; Liver; Male; Methylcholanthrene; Organ Specificity; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Terpenes; Time Factors; Tissue Distribution

1982
Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
    Biochemical and biophysical research communications, 1980, Apr-29, Volume: 93, Issue:4

    Topics: Alkylating Agents; Animals; Biotransformation; Furans; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Rats; Terpenes

1980
The in vitro formation of glutathione conjugates with the microsomally activated pulmonary bronchiolar aklylating agent and cytotoxin, 4-ipomeanol.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:1

    Topics: Alkylating Agents; Animals; Furans; Glutathione; Glutathione Transferase; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Rats; Terpenes

1980