4-ipomeanol has been researched along with nadp in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyd, MR; Burka, LT; Sasame, HA; Wilson, BJ | 1 |
| Boyd, MR; Philpot, RM; Slaughter, SR; Statham, CN | 1 |
| Boyd, MR; Franklin, RB; Sasame, HA | 1 |
| Alvarez-Diez, TM; Zheng, J | 1 |
| Baer, BR; Henne, KR; Rettie, AE | 1 |
| Burka, LT; Chen, LJ; DeRose, EF | 1 |
6 other study(ies) available for 4-ipomeanol and nadp
| Article | Year |
|---|---|
In vitro studies on the metabolic activation of the pulmonary toxin, 4-ipomeanol, by rat lung and liver microsomes.
Topics: Alkylation; Animals; Biotransformation; Enzyme Induction; Epoxide Hydrolases; Furans; Glutathione; In Vitro Techniques; Kinetics; Lung; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Rats; Subcellular Fractions; Terpenes; Toxins, Biological | 1978 |
Covalent binding of metabolites of 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins and to the enzymes of the pulmonary cytochrome P-450-dependent monooxygenase system.
Topics: Animals; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Fluoroscopy; In Vitro Techniques; Lung; Microsomes; Microsomes, Liver; NADP; Oxygenases; Protein Binding; Rabbits; Terpenes; Toxins, Biological | 1983 |
Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
Topics: Alkylating Agents; Animals; Biotransformation; Furans; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Rats; Terpenes | 1980 |
Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
Topics: Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microsomes, Liver; NADP; Substrate Specificity; Terpenes | 2004 |
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
Topics: Acetylcysteine; Aldehydes; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Glutathione; Humans; Liver; Lung; Lysine; NADP; Pyrroles; Rabbits; Spectrometry, Mass, Electrospray Ionization; Terpenes | 2005 |
Metabolism of furans in vitro: ipomeanine and 4-ipomeanol.
Topics: Acetylation; Animals; Cysteine; Furans; Glutathione; Glycine; Methylation; Microsomes; Molecular Structure; NADP; Oxidation-Reduction; Rats; Rats, Inbred F344; Terpenes | 2006 |