Page last updated: 2024-09-04

4-iodophenylalanine and phenylalanine

4-iodophenylalanine has been researched along with phenylalanine in 23 studies

Compound Research Comparison

Studies
(4-iodophenylalanine)
Trials
(4-iodophenylalanine)
Recent Studies (post-2010)
(4-iodophenylalanine)
Studies
(phenylalanine)
Trials
(phenylalanine)
Recent Studies (post-2010) (phenylalanine)
272523,6957214,367

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's1 (4.35)18.2507
2000's14 (60.87)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujibayashi, Y; Kawai, K; Konishi, J; Saji, H; Yokoyama, A1
Hancock, WS; Harding, DR; Sparrow, JT1
Chevrier, B; D'Orchymont, H; Moras, D; Schalk, C; Tarnus, C1
Feiden, W; Heimann, A; Kempski, O; Kirsch, CM; Richter, S; Romeike, BF; Samnick, S1
Bader, JB; Feiden, W; Hellwig, D; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S1
Anderson, JC; Chin, JW; Cropp, TA; Mukherji, M; Schultz, PG; Zhang, Z1
Amon, M; Feiden, W; Hellwig, D; Kirsch, CM; Kubuschok, B; Menger, MD; Romeike, BF; Samnick, S1
Brock, A; Schultz, PG; Spraggon, G; Wang, L; Wu, N; Xie, J1
Blumberg, S; Gilboa, R; Reiland, V; Schomburg, D; Shoham, G; Shoham, Y; Spungin-Bialik, A1
Dauter, Z1
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Sell, N1
Bauwens, M; Cornelissen, B; De Spiegeleer, B; Dierckx, RA; Kersemans, K; Kersemans, V; Mertens, J; Slegers, G1
Fukuzawa, S; Kigawa, T; Kodama, K; Matsuda, N; Nakayama, H; Sakamoto, K; Shirouzu, M; Tachibana, K; Takio, K; Yabuki, T; Yokoyama, S1
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S1
Brandau, W; Farmakis, G; Israel, I; Samnick, S1
Gouverneur, E; Hellwig, D; Kirsch, CM; Menges, M; Raedle, J; Samnick, S; Schaefer, A1
Melançon, CE; Schultz, PG1
Fukuzawa, S; Kigawa, T; Kitabatake, M; Kodama, K; Nakayama, H; Sakamoto, K; Takio, K; Yabuki, T; Yokoyama, S1
Chin, B; Grasfeder, L; McDougald, D; Vaidyanathan, G; Zalutsky, MR1
Karthikraj, R; Prabhakar, S; Vairamani, M1
Dießl, S; Flentje, M; Hänscheid, H; Israel, I; Löhr, M; Reiners, C; Samnick, S; Sweeney, R; Verburg, FA; Vince, GH1
Becker, ML; Li, S; Policastro, GM; Wade, MB; Yu, J1
Braun, TS; Drescher, M; Kugele, A; Schmidt, MJ; Summerer, D; Widder, P; Williams, L1

Trials

2 trial(s) available for 4-iodophenylalanine and phenylalanine

ArticleYear
Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT.
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:9

    Topics: Adult; Aged; Brain Neoplasms; Female; Humans; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon

2005
Intra-individual comparison of p-[123I]-iodo-L-phenylalanine and L-3-[123I]-iodo-alpha-methyl-tyrosine for SPECT imaging of gliomas.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:1

    Topics: Adult; Aged; Brain; Brain Neoplasms; Cell Count; Female; Glioma; Humans; Male; Methyltyrosines; Middle Aged; Phenylalanine; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon

2008

Other Studies

21 other study(ies) available for 4-iodophenylalanine and phenylalanine

ArticleYear
[Metabolic studies of p-iodophenylalanine in the pancreas: a gateway to the development of radioiodinated amino acids for functional diagnosis].
    Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:11

    Topics: Animals; Biological Transport, Active; Iodine Radioisotopes; Male; Mice; Pancreas; Phenylalanine; Rats

1988
Synthesis of peptide labelled with p-iodophenylalanine which corresponds to the first amphipathic region of apolipoprotein C-I.
    International journal of peptide and protein research, 1985, Volume: 26, Issue:2

    Topics: Amino Acid Sequence; Apolipoprotein C-I; Apolipoproteins C; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Peptides; Phenylalanine; Protein Binding

1985
The structure of the Aeromonas proteolytica aminopeptidase complexed with a hydroxamate inhibitor. Involvement in catalysis of Glu151 and two zinc ions of the co-catalytic unit.
    European journal of biochemistry, 1996, Apr-15, Volume: 237, Issue:2

    Topics: Aeromonas; Amino Acid Sequence; Aminopeptidases; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Glutamic Acid; Hydroxamic Acids; Models, Molecular; Molecular Structure; Phenylalanine; Protein Conformation; Zinc

1996
Investigation of iodine-123-labelled amino acid derivatives for imaging cerebral gliomas: uptake in human glioma cells and evaluation in stereotactically implanted C6 glioma rats.
    European journal of nuclear medicine, 2000, Volume: 27, Issue:10

    Topics: Alanine; Amino Acids; Amino Acids, Cyclic; Animals; beta-Alanine; Binding, Competitive; Blood-Brain Barrier; Brain Neoplasms; Cysteine; Glioblastoma; Humans; Iodine Radioisotopes; Isoquinolines; Male; Methyltyrosines; Neoplasm Transplantation; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serine; Tetrahydroisoquinolines; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured

2000
Initial evaluation of the feasibility of single photon emission tomography with p-[123 I]iodo-L-phenylalanine for routine brain tumour imaging.
    Nuclear medicine communications, 2002, Volume: 23, Issue:2

    Topics: Adult; Aged; Animals; Astrocytoma; Brain Neoplasms; Feasibility Studies; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Retrospective Studies; Tomography, Emission-Computed, Single-Photon; Whole-Body Counting

2002
An expanded eukaryotic genetic code.
    Science (New York, N.Y.), 2003, Aug-15, Volume: 301, Issue:5635

    Topics: Amino Acids; Anticodon; Azides; Codon, Nonsense; Escherichia coli; Genetic Code; Humans; Methyltyrosines; Mutation; Phenylalanine; Protein Biosynthesis; RNA, Transfer; Saccharomyces cerevisiae; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine-tRNA Ligase

2003
p-[123I]iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.
    European journal of nuclear medicine and molecular imaging, 2004, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Drug Evaluation, Preclinical; Humans; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Pancreatic Neoplasms; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution

2004
The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination.
    Nature biotechnology, 2004, Volume: 22, Issue:10

    Topics: Amino Acid Substitution; Bacteriophage T4; Crystallography, X-Ray; Molecular Probe Techniques; Molecular Probes; Muramidase; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Proteins

2004
Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase.
    Acta crystallographica. Section D, Biological crystallography, 2004, Volume: 60, Issue:Pt 10

    Topics: Amino Acids; Aminopeptidases; Binding Sites; Crystallization; Crystallography, X-Ray; Electrons; Hydrogen Bonding; Models, Molecular; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Streptomyces griseus; Tryptophan; Zinc

2004
Phasing in iodine for structure determination.
    Nature biotechnology, 2004, Volume: 22, Issue:10

    Topics: Amino Acid Substitution; Bacteriophage T4; Crystallography, X-Ray; Molecular Probe Techniques; Molecular Probes; Muramidase; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Proteins

2004
123/125I-labelled 2-iodo-L: -phenylalanine and 2-iodo-D: -phenylalanine: comparative uptake in various tumour types and biodistribution in mice.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:8

    Topics: Animals; Carcinoma; Cell Line, Tumor; Female; Humans; Isotope Labeling; Metabolic Clearance Rate; Mice; Organ Specificity; Phenylalanine; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2006
A new protein engineering approach combining chemistry and biology, part I; site-specific incorporation of 4-iodo-L-phenylalanine in vitro by using misacylated suppressor tRNAPhe.
    Chembiochem : a European journal of chemical biology, 2006, Volume: 7, Issue:10

    Topics: Acylation; Cell-Free System; Escherichia coli; Phenylalanine; Protein Engineering; ras Proteins; RNA, Transfer; RNA, Transfer, Phe

2006
Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2008, Volume: 66, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Mice, Nude; Nuclear Medicine; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Specific Pathogen-Free Organisms; Tissue Distribution; Xenograft Model Antitumor Assays

2008
Para-[(123)I]iodo-L-phenylalanine in patients with pancreatic adenocarcinoma: tumour uptake, whole-body kinetics, dosimetry.
    Nuklearmedizin. Nuclear medicine, 2008, Volume: 47, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Female; Half-Life; Humans; Iodine Radioisotopes; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Whole-Body Irradiation

2008
One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetases.
    Bioorganic & medicinal chemistry letters, 2009, Jul-15, Volume: 19, Issue:14

    Topics: Amino Acyl-tRNA Synthetases; Chloramphenicol O-Acetyltransferase; Codon, Terminator; Directed Molecular Evolution; Escherichia coli; Methanococcus; Pentosyltransferases; Phenylalanine; Plasmids; Tyrosine-tRNA Ligase

2009
Site-specific incorporation of 4-iodo-L-phenylalanine through opal suppression.
    Journal of biochemistry, 2010, Volume: 148, Issue:2

    Topics: Base Sequence; Cell-Free System; Codon, Terminator; Escherichia coli; Indoles; Phenylalanine; ras Proteins; RNA, Transfer

2010
An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:10

    Topics: Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Female; Humans; Iodine Radioisotopes; Isotope Labeling; Phenylalanine; Radiopharmaceuticals

2011
Differentiation of enantiomeric drugs by iodo-substituted L-amino acid references under electrospray ionization mass spectrometric conditions.
    Rapid communications in mass spectrometry : RCM, 2012, Jun-15, Volume: 26, Issue:11

    Topics: Diiodotyrosine; Pharmaceutical Preparations; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2012
Patients with recurrent glioblastoma multiforme. Initial experience with p-[(131)I]iodo-L-phenylalanine and external beam radiation therapy.
    Nuklearmedizin. Nuclear medicine, 2013, Volume: 52, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Phenylalanine; Pilot Projects; Radionuclide Imaging; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Conformal; Treatment Outcome

2013
Radiopaque, iodine functionalized, phenylalanine-based poly(ester urea)s.
    Biomacromolecules, 2015, Feb-09, Volume: 16, Issue:2

    Topics: Animals; Cell Survival; Contrast Media; Mice; NIH 3T3 Cells; Phenylalanine; Polyesters; Urea

2015
Site-directed spin labelling of proteins by Suzuki-Miyaura coupling via a genetically encoded aryliodide amino acid.
    Chemical communications (Cambridge, England), 2019, Feb-07, Volume: 55, Issue:13

    Topics: Amino Acids; Electron Spin Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phenylalanine; Proteins; Spin Labels

2019