4-iodine-benzo(b)thiophene-2-carboxamidine has been researched along with benzamidine in 2 studies
*benzamidine: RN given refers to parent cpd [MeSH]
*benzamidine: RN given refers to parent cpd [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, H; Katz, BA; Luong, C; Mackman, R; Martelli, A; Radika, K; Sprengeler, PA; Wang, J; Wong, L | 1 |
| Chan, H; Gjerstad, E; Ho, JD; Janc, JW; Katz, BA; Luong, C; Mackman, RL; McGrath, ME; Mortara, K; Somoza, JR; Sprengeler, PA; Tang, J; Verner, E; Williams, SR; Young, WB | 1 |
2 other study(ies) available for 4-iodine-benzo(b)thiophene-2-carboxamidine and benzamidine
| Article | Year |
|---|---|
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.
Topics: Amidines; Binding Sites; Drug Design; Factor Xa; Glycosylation; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Recombinant Proteins; Serine Proteinase Inhibitors; Substrate Specificity; Thiophenes; Thrombin; Tissue Plasminogen Activator; Trypsin; Urokinase-Type Plasminogen Activator | 2000 |
Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA).
Topics: Alanine; Amidines; Benzimidazoles; Binding Sites; Crystallography, X-Ray; Drug Design; Guanidine; Humans; Hydrogen Bonding; Indoles; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Protease Inhibitors; Protein Binding; Serine; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Urokinase-Type Plasminogen Activator; Water | 2004 |