4-hydroxyquinazoline has been researched along with febrifugine* in 1 studies
1 other study(ies) available for 4-hydroxyquinazoline and febrifugine
Article | Year |
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Enhancement of NO production in activated macrophages in vivo by an antimalarial crude drug, Dichroa febrifuga.
The effect of an antimalarial crude drug, Dichroafebrifuga Lour. on nitric oxide (NO) production in bacillus Calmette Guérin-induced mouse peritoneal macrophages activated by lipopolysaccharide was investigated. The NO production was significantly enhanced by an oral administration of a MeOH extract of D. febrifuga. Febrifugine (1) was isolated as the main active compound, and the activation was dose-dependent in the dosage range of 0.1-1 mg/kg/day. Topics: Animals; Antimalarials; China; In Vitro Techniques; Macrophages; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Nitric Oxide; Piperidines; Plant Extracts; Plant Roots; Plants, Medicinal; Quinazolines; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1998 |