4-hydroxypraziquantel has been researched along with praziquantel in 10 studies
*Praziquantel: An anthelmintic used in most schistosome and many cestode infestations. [MeSH]
*Praziquantel: An anthelmintic used in most schistosome and many cestode infestations. [MeSH]
| Studies (4-hydroxypraziquantel) | Trials (4-hydroxypraziquantel) | Recent Studies (post-2010) (4-hydroxypraziquantel) | Studies (praziquantel) | Trials (praziquantel) | Recent Studies (post-2010) (praziquantel) |
|---|---|---|---|---|---|
| 10 | 0 | 2 | 4,625 | 423 | 1,685 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chao-Ming, X; Cioli, D; Pica-Mattoccia, L; Ramana, AV; Ronketti, F; Todd, MH | 1 |
| Blaschke, G; Mehlhorn, H; Schmahl, G; Staudt, U | 1 |
| Guo, HF; Xiao, SH; You, JQ | 1 |
| Catto, BA; Guo, HF; Xiao, SH; You, JQ | 1 |
| Blaschke, G; Högemann, A; Kiec-Kononowicz, K; Westhoff, F | 1 |
| Liu, J; Stewart, JT | 1 |
| Blaschke, G; Lerch, C | 1 |
| Bonato, PS; Coelho, EB; Ferreira, MA; Garcia, HH; Lanchote, VL; Lima, RM; Marques, MP; Ponte, TM; Takayanagui, OM | 1 |
| Armstrong, DW; He, L; Lee, JT; Li, X; Wang, Y; Xie, J; Zhang, Y | 1 |
| He, L; Liu, R; Liu, S; Qiu, J; Shu, X; Wang, Y; Zhang, F; Zhang, M; Zheng, X; Zhou, T | 1 |
10 other study(ies) available for 4-hydroxypraziquantel and praziquantel
| Article | Year |
|---|---|
Praziquantel derivatives I: Modification of the aromatic ring.
Topics: Animals; Anthelmintics; Drug Evaluation, Preclinical; Magnetic Resonance Spectroscopy; Praziquantel; Schistosoma mansoni | 2007 |
Light and scanning electron microscopy studies on the effects of the enantiomers of praziquantel and its main metabolite on Schistosoma mansoni in vitro.
Topics: Animals; Female; Male; Microscopy, Electron, Scanning; Praziquantel; Schistosoma mansoni | 1992 |
Plasma pharmacokinetics and therapeutic efficacy of praziquantel and 4-hydroxypraziquantel in Schistosoma japonicum-infected rabbits after oral, rectal, and intramuscular administration.
Topics: Administration, Oral; Administration, Rectal; Animals; Injections, Intramuscular; Praziquantel; Rabbits; Schistosomiasis japonica | 1992 |
Uptake and effect of praziquantel and the major human oxidative metabolite, 4-hydroxypraziquantel, by Schistosoma japonicum.
Topics: Animals; Female; Male; Mice; Praziquantel; Schistosoma japonicum; Schistosomiasis japonica | 1991 |
Microsomal oxidation of praziquantel.
Topics: Animals; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; Molecular Conformation; Oxidation-Reduction; Praziquantel; Rats; Rats, Inbred Strains | 1990 |
High-performance liquid chromatography determination of praziquantel enantiomers in human serum using a reversed-phase cellulose-based chiral stationary phase and disc solid-phase extraction.
Topics: Antiplatyhelmintic Agents; Chromatography, High Pressure Liquid; Humans; Praziquantel; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 1997 |
Investigation of the stereoselective metabolism of praziquantel after incubation with rat liver microsomes by capillary electrophoresis and liquid chromatography-mass spectrometry.
Topics: Animals; Antiplatyhelmintic Agents; beta-Cyclodextrins; Chromatography, Liquid; Cyclodextrins; Electrophoresis, Capillary; Mass Spectrometry; Micelles; Microsomes, Liver; Praziquantel; Rats; Stereoisomerism; Surface-Active Agents | 1998 |
Enantioselective analysis of praziquantel and trans-4-hydroxypraziquantel in human plasma by chiral LC-MS/MS: Application to pharmacokinetics.
Topics: Chromatography, Liquid; Humans; Linear Models; Praziquantel; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tandem Mass Spectrometry | 2009 |
Selective Depletion of Chiral 4-Hydroxypraziquantel Metabolites in Three Types of Aquaculture Fish by LC-MS/MS.
Topics: Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Eels; Meat; Muscle, Skeletal; Perches; Praziquantel; Stereoisomerism; Tandem Mass Spectrometry; Tilapia | 2019 |
Stereoselective Pharmacokinetics and Residue Depletion of Praziquantel and Its Metabolites, 4-Hydroxypraziquantel Enantiomers, in Swine.
Topics: Animals; Liver; Praziquantel; Stereoisomerism; Swine | 2023 |