4-hydroxypenbutolol has been researched along with cimetidine in 1 studies
*Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output. [MeSH]
*Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output. [MeSH]
| Studies (4-hydroxypenbutolol) | Trials (4-hydroxypenbutolol) | Recent Studies (post-2010) (4-hydroxypenbutolol) | Studies (cimetidine) | Trials (cimetidine) | Recent Studies (post-2010) (cimetidine) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 9,473 | 1,687 | 377 |
| Protein | Taxonomy | 4-hydroxypenbutolol (IC50) | cimetidine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | 0.59 | |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | 8 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 0.82 | |
| Histamine H2 receptor | Homo sapiens (human) | 1.1742 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 1.02 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 0.82 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 3.0333 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajdu, P; Kirch, W; Mutschler, E; Ohnhaus, EE; Spahn, H | 1 |
1 other study(ies) available for 4-hydroxypenbutolol and cimetidine
| Article | Year |
|---|---|
Penbutolol Pharmacokinetics: the influence of concomitant administration of cimetidine.
Topics: Adult; Cimetidine; Drug Interactions; Glucuronates; Heart Rate; Humans; Kinetics; Penbutolol; Physical Exertion; Propanolamines; Time Factors | 1986 |