4-hydroxymephenytoin has been researched along with rifampin in 2 studies
| Studies (4-hydroxymephenytoin) | Trials (4-hydroxymephenytoin) | Recent Studies (post-2010) (4-hydroxymephenytoin) | Studies (rifampin) | Trials (rifampin) | Recent Studies (post-2010) (rifampin) |
|---|---|---|---|---|---|
| 36 | 5 | 0 | 20,468 | 1,499 | 6,552 |
| Protein | Taxonomy | 4-hydroxymephenytoin (IC50) | rifampin (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 2.949 | |
| Caspase-1 | Homo sapiens (human) | 8.319 | |
| Alpha-synuclein | Homo sapiens (human) | 7.1 | |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | 0.03 | |
| DNA-directed RNA polymerase subunit beta | Mycobacterium tuberculosis H37Rv | 0.01 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.5 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anthony, LB; Wilkinson, GR; Wood, AJ; Zhou, HH | 1 |
| Feng, HJ; Huang, SL; Wang, W; Zhou, HH | 1 |
2 other study(ies) available for 4-hydroxymephenytoin and rifampin
| Article | Year |
|---|---|
Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin.
Topics: Adult; Female; Humans; Hydroxylation; Male; Mephenytoin; Middle Aged; Phenotype; Rifampin | 1990 |
The induction effect of rifampicin on activity of mephenytoin 4'-hydroxylase related to M1 mutation of CYP2C19 and gene dose.
Topics: Adult; Antibiotics, Antitubercular; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Hydroxylation; Male; Mephenytoin; Mixed Function Oxygenases; Mutation; Rifampin; Stereoisomerism | 1998 |