4-hydroxymephenytoin has been researched along with nilutamide in 1 studies
| Studies (4-hydroxymephenytoin) | Trials (4-hydroxymephenytoin) | Recent Studies (post-2010) (4-hydroxymephenytoin) | Studies (nilutamide) | Trials (nilutamide) | Recent Studies (post-2010) (nilutamide) |
|---|---|---|---|---|---|
| 36 | 5 | 0 | 268 | 45 | 43 |
| Protein | Taxonomy | 4-hydroxymephenytoin (IC50) | nilutamide (IC50) |
|---|---|---|---|
| Androgen receptor | Homo sapiens (human) | 1.4045 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horsmans, Y; Lannes, D; Larrey, D; Letteron, P; Loeper, J; Pessayre, D; Tinel, M | 1 |
1 other study(ies) available for 4-hydroxymephenytoin and nilutamide
| Article | Year |
|---|---|
Nilutamide inhibits mephenytoin 4-hydroxylation in untreated male rats and in human liver microsomes.
Topics: Androgen Antagonists; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Female; Ferricyanides; Humans; Hydroxylation; Imidazoles; Imidazolidines; Male; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Troleandomycin | 1991 |