4-hydroxymephenytoin has been researched along with cycloguanil in 1 studies
| Studies (4-hydroxymephenytoin) | Trials (4-hydroxymephenytoin) | Recent Studies (post-2010) (4-hydroxymephenytoin) | Studies (cycloguanil) | Trials (cycloguanil) | Recent Studies (post-2010) (cycloguanil) |
|---|---|---|---|---|---|
| 36 | 5 | 0 | 231 | 16 | 37 |
| Protein | Taxonomy | 4-hydroxymephenytoin (IC50) | cycloguanil (IC50) |
|---|---|---|---|
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 5.8 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 2.985 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.45 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.11 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bochner, F; Coller, JK; Somogyi, AA | 1 |
1 other study(ies) available for 4-hydroxymephenytoin and cycloguanil
| Article | Year |
|---|---|
Comparison of (S)-mephenytoin and proguanil oxidation in vitro: contribution of several CYP isoforms.
Topics: Adult; Aged; Antibodies, Monoclonal; Anticonvulsants; Antimetabolites; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Folic Acid Antagonists; Genotype; Humans; In Vitro Techniques; Isoenzymes; Male; Mephenytoin; Microsomes, Liver; Middle Aged; Oxidation-Reduction; Proguanil; Triazines | 1999 |