4-hydroxylomustine has been researched along with lomustine in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farmer, PB; Foster, AB; Jarman, M; Oddy, MR; Reed, DJ | 1 |
| Clayton, SD; Frye, JL; Johnston, TP; Krauth, CA; McCaleb, GS; Montgomery, JA | 1 |
| Johnston, TP; Laster, WR; Mayo, JG; McCaleb, GS; Montgomery, JA | 1 |
| Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C | 1 |
| Bodor, N; Brewster, ME; Loftsson, T; Raghavan, K | 1 |
| Bodor, N; Raghavan, KS; Shek, E | 1 |
| Bleehen, NM; Lee, FY; Roberts, JT; Workman, P | 1 |
| Erickson, LC; Kohn, KW; Sariban, E | 1 |
8 other study(ies) available for 4-hydroxylomustine and lomustine
| Article | Year |
|---|---|
Synthesis, metabolism, and antitumor activity of deuterated analogues of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Deuterium; In Vitro Techniques; Isotope Labeling; Lomustine; Lymphoma; Mass Spectrometry; Microsomes, Liver; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Stereoisomerism | 1978 |
Synthesis of analogues of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Isomerism; Leukemia L1210; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Semustine; Structure-Activity Relationship | 1977 |
Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma.
Topics: Animals; Carcinoma; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Structure-Activity Relationship; Time Factors | 1977 |
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship | 1980 |
Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systems.
Topics: Animals; Brain; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Stability; Lomustine; Male; Membranes; Molecular Structure; Nitrosourea Compounds; Rats; Rats, Sprague-Dawley; Solubility; Tissue Distribution | 1992 |
Improved delivery through biological membranes. XXX. Synthesis and biological aspects of a 1,4-dihydropyridine based chemical delivery system for brain-sustained delivery of hydroxy CCNU.
Topics: Animals; Brain; Delayed-Action Preparations; Dihydropyridines; Lomustine; Male; Oxidation-Reduction; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Solubility | 1987 |
Clinical pharmacokinetics of oral CCNU (lomustine).
Topics: Administration, Oral; Adult; Biopsy; Cecal Neoplasms; Cell Line; Chromatography, High Pressure Liquid; Glioma; Half-Life; Humans; Kinetics; Lomustine; Male; Melanoma; Middle Aged | 1985 |
Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
Topics: Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Humans; Lomustine; Lung; Nitrosourea Compounds; Pregnancy; Structure-Activity Relationship | 1984 |