4-hydroxydebrisoquin has been researched along with quinidine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bertilsson, L; Dahl, ML; Eichelbaum, M; Ingelman-Sundberg, M; Johansson, I; Meese, CO; Säwe, J; Yue, QY | 1 |
| Andersson, K; Bertilsson, L; Dahl, M; Dalén, P | 1 |
| Katoh, M; Nakajima, M; Sawada, T; Soeno, Y; Tateno, C; Yokoi, T; Yoshizato, K | 1 |
1 trial(s) available for 4-hydroxydebrisoquin and quinidine
| Article | Year |
|---|---|
Inhibition of debrisoquine hydroxylation with quinidine in subjects with three or more functional CYP2D6 genes.
Topics: Administration, Oral; Adult; Alleles; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Dosage; Genotype; Humans; Hydroxylation; Male; Quinidine | 2000 |
2 other study(ies) available for 4-hydroxydebrisoquin and quinidine
| Article | Year |
|---|---|
Quinidine inhibition of debrisoquine S(+)-4- and 7-hydroxylations in Chinese of different CYP2D6 genotypes.
Topics: Asian People; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Genotype; Haplotypes; Humans; Hydroxylation; Metabolic Clearance Rate; Mixed Function Oxygenases; Polymorphism, Restriction Fragment Length; Quinidine; Stereoisomerism; White People | 1993 |
In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver.
Topics: Adrenergic Agents; Animals; Chimera; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Drug Interactions; Humans; Infant; Liver; Male; Mice; Mice, SCID; Models, Animal; Paroxetine; Quinidine; Urokinase-Type Plasminogen Activator | 2007 |