4-hydroxydebrisoquin has been researched along with metoprolol in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horai, Y; Ishikawa, K; Ishizaki, T; Taga, J | 1 |
| Avenant, J; Moncrieff, J; Sommers, DK | 1 |
| Cerqueira, PM; Cesarino, EJ; Lanchote, VL; Mateus, FH; Mere, Y; Santos, SR | 1 |
| Cerqueira, PM; Coelho, EB; Geleilete, TJ; Goldman, GH; Lanchote, VL | 1 |
2 trial(s) available for 4-hydroxydebrisoquin and metoprolol
| Article | Year |
|---|---|
Enantioselectivity in the steady-state pharmacokinetics of metoprolol in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Area Under Curve; Debrisoquin; Female; Half-Life; Humans; Hypertension; Male; Metoprolol; Middle Aged; Phenotype; Stereoisomerism | 1999 |
Influence of chronic renal failure on stereoselective metoprolol metabolism in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Cytochrome P-450 CYP2D6; Debrisoquin; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Mutation; Stereoisomerism | 2005 |
2 other study(ies) available for 4-hydroxydebrisoquin and metoprolol
| Article | Year |
|---|---|
Correlations among the metabolic ratios of three test probes (metoprolol, debrisoquine and sparteine) for genetically determined oxidation polymorphism in a Japanese population.
Topics: Adolescent; Adult; Debrisoquin; Female; Humans; Isoquinolines; Japan; Male; Metoprolol; Middle Aged; Oxidation-Reduction; Polymorphism, Genetic; Sparteine | 1990 |
Metoprolol alpha-hydroxylation polymorphism in the San Bushmen of southern Africa.
Topics: Black People; Debrisoquin; Humans; Hydroxylation; Male; Metoprolol; Nigeria; Polymorphism, Genetic; South Africa; White People | 1989 |