Page last updated: 2024-08-26

4-hydroxycyclophosphamide and thiotepa

4-hydroxycyclophosphamide has been researched along with thiotepa in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, LW; Black, KC; Chen, TL; Colvin, OM; Grochow, LB; Kennedy, MJ; Kiraly, SB1
Anderson, LW; Chen, TL; Collins, JM; Colvin, OM; Grochow, LB; Kennedy, MJ; Strong, JM1
Armstrong, DK; Chen, TL; Davidson, NE; Goodman, SN; Grochow, L; Hahm, HA; Kennedy, MJ; Passos-Coelho, J1
Beijnen, JH; Huitema, AD; Kerbusch, T; Rodenhuis, S; Tibben, MM1
Beijnen, JH; Dalesio, O; de Jonge, ME; Huitema, AD; Mathôt, RA; Rodenhuis, S1
Beijnen, JH; de Jonge, ME; Huitema, AD; Rodenhuis, S; van Dam, SM1

Trials

2 trial(s) available for 4-hydroxycyclophosphamide and thiotepa

ArticleYear
Cyclophosphamide and 4-Hydroxycyclophosphamide/aldophosphamide kinetics in patients receiving high-dose cyclophosphamide chemotherapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Microsomes, Liver; Middle Aged; Phosphoramide Mustards; Thiotepa

1996
Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Carboplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Phosphoramide Mustards; Prodrugs; Thiotepa; Time Factors; Triethylenephosphoramide

2005

Other Studies

4 other study(ies) available for 4-hydroxycyclophosphamide and thiotepa

ArticleYear
Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Liver Neoplasms; Middle Aged; Nonlinear Dynamics; Phosphoramide Mustards; Thiotepa

1997
Novobiocin in combination with high-dose chemotherapy for the treatment of advanced breast cancer: a phase 2 study.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:3A

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Middle Aged; Novobiocin; Survival Analysis; Thiotepa; Treatment Failure; Tumor Cells, Cultured; Tumor Stem Cell Assay

2000
Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.
    Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Cyclophosphamide; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Humans; Kinetics; Microsomes; Neoplasms; Thiotepa; Time Factors

2000
Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.
    Bone marrow transplantation, 2002, Volume: 30, Issue:9

    Topics: Adolescent; Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Cyclophosphamide; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Thiotepa; Triethylenephosphoramide

2002