4-hydroxycyclophosphamide has been researched along with aldophosphamide in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, KK; Hong, PS | 1 |
| Manthey, CL; Sladek, NE | 1 |
| Boyd, VL; Brandt, JA; Egan, W; Ludeman, SM; Ozkan, G; Shao, KL; Zon, G | 1 |
| Borch, RF; Hoye, TR; Swanson, TA | 1 |
| Egan, W; Ludeman, SM; Phillips, LR; Sweet, EM; Zon, G | 1 |
| Domeyer, BE; Sladek, NE | 1 |
| Anderson, LW; Colvin, OM; Grochow, LB; Ludeman, SM; Strong, JM | 1 |
| Bielenstein, M; Johansson, M | 1 |
| Anderson, LW; Black, KC; Chen, TL; Colvin, OM; Grochow, LB; Kennedy, MJ; Kiraly, SB | 1 |
| Anderson, LW; Chen, TL; Collins, JM; Colvin, OM; Grochow, LB; Kennedy, MJ; Strong, JM | 1 |
| Chiocca, EA; Colvin, OM; Fangmeier, J; Hochberg, FH; Ichikawa, T; Ludeman, SM; Petros, WP | 1 |
| Voelcker, G | 1 |
1 trial(s) available for 4-hydroxycyclophosphamide and aldophosphamide
| Article | Year |
|---|---|
Cyclophosphamide and 4-Hydroxycyclophosphamide/aldophosphamide kinetics in patients receiving high-dose cyclophosphamide chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Area Under Curve; Breast Neoplasms; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Microsomes, Liver; Middle Aged; Phosphoramide Mustards; Thiotepa | 1996 |
11 other study(ies) available for 4-hydroxycyclophosphamide and aldophosphamide
| Article | Year |
|---|---|
Analysis of 4-hydroxycyclophosphamide by gas chromatography-mass spectrometry in plasma.
Topics: Animals; Cyclophosphamide; Gas Chromatography-Mass Spectrometry; Humans; Male; Phosphoramide Mustards; Rats; Rats, Inbred Strains | 1989 |
Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenases.
Topics: Aldehyde Dehydrogenase; Animals; Cyclophosphamide; Female; Isoenzymes; Kinetics; Liver; Mice; Mice, Inbred DBA; Oxidation-Reduction; Phosphoramide Mustards | 1988 |
NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between
Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry; Cyclophosphamide; Deuterium; Fourier Analysis; Kinetics; Magnetic Resonance Spectroscopy; Phosphoramide Mustards; Stereoisomerism | 1984 |
In situ preparation and fate of cis-4-hydroxycyclophosphamide and aldophosphamide: 1H and 31P NMR evidence for equilibration of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and its hydrate in aqueous solution.
Topics: Cyclophosphamide; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Phosphoramide Mustards; Stereoisomerism | 1984 |
O-Methylhydroxylamine as a new trapping reagent for quantitative studies of 4-hydroxycyclophosphamide and aldophosphamide.
Topics: Cyclophosphamide; Drug Stability; Hydroxylamines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Phosphoramide Mustards | 1982 |
Inhibition by cyanamide of 4-hydroxycyclophosphamide/aldophosphamide oxidation to carboxyphosphamide.
Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Cyanamide; Cyanides; Cyclophosphamide; Drug Resistance; Female; Male; Mice; Oxidation-Reduction; Phosphoramide Mustards; Rats | 1981 |
Quantitation of 4-hydroxycyclophosphamide/aldophosphamide in whole blood.
Topics: Blood Specimen Collection; Cyclophosphamide; Drug Stability; Humans; Hydroxylamines; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Phosphoramide Mustards; Prodrugs | 1995 |
Determination of 4-hydroxycyclophosphamide in plasma, as 2,4-dinitrophenylhydrazone derivative of aldophosphamide, by liquid chromatography.
Topics: Breast Neoplasms; Chromatography, Liquid; Cyclophosphamide; Female; Humans; Hydrazones; Indicators and Reagents; Phosphoramide Mustards; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature | 1994 |
Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Liver Neoplasms; Middle Aged; Nonlinear Dynamics; Phosphoramide Mustards; Thiotepa | 1997 |
Intraneoplastic polymer-based delivery of cyclophosphamide for intratumoral bioconversion by a replicating oncolytic viral vector.
Topics: Animals; Antineoplastic Agents, Alkylating; Biocompatible Materials; Biotransformation; Cyclophosphamide; Cytochrome P-450 CYP2B1; Decanoic Acids; Drug Carriers; Genetic Therapy; Genetic Vectors; Glioblastoma; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intralesional; Kinetics; Mice; Mice, Nude; Phosphoramide Mustards; Polyesters; Prodrugs; Rats; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |
Causes and possibilities to circumvent cyclophosphamide toxicity.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Proliferation; Cyclophosphamide; Female; Leukemia P388; Male; Mice; Phosphoramide Mustards; Toxicity Tests | 2020 |