4-hydroxycinnamoylmethane and benzylideneacetone

4-hydroxycinnamoylmethane has been researched along with benzylideneacetone* in 1 studies

Other Studies

1 other study(ies) available for 4-hydroxycinnamoylmethane and benzylideneacetone

ArticleYear
Quantum chemical- and 3-D-QSAR (CoMFA) studies of benzalacetones and 1,1,1-trifluoro-4-phenyl-3-buten-2-ones.
    Bioorganic & medicinal chemistry letters, 2002, Sep-02, Volume: 12, Issue:17

    The inhibitory effect (IC(50)) of the title compounds on UV-induced mutagenesis in Escherichia coli WP2uvrA was analyzed quantitatively by using various quantum chemical descriptors and also by the CoMFA method: both approaches provided results of similar quality. The activity was shown to be increased by electron-withdrawing substituents and also by hydrogen-bonding between 2-hydroxy group and the bio-component.

    Topics: Antimutagenic Agents; Butanones; Electrons; Escherichia coli; Hydrogen Bonding; Inhibitory Concentration 50; Mutagenesis; Quantitative Structure-Activity Relationship; Ultraviolet Rays

2002