Compounds > 4-hydroxy-25-desoxyneorollinicin

Page last updated: 2024-09-03

4-hydroxy-25-desoxyneorollinicin and rotenone

4-hydroxy-25-desoxyneorollinicin has been researched along with rotenone in 12 studies

Compound Research Comparison

Studies (4-hydroxy-25-desoxyneorollinicin)	Trials (4-hydroxy-25-desoxyneorollinicin)	Recent Studies (post-2010) (4-hydroxy-25-desoxyneorollinicin)	Studies (rotenone)	Trials (rotenone)	Recent Studies (post-2010) (rotenone)
62	0	7	4,407	6	1,648

Protein Interaction Comparison

Protein	Taxonomy	4-hydroxy-25-desoxyneorollinicin (IC50)	rotenone (IC50)
Bile salt export pump	Homo sapiens (human)		8
NADH-ubiquinone oxidoreductase chain 1	Bos taurus (cattle)		0.015
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	Bos taurus (cattle)		0.0051
Cytochrome P450 2C19	Homo sapiens (human)		3.6486
5-hydroxytryptamine receptor 6	Homo sapiens (human)		0.87
Acyl carrier protein, mitochondrial	Bos taurus (cattle)		0.0051

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (83.33)	18.2507
2000's	1 (8.33)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cortes, D; Degli Esposti, M; Estornell, E; Ghelli, A; Ratta, M	1
Calhoun, MW; Friedrich, T; Fukumori, Y; Gennis, RB; Jacobson, BW; Leif, H; Meinhardt, SW; Ohnishi, T; Rudnitzky, NI; Sled, VD	1
Darrouzet, E; Dupuis, A	1
Benelli, B; Esposti, MD; Ghelli, A	1
Bacchilega, E; Carelli, V; Cortelli, P; Degli Esposti, M; Ghelli, A; Leuzzi, V; Lugaresi, E; Mancini, R; Montagna, P; Ratta, M; Sangiorgi, S	1
Brandt, U; Lümmen, P; Okun, JG	1
Bucchi, L; Carducci, C; Carelli, V; De Negri, A; Degli Esposti, M; Ghelli, A; Lenaz, G; Leuzzi, V; Lugaresi, E; Montagna, P	1
Casida, JE; Di Bernardo, S; Schuler, F; Singer, TP; Yagi, T; Yankovskaya, V; Yano, T	1
Byron, S; Esposti, MD; Georgiou, HM; Myers, MA	1
Cortes, D; Estornell, E; González, MC; Tormo, JR	1
Bergamini, C; Bortolus, M; Fato, R; Lenaz, G; Leoni, S; Maniero, AL; Ohnishi, T	1
Bayona-Bafaluy, MP; Emperador, S; Hernández-Ainsa, C; López-Gallardo, E; Montoya, J; Ruiz-Pesini, E	1

Other Studies

12 other study(ies) available for 4-hydroxy-25-desoxyneorollinicin and rotenone

Article	Year
Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I). The Biochemical journal, 1994, Jul-01, Volume: 301 ( Pt 1) Topics: Animals; Cattle; Electron Transport Complex I; Furans; In Vitro Techniques; Mitochondria, Heart; Molecular Structure; NADH, NADPH Oxidoreductases; Plants, Medicinal; Pyridines; Rotenone; Submitochondrial Particles	1994
Biophysical and biochemical studies of bacterial NADH:quinone oxidoreductase (NDH-1). Biochemical Society transactions, 1994, Volume: 22, Issue:1 Topics: Electron Spin Resonance Spectroscopy; Escherichia coli; Furans; Lactones; Pyridines; Quinone Reductases; Rhodobacter sphaeroides; Rotenone	1994
Genetic evidence for the existence of two quinone related inhibitor binding sites in NADH-CoQ reductase. Biochimica et biophysica acta, 1997, Mar-28, Volume: 1319, Issue:1 Topics: Binding Sites; Electron Transport Complex I; Enzyme Inhibitors; Furans; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Pyridines; Rhodobacter capsulatus; Rotenone	1997
Measurement of the membrane potential generated by complex I in submitochondrial particles. Journal of biochemistry, 1997, Volume: 121, Issue:4 Topics: Animals; Calibration; Cattle; Electrophysiology; Energy Metabolism; Enzyme Inhibitors; Furans; Ionophores; Isoxazoles; Membrane Potentials; Mitochondria, Heart; NAD(P)H Dehydrogenase (Quinone); Nigericin; Rotenone; Sensitivity and Specificity; Submitochondrial Particles; Time Factors; Ubiquinone; Uncoupling Agents	1997
Leber's hereditary optic neuropathy: biochemical effect of 11778/ND4 and 3460/ND1 mutations and correlation with the mitochondrial genotype. Neurology, 1997, Volume: 48, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Blood Platelets; DNA, Mitochondrial; Family Health; Female; Furans; Genotype; Humans; Leukocytes; Male; Mitochondria; NADH, NADPH Oxidoreductases; Optic Atrophies, Hereditary; Pedigree; Phenotype; Point Mutation; Rotenone	1997
Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase). The Journal of biological chemistry, 1999, Jan-29, Volume: 274, Issue:5 Topics: Animals; Binding Sites; Cattle; Enzyme Inhibitors; Furans; Kinetics; Muscidae; NAD(P)H Dehydrogenase (Quinone); Pyridines; Pyrimidines; Quinazolines; Rotenone; Spectrometry, Fluorescence	1999
Biochemical features of mtDNA 14484 (ND6/M64V) point mutation associated with Leber's hereditary optic neuropathy. Annals of neurology, 1999, Volume: 45, Issue:3 Topics: Adult; Amino Acid Sequence; Blood Platelets; DNA, Mitochondrial; Female; Furans; Humans; Male; Methacrylates; Middle Aged; Molecular Sequence Data; Optic Atrophies, Hereditary; Pedigree; Point Mutation; Rotenone; Thiazoles	1999
NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone. Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-30, Volume: 96, Issue:7 Topics: Azirines; Benzoquinones; Electron Transport; Enzyme Inhibitors; Furans; Iron-Sulfur Proteins; Kinetics; Macromolecular Substances; NAD(P)H Dehydrogenase (Quinone); Paracoccus denitrificans; Photoaffinity Labels; Pyridazines; Pyridines; Rotenone; Thermus thermophilus; Tritium	1999
Inhibition of mitochondrial oxidative phosphorylation induces hyper-expression of glutamic acid decarboxylase in pancreatic islet cells. Autoimmunity, 1999, Volume: 30, Issue:1 Topics: Animals; Antimycin A; Arginine; Carboxin; Cells, Cultured; Cricetinae; Cytotoxins; Diabetes Mellitus, Type 1; Dopamine Antagonists; Furans; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Haloperidol; Image Processing, Computer-Assisted; Immunohistochemistry; Insulin; Islets of Langerhans; Mice; Mitochondria; Oxidative Phosphorylation; Phenylurea Compounds; Radioimmunoassay; Rodenticides; Rotenone; Uncoupling Agents	1999
Kinetic characterization of mitochondrial complex I inhibitors using annonaceous acetogenins. Archives of biochemistry and biophysics, 1999, Sep-01, Volume: 369, Issue:1 Topics: Animals; Cattle; Furans; Kinetics; Lactones; Mitochondria, Heart; NAD; NAD(P)H Dehydrogenase (Quinone); Plant Extracts; Rotenone; Submitochondrial Particles; Ubiquinone	1999
Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species. Biochimica et biophysica acta, 2009, Volume: 1787, Issue:5 Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Electron Transport Complex I; Furans; Hydrogen Peroxide; Insecticides; Kinetics; Mitochondria; Mitochondria, Heart; Protein Subunits; Pyridines; Reactive Oxygen Species; Rotenone; Submitochondrial Particles; Superoxide Dismutase; Ubiquinone	2009
Food derived respiratory complex I inhibitors modify the effect of Leber hereditary optic neuropathy mutations. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 120 Topics: Apoptosis; Capsaicin; Cell Line; DNA, Mitochondrial; Electron Transport Complex I; Enzyme Inhibitors; Food Analysis; Furans; Gene-Environment Interaction; Humans; Optic Atrophy, Hereditary, Leber; Oxidative Phosphorylation; Oxygen Consumption; Point Mutation; Rotenone; Xenobiotics	2018