Compounds > 4-fluorodeprenyl

Page last updated: 2024-09-03

4-fluorodeprenyl and selegiline

4-fluorodeprenyl has been researched along with selegiline in 9 studies

Compound Research Comparison

Studies (4-fluorodeprenyl)	Trials (4-fluorodeprenyl)	Recent Studies (post-2010) (4-fluorodeprenyl)	Studies (selegiline)	Trials (selegiline)	Recent Studies (post-2010) (selegiline)
10	0	2	2,575	319	394

Protein Interaction Comparison

Protein	Taxonomy	4-fluorodeprenyl (IC50)	selegiline (IC50)
Cholinesterase	Homo sapiens (human)		0.0055
Cytochrome P450 3A4	Homo sapiens (human)		0.0039
Alpha-2A adrenergic receptor	Homo sapiens (human)		1.798
Alpha-2B adrenergic receptor	Homo sapiens (human)		0.376
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)		0.2127
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)		0.9046
Amine oxidase [flavin-containing] A	Homo sapiens (human)		1.4408
Adenosine receptor A1	Rattus norvegicus (Norway rat)		0.0067
Amine oxidase [flavin-containing] B	Homo sapiens (human)		0.1001
Type-1 angiotensin II receptor	Sus scrofa (pig)		0.048
Alpha-synuclein	Homo sapiens (human)		0.27
Amine oxidase [flavin-containing] B	Bos taurus (cattle)		1
Sigma intracellular receptor 2	Rattus norvegicus (Norway rat)		0.017

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (77.78)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (22.22)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dewey, SL; Fowler, JS; Guillaume, M; Plenevaux, A; Wolf, AP	2
Dalló, J; Knoll, J	1
Knoll, J; Kummert, M; Sugár, J; Tóth, V	1
Heikkila, RE; Terleckyj, IA	1
Magyar, K	1
Cooper, T; Gaál, J; Hashim, A; Lajtha, A; Sershen, H	1
Kalász, H; Pöstényi, Z; Tekes, K; Tóth-Molnár, E	1
Amini, N; Catafau, AM; Fazio, P; Halldin, C; Hannestad, J; Heinrich, T; Kettschau, G; Leesch, S; Lehmann, L; Nag, S; Svedberg, M; Thiele, A; Varrone, A	1

Reviews

1 review(s) available for 4-fluorodeprenyl and selegiline

Article	Year
Behaviour of (-)-deprenyl and its analogues. Journal of neural transmission. Supplementum, 1994, Volume: 41 Topics: Animals; Blood; Brain; Monoamine Oxidase Inhibitors; Rats; Selegiline; Structure-Activity Relationship	1994

Other Studies

8 other study(ies) available for 4-fluorodeprenyl and selegiline

Article	Year
Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl and (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and positron emission tomography studies in baboon brain. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Brain; Carbon Radioisotopes; Corpus Striatum; Female; Indicators and Reagents; Isotope Labeling; Kinetics; Molecular Structure; Organ Specificity; Papio; Phenethylamines; Selegiline; Stereoisomerism; Structure-Activity Relationship; Tomography, Emission-Computed	1990
Effect of (-)-para-fluoro-deprenyl on survival and copulation in male rats. Acta physiologica Hungarica, 1992, Volume: 79, Issue:2 Topics: Animals; Copulation; Ejaculation; Longevity; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline	1992
(-)deprenyl and (-)parafluorodeprenyl-treatment prevents age-related pigment changes in the substantia nigra. A TV-image analysis of neuromelanin. Mechanisms of ageing and development, 1992, Volume: 63, Issue:2 Topics: Aging; Animals; Male; Melanins; Neurons; Pigmentation; Rats; Selegiline; Substantia Nigra	1992
In vivo and in vitro pharmacologic profile of two new irreversible MAO-B inhibitors: MDL 72,974A and fluorodeprenyl. Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648 Topics: Allyl Compounds; Animals; Brain; Butylamines; Isoenzymes; Mice; Monoamine Oxidase Inhibitors; Rats; Selegiline	1992
The synthesis of no-carrier-added DL-4-[18F]fluorodeprenyl via the nucleophilic aromatic substitution reaction. International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1991, Volume: 42, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Female; Fluorine Radioisotopes; Indicators and Reagents; Mice; Molecular Structure; Selegiline; Tissue Distribution	1991
Metabolism of (-)-deprenyl and PF-(-)-deprenyl in brain after central and peripheral administration. Neurochemical research, 1996, Volume: 21, Issue:10 Topics: Amphetamine; Animals; Brain; Corpus Striatum; Gas Chromatography-Mass Spectrometry; Injections, Subcutaneous; Male; Methamphetamine; Microdialysis; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selegiline; Sensitivity and Specificity	1996
HPLC analysis of blood-brain barrier penetration of 4-fluorodeprenyl. Journal of pharmaceutical and biomedical analysis, 2015, Volume: 102 Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Male; Rats; Rats, Wistar; Selegiline	2015
In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:2 Topics: Animals; Autoradiography; Blood Proteins; Carbon Radioisotopes; Fluorine Radioisotopes; Humans; Isotope Labeling; Macaca fascicularis; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Radiopharmaceuticals; Recombinant Proteins; Selegiline	2016