4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with piperidines in 419 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (7.16) | 18.7374 |
| 1990's | 210 (50.12) | 18.2507 |
| 2000's | 131 (31.26) | 29.6817 |
| 2010's | 46 (10.98) | 24.3611 |
| 2020's | 2 (0.48) | 2.80 |
| Authors | Studies |
|---|---|
| Kashima, K; Kataoka, K; Kato, M; Kuriyama, K; Ohkuma, S | 1 |
| Bolognesi, ML; Budriesi, R; Melchiorre, C; Minarini, A; Recanatini, M | 1 |
| Ishihara, H; Shimura, S | 1 |
| Abdallah, EA; Eldefrawi, AT; Eldefrawi, ME; Jett, DA | 1 |
| Akerman, KE; Hämäläinen, H; Heikkilä, J; Kukkonen, J; Näsman, J; Ojala, P | 1 |
| Buchan, AM; Kwok, YN; MacLeod, MD; Meloche, RM | 1 |
| Iwabuchi, Y; Masuhara, T | 1 |
| Barlow, RB; Bond, S; Holdup, DW; Howard, JA; McQueen, DS; Paterson, A; Veale, MA | 1 |
| Cazzola, M; Constantino, M; De Santis, D; Matera, MG; Rossi, F | 1 |
| Baughman, RW; Jones, KA | 1 |
| Aguilar, JS; Ballesta, JJ; Criado, M; Palmero, M; Reig, JA; Viniegra, S | 1 |
| Derksen, FJ; Robinson, NE; Wang, Z; Yu, M | 1 |
| Gabelt, BT; Kaufman, PL | 2 |
| Frey, KA; Howland, MM | 1 |
| Akerman, KE; Kukkonen, J | 1 |
| Hendriks, MG; Pfaffendorf, M; Van Zwieten, PA | 2 |
| Bungardt, E; Feifel, R; Lambrecht, G; Moser, U; Mutschler, E; Surprenant, A; Tacke, R; Vockert, E | 1 |
| Badini, I; Beani, L; Bianchi, C; Cintra, A; Fuxe, K; Siniscalchi, A | 1 |
| Martin, JR | 1 |
| Bloom, JW; Halonen, M; Mahesh, VK; Nunan, LM; Palmer, JD; Yamamura, HI | 1 |
| Camus, J; Christophe, J; Tastenoy, M; Waelbroeck, M | 1 |
| Blazynski, C; McIntosh, H | 1 |
| Bolofo, ML; Giles, H; Martin, GR | 1 |
| Barlow, RB; Christophe, J; Renzetti, AR; Tastenoy, M; Waelbroeck, M | 1 |
| Funakoshi, A; Jimi, A; Kono, A; Tateishi, K; Tsuru, M; Wakasugi, H | 1 |
| Anderson, DJ; Connolly, T; McKinney, M; Miller, JH; Vella-Rountree, L | 1 |
| Buyse, MA; Fraeyman, NH; Lefebvre, RA | 1 |
| Challiss, RA; Nahorski, SR; Whitham, EM | 1 |
| Courtney, MJ; Nicholls, DG | 1 |
| Bagetta, G; Constanti, A | 1 |
| Böhm, M; Erdmann, E; Gengenbach, S; Hauck, RW; Sunder-Plassmann, L | 1 |
| Cheung, CL; De Boer, T; Tonnaer, JA | 1 |
| Bindslev, N; Winding, B | 1 |
| Donetti, A; Giudici, L; Micheletti, R; Turconi, M | 1 |
| Donoff, B; Lad, R; Rangachari, PK | 1 |
| Alonso, MJ; Arribas, S; Balfagón, G; Marín, J; Salaices, M | 1 |
| Angeli, P; Brasili, L; Cingolani, ML; Marucci, G; Pigini, P; Tonnini, MC | 1 |
| Buxton, IL; Horowitz, B; Zhang, LB | 1 |
| Aikawa, T; Itabashi, S; Ohrui, T; Sasaki, H; Sekizawa, K; Takishima, T | 1 |
| Bouchenafa, O; Livingston, A | 1 |
| Araujo, DM; Lapchak, PA; Quirion, R | 1 |
| Chiba, S; Furukawa, Y; Nakane, T | 1 |
| Costa, G; Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Sajia, A | 1 |
| Low, PA; Torres, NE; Zollman, PJ | 1 |
| Hersey, SJ; Kajimura, M; Sachs, G; Scott, DR; Wilkes, JM | 1 |
| Angeli, P; Bianchi, S; Imeri, L; Mancia, M | 2 |
| Freschi, JE | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Rivera, L | 1 |
| Boselli, C; Kenakin, TP | 1 |
| Ballabeni, V; Barocelli, E; Impicciatore, M; Lavezzo, A; Morini, G | 1 |
| Barlow, RB; Shepherd, MK; Veale, MA | 1 |
| Chiba, S; Tsukada, M | 2 |
| Arruebo, MP; Bueno, L; Liberge, M | 1 |
| Buccafusco, JJ | 1 |
| Yang, CM | 1 |
| Baron, E; Boer, R; Eltze, M; Kromer, W | 1 |
| Bast, A; Doelman, CJ; Nagtegaal, JE; Rodrigues de Miranda, JF; Sprong, RC | 1 |
| Davidson, A; Matus-Leibovitch, N; Mengod, G; Oron, Y | 1 |
| Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Pompei, PL | 1 |
| Alger, BE; Pitler, TA | 1 |
| Li, AH; Nattie, EE | 1 |
| Elzinga, CR; Roffel, AF; Zaagsma, J | 1 |
| Harbon, S; Leiber, D; Marc, S | 1 |
| Fleming, N; Laniyonu, A; Sliwinski-Lis, E | 1 |
| Elzinga, CR; Meurs, H; Roffel, AF; Zaagsma, J | 1 |
| Bazzani, C; Bertolini, A; Guarini, S; Pasini, M; Tagliavini, S | 1 |
| Duckles, SP; Ehlert, FJ; Garcia-Villalon, AL; Krause, DN | 1 |
| Entzeroth, M; Mayer, N | 1 |
| Michel, AD; Whiting, RL | 1 |
| Akahane, K; Chiba, S; Furukawa, Y; Karasawa, Y | 1 |
| Coppes, RP; Meurs, H; Remie, R; Roffel, AF; Zaagsma, J | 1 |
| Barlow, RB; Harris, G; Holdup, DW; Veale, MA; Williams, A | 1 |
| Barnes, PJ; Mak, JC | 1 |
| Allen, TG; Burnstock, G | 1 |
| Alonso, R; Didier, M; Soubrie, P | 1 |
| Brichant, JF; Gunst, SJ; Rehder, K; Warner, DO | 1 |
| De Boer, P; Horn, AS; Rollema, H; Westerink, BH; Zaagsma, J | 1 |
| Louie, DS; Owyang, C | 1 |
| Flavahan, NA; Gunst, SJ; Stropp, JQ | 1 |
| Anderson, D; el-Fakahany, EE; Forray, C; McKinney, M | 1 |
| Amrhein, CL; el-Fakahany, EE; Forray, C; Surichamorn, W | 1 |
| Cazzola, M; Cenicola, ML; D'Amato, G; De Santis, D; Lisa, M; Maione, S; Marmo, E; Matera, MG | 1 |
| Chiba, S; Haruta, K; Homma, N; Horiuchi, A; Iwatsuki, K; Yonekura, H | 1 |
| Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E | 1 |
| Ghataorre, AS; Lambert, DG; Nahorski, SR | 1 |
| Barlow, RB; Johnson, O | 1 |
| Brown, DA; Marrion, NV; Marsh, SJ; Smart, TG | 1 |
| Dodds, WJ; Gilbert, RJ | 1 |
| Hsu, CT; Hyman, PE; Jing, J; Snape, WJ; Tomomasa, T | 1 |
| Delmendo, RE; Michel, AD; Whiting, RL | 1 |
| Camus, J; Christophe, J; Waelbroeck, M; Winand, J | 1 |
| Choo, LK; Mitchelson, F | 1 |
| Barlow, RB; Shepherd, MK; Tydeman, H; Veale, MA | 1 |
| Ruigt, GS; Tonnaer, JA; Van Wezenbeek, LA | 1 |
| Brezenoff, HE; Xiao, YF | 1 |
| Barnes, PJ; Mak, JC; McCormack, DG; Minette, P | 1 |
| Brezenoff, HE; Vargas, H; Xiao, YF | 1 |
| Davidesko, D; Doods, HN; Rinner, I; van Charldorp, KJ; van Zwieten, PA | 1 |
| Nilvebrant, L; Sparf, B | 1 |
| Davidesko, D; de Jonge, A; Doods, HN; Mathy, MJ; van Charldorp, KJ; van Zwieten, PA | 1 |
| Bitar, KN; Grider, JR; Makhlouf, GM | 1 |
| Gross, GJ; Pelc, LR; Warltier, DC | 1 |
| Barlow, RB; Shepherd, MK | 2 |
| Constanti, A; Sim, JA | 1 |
| Eglen, RM; Whiting, RL | 1 |
| Gilbert, R; Goyal, RK; Rattan, S | 1 |
| Haruta, K; Hori, H; Iguchi, A; Itoh, K; Matsubara, T; Nanki, M; Sakamoto, N; Uemura, K | 1 |
| Heilbronn, E; Järlebark, L; Lawoko, G | 1 |
| Chiba, S; Nakane, T; Ren, LM | 1 |
| Ernsberger, P; Evinger, MJ; Joh, TH; Regunathan, S; Reis, DJ | 1 |
| Bai, D; Sattelle, DB | 1 |
| Cooke, HJ; Javed, N; Reddix, R; Wang, YZ | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Baird, AW; Farrell, CB; O'Boyle, KM; O'Malley, KE | 1 |
| Francis, NJ; Grant, MP; Landis, SC | 1 |
| Kondo, S; Morita, T; Tashima, Y | 1 |
| Bolognesi, ML; Budriesi, R; Chiarini, A; Melchiorre, C; Recanatini, M; Sabatino, P; Tumiatti, V | 1 |
| Maggio, R; Nanavati, S; Vogel, Z; Wess, J | 1 |
| Burgard, EC; Cote, TE; Sarvey, JM | 1 |
| Nakamura, K; Okuma, Y; Osumi, Y; Yokotani, K | 1 |
| DeSautel, MG; Maher, JW; Sandler, AD; Schlegel, JF | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Fukui, H; Inagaki, N; Kondou, H | 1 |
| Hayakawa, T; Kitagawa, M; Kondo, T; Naruse, S; Shibata, T; Tanikawa, M | 1 |
| Howell, RE; Kovalsky, MP | 1 |
| Brown, MC; Liberman, MC; Sewell, WF; Sridhar, TS | 1 |
| Corrêa, FM; Peres-Polon, VL | 1 |
| Imaizumi, Y; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Ballabeni, V; Barocelli, E; Caretta, A; Chiavarini, M; Impicciatore, M; Molina, E | 1 |
| Cynader, MS; Drance, SM; Gupta, N; McAllister, R; Prasad, S; Rootman, J | 1 |
| Howell, RE; Kovalsky, MP; Laemont, KD | 1 |
| Ko, FN; Lin, CH; Teng, CM; Wu, YC; Yang, CM | 1 |
| DelValle, J; Park, J; Yamada, T; Yokotani, K | 1 |
| Furukawa, T; Katsuragi, T; Soejima, O | 1 |
| Bissonnette, BM; Brasitus, TA; Khare, S; Sitrin, MD; Tien, XY; Wali, RK; Wilson, D | 1 |
| Fehér, E; Matkó, I; Vizi, ES | 1 |
| Abe, K; Mizutani, A; Nakata, A; Saito, H | 1 |
| Eglen, RM; Watson, N | 1 |
| Croom, WJ; Hagler, WM; Harmon, DL; Krehbiel, CR; St Jean, G; Walker, JA | 1 |
| Abysique, A; Blanquet, F; Gonella, J | 1 |
| Deirmengiant, C; Maslanski, JA; Patelt, J; Powelt, R | 1 |
| Dauphin, F; Hamel, E; Linville, DG | 1 |
| Bobbin, RP; Erostegui, C; Norris, CH | 1 |
| Davenport, TA; Fukumoto, Y; Gousse, A; Kamai, T; Latifpour, J; Weiss, RM; Yoshida, M | 1 |
| Blüml, K; Mutschler, E; Wess, J | 1 |
| Cynader, M; Gu, Q; Jia, W; Liu, Y | 1 |
| Delbro, DS; Gustafsson, BI | 1 |
| Randall, WC; Wurster, RD; Xi-Moy, SX | 1 |
| Dobbie, JW; Duffield, R; Hjelle, JT; Ho, AK; Steidley, KR | 1 |
| Baghdoyan, HA; Carlson, BX; Roth, MT | 1 |
| Buccafusco, JJ; Holland, LN; Shuster, LC | 1 |
| Fukomoto, Y; Latifpour, J; Weiss, RM; Yoshida, M | 1 |
| Chen, FF; Hsu, HF; Sung, TC; Wu, D; Yang, CM | 1 |
| Chuang, DM; Fukamauchi, F; Hough, C; Saunders, PA | 1 |
| Vanner, S | 2 |
| Hootman, SR; Kovalcik, SA; Zukerman, J | 1 |
| Gies, JP; Haddad, EB; Landry, Y; Trifilieff, A | 1 |
| Wills-Karp, M | 1 |
| Maggio, R; Vogel, Z; Wess, J | 1 |
| Chen, J; Feldmann, BJ; Woldemussie, E | 1 |
| Frey, KA; Zubieta, JK | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Cosentino, M; Crema, A; D'Angelo, L; de Ponti, F; Einaudi, A; Frigo, GM; Lecchini, S | 1 |
| Collins, D; Messer, WS; Smith, DA | 1 |
| Tonnaer, JA; van Huizen, F | 1 |
| Manjeet, S; Sim, MK | 1 |
| Shiraishi, K; Takayanagi, I | 1 |
| Garssen, J; Gierveld, CM; Nijkamp, FP; Van der Vliet, H; Van Loveren, H | 1 |
| Gean, PW; Hsu, KS; Huang, CC | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
| Berrio, LF; Chapa, AM; Croom, WJ; Fernandez, JM; Hagler, WM; Tempelman, RJ; Thompson, DL | 1 |
| Asano, T; Ito, S; Nakazato, Y; Ohta, T; Otsuguro, K | 1 |
| Chuang, DM; Hough, CJ; Saunders, PA | 1 |
| Chang, B; Melvin, JE; Zhang, GH | 1 |
| Haddad, EB; Khawaja, AM; Mak, JC; Ramnarine, SI; Rogers, DF | 1 |
| de la Vega, MT; Montano, JA; Nunez, A | 1 |
| Aceves, J; Flores, G; Hernández-López, S; Martínez-Fong, D; Rosales, MG; Sierra, A | 1 |
| Eglen, RM; Reddy, H; Watson, N | 1 |
| Tobin, G | 1 |
| McCaffrey, TV; Yang, B | 1 |
| Acs, Z; Makara, GB; Pintér, I | 1 |
| Adachi, S; Koike, K; Takayanagi, I | 1 |
| Ehlert, FJ; Ostrom, RS | 1 |
| Culp, DJ; Latchney, LR; Luo, W; Richardson, LA; Watson, GE | 1 |
| Buchan, AM; Koop, I; Meloche, RM; Squires, PE | 1 |
| Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L | 1 |
| Onoe, H; Sakai, K | 1 |
| Murayama, T; Nomura, Y; Yamada, T | 1 |
| Aronstam, RS; Puhl, HL; Raman, PS; Williams, CL | 1 |
| Cheng, JT; Hung, YC; Lin, SN; Tong, YC | 1 |
| Haga, N; Itoh, Z; Mizumoto, A; Satoh, M; Yamada, T | 1 |
| Koss, MC | 1 |
| Bouwer, J; Paans, AM; Vaalburg, W; van Waarde, A; Visser, GM; Visser, TJ | 1 |
| Levin, RJ; Przyborski, SA | 1 |
| Semba, K; White, TD | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Tomasini, C | 1 |
| Arias-Montaño, JA; de la Vega, MT; Nuñez, A | 1 |
| Bolton, TB; Zholos, AV | 1 |
| Ehlert, FJ; Sawyer, GW | 1 |
| Ahrén, B; Karlsson, S; Sundler, F | 1 |
| Alfonzo, MJ; de Alfonzo, RG; de Becemberg, IL; de Herrera, VN; de Villaroel, SS; Misle, AJ | 1 |
| Goodman, HM; McCullough, JR; Mitra, S; Ugur, M; Ugur, O; Yamaguchi, H | 1 |
| Go, ML; Sim, MK; Xu, R | 1 |
| Cobuzzi, A; Lai, FM; Spinelli, W | 1 |
| Komori, S; Nakayama, T; Ohashi, H; Unno, T | 1 |
| Laurier, LG; Preiksaitis, HG | 1 |
| Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M | 1 |
| Blumenthal, JA; Carey, HV; Onorato, JJ | 1 |
| Bégos, A; Bizot, JC; Breton, P; Brochet, D; Tambuté, A; Trovero, F | 1 |
| Galas, L; Garnier, M; Lamacz, M; Lenglet, S; Tonon, MC; Vaudry, H | 1 |
| Chew, CS; Flemström, G; Säfsten, B | 1 |
| Johnson, IT; Lindqvist, SM; Satoh, Y; Sharp, P; Williams, MR | 1 |
| Chen, HI; Liao, YL | 1 |
| Chen, H; Cheng, L; Hsu, L; Jen, CJ; Lin, MT; Yang, C | 1 |
| Inadome, A; Kawano, T; Miyamoto, Y; Seshita, H; Takahashi, W; Ueda, S; Yono, M; Yoshida, M | 1 |
| Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A | 1 |
| Braverman, A; Legos, J; Luthin, G; Ruggieri, M; Young, W | 1 |
| Rivers, RJ | 1 |
| Wallis, RM | 1 |
| Ehlert, FJ; Thomas, EA | 1 |
| Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J | 1 |
| Damer, V; Krichevsky, VP; Pagala, MK; Vaydovsky, I; Wise, GJ | 1 |
| Lu, Y; Shi, H; Wang, H; Wang, Z; Yang, B | 2 |
| Erickson, KA; Schroeder, A; Zhang, X | 1 |
| Pagano, AP; Parkman, HP; Ryan, JP | 1 |
| Braverman, AS; Ruggieri, MR | 1 |
| Shi, H; Wang, H; Wang, Z | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Goldie, RG; Preuss, JM | 1 |
| Corrêa, FM; Crippa, GE; Kuboyama, RH; Peres-Polon, VL | 1 |
| Acs, Z; Makara, GB; Némethy, Z | 1 |
| Baghdoyan, HA; Lydic, R | 1 |
| Arellano, RO; Garay, E; Miledi, R | 1 |
| Fischer, LG; Hahnenkamp, K; Horstman, DJ; Kechner, NE; Rich, GF | 1 |
| Elhusseiny, A; Hamel, E | 1 |
| Feldman, JL; Shao, XM | 1 |
| Fitzgerald, ME; Reiner, A; Zagvazdin, Y | 1 |
| Harada, A; Honda, K; Kamiya, H; Takano, Y | 1 |
| Halayko, AJ; Kahraman, S; Mitchell, RW; Solway, J; Wylam, ME | 1 |
| Iannazzo, L; Majewski, H | 1 |
| Smith, PG; Steinle, JJ | 1 |
| Malomough, A; Naumenko, N; Nikolsky, E; Urazaev, A; Vyskocil, F | 1 |
| Zhao, D; Zhou, ZJ | 1 |
| Levendusky, M; Longhurst, PA | 1 |
| Bourreau, JP; Huang, Y; Shen, S | 1 |
| Kim, D; Moore, BA; Vanner, S | 1 |
| Krysiak, PS; Laurier, LG; Preiksaitis, HG; Sims, SM; Wang, J | 1 |
| Chapple, CR; Chess-Williams, R; Yamanishi, T; Yasuda, K | 2 |
| Bender, K; Biewald, A; Eickel, A; Meyer, T; Pott, L; Wellner-Kienitz, MC | 1 |
| Fushimi, T; Masuda, T; Saitoh, H; Shimura, S; Shirato, K | 1 |
| Hashimoto, S; Iwanaga, S; Makita, T; Saito, M; Shibata, O; Sumikawa, K; Tsuda, A | 1 |
| Chapple, CR; Chess-Williams, R; Couldwell, C; Sellers, DJ; Yamanishi, T; Yasuda, K | 1 |
| Kwon, SC | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Kadota, H; Kuwahara, M; Mikami, H; Nishibata, R; Tsubone, H | 1 |
| Franco, W; Leite, RS | 1 |
| Gregard, A; Hedemann, MS; Kruszewska, D; Laerke, HN; Lesniewska, V; Pierzynowski, SG; Weström, B | 1 |
| Choppin, A; Eglen, RM | 1 |
| Havlas, Z; Lysíková, M; Tucek, S | 1 |
| Avellar, MC; Guaze, EF; Maróstica, E; Porto, CS | 1 |
| Delbro, DS; Giglio, D; Tobin, G | 2 |
| Gerthoffer, WT; Singer, CA; Vang, S | 1 |
| Chao, HJ; Chen, SF; Hsueh, CM; Lin, RJ | 1 |
| Pérez Leirós, C; Rosignoli, F | 1 |
| Kato, T; Ogasawara, M; Sato, K; Shimoda, N; Sugaya, K | 1 |
| Benoit, JN; Cohen, MV; Downey, JM; Oldenburg, O; Qin, Q; Sharma, AR | 1 |
| Advenier, C; Cortijo, J; Molimard, M; Morcillo, EJ; Moreau, J; Naline, E; Sarria, B; Therond, P; Zhang, Y | 1 |
| Giglio, D; Götrick, B; Tobin, G | 1 |
| Chen, JT; Hsu, JH; Hsu, SF; Liou, SS; Liu, IM; Wu, YC | 1 |
| Addison, S; Evangelista, S; Greer, S; Hernon, J; Johns, N; Johnson, I; Lewis, M; Lindqvist, S; Mackay, J; Rhodes, M; Sharp, P; Speakman, C; Stebbings, W; Tighe, R; Watson, M; Williams, M | 1 |
| Albuquerque, EX; Aracava, Y; Castro, NG; Fawcett, WP; Pereira, EF; Randall, WR; Santos, MD | 1 |
| Fukumori, R; Goshima, Y; Hagiwara, Y; Kanaya, T; Kubo, T; Okatani, H | 2 |
| Gosens, R; Grootte Bromhaar, MM; McKay, S; Meurs, H; Nelemans, SA; Zaagsma, J | 1 |
| Das, S; Murthy, KS; Zhou, H | 1 |
| Chen, QW; Li, HW; Liu, Y; Ma, ML; Wang, Y; Yang, BF; Zhang, Y | 1 |
| de Groat, WC; Rocha, JN; Smith, CP; Somogyi, GT; Yoshiyama, M; Zernova, GV | 1 |
| Arredondo, J; Chernyavsky, AI; Grando, SA; Ndoye, A; Nguyen, VT; Wess, J; Zia, S | 1 |
| Choi, KH; Jeon, JH; Kang, TM; Kim, HJ; Kim, IG; Kim, KW; Kim, SJ; Min, KW; Park, KH; So, I; Yang, DK | 1 |
| Farnbauch, LJ; Robertson, KL; Rowland, NE | 1 |
| Emala, CW; Hirshman, CA; Jooste, E; Klafter, F | 1 |
| Evilevitch, L; Pierzynowski, SG; Weström, BR | 1 |
| Abe, K; Chikuma, T; Hojyo, H; Kato, M; Miyatake, T; Taguchi, K; Utsunomiya, I | 1 |
| Bernardino, CR; Chang, EL; Dartt, DA; Hodges, RR; Horikawa, Y; Rios, JD; Rubin, PA; Shatos, MA; Zoukhri, D | 1 |
| Borda, E; Busch, L | 1 |
| Honda, E; Inenaga, K; Kawano, H; Masuko, S; Ono, K; Toyono, T | 1 |
| Bordi, F; Costa, LG; Dieguez-Acuña, FJ; Guizzetti, M; Madia, F; Vitalone, A; Woods, JS | 1 |
| Reed, DE; Vanner, SJ | 1 |
| Callaghan, B; Keef, KD; Koh, SD | 1 |
| Michel, FJ; Robillard, JM; Trudeau, LE | 1 |
| Harada, N; Makita, T; Niwa, M; Saito, M; Shibata, O; Sumikawa, K; Yamaguchi, M; Yoshimura, M | 1 |
| Crowell, MD; James, AN; Parkman, HP; Ryan, JP | 1 |
| Mamiya, T; Okuda, A; Ukai, M | 1 |
| Crittenden, EL; García, DM; González, A | 1 |
| Bindslev, N; Hansen, MB; Larsen, R; Mertz-Nielsen, A | 1 |
| Jing, YH; Li, HL; Liu, Y; Sun, HL; Yang, BF | 1 |
| Ani, DV; Paulose, CS; Renuka, TR | 1 |
| Ehlert, FJ; Griffin, MT; Hsu, JC; Lee, AG; Leung, K; Shehnaz, D | 1 |
| Chen, LB; Liu, CY; Liu, KJ; Wang, PS; Xie, DP; Zhang, CL | 1 |
| Doi, Y; Hayashi, H; Kaibara, M; Murasaki, O; Taniyama, K; Uezono, Y; Yano, K | 1 |
| Ando, S; Harasawa, I; Honda, K; Kamiya, HO; Koga, K; Takano, Y | 1 |
| Diamant, NE; Gaisano, HY; Muinuddin, A; Naqvi, K; Sheu, L | 1 |
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| Dong, DL; Jiao, JD; Liu, Y; Wang, HZ; Xu, CQ; Yang, BF | 1 |
| Osadchiĭ, OE | 2 |
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| Dodds, C; Mitrani, P; Patel, MS; Srinivasan, M | 1 |
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| Borda, E; De Couto Pita, A; Orman, B; Reina, S; Sterin-Borda, L | 1 |
| Andersson, M; Aronsson, P; Delbro, DS; Giglio, D; Haraldsson, B; Tobin, G | 1 |
| Cunnane, TC; Cuprian-Beltechi, AM; Solanki, P | 1 |
| Bonanno, A; Ferraro, M; Gjomarkaj, M; Montalbano, AM; Pieper, MP; Pompeo, F; Profita, M; Riccobono, L; Siena, L | 1 |
| Cheng, JT; Liu, IM; Liu, KY; Wu, YC; Yu, WC | 1 |
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| Chen, CP; Esiri, MM; Francis, PT; Lai, MK; Tsang, SW; Wong, PT | 1 |
| Gibina, AE; Salman, MA; Zefirov, AL; Zefirov, TL; Ziyatdinova, NI | 1 |
| Chaiyaroj, SC; Parkpian, P; Satayavivad, J; Suriyo, T; Thiantanawat, A | 1 |
| Chen, H; Chen, YH; Li, J; Li, L; Liang, L; Liu, X; Liu, Y; Ma, J; Peng, L; Qi, J; Wu, X; Xiao, J; Xu, J; Yang, Y; Zhang, Y; Zhao, C | 1 |
| Boone, TB; Lai, HH; Munoz, A; Smith, CP; Somogyi, GT; Szigeti, GP | 1 |
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| Pan, GP; Sun, LH; Wang, L; Yang, BF; Zhang, GX; Zhang, YL | 1 |
| Du, ZM; Gao, Y; Li, DL; Liu, Y; Lu, YJ; Sun, HL; Wang, LY; Wang, YP; Yang, BF | 1 |
| Bae, H; Choi, SM; Kim, HN; Kim, SK; Koo, S; Min, BI; Park, JH; Sun, B | 1 |
| Aydin, B; Cabadak, H; Kan, B; Küçükibrahimoğlu, E; Zafer Gören, M | 1 |
| Cueva-Rolón, R; Gómez-Martínez, LE | 1 |
| Choi, S; Choi, SJ; Jun, JY; Kim, SH; Parajuli, SP; So, KY; Sohn, HM; Yeum, CH; Yoon, PJ | 1 |
| Cunnane, TC; Cuprian-Beltechi, AM; Solanki, P; Teramoto, N | 1 |
| Li, N; Sun, DW; Zhang, QG; Zhou, R; Zhu, FG | 1 |
| Asari, T; Kusama, H; Maruyama, K | 1 |
| Chen, LP; Chen, W; Han, HM; Li, DL; Liu, Y; Pan, ZY; Qi, HP; Sun, HL; Wang, LY; Xie, J; Zhao, WM | 1 |
| Cohen, S; Del Galdo, F; DiMarino, AJ; Jimenez, SA; Mehendiratta, V; Rattan, S; Singh, J | 1 |
| Burbank, N; Calles-Escandon, J; Clark, PB; Elster, AW; Gage, HD; Garg, P; Garg, S; Kraas, J; Morton, K; Plaza, MJ; Wagner, JD | 1 |
| Cheng, JT; Ling, SM; Tsao, CW; Yang, TT | 1 |
| Gu, T; Iwakami, S; Minakata, K; Murakami, A; Ohashi, R; Tajima, K; Takahashi, K; Togo, S; Xie, C; Zhang, J; Zhang, S | 1 |
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| Jiang, X; Qin, Z; Tao, J; Wang, F; Wang, J; Zhang, L; Zhang, Y | 1 |
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| Britton, FC; Koh, SD; O'Driscoll, K; Sanders, KM; Sung, IK; Sung, TS; Zheng, H; Zhu, MH | 1 |
| Barnes, PJ; Brown, SM; Chana, KK; Donnelly, LE; Fenwick, PS; Koarai, A; Nicholson, AG; Russell, RE; Traves, SL | 1 |
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| Ishii, K; Makita, T; Nishioka, K; Shibata, O; Sumikawa, K; Tsuda, A | 1 |
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| Abramochkin, DV; Nikolsky, EE; Nurullin, LF; Sukhova, GS; Tapilina, SV | 1 |
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| Chen, HZ; Cui, YY; Hou, LN; Xu, GN; Xu, ZP; Yang, K; Zhang, WH; Zhu, L | 1 |
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| Barnes, PJ; Brown, SM; Donnelly, LE; Koarai, A; Nicholson, AG; Sturton, RG | 1 |
| Abramochkin, DV; Sukhova, GS; Tapilina, SV | 1 |
| Arrighi, N; Bodei, S; Cosciani Cunico, S; Michel, MC; Sigala, S; Simeone, C; Spano, P; Zani, D | 1 |
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| Chen, HZ; Cui, YY; Hou, LN; Song, Y; Tang, YB; Xu, ZP; Yang, K; Yu, ZH; Zhou, W; Zhu, L | 1 |
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| Chen, WJ; Dean, B; Lai, CY; Scarr, E; Thomas, N | 1 |
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| Chang, CH; Chen, KC; Chen, MC; Chiu, KY; Chiu, TH; Hsieh, JT; Lai, CH; Li, YH; Liao, WL; Lin, H; Oner, M; Teng, CJ; Wang, HY; Wu, CC; Yang, TY; Yu, CR; Yu, WC; Yue, CH | 1 |
| Ashpole, NM; Carvalho, FS; Castro, CH; Costa, EA; Fajemiroye, JO; Franco, OL; Lião, LM; Menegatti, R; Mourão, AA; Oliveira-Silva, I; Pedrino, GR; Silva, ON; Verli, H; Villavicencio, B; Xavier, CH | 1 |
| Murakami, M; Narita, T; Qi, B; Sugiya, H | 1 |
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4 review(s) available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and piperidines
| Article | Year |
|---|---|
The influence of the muscarinic receptor subtypes on the sleep-wake cycle.
Topics: Animals; Diamines; Humans; Parasympatholytics; Piperidines; Receptors, Muscarinic; Sleep | 1993 |
Functional role of M2 muscarinic receptors in the guinea pig ileum.
Topics: Animals; Colforsin; Cyclic AMP; Guinea Pigs; Heart; Histamine; Ileum; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pertussis Toxin; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Submandibular Gland; Virulence Factors, Bordetella | 1995 |
[Advances in the study of cardiac M3 receptor as a novel target of antiarrhythmic drugs].
Topics: Animals; Delayed Rectifier Potassium Channels; Humans; Membrane Potentials; Myocardial Ischemia; Pilocarpine; Piperidines; Receptor, Muscarinic M3; Signal Transduction | 2006 |
Secretion from acinar cells of the exocrine pancreas: role of enteropancreatic reflexes and cholecystokinin.
Topics: Animals; Cholecystokinin; Dogs; Guinea Pigs; Humans; Mice; Pancreas, Exocrine; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Cholecystokinin; Reflex; Vagus Nerve | 2009 |
1 trial(s) available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and piperidines
| Article | Year |
|---|---|
Pre-clinical and clinical pharmacology of selective muscarinic M3 receptor antagonists.
Topics: Animals; Atrial Function; Atropine; Colon; Dicyclomine; Dioxoles; Dogs; Drug Evaluation, Preclinical; Gastrointestinal Motility; Guinea Pigs; Heart Atria; Humans; Ileum; Male; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Rabbits; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivary Glands; Trachea; Vas Deferens | 1995 |
414 other study(ies) available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and piperidines
| Article | Year |
|---|---|
Characterization of muscarinic receptor subtypes on rat pancreatic acini: pharmacological identification by secretory responses and binding studies.
Topics: Amylases; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Male; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sincalide | 1992 |
Affinity and selectivity at M2 and M3 muscarinic receptor subtypes of cyclic and oxygenated analogues of 4-DAMP.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Piperidines; Receptors, Muscarinic; Sympatholytics | 1992 |
[The role of muscarinic receptor subtypes in feline tracheal submucosal gland secretion].
Topics: Animals; Atropine; Calcium; Cats; Electrolytes; Glycoproteins; In Vitro Techniques; Mucous Membrane; Piperidines; Pirenzepine; Receptors, Muscarinic; Second Messenger Systems; Trachea | 1992 |
Differential effects of paraoxon on the M3 muscarinic receptor and its effector system in rat submaxillary gland cells.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cyclic AMP; Hydrolysis; Male; Paraoxon; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Regression Analysis; Submandibular Gland | 1992 |
Muscarinic receptor subtypes in human neuroblastoma cell lines SH-SY5Y and IMR-32 as determined by receptor binding, Ca++ mobilization and northern blotting.
Topics: Blotting, Northern; Calcium; Humans; N-Methylscopolamine; Neuroblastoma; Phosphatidylinositols; Piperidines; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Tumor Cells, Cultured | 1992 |
Muscarinic regulation of somatostatin release from primary cultures of human antral epithelial cells.
Topics: Adult; Carbachol; Cells, Cultured; Epithelium; Female; Humans; Male; Methacholine Chloride; Parasympatholytics; Piperidines; Pyloric Antrum; Radioimmunoassay; Receptors, Muscarinic; Somatostatin | 1992 |
Effects of cholinergic and adrenergic agonists on the secretion of fluid and protein by submandibular glands of the hamster and the rat.
Topics: Animals; Cricetinae; Isoproterenol; Male; Mesocricetus; Metoprolol; Parasympathomimetics; Phenylephrine; Pilocarpine; Piperidines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Saliva; Salivary Proteins and Peptides; Submandibular Gland; Sympathomimetics | 1992 |
The contribution of charge to affinity at functional (M3) muscarinic receptors in guinea-pig ileum assessed from the effects of the carbon analogue of 4-DAMP methiodide.
Topics: Animals; Cyclohexanes; Guinea Pigs; Ileum; In Vitro Techniques; Piperidines; Receptors, Muscarinic; Structure-Activity Relationship | 1992 |
Responsiveness and sensitivity to cholinergic agonists and antagonists in bovine isolated bronchial muscle.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Cattle; Gallamine Triethiodide; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine | 1992 |
Muscarinic M3 receptors inhibit a leak conductance in rat corticocallosal neurons.
Topics: Acetylcholine; Animals; Cells, Cultured; Cerebral Cortex; Corpus Callosum; Electrophysiology; Microspheres; Neurons; Piperidines; Pirenzepine; Potassium Channels; Rats; Receptors, Muscarinic | 1992 |
Muscarinic receptor subtypes in bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Binding Sites; Binding, Competitive; Cattle; Cell Membrane; Dicyclomine; Muscarine; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1992 |
Muscarinic receptor subtypes in equine tracheal smooth muscle.
Topics: Acetylcholine; Animals; Electric Stimulation; Gallamine Triethiodide; Horses; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1992 |
Inhibition of outflow facility and accommodative and miotic responses to pilocarpine in rhesus monkeys by muscarinic receptor subtype antagonists.
Topics: Accommodation, Ocular; Animals; Aqueous Humor; Female; Intraocular Pressure; Macaca mulatta; Male; Miosis; Muscarinic Antagonists; Parasympatholytics; Phenylephrine; Pilocarpine; Piperidines; Pirenzepine; Pupil | 1992 |
Quantitative autoradiography of muscarinic cholinergic receptor binding in the rat brain: distinction of receptor subtypes in antagonist competition assays.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Male; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine | 1992 |
Apparent noncompetitive antagonism of muscarinic receptor mediated Ca2+ mobilization by some muscarinic antagonists.
Topics: Atropine; Calcium; Fura-2; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1992 |
Characterization of the muscarinic receptor subtype mediating vasodilation in the rat perfused mesenteric vascular bed preparation.
Topics: Animals; Atropine; Benzodiazepinones; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Methacholine Chloride; Parasympatholytics; Perfusion; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Vasodilation | 1992 |
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arterioles; Benzodiazepinones; Carbachol; Guinea Pigs; Ileum; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandin Endoperoxides, Synthetic; Receptors, Muscarinic; Vasodilation | 1992 |
Muscarinic modulation of acetylcholine release from slices of guinea pig nucleus basalis magnocellularis.
Topics: Acetylcholine; Animals; Atropine; Calcium; Choline; Female; Guinea Pigs; Male; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Receptors, Muscarinic; Substantia Innominata; Tetrodotoxin | 1992 |
Pressor response to posterior hypothalamic administration of carbachol is mediated by muscarinic M3 receptor.
Topics: Animals; Atropine Derivatives; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Hypothalamus, Posterior; Kinetics; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Trachea | 1992 |
Binding properties of nine 4-diphenyl-acetoxy-N-methyl-piperidine (4-DAMP) analogues to M1, M2, M3 and putative M4 muscarinic receptor subtypes.
Topics: Allosteric Regulation; Animals; Corpus Striatum; In Vitro Techniques; Male; Myocardium; N-Methylscopolamine; Neuroblastoma; Pancreas; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Temperature; Tumor Cells, Cultured | 1992 |
Muscarinic receptor stimulated GTPase activity in synaptic membranes from bovine retina.
Topics: Animals; Cattle; Chromatography, Thin Layer; Diamines; Dose-Response Relationship, Drug; GTP Phosphohydrolases; Guanosine Triphosphate; Muscarinic Antagonists; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Retina; Stimulation, Chemical; Synaptic Membranes | 1992 |
Inhibition of endothelium-dependent vasorelaxation by arginine analogues: a pharmacological analysis of agonist and tissue dependence.
Topics: Acetylcholine; Alkylation; Animals; Aorta, Thoracic; Arginine; Glyburide; In Vitro Techniques; Indomethacin; Jugular Veins; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Parasympatholytics; Piperidines; Rabbits; Receptors, Muscarinic; Receptors, Serotonin; Serotonin Antagonists | 1992 |
Inactivation of brain cortex muscarinic receptors by 4-diphenylacetoxy-1-(2-chloroethyl) piperidine mustard.
Topics: Animals; Carbachol; Cerebral Cortex; Diphenylacetic Acids; Muscarinic Antagonists; Myocardium; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Acetylcholine regulates pancreastatin secretion from the human pancreastatin-producing cell line (QGP-1N).
Topics: Acetylcholine; Adenoma, Islet Cell; Atropine; Calcimycin; Calcium; Carbachol; Chromogranin A; Gastrin-Releasing Peptide; Humans; Pancreatic Hormones; Pancreatic Neoplasms; Parasympatholytics; Peptides; Piperidines; Pirenzepine; Receptors, Muscarinic; Sincalide; Tumor Cells, Cultured | 1991 |
Pharmacological profiles for rat cortical M1 and M2 muscarinic receptors using selective antagonists: comparison with N1E-115 muscarinic receptors.
Topics: Animals; Cerebral Cortex; Cyclic AMP; Diamines; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Phenethylamines; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
Study of the muscarinic receptor subtypes in N1E 115 mouse neuroblastoma cells.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Indicators and Reagents; Ligands; Mice; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cerebellum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Parasympatholytics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Cycloleucine; Cytoplasm; Ibotenic Acid; Kinetics; N-Methylaspartate; Neurotoxins; Piperidines; Quisqualic Acid; Receptors, Neurotransmitter | 1991 |
Muscarinic inhibition of excitatory neurotransmission in guinea-pig olfactory cortex slices: weak antagonism by M3-muscarinic receptor antagonists.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Parasympatholytics; Piperidines; Receptors, Muscarinic; Synaptic Transmission | 1991 |
Beta-adrenergic receptors and m-cholinergic receptors in human lung. Findings following in vivo and in vitro exposure to the beta-adrenergic receptor agonist, terbutaline.
Topics: Aged; Aged, 80 and over; Airway Obstruction; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lung; Middle Aged; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Cholinergic; Terbutaline | 1991 |
cGMP formation and phosphoinositide turnover in rat brain slices are mediated by pharmacologically distinct muscarinic acetylcholine receptors.
Topics: Animals; Atropine; Brain; Carbachol; Cyclic GMP; Guanylate Cyclase; Hippocampus; Inositol Phosphates; Male; Nitroprusside; Phosphatidylinositols; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Succinimides | 1991 |
Characterization of a muscarinic receptor controlling Cl- secretion in hen trachea.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bumetanide; Calcium Channels; Chickens; Chlorides; Dicyclomine; Female; In Vitro Techniques; Ion Channels; Kinetics; Mucous Membrane; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
4-DAMP analogues reveal heterogeneity of M1 muscarinic receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Duodenum; In Vitro Techniques; Isotonic Contraction; Male; Muscle Relaxation; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Vas Deferens | 1990 |
Functional subtyping of muscarinic receptors on canine esophageal mucosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Amiloride; Animals; Atropine; Carbachol; Chlorides; Dogs; Electric Conductivity; Esophagus; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mucous Membrane; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Sodium | 1991 |
Presynaptic M2-muscarinic receptors on noradrenergic nerve endings and endothelium-derived M3 receptors in cat cerebral arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Cats; Cerebral Arteries; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation | 1991 |
Pharmacological characterization of muscarinic receptor subtypes in rabbit isolated tissue preparations.
Topics: Animals; Aorta, Thoracic; Atropine; Diamines; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vas Deferens; Vasodilation | 1991 |
Muscarinic receptors in canine colonic circular smooth muscle. I. Coexistence of M2 and M3 subtypes.
Topics: Animals; Binding, Competitive; Cells, Cultured; Colon; Dogs; Female; GTP-Binding Proteins; Male; Membranes; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Tritium | 1991 |
Pre- and postjunctional muscarinic receptor subtypes in dog airways.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1991 |
The autoradiographic binding of [3H] quinuclidinyl benzilate to muscarinic receptors in the spinal cord of the sheep.
Topics: Animals; Autoradiography; Ligands; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine; Sheep; Spinal Cord | 1991 |
Heterogeneous binding of [3H]4-DAMP to muscarinic cholinergic sites in the rat brain: evidence from membrane binding and autoradiographic studies.
Topics: Animals; Autoradiography; Binding Sites; Brain; Ligands; Male; Membranes; Piperidines; Pirenzepine; Prosencephalon; Rats; Receptors, Muscarinic; Tissue Distribution; Tritium | 1991 |
Anti-muscarinic effect of alinidine on acetylcholine-induced vasodilation in isolated and perfused dog coronary arteries.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Parasympatholytics; Piperidines; Pirenzepine; Vasodilation | 1991 |
The release of atrial natriuretic factor induced by central carbachol injection may be mediated by muscarinic M1 receptors.
Topics: Animals; Atrial Natriuretic Factor; Brain; Carbachol; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Characterization of muscarinic receptor subtype of rat eccrine sweat gland by autoradiography.
Topics: Animals; Atropine; Autoradiography; Binding, Competitive; Eccrine Glands; Kinetics; Male; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tritium | 1991 |
Muscarinic responses of gastric parietal cells.
Topics: Aminopyrine; Animals; Arachidonic Acids; Calcium; Carbachol; Glucose; Image Processing, Computer-Assisted; Ionomycin; N-Methylscopolamine; Parasympatholytics; Parietal Cells, Gastric; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1991 |
Differential effects of M2 and M3 muscarinic antagonists on the sleep-wake cycle.
Topics: Animals; Cerebral Ventricles; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Reference Values; Sleep; Sympatholytics; Wakefulness | 1991 |
The effect of subtype-selective muscarinic receptor antagonists on the cholinergic current in motoneurons of the lobster cardiac ganglion.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Ganglia; In Vitro Techniques; Mammals; Methacholine Chloride; Motor Neurons; Nephropidae; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Parasympathetic; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Piperidines; Pirenzepine; Receptors, Muscarinic; Sheep; Tetraisopropylpyrophosphamide; Urinary Bladder | 1991 |
Biphasic dose-response curves to arecoline in rat atria-mediation by a single promiscuous receptor or two receptor subtypes?
Topics: Animals; Arecoline; Dose-Response Relationship, Drug; GTP-Binding Proteins; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Pertussis Toxin; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Virulence Factors, Bordetella | 1991 |
Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Male; Muscle Contraction; Piperidines; Pirenzepine; Potassium; Pyrilamine; Receptors, Muscarinic | 1990 |
Some differential effects of 4-diphenylacetoxy-N-(2-chloroethyl)-piperidine hydrochloride on guinea-pig atria and ileum.
Topics: Animals; Aziridines; Cyclization; Diphenylacetic Acids; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Parasympatholytics; Piperidines; Temperature | 1990 |
Predominant acetylcholine-induced vasoconstriction in isolated, perfused simian facial veins.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Blood Pressure; Diltiazem; Face; Female; In Vitro Techniques; Macaca; Male; Muscle, Smooth, Vascular; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Potassium Chloride; Quinazolines; Receptors, Muscarinic; Saponins; Vasoconstriction; Veins | 1990 |
Role of hypothalamic cholecystokinin octapeptide in the colonic motor response to a meal in rats.
Topics: Animals; Atropine; Benzodiazepinones; Cholecystokinin; Colon; Devazepide; Electromyography; Food; Gastrointestinal Motility; Hypothalamic Area, Lateral; Hypothalamus; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Receptors, Muscarinic; Sincalide; Ventromedial Hypothalamic Nucleus | 1991 |
Inhibition of the morphine withdrawal syndrome by a novel muscarinic antagonist (4-DAMP).
Topics: Animals; Hemodynamics; Morphine; Muscarinic Antagonists; Naloxone; Parasympatholytics; Piperidines; Pirenzepine; Rats; Substance Withdrawal Syndrome | 1991 |
Characterization of muscarinic receptors in dog tracheal smooth muscle cells.
Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea | 1991 |
Telenzepine inhibits electrically-stimulated, acetylcholine plus histamine-mediated acid secretion in the mouse isolated stomach by blockade of M1 muscarine receptors.
Topics: Acetylcholine; Alkaloids; Animals; Anti-Ulcer Agents; Electric Stimulation; Furans; Gastric Acid; Gastric Mucosa; Histamine; Mice; Muscarinic Antagonists; Naphthalenes; p-Methoxy-N-methylphenethylamine; Parasympatholytics; Piperidines; Pirenzepine; Stomach; Thiazepines; Vagus Nerve | 1991 |
Prejunctional muscarinic receptors on cholinergic nerves in guinea pig airways are of the M2 subtype.
Topics: Animals; Diamines; Electric Stimulation; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Male; Parasympathetic Nervous System; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1991 |
Native Xenopus oocytes express two types of muscarinic receptors.
Topics: Animals; Atropine; Elapid Venoms; Female; Oligonucleotide Probes; Oligonucleotides, Antisense; Oocytes; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Xenopus laevis | 1991 |
Natriuresis, kaliuresis and antidiuresis induced by central carbachol injection are mediated by muscarinic M1 receptors.
Topics: Animals; Carbachol; Diamines; Diuresis; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Muscarinic Antagonists; Natriuresis; Piperidines; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Activation of the pharmacologically defined M3 muscarinic receptor depolarizes hippocampal pyramidal cells.
Topics: Animals; Carbachol; Evoked Potentials; Hippocampus; In Vitro Techniques; Kinetics; Parasympatholytics; Piperidines; Pirenzepine; Pyramidal Tracts; Rats; Receptors, Muscarinic | 1990 |
Ventral medulla sites of muscarinic receptor subtypes involved in cardiorespiratory control.
Topics: Animals; Carbon Dioxide; Cardiovascular Physiological Phenomena; Cardiovascular System; Cats; Chemoreceptor Cells; Female; Male; Medulla Oblongata; Parasympatholytics; Phrenic Nerve; Piperidines; Pirenzepine; Receptors, Muscarinic; Respiratory Physiological Phenomena; Respiratory System | 1990 |
Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle.
Topics: Bronchi; Humans; In Vitro Techniques; Ipratropium; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Pharmacological evidence for distinct muscarinic receptor subtypes coupled to the inhibition of adenylate cyclase and to the increased generation of inositol phosphates in the guinea pig myometrium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myometrium; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Type C Phospholipases; Uterine Contraction | 1990 |
Muscarinic M3 receptors are coupled to two signal transduction pathways in rat submandibular cells.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Parasympatholytics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Signal Transduction; Submandibular Gland | 1990 |
Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle.
Topics: Animals; Cattle; In Vitro Techniques; Inositol Phosphates; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1990 |
Brain M3 muscarinic receptors are involved in the ACTH-induced reversal of hemorrhagic shock.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Brain Chemistry; Female; Heart Rate; Injections, Intraventricular; Male; Piperidines; Pirenzepine; Pulse; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Shock, Hemorrhagic | 1990 |
Muscarinic M1 receptors stimulate phosphoinositide hydrolysis in bovine cerebral arteries.
Topics: Animals; Cattle; Cerebral Arteries; Diamines; Endothelium, Vascular; Hydrolysis; Inositol Phosphates; Kinetics; Oxotremorine; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Signal Transduction | 1990 |
Labeling of rat heart muscarinic receptors using the new M2 selective antagonist [3H]AF-DX 384.
Topics: Affinity Labels; Animals; Atropine; Binding, Competitive; Male; Muscarinic Antagonists; Myocardium; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1990 |
The binding of [3H]4-diphenylacetoxy-N-methylpiperidine methiodide to longitudinal ileal smooth muscle muscarinic receptors.
Topics: Animals; Binding, Competitive; Diamines; Gallamine Triethiodide; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Muscarinic receptor subtypes mediating negative chrono- and inotropic responses in isolated, blood-perfused dog right atria.
Topics: Animals; Atropine; Carbachol; Cardiotonic Agents; Dogs; Electric Stimulation; Female; Heart Atria; Male; Myocardial Contraction; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vagus Nerve | 1990 |
Characterization of presynaptic vascular muscarinic receptors inhibiting endogenous noradrenaline overflow in the portal vein of the freely moving rat.
Topics: Animals; Catecholamines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Male; Muscle, Smooth, Vascular; Norepinephrine; Piperidines; Pirenzepine; Portal Vein; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synapses | 1990 |
Effects of chain-length and unsaturation on affinity and selectivity at muscarinic receptors.
Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Parasympathomimetics; Piperidines; Receptors, Muscarinic; Structure-Activity Relationship | 1990 |
Autoradiographic visualization of muscarinic receptor subtypes in human and guinea pig lung.
Topics: Animals; Autoradiography; Binding Sites; Diamines; Guinea Pigs; Humans; Lung; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Tritium | 1990 |
M1 and M2 muscarinic receptors mediate excitation and inhibition of guinea-pig intracardiac neurones in culture.
Topics: Action Potentials; Animals; Cells, Cultured; Ganglia; Guinea Pigs; Heart; Membrane Potentials; Muscarine; Neural Inhibition; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
[3H]N-methylscopolamine binding studies reveal M2 and M3 muscarinic receptor subtypes on cerebellar granule cells in primary culture.
Topics: Animals; Atropine; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebellum; Diamines; Granulocytes; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1990 |
Muscarinic receptor subtypes in canine trachea.
Topics: Acetylcholine; Animals; Dogs; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptors, Muscarinic; Regression Analysis; Trachea | 1990 |
An M3-like muscarinic autoreceptor regulates the in vivo release of acetylcholine in rat striatum.
Topics: Acetylcholine; Animals; Atropine; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dose-Response Relationship, Drug; Male; Neostigmine; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Time Factors | 1990 |
Muscarinic receptor subtypes on rat pancreatic acini: secretion and binding studies.
Topics: Acetylcholine; Amylases; Animals; Benzodiazepinones; Binding Sites; Male; N-Methylscopolamine; Pancreas; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1986 |
Muscarinic receptor reserve and beta-adrenergic sensitivity in tracheal smooth muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1989 |
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor.
Topics: Animals; Brain Stem; Corpus Striatum; Cyclic AMP; Diamines; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic | 1989 |
Inhibition of cyclic AMP formation in N1E-115 neuroblastoma cells is mediated by a non-cardiac M2 muscarinic receptor subtype.
Topics: Animals; Binding, Competitive; Cyclic AMP; Mice; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Piperidines; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured | 1989 |
Evidence of muscarinic receptor subtypes in airway smooth muscle of normal volunteers and of chronic obstructive pulmonary disease patients.
Topics: Atropine; Forced Expiratory Volume; Humans; Lung Diseases, Obstructive; Muscle, Smooth; Piperidines; Pirenzepine; Receptors, Muscarinic; Respiratory Muscles | 1989 |
Subtypes of muscarinic receptors in pancreatic exocrine secretion in anesthetized dog.
Topics: Animals; Atropine; Bethanechol Compounds; Dogs; Female; Kinetics; Male; Pancreas; Pancreatic Juice; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Reference Values | 1989 |
Effect of M2 muscarinic receptor antagonist 4-DAMP, on prostaglandin synthesis and mechanical function in the isolated rabbit heart.
Topics: Animals; Coronary Circulation; Drug Interactions; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Parasympatholytics; Parasympathomimetics; Piperidines; Prostaglandins; Rabbits; Receptors, Muscarinic | 1989 |
Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1.
Topics: Arecoline; Atropine; Carbachol; Cell Membrane; Humans; Neuroblastoma; Piperidines; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
The X-ray crystal structure of 4-diphenylcarbamyl-N-methyl-piperidine methobromide (the carbamate analogue of 4-DAMP methiodide).
Topics: Crystallization; Molecular Conformation; Piperidines; X-Ray Diffraction | 1989 |
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype.
Topics: Animals; Calcium; Gallamine Triethiodide; Ganglia, Spinal; Ganglia, Sympathetic; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Piperidines; Pirenzepine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Effect of selective muscarinic antagonists on peristaltic contractions in opossum smooth muscle.
Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Female; Male; Manometry; Muscle Contraction; Muscle, Smooth; Opossums; Peristalsis; Piperidines; Pirenzepine; Receptors, Muscarinic; Vagus Nerve | 1986 |
Development of the muscarinic receptor in rabbit gastric smooth muscle.
Topics: Animals; Animals, Newborn; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Kinetics; Muscle Contraction; Muscle Development; Muscle, Smooth; N-Methylscopolamine; Phenethylamines; Piperidines; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Stomach | 1988 |
Affinity of muscarinic receptor antagonists for three putative muscarinic receptor binding sites.
Topics: Animals; Buffers; Cerebral Cortex; In Vitro Techniques; Male; Myocardium; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland | 1989 |
Different antagonist binding properties of rat pancreatic and cardiac muscarinic receptors.
Topics: Animals; Binding, Competitive; GTP-Binding Proteins; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Type C Phospholipases | 1987 |
Displacement of [3H]oxotremorine-M binding by muscarinic antagonists in guinea-pig atrial and ileal membrane homogenates.
Topics: Animals; Atropine; Binding, Competitive; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Oxotremorine; Parasympatholytics; Piperidines | 1988 |
The affinity of some acetylenic analogues of 4-DAMP methobromide for muscarinic receptors in guinea-pig ileum and atria.
Topics: Animals; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Piperidines; Receptors, Muscarinic; Structure-Activity Relationship | 1988 |
The endogenous muscarinic acetylcholine receptor in Xenopus oocytes is of the M3 subtype.
Topics: Acetylcholine; Animals; Female; In Vitro Techniques; Membrane Potentials; Oocytes; Piperidines; Pirenzepine; Receptors, Cholinergic; Xenopus laevis | 1988 |
The role of M2 muscarinic receptors in the posterior hypothalamus in the pressor response to intracerebroventricularly-injected neostigmine.
Topics: Animals; Atropine; Blood Pressure; Heart Rate; Hypothalamus; Injections, Intraventricular; Male; Neostigmine; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Muscarinic receptor subtypes mediating vasodilation in the pulmonary artery.
Topics: Animals; Binding Sites; Cell Membrane; Diamines; Endothelium, Vascular; Lung; Male; Piperidines; Pirenzepine; Pulmonary Artery; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Vasodilation | 1988 |
Blockade of brain M2 muscarinic receptors lowers blood pressure in spontaneously hypertensive rats.
Topics: Animals; Atropine Derivatives; Blood Pressure; Brain; Male; Parasympatholytics; Parasympathomimetics; Physostigmine; Piperidines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1988 |
Binding of muscarine receptor antagonists to pig coronary smooth muscle.
Topics: Animals; Atropine; Carbachol; Coronary Vessels; Heart Atria; In Vitro Techniques; Muscle, Smooth, Vascular; Piperazines; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Swine; Tritium | 1988 |
Receptor binding profiles of some selective muscarinic antagonists.
Topics: Animals; Cerebral Cortex; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Myocardial Contraction; Parasympatholytics; Parotid Gland; Piperidines; Pirenzepine; Procyclidine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Urinary Bladder | 1988 |
Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.
Topics: Animals; Dicyclomine; Ganglia, Sympathetic; Hippocampus; Male; Myocardium; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Submandibular Gland | 1987 |
Identification of muscarinic M2 receptors on single muscle cells of the human and guinea pig intestine.
Topics: Acetylcholine; Animals; Atropine; Guinea Pigs; Humans; Jejunum; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptors, Muscarinic | 1987 |
Changes in regional myocardial perfusion by muscarinic receptor subtypes in dogs.
Topics: Acetylcholine; Animals; Coronary Circulation; Dogs; Endocardium; Female; Male; Myocardium; Perfusion; Pericardium; Piperidines; Pirenzepine; Receptors, Muscarinic | 1986 |
A further search for selective antagonists at M2-muscarinic receptors.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Muscle, Smooth; Myocardial Contraction; Myocardium; Parasympathomimetics; Piperidines; Receptors, Muscarinic | 1986 |
Muscarinic receptors mediating suppression of the M-current in guinea-pig olfactory cortex neurones may be of the M2-subtype.
Topics: Animals; Cerebral Cortex; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscarine; Piperidines; Receptors, Muscarinic | 1987 |
Determination of the muscarinic receptor subtype mediating vasodilatation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atropine; Benzodiazepinones; Carbachol; Dogs; Female; Femoral Artery; Gallamine Triethiodide; In Vitro Techniques; Male; Pancuronium; Parasympatholytics; Phenethylamines; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vasodilation | 1985 |
A search for selective antagonists at M2 muscarinic receptors.
Topics: Animals; Atrial Function; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Rate; Ileum; Muscle Contraction; Myocardial Contraction; Piperidines; Receptors, Muscarinic; Structure-Activity Relationship | 1985 |
Pharmacologic identification, activation and antagonism of two muscarine receptor subtypes in the lower esophageal sphincter.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagogastric Junction; Hexamethonium Compounds; Opossums; Piperidines; Pirenzepine; Receptors, Muscarinic; Tetrodotoxin; Vagus Nerve | 1984 |
Pressor response induced by the hippocampal administration of neostigmine is suppressed by M1 muscarinic antagonist.
Topics: Animals; Atropine Derivatives; Blood Pressure; Drug Interactions; Gallamine Triethiodide; Heart Rate; Hippocampus; Male; Muscarinic Antagonists; Neostigmine; Parasympathomimetics; Piperidines; Pirenzepine; Pressoreceptors; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Ligand-binding properties of an unusual nicotinic acetylcholine receptor subtype on isolated outer hair cells from guinea pig cochlea.
Topics: Animals; Atropine; Binding, Competitive; Bungarotoxins; Cochlea; Female; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Ligands; Male; Muscarinic Antagonists; Nicotine; Parasympatholytics; Piperidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Nicotinic; Strychnine | 1995 |
Muscarinic receptor subtypes mediating vasodilation and vasoconstriction in isolated, perfused simian coronary arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Macaca; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth, Vascular; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasoconstriction; Vasodilation | 1993 |
A single transmitter regulates gene expression through two separate mechanisms: cholinergic regulation of phenylethanolamine N-methyltransferase mRNA via nicotinic and muscarinic pathways.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Medulla; Animals; Atropine; Binding, Competitive; Calcimycin; Calcium; Carbachol; Cattle; Cells, Cultured; Colforsin; Epinephrine; Gene Expression Regulation, Enzymologic; Hexamethonium; Hexamethonium Compounds; Kinetics; Muscarine; Nicotine; Phenylethanolamine N-Methyltransferase; Piperidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; RNA, Messenger | 1994 |
Muscarinic acetylcholine receptors on an identified motor neurone in the cockroach, Periplaneta americana.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Atropine; Dose-Response Relationship, Drug; Evoked Potentials; Ganglia, Invertebrate; In Vitro Techniques; Male; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Periplaneta; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Vertebrates | 1994 |
Cholinergic and VIP-ergic pathways mediate histamine H2 receptor-induced cyclical secretion in the guinea pig colon.
Topics: Acetylcholine; Amiloride; Animals; Atropine; Choline; Colon; Dimaprit; Electric Conductivity; Guinea Pigs; Histamine Release; Intestinal Mucosa; Male; ortho-Aminobenzoates; Piperidines; Pirenzepine; Receptors, Histamine H2; Vasoactive Intestinal Peptide | 1995 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Cholinergic activation of Cl- secretion in rat colonic epithelia.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Binding, Competitive; Chlorides; Cholinergic Agonists; Cholinergic Antagonists; Colon; Dose-Response Relationship, Drug; Epithelium; Hexamethonium; In Vitro Techniques; Ion Transport; Male; Muscarinic Agonists; Parasympatholytics; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Wistar | 1995 |
The role of acetylcholine in regulating secretory responsiveness in rat sweat glands.
Topics: Acetylcholine; Age Factors; Animals; Atropine; Parasympatholytics; Pilocarpine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sweat Glands; Time Factors | 1995 |
Muscarinic cholinergic receptor subtypes in human detrusor muscle studied by labeled and nonlabeled pirenzepine, AFDX-116 and 4DAMP.
Topics: Aged; Cystectomy; Female; Humans; Male; Muscle, Smooth; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Urinary Bladder Neoplasms | 1995 |
Synthesis, muscarinic blocking activity and molecular modeling studies of 4-DAMP-related compounds.
Topics: Animals; Crystallography, X-Ray; Guinea Pigs; Ileum; Models, Molecular; Molecular Conformation; Molecular Structure; Muscarinic Antagonists; Myocardium; Piperidines; Receptors, Muscarinic | 1995 |
Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Carbachol; Cell Line; Codon; GTP-Binding Proteins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Parasympatholytics; Piperidines; Proline; Protein Conformation; Rats; Receptors, Muscarinic; Recombinant Proteins; Restriction Mapping; RNA; Scopolamine Derivatives; Transfection; Tryptophan | 1993 |
Muscarinic depression of synaptic transmission and blockade of norepinephrine-induced long-lasting potentiation in the dentate gyrus.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Cyclic AMP; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Muscarine; Norepinephrine; Parasympatholytics; Pertussis Toxin; Piperidines; Pirenzepine; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synapses; Synaptic Transmission; Virulence Factors, Bordetella | 1993 |
Release of endogenous acetylcholine from a vascularly perfused rat stomach in vitro; inhibition by M3 muscarinic autoreceptors and alpha-2 adrenoceptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Calcium; Clonidine; Diamines; Drug Interactions; Electric Stimulation; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Male; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Perfusion; Phenylephrine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Tetrodotoxin; Vagus Nerve | 1993 |
Neuroregulation of a chemosensitive afferent system in the canine distal esophagus.
Topics: Afferent Pathways; Animals; Atropine; Blood Pressure; Capsaicin; Chemoreceptor Cells; Dogs; Esophagus; Hexamethonium; Hexamethonium Compounds; Mucous Membrane; Nociceptors; Piperidines; Pressure; Pulse; Respiration; Substance P; Tetrodotoxin; Vagotomy | 1993 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Formation of inositol phosphates mediated by M3 muscarinic receptors in type-1 and type-2 astrocytes from neonatal rat cerebral cortex.
Topics: Animals; Animals, Newborn; Astrocytes; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Tubocurarine | 1994 |
Regulation of pancreatic polypeptide release is mediated through M3 muscarinic receptors.
Topics: Animals; Atropine; Cholecystokinin; Dogs; Female; Gastric Acid; Male; Pancreatic Juice; Pancreatic Polypeptide; Parasympatholytics; Piperidines; Pirenzepine; Proglumide; Receptors, Muscarinic; Vagus Nerve | 1994 |
Hypotensive effect of an M2-selective muscarinic antagonist in anaesthetized guinea-pigs.
Topics: Animals; Atropine; Blood Pressure; Depression, Chemical; Diamines; Guinea Pigs; Heart Rate; Male; Muscarinic Antagonists; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
A novel cholinergic "slow effect" of efferent stimulation on cochlear potentials in the guinea pig.
Topics: Acoustic Stimulation; Animals; Atropine; Bicuculline; Cochlea; Decamethonium Compounds; Dose-Response Relationship, Drug; Efferent Pathways; Electric Stimulation; Guinea Pigs; Hair Cells, Auditory, Outer; Hexamethonium; Membrane Potentials; Models, Neurological; Nerve Fibers; Piperidines; Strychnine; Time Factors; Vestibulocochlear Nerve | 1995 |
Pressor effects of acetylcholine injected into the lateral septal area of conscious rats.
Topics: Acetylcholine; Adrenal Glands; Animals; Atropine; Blood Pressure; Ganglionic Blockers; Injections, Intraventricular; Male; Parasympatholytics; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar; Septal Nuclei; Stimulation, Chemical; Vasopressins | 1994 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP-Binding Proteins; In Vitro Techniques; Iris; Male; Microinjections; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Virulence Factors, Bordetella | 1995 |
Regional differences in motor responsiveness to antimuscarinic drugs in rabbit isolated small and large intestine.
Topics: Animals; Atropine; Benzodiazepinones; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Intestine, Large; Intestine, Small; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1995 |
Localization of M3 muscarinic receptor subtype and mRNA in the human eye.
Topics: Acetylcholine; Adult; Aged; Anterior Eye Segment; Autoradiography; Blotting, Northern; Ciliary Body; Female; Humans; In Situ Hybridization; Iris; Male; Middle Aged; Parasympatholytics; Piperidines; Receptors, Muscarinic; RNA, Messenger | 1994 |
Methoctramine induces nonspecific airway hyperresponsiveness in vivo.
Topics: Aerosols; Albuterol; Animals; Arachidonic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Diamines; Drug Synergism; Gallamine Triethiodide; Guinea Pigs; Histamine; Male; Muscarinic Antagonists; Ovalbumin; Parasympatholytics; Piperazines; Piperidines; Platelet Activating Factor; Propranolol; Receptors, Muscarinic | 1994 |
Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Aporphines; Binding, Competitive; Carbachol; Cells, Cultured; Cyclic AMP; Diamines; Dogs; Female; Hydrolysis; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphatidylinositols; Piperidines; Plants, Medicinal; Receptors, Muscarinic; Trachea | 1994 |
Muscarinic M3 receptor-mediated release of gastrin from canine antral G cells in primary culture.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Enterochromaffin Cells; Gastrins; Muscarinic Antagonists; Parasympathetic Nervous System; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Receptor, Muscarinic M3; Receptors, Muscarinic; Stimulation, Chemical | 1995 |
Opposite modulation by muscarinic M1 and M3 receptors of acetylcholine release from guinea pig ileum as measured directly.
Topics: Acetylcholine; Analysis of Variance; Animals; Bethanechol; Bethanechol Compounds; Chromatography, High Pressure Liquid; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Piperidines; Quinuclidines; Receptors, Muscarinic; Thiophenes | 1993 |
Vitamin D status modulates rat colonic M3 muscarinic receptor characteristics and coupling to guanylate cyclase.
Topics: Animals; Atropine; Colon; Diamines; Enzyme Activation; Guanylate Cyclase; Male; Muscarinic Antagonists; Nutritional Status; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vitamin D | 1994 |
Receptor mediated presynaptic modulation of the release of noradrenaline in human papillary muscle.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atropine; Berberine; Chromatography, High Pressure Liquid; Culture Techniques; Dopamine beta-Hydroxylase; Electric Stimulation; Feedback; Female; Heart Atria; Humans; Immunohistochemistry; Male; Middle Aged; Norepinephrine; Oxotremorine; Pancuronium; Papillary Muscles; Piperidines; Presynaptic Terminals; Receptors, Muscarinic; Sympathetic Nervous System; Tritium; Xylazine | 1994 |
Inhibition of aceclidine-stimulated outflow facility, accommodation and miosis in rhesus monkeys by muscarinic receptor subtype antagonists.
Topics: Accommodation, Ocular; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pupil; Quinuclidines | 1994 |
Facilitatory but nonessential role of the muscarinic cholinergic system in the generation of long-term potentiation of population spikes in the dentate gyrus in vivo.
Topics: Animals; Evoked Potentials; Hippocampus; Injections, Intraventricular; Long-Term Potentiation; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine | 1994 |
Muscarinic M3 receptors mediate contractions in rabbit, endothelium-denuded aorta in vitro.
Topics: Animals; Aorta, Thoracic; Dioxolanes; Endothelium, Vascular; Female; In Vitro Techniques; Piperidines; Rabbits; Receptors, Muscarinic; Vasoconstriction | 1994 |
Effects of slaframine and 4-diphenylacetoxy-N-methylpiperidine methiodide (4DAMP) on pancreatic exocrine secretion in the bovine.
Topics: Alkaloids; alpha-Amylases; Animals; Cattle; Chymotrypsin; Hydrogen-Ion Concentration; Male; Muscarinic Antagonists; Pancreas; Pancreatic Juice; Parasympatholytics; Parasympathomimetics; Piperidines; Proteins | 1994 |
In vivo study of the role of muscarinic receptors in the parasympathetic control of rabbit colonic motility.
Topics: Action Potentials; Animals; Colon; Diamines; Electric Stimulation; Gallamine Triethiodide; Gastrointestinal Motility; Male; Muscle, Smooth; Parasympathetic Nervous System; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vagus Nerve | 1994 |
Assessment of the muscarinic receptor subtypes involved in pilocarpine-induced seizures in mice.
Topics: Animals; Atropine; Cerebral Ventricles; Injections, Intraventricular; Male; Mice; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Seizures | 1994 |
Cholinergic dilatation and constriction of feline cerebral blood vessels are mediated by stimulation of phosphoinositide metabolism via two different muscarinic receptor subtypes.
Topics: Animals; Carbachol; Cats; Cerebral Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Muscle, Smooth, Vascular; Parasympatholytics; Phosphatidylinositols; Pia Mater; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasoconstriction; Vasodilation | 1994 |
In vitro pharmacologic characterization of a cholinergic receptor on outer hair cells.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Bungarotoxins; Carbachol; Choline; Cholinergic Antagonists; Curare; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Nicotine; Piperidines; Pirenzepine; Quinolizines; Receptors, Cholinergic; Strychnine; Trimethaphan | 1994 |
Diabetes-induced alterations in the properties of muscarinic cholinergic receptors in rat vas deferens.
Topics: Animals; Atropine; Binding, Competitive; Diabetes Mellitus, Experimental; Diamines; Insulin; Male; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Up-Regulation; Vas Deferens | 1994 |
Insertion mutagenesis as a tool to predict the secondary structure of a muscarinic receptor domain determining specificity of G-protein coupling.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; Carbachol; Cell Line; Chlorocebus aethiops; GTP-Binding Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Insertional; N-Methylscopolamine; Phosphatidylinositols; Piperidines; Protein Structure, Secondary; Rats; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Transfection | 1994 |
Involvement of muscarinic acetylcholine receptors in regulation of kitten visual cortex plasticity.
Topics: Animals; Autoradiography; Cats; Geniculate Bodies; Ligands; Neuronal Plasticity; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Tetrodotoxin; Visual Cortex | 1994 |
Neurogenic inhibition of duodenal and jejunal motility in the anaesthetized rat.
Topics: Animals; Arginine; Duodenum; Gastrointestinal Motility; Jejunum; Male; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Sympatholytics; Vagotomy | 1994 |
Nicotinic and muscarinic synaptic transmission in canine intracardiac ganglion cells innervating the sinoatrial node.
Topics: Acetylcholine; Animals; Bethanechol Compounds; Dogs; Electric Stimulation; Evoked Potentials; Female; Ganglia, Autonomic; Heart; Hexamethonium Compounds; Male; Membrane Potentials; Neurons; Neurotransmitter Agents; Parasympatholytics; Piperidines; Receptors, Muscarinic; Receptors, Nicotinic; Sinoatrial Node; Synapses; Synaptic Transmission | 1993 |
Evidence of muscarinic acetylcholine receptors and GTP-binding proteins in peritoneal mesothelial cells in vitro.
Topics: Animals; Atropine; Binding, Competitive; Cells, Cultured; Epithelium; GTP-Binding Proteins; Humans; Peritoneum; Piperidines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic | 1993 |
Characterization of the muscarinic receptors in the mesenteric vascular bed of spontaneously hypertensive rats.
Topics: Animals; Atropine; Benzodiazepinones; Endothelium, Vascular; Hypertension; Male; Mesenteric Artery, Superior; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Muscarinic; Vasodilation | 1993 |
Pharmacological characterization of muscarinic cholinergic receptors in cat pons and cortex. Preliminary study.
Topics: Animals; Atropine; Binding, Competitive; Cats; Cerebral Cortex; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pons; Receptors, Muscarinic | 1994 |
Role of spinal and supraspinal muscarinic receptors in the expression of morphine withdrawal symptoms in the rat.
Topics: Animals; Blood Pressure; Cerebral Ventricles; Heart Rate; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Muscarinic Antagonists; Naloxone; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Spinal Cord; Substance Withdrawal Syndrome; Time Factors | 1993 |
Reversibility of diabetes- and diuresis-induced alterations in rat bladder dome muscarinic receptors.
Topics: Animals; Binding, Competitive; Body Weight; Cell Membrane; Diabetes Mellitus, Experimental; Diamines; Diuresis; Drinking Behavior; Insulin; Kinetics; Male; Myocardium; Organ Size; Parasympatholytics; Piperidines; Pirenzepine; Prostate; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sucrose; Testosterone; Up-Regulation; Urinary Bladder | 1994 |
Pharmacological characterization of muscarinic receptors in neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cyclic AMP; Inositol Phosphates; Kinetics; Muscarine; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1993 |
Agonist-induced down-regulation and antagonist-induced up-regulation of m2- and m3-muscarinic acetylcholine receptor mRNA and protein in cultured cerebellar granule cells.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Down-Regulation; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; RNA, Messenger; Up-Regulation | 1993 |
Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum.
Topics: Animals; Arterioles; Capsaicin; Guinea Pigs; Ileum; Intestinal Mucosa; Parasympatholytics; Perfusion; Piperidines; Tetrodotoxin; Vasodilation; Vasodilator Agents | 1993 |
Muscarinic receptors in isolated guinea pig pancreatic ducts.
Topics: Amidohydrolases; Animals; Binding, Competitive; Guinea Pigs; In Vitro Techniques; Male; Molecular Weight; N-Methylscopolamine; Pancreatic Ducts; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Piperidines; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1993 |
Heterogeneity of guinea-pig lung muscarinic receptors revealed by [3H]4-DAMP-binding.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Kinetics; Lung; Male; Myocardium; Piperidines; Rabbits; Radioligand Assay; Receptors, Muscarinic; Tritium | 1993 |
Age-related changes in pulmonary muscarinic receptor binding properties.
Topics: Aging; Animals; Binding, Competitive; Guinea Pigs; Lung; Male; Muscarine; Parasympathomimetics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1993 |
Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors.
Topics: Acetylcholine; Animals; Carbachol; Cell Line; GTP-Binding Proteins; Kinetics; Models, Structural; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Piperidines; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Recombinant Fusion Proteins; Scopolamine Derivatives; Signal Transduction; Transfection; Yohimbine | 1993 |
Characterization of muscarinic receptors in cultured human iris sphincter and ciliary smooth muscle cells.
Topics: Binding, Competitive; Cells, Cultured; Ciliary Body; Humans; Iris; Muscle, Smooth; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1993 |
Autoradiographic mapping of M3 muscarinic receptors in the rat brain.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tritium | 1993 |
Cholinergic M2 muscarinic receptor-mediated inhibition of endogenous noradrenaline release from the isolated vascularly perfused rat stomach.
Topics: Animals; Arteries; Atrial Function; Atropine; Depression, Chemical; Diamines; Electric Stimulation; Ethylmaleimide; Heart Atria; Male; Myocardial Contraction; Nerve Endings; Norepinephrine; Oxotremorine; Parasympatholytics; Perfusion; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Vagus Nerve; Virulence Factors, Bordetella | 1993 |
Differential effects of antimuscarinic agents on intestinal motility in the conscious dog.
Topics: Animals; Atropine; Dogs; Female; Gastrointestinal Motility; Heart Rate; Male; Parasympatholytics; Piperidines; Pirenzepine; Pupil; Receptors, Muscarinic | 1993 |
Regional binding of 4-diphenylacetoxy-N-methylpiperidine methobromide (4-DAMP) to muscarinic receptors in rat brain and comparative analysis of minimum energy conformations.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Image Processing, Computer-Assisted; In Vitro Techniques; Molecular Conformation; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Tissue Distribution | 1993 |
Muscarinic receptor regulation and 2nd messenger responses in rat neocortex cultures.
Topics: Animals; Binding, Competitive; Carbachol; Cells, Cultured; Cerebral Cortex; Down-Regulation; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Muscarinic receptors in the aortae of normo- and hypertensive rats: a binding study.
Topics: Acetylcholine; Animals; Aorta; Atropine; Binding, Competitive; Endothelium, Vascular; Guanylyl Imidodiphosphate; Hypertension; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Muscarinic; Scopolamine; Tropanes | 1993 |
Subtype of muscarinic receptors mediating relaxation and contraction in the rat iris dilator smooth muscle.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Functional characterization of muscarinic receptors in murine airways.
Topics: Administration, Inhalation; Airway Resistance; Animals; Atropine; Bronchi; Electric Stimulation; In Vitro Techniques; Isometric Contraction; Lung Compliance; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Trachea | 1993 |
Muscarinic depression of excitatory synaptic transmission mediated by the presynaptic M3 receptors in the rat neostriatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Depression, Chemical; Electric Stimulation; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Presynaptic; Synaptic Transmission | 1995 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |
Endocrine and metabolic response to muscarinic stimulation and inhibition in the ruminant: effects of slaframine.
Topics: Alkaloids; Animals; Blood Glucose; Endocrine Glands; Fatty Acids, Nonesterified; Female; Goat Diseases; Goats; Growth Hormone; Hyperglycemia; Hyperinsulinism; Injections, Intravenous; Insulin; Male; Muscarinic Agonists; Muscarinic Antagonists; Parasympathomimetics; Piperidines; Receptors, Muscarinic; Thyroxine; Triiodothyronine | 1995 |
Muscarinic receptor subtypes mediating catecholamine secretion and increase in intracellular Ca2+ concentration in adrenal chromaffin cells of the guinea pig.
Topics: Adrenal Medulla; Animals; Calcium; Cells, Cultured; Cholinergic Agents; Chromatography, High Pressure Liquid; Diamines; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Kinetics; Male; Methacholine Chloride; Muscarine; Norepinephrine; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
Antagonists have a greater selectivity for muscarinic receptor subtypes in intact cerebellar granule cells than in membranes.
Topics: Animals; Binding, Competitive; Cell Membrane; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Muscarinic Antagonists; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Time Factors | 1996 |
Mediation of the depolarization-induced [Ca(2+)]i increase in rat sublingual acini by acetylcholine released from nerve terminals.
Topics: Acetylcholine; Animals; Atropine; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cytosol; Fluorescent Dyes; Fura-2; Gallic Acid; Inositol 1,4,5-Trisphosphate; Male; Muscarinic Antagonists; Nerve Endings; Nicotinic Antagonists; Piperidines; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptors, Nicotinic; Sublingual Gland | 1996 |
On muscarinic control of neurogenic mucus secretion in ferret trachea.
Topics: Animals; Diamines; Electric Stimulation; Ferrets; In Vitro Techniques; Male; Mucus; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Sulfates; Sulfur Radioisotopes; Trachea; Tritium | 1996 |
Carbachol stimulates inositol phosphate formation in rat thalamus slices through muscarinic M3-receptor activation.
Topics: Animals; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Inositol Phosphates; Male; Muscarinic Agonists; Muscarinic Antagonists; Organ Culture Techniques; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Thalamus; Tritium | 1996 |
Muscarinic antagonists microinjected into the subthalamic nucleus decrease muscular rigidity in reserpinized rats.
Topics: Anesthetics, Intravenous; Animals; Chloral Hydrate; Cholinergic Antagonists; Electromyography; Locomotion; Male; Microinjections; Muscarinic Antagonists; Muscle Rigidity; Muscle, Skeletal; Piperidines; Pirenzepine; Rats; Rats, Wistar; Reserpine; Sympatholytics; Thalamic Nuclei | 1996 |
Possible involvement of muscarinic M1 and M3 receptor subtypes mediating vasodilation in isolated, perfused canine lingual arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Analysis of Variance; Animals; Dogs; Dose-Response Relationship, Drug; Female; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Piperidines; Pirenzepine; Receptors, Muscarinic; Saponins; Tongue; Vasoconstriction; Vasodilation | 1996 |
Pharmacological characterization of the muscarinic receptors mediating contraction of canine saphenous vein.
Topics: Animals; Dioxolanes; Dogs; Female; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Oxotremorine; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptors, Muscarinic; Saphenous Vein | 1995 |
Muscarinic receptor subtypes in the submandibular gland and the urinary bladder of the rabbit: in vivo and in vitro functional comparisons of receptor antagonists.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antagonists; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Submandibular Gland; Urinary Bladder | 1995 |
The roles of muscarinic receptor subtypes in modulation of nasal ciliary action.
Topics: Atropine; Cilia; Gallamine Triethiodide; Humans; In Vitro Techniques; Methacholine Chloride; Mucociliary Clearance; Muscarinic Agonists; Muscarinic Antagonists; Nasal Mucosa; Piperidines; Pirenzepine; Receptors, Muscarinic | 1996 |
Acetylcholine stimulates growth hormone secretion in the neonatal rat pituitary.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Animals, Newborn; Atropine; Diamines; Dose-Response Relationship, Drug; Female; Growth Hormone; Male; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar | 1996 |
Pharmacological characteristics of indoline derivatives in muscarinic receptor subtypes.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Indoles; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Myocardial Contraction; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vas Deferens | 1996 |
M2 muscarinic receptor inhibition of agonist-induced cyclic adenosine monophosphate accumulation and relaxation in the guinea pig ileum.
Topics: Animals; Cyclic AMP; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscle Relaxation; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic | 1997 |
Both M1 and M3 receptors regulate exocrine secretion by mucous acini.
Topics: Animals; Male; Mucus; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Sublingual Gland | 1996 |
Effect of cholinergic agonists on gastrin release from primary cultures of human antral G cells.
Topics: Adult; Antibodies; Bombesin; Calcium; Carbachol; Cells, Cultured; Female; Gastrins; Humans; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pyloric Antrum; Somatostatin | 1997 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 1996 |
Critical role for M3 muscarinic receptors in paradoxical sleep generation in the cat.
Topics: Animals; Carbachol; Cats; Muscarinic Antagonists; Piperidines; Receptors, Muscarinic; Sleep | 1997 |
Muscarinic acetylcholine receptors on rat thymocytes: their possible involvement in DNA fragmentation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Atropine; Binding, Competitive; Carbachol; DNA Fragmentation; Electrophoresis, Agar Gel; Hydrocortisone; Injections, Subcutaneous; Isotope Labeling; Male; Muscarinic Agonists; Muscarinic Antagonists; Nucleosomes; Oxotremorine; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Thymus Gland | 1997 |
Inhibition of M3 muscarinic acetylcholine receptor-mediated Ca2+ influx and intracellular Ca2+ mobilization in neuroblastoma cells by the Ca2+/calmodulin-dependent protein kinase inhibitor 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-trosyl]-4-phenylpipe
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Enzyme Inhibitors; Humans; Neuroblastoma; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Tumor Cells, Cultured | 1997 |
Pharmacological characterization of the muscarinic receptor subtypes responsible for the contractile response in the rat urinary bladder.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Analysis of Variance; Animals; Bethanechol; Diamines; Dose-Response Relationship, Drug; Female; Gallamine Triethiodide; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Structure-Activity Relationship; Urinary Bladder | 1997 |
Muscarinic control of phase III contractions and motilin release in dogs.
Topics: Animals; Cell Separation; Dogs; Duodenum; Female; Infusions, Intravenous; Intestinal Mucosa; Male; Motilin; Muscarinic Antagonists; Piperidines; Pirenzepine; Stomach | 1997 |
Functional characterization of peripheral muscarinic subtypes in anesthetized cats.
Topics: Animals; Atropine; Blood Pressure; Cats; Gallamine Triethiodide; Galvanic Skin Response; Heart Rate; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Superior Cervical Ganglion; Synaptic Transmission; Vagus Nerve; Vasodilation | 1997 |
Rodent biodistribution and metabolism of tritiated 4-DAMP, a M3 subtype-selective cholinoceptor ligand.
Topics: Animals; Male; Muscarinic Antagonists; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Tissue Distribution; Tritium | 1994 |
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
The muscarinic modulation of [3H]D-aspartate efflux and [Ca2+]i levels in rat cerebellar granule cells.
Topics: Acetylcholine; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Electric Stimulation; Muscarinic Antagonists; Neurons; Piperidines; Potassium Chloride; Rats; Receptors, Muscarinic | 1997 |
Carbachol-induced inositol phosphate formation in rat striatum is mediated by both M1 and M3 muscarinic receptors.
Topics: Animals; Carbachol; Corpus Striatum; Drug Evaluation, Preclinical; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar | 1997 |
Muscarinic receptor subtypes controlling the cationic current in guinea-pig ileal smooth muscle.
Topics: Animals; Carbachol; Dioxoles; Dose-Response Relationship, Drug; Electric Conductivity; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Patch-Clamp Techniques; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Contractile roles of the M2 and M3 muscarinic receptors in the guinea pig colon.
Topics: Animals; Colforsin; Colon; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Oxotremorine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Virulence Factors, Bordetella | 1998 |
Insulin secretion by gastrin-releasing peptide in mice: ganglionic versus direct islet effect.
Topics: Animals; Blood Glucose; Capsaicin; Cells, Cultured; Female; Ganglia, Sympathetic; Gastrin-Releasing Peptide; Glucagon; Hexamethonium; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Pancreas; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic | 1998 |
Two opposite signal transducing mechanisms regulate a G-protein-coupled guanylyl cyclase.
Topics: Animals; Carbachol; Cattle; Cell Membrane; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanylate Cyclase; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Trachea; Virulence Factors, Bordetella | 1998 |
(S)-Albuterol increases intracellular free calcium by muscarinic receptor activation and a phospholipase C-dependent mechanism in airway smooth muscle.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Calcium; Cattle; Estrenes; Piperidines; Propanolamines; Pyrrolidinones; Receptors, Muscarinic; Stereoisomerism; Trachea; Type C Phospholipases | 1998 |
Synthesis, antimuscarinic activity and quantitative structure-activity relationship (QSAR) of tropinyl and piperidinyl esters.
Topics: Animals; Esters; In Vitro Techniques; Kinetics; Male; Models, Molecular; Muscarinic Antagonists; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Tropanes | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Urinary Bladder | 1998 |
M2 and M3 muscarinic receptors couple, respectively, with activation of nonselective cationic channels and potassium channels in intestinal smooth muscle cells.
Topics: Animals; Atropine; Calcium; Carbachol; Guinea Pigs; Male; Muscarinic Agonists; Muscle, Smooth; Piperidines; Pirenzepine; Potassium Channels; Receptors, Muscarinic | 1998 |
Pharmacological and molecular characterization of muscarinic receptors in cat esophageal smooth muscle.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cats; Dioxoles; Electric Stimulation; Esophagus; Female; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Piperidines; Polymerase Chain Reaction; Receptors, Muscarinic; RNA, Messenger | 1998 |
Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Behavior, Animal; Carbachol; Cataplexy; Cholinergic Fibers; Dogs; Feeding Behavior; Female; GABA Agonists; Gallamine Triethiodide; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Muscimol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Piperidines; Pirenzepine; Prosencephalon | 1998 |
Muscarinic inhibition of substance P induced ion secretion in piglet jejunum.
Topics: Animals; Atropine; Carbachol; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Gallamine Triethiodide; Histamine; Ion Transport; Jejunum; Mecamylamine; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Substance P; Swine; Time Factors | 1998 |
Pharmacological profile of CEB-1957 and atropine toward brain muscarinic receptors and comparative study of their efficacy against sarin poisoning.
Topics: Animals; Atropine; Autoradiography; Binding, Competitive; Brain; Cholinesterase Inhibitors; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Poisoning; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Sarin; Thiophenes | 1998 |
Pharmacological and functional characterization of muscarinic receptors in the frog pars intermedia.
Topics: Acetylcholine; alpha-MSH; Animals; Calcium; Carbachol; Cyclic AMP; Enzyme Inhibitors; Inositol Phosphates; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Pertussis Toxin; Piperidines; Pituitary Gland; Protein-Tyrosine Kinases; Rana ridibunda; Receptors, Muscarinic; Signal Transduction; Virulence Factors, Bordetella | 1998 |
Calcium signaling in cultured human and rat duodenal enterocytes.
Topics: Animals; Calcium; Carbachol; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Duodenum; Extracellular Matrix; Fluorescent Dyes; Fura-2; Humans; Intestinal Mucosa; Male; Parasympatholytics; Piperidines; Rats; Rats, Inbred Lew; Signal Transduction; Sincalide; Vacuoles | 1998 |
Acetylcholine-induced calcium signaling along the rat colonic crypt axis.
Topics: Acetylcholine; Animals; Biological Transport; Calcium; Colon; Dose-Response Relationship, Drug; Heptanol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Signal Transduction; Tissue Distribution | 1998 |
Effects of chronic exercise on muscarinic receptor-mediated vasodilation in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Gallamine Triethiodide; Heart Rate; Male; Muscarinic Antagonists; Nicotinic Antagonists; Nitric Oxide; Physical Conditioning, Animal; Physical Exertion; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Tritium; Up-Regulation; Vasodilation; Vasodilator Agents | 1998 |
Acute exercise enhances receptor-mediated endothelium-dependent vasodilation by receptor upregulation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Clonidine; Endothelium, Vascular; In Vitro Techniques; Male; Muscarinic Antagonists; Physical Conditioning, Animal; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Thoracic Arteries; Tritium; Up-Regulation; Vasodilation | 1999 |
Prejunctional muscarinic receptors modulating acetylcholine release in rabbit detrusor smooth muscles.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Culture Techniques; Diamines; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Reference Values | 1998 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodide; Edrophonium; Glucose; Inositol; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neostigmine; Neuromuscular Blocking Agents; Nicotinic Agonists; Organ Preservation Solutions; Phosphatidylinositols; Piperidines; Pyridostigmine Bromide; Radiopharmaceuticals; Rats; Rats, Wistar; Tetrodotoxin; Trachea; Tritium; Tromethamine | 1998 |
M2 receptors in genito-urinary smooth muscle pathology.
Topics: Animals; Binding Sites; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Hypertrophy; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Organ Size; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Spinal Cord Injuries; Urinary Bladder; Urinary Bladder, Neurogenic | 1999 |
Pharmacologic study of muscarinic receptor subtypes and arteriolar dilations: a comparison of conducted and local responses.
Topics: Animals; Arterioles; Cheek; Cricetinae; Dose-Response Relationship, Drug; Microcirculation; Mouth Mucosa; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Reference Values; Scopolamine; Vasodilation | 1999 |
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1999 |
Function of M3 muscarinic receptors in the rat urinary bladder following partial outlet obstruction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder Neck Obstruction | 1999 |
Choline modulates cardiac membrane repolarization by activating an M3 muscarinic receptor and its coupled K+ channel.
Topics: Animals; Choline; Dogs; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Myocardium; Patch-Clamp Techniques; Piperidines; Potassium Channels; Receptor, Muscarinic M3; Receptors, Muscarinic | 1999 |
Effect of continuous administration of a cholinergic agonist on [3H]4-DAMP binding and m3 mRNA expression in cultured human ciliary muscle cells.
Topics: Carbachol; Cells, Cultured; Cholinergic Agonists; Ciliary Body; Humans; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic; RNA, Messenger | 1999 |
Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions.
Topics: Acetylcholine; Animals; Atropine; Diamines; Electric Stimulation; Gallbladder; Guinea Pigs; Hexamethonium; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Tetrodotoxin; Tropicamide | 1999 |
Selective alkylation of rat urinary bladder muscarinic receptors with 4-DAMP mustard reveals a contractile function for the M2 muscarinic receptor.
Topics: Alkylation; Animals; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; Receptors, Muscarinic; Signal Transduction; Urinary Bladder | 1999 |
M3 muscarinic receptor activation of a delayed rectifier potassium current in canine atrial myocytes.
Topics: Animals; Dogs; Heart; Membrane Potentials; Piperidines; Potassium Channels; Receptor, Muscarinic M3; Receptors, Muscarinic; Tetraethylammonium Compounds | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current.
Topics: Action Potentials; Animals; Atrial Function; Binding, Competitive; Dogs; Electrophysiology; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; Male; Membrane Potentials; Microelectrodes; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Parasympatholytics; Pilocarpine; Piperidines; Potassium Channels; Receptor, Muscarinic M3; Receptors, Muscarinic; Time Factors | 1999 |
Muscarinic cholinoceptor subtypes mediating tracheal smooth muscle contraction and inositol phosphate generation in guinea pig and rat.
Topics: Animals; Atropine; Diamines; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Trachea | 1999 |
Cardiovascular response to the injection of acetylcholine into the anterior cingulate region of the medial prefrontal cortex of unanesthetized rats.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Dose-Response Relationship, Drug; Gyrus Cinguli; Hemodynamics; Injections; Male; Muscarinic Antagonists; Occipital Lobe; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar | 1999 |
Effect of cholinergic drugs on the concentration of intracellular free calcium of rat pituitary intermediate lobe cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Atropine; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Cytosol; Female; Male; Melanocytes; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar; Vasodilator Agents | 1999 |
M2 muscarinic receptor subtype in the feline medial pontine reticular formation modulates the amount of rapid eye movement sleep.
Topics: Animals; Bethanechol; Cats; Diamines; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pons; Receptors, Muscarinic; Respiration; Reticular Formation; Sleep, REM; Time Factors; Wakefulness | 1999 |
Muscarinic receptor heterogeneity in follicle-enclosed Xenopus oocytes.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Gene Expression; Membrane Potentials; Muscarinic Antagonists; Oocytes; Ovarian Follicle; Oxotremorine; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tropicamide; Xenopus laevis | 1999 |
Selective iNOS inhibition attenuates acetylcholine- and bradykinin-induced vasoconstriction in lipopolysaccharide-exposed rat lungs.
Topics: Acetylcholine; Animals; Bradykinin; Dexamethasone; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Lipopolysaccharides; Lung; Lysine; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Piperidines; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vasoconstriction | 1999 |
Muscarinic--but not nicotinic--acetylcholine receptors mediate a nitric oxide-dependent dilation in brain cortical arterioles: a possible role for the M5 receptor subtype.
Topics: Acetylcholine; Animals; Arterioles; Cattle; Cerebral Cortex; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Humans; Microcirculation; Muscarinic Antagonists; Nitric Oxide; Organ Culture Techniques; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M5; Receptors, Muscarinic; Receptors, Nicotinic; Vasodilation; Vasodilator Agents | 2000 |
Acetylcholine modulates respiratory pattern: effects mediated by M3-like receptors in preBötzinger complex inspiratory neurons.
Topics: Acetylcholine; Animals; Animals, Newborn; Carbachol; Electrophysiology; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Respiratory Mechanics; Synapses; Tetrodotoxin | 2000 |
Role of muscarinic cholinergic transmission in Edinger-Westphal nucleus-induced choroidal vasodilation in pigeon.
Topics: Alkaloids; Animals; Atropine; Blood Pressure; Choroid; Columbidae; Electric Stimulation; Furans; Heart Rate; Muscarinic Antagonists; Naphthalenes; Parasympatholytics; Piperidines; Receptors, Muscarinic; Regional Blood Flow; Vasodilation | 2000 |
Involvement of M3 muscarinic receptors of the spinal cord in formalin-induced nociception in mice.
Topics: Acetylcholine; Animals; Atropine; Cholinergic Agents; Cholinesterase Inhibitors; Formaldehyde; Hemicholinium 3; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neostigmine; Nociceptors; Pain; Pain Measurement; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic; Spinal Cord | 2000 |
Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.
Topics: Acetylcholine; Animals; Atropine; Blood Proteins; Blotting, Western; Bradykinin; Calcium; Calcium Channels; Cells, Cultured; Diamines; Dogs; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscarinic Antagonists; Muscle, Smooth; Oxazoles; Parasympatholytics; Phenotype; Piperidines; Pirenzepine; Receptor, Muscarinic M3; Receptors, Bradykinin; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; Trachea; Vasodilator Agents | 2000 |
M(2)/M(4)-muscarinic receptors mediate automodulation of acetylcholine outflow from mouse cortex.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Autoreceptors; Binding, Competitive; Cerebral Cortex; Furans; Male; Mice; Muscarinic Antagonists; Naphthalenes; Neostigmine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic | 2000 |
Presynaptic muscarinic facilitation of parasympathetic neurotransmission after sympathectomy in the rat choroid.
Topics: Animals; Bethanechol; Choroid; Electric Stimulation; Enzyme Inhibitors; Female; Ganglionectomy; Imidazoles; Muscarinic Agonists; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Parasympathetic Nervous System; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Presynaptic; Regional Blood Flow; Salivary Glands; Superior Cervical Ganglion; Synaptic Transmission; Time Factors | 2000 |
Myenteric neurons activate submucosal vasodilator neurons in guinea pig ileum.
Topics: Animals; Arterioles; Calcium; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Ileum; Intestinal Mucosa; Magnesium; Myenteric Plexus; Neurons; Parasympatholytics; Piperidines; Reflex; Serotonin; Tetrodotoxin; Vasodilation | 2000 |
Carbachol and acetylcholine delay the early postdenervation depolarization of muscle fibres through M1-cholinergic receptors.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Carbachol; Culture Techniques; Diaphragm; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Muscle Denervation; Muscle Fibers, Skeletal; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic | 2000 |
Coordinated transitions in neurotransmitter systems for the initiation and propagation of spontaneous retinal waves.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Atropine; Bungarotoxins; Calcium; Curare; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Hexamethonium; Membrane Potentials; Muscarine; Muscarinic Antagonists; Neurotransmitter Agents; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Rabbits; Retina; Retinal Ganglion Cells | 2000 |
Influence of gender and the oestrous cycle on in vitro contractile responses of the rat urinary bladder to cholinergic stimulation.
Topics: Animals; Carbachol; Cholinergic Agonists; Diamines; Electric Stimulation; Estrus; Female; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Sex Characteristics; Time Factors; Urinary Bladder; Uterine Contraction | 2000 |
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle.
Topics: Acetylcholine; Animals; Calcium; Cattle; Cromakalim; Diamines; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical; Tetraethylammonium; Trachea | 2000 |
Neural pathways regulating Brunner's gland secretion in guinea pig duodenum in vitro.
Topics: Animals; Brunner Glands; Capsaicin; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Duodenum; Electric Stimulation; Female; Ganglia, Sympathetic; Guanethidine; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Neural Pathways; Neurotransmitter Agents; Nicotinic Agonists; Nicotinic Antagonists; Piperidines; Submucous Plexus; Substance P; Sympatholytics; Tetrodotoxin; Vagotomy; Vagus Nerve | 2000 |
Human esophageal smooth muscle cells express muscarinic receptor subtypes M(1) through M(5).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium Signaling; Cells, Cultured; Diamines; DNA Primers; Esophagus; Humans; Immunohistochemistry; Muscarinic Antagonists; Muscle Fibers, Skeletal; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptor, Muscarinic M5; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilator Agents | 2000 |
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Membranes; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pyrrolidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Tritium; Urinary Bladder | 2000 |
Depletion of phosphatidylinositol 4,5-bisphosphate by activation of phospholipase C-coupled receptors causes slow inhibition but not desensitization of G protein-gated inward rectifier K+ current in atrial myocytes.
Topics: Acetylcholine; Electric Conductivity; Endothelin-1; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Heart Atria; Ion Channel Gating; Muscarinic Antagonists; Phenylephrine; Phosphatidylinositol 4,5-Diphosphate; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Cell Surface; Receptors, Endothelin; Receptors, Muscarinic; Type C Phospholipases | 2001 |
Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Bronchi; Dexamethasone; Dose-Response Relationship, Drug; Exocrine Glands; Female; Gene Expression; Glucocorticoids; Humans; Leukocyte Elastase; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Proteinase Inhibitory Proteins, Secretory; Proteins; Respiratory Mucosa; RNA, Messenger; Secretory Leukocyte Peptidase Inhibitor; Trachea | 2001 |
A dose-response study of anticholinesterase drugs on contractile and phosphatidylinositol responses of rat trachea.
Topics: Animals; Carbachol; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Edrophonium; In Vitro Techniques; Inositol Phosphates; Isometric Contraction; Male; Muscarinic Antagonists; Muscle, Smooth; Neostigmine; Phosphatidylinositols; Piperidines; Pyridostigmine Bromide; Rats; Rats, Wistar; Stimulation, Chemical; Trachea | 2001 |
M3 muscarinic receptors but not M2 mediate contraction of the porcine detrusor muscle in vitro.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Urinary Bladder | 2000 |
Mechanisms of acetylcholine-induced vasorelaxation in high K+-stimulated rabbit renal arteries.
Topics: Acetylcholine; Animals; Atropine; Calcium; Calcium Channel Blockers; Cations, Monovalent; Endothelium, Vascular; Gadolinium; Imidazoles; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Rabbits; Renal Artery; Tropicamide; Vasoconstriction; Vasodilation | 2001 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trachea | 2001 |
Effects of cholinergic agents on the vasopressin-mediated water transport in the isolated toad bladder.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Atropine; Biological Transport; Bufo marinus; Calcium; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; In Vitro Techniques; Isotonic Solutions; Lanthanum; Osmolar Concentration; Piperidines; Pirenzepine; Urinary Bladder; Vasoconstrictor Agents; Water | 2001 |
The role of cholinergic and peptidergic pathways in the regulation of pancreatic exocrine function during postnatal development in pigs.
Topics: Amylases; Animals; Animals, Suckling; Bombesin; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinergic Fibers; Chymotrypsin; Eating; Milk; Muscarinic Antagonists; Pancreas; Pancreatic Juice; Parasympathetic Fibers, Postganglionic; Piperidines; Postprandial Period; Swine; Trypsin; Weaning | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pilocarpine; Piperidines; Receptors, Muscarinic; Urinary Bladder | 2001 |
Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists.
Topics: Alcuronium; Allosteric Regulation; Animals; CHO Cells; Cricetinae; Muscarinic Antagonists; N-Methylscopolamine; Piperidines; Radioligand Assay; Strychnine; Tritium | 2001 |
Characterization of muscarinic acetylcholine receptors in the rat epididymis.
Topics: Animals; Atropine; Cell Membrane; Diamines; Epididymis; Male; Muscarinic Antagonists; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and/or selective M3 inactivation.
Topics: Animals; Cyclic AMP; Diamines; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Piperidines; Potassium Chloride; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Urinary Bladder | 2002 |
Coupling of M(2) muscarinic receptors to Src activation in cultured canine colonic smooth muscle cells.
Topics: Animals; Atropine; Cells, Cultured; Colon; Dogs; Female; Gene Expression Regulation, Enzymologic; Genistein; Male; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Pyrazoles; Pyrimidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; src-Family Kinases; Teprotide | 2002 |
Cholinergic and serotonergic activities are required in triggering conditioned NK cell response.
Topics: Acetylcholine; Animals; Female; Gallamine Triethiodide; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Parasympathetic Nervous System; Piperidines; Poly I-C; Receptors, Muscarinic; Receptors, Serotonin; Serotonin | 2002 |
Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland.
Topics: Amylases; Animals; Atropine; Binding, Competitive; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Parotid Gland; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Specific Pathogen-Free Organisms | 2002 |
[The effects of the antagonists of muscarinic acetylcholine receptor subtypes in rat brain on urinary bladder contraction].
Topics: Animals; Atropine; Brain; Female; Muscarine; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder; Urination | 2002 |
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
Topics: Acetylcholine; Analysis of Variance; Androstadienes; Animals; Aorta; Atropine; Cell Line; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Female; Free Radical Scavengers; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Hydroxy Acids; Ionophores; Ischemic Preconditioning; Male; Methacholine Chloride; Microscopy, Fluorescence; Muscarinic Agonists; Muscle, Smooth, Vascular; Perfusion; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Potassium Channel Blockers; Potassium Channels; Protein-Tyrosine Kinases; Rabbits; Rats; Reactive Oxygen Species; Receptors, Cholinergic; Signal Transduction; Tiopronin; Valinomycin; Wortmannin | 2002 |
Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus.
Topics: Acetylcholine; Bronchi; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lung Neoplasms; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptors, Muscarinic | 2002 |
Studies of muscarinic receptor subtypes in salivary gland function in anaesthetized rats.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Diamines; Dose-Response Relationship, Drug; Drug Interactions; Female; Muscarinic Antagonists; Parotid Gland; Phentolamine; Piperidines; Pirenzepine; Propranolol; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Saliva; Salivary Glands; Sublingual Gland; Submandibular Gland; Vasodilator Agents | 2002 |
Release of acetylcholine by Die-Huang-Wan to enhance insulin secretion for lowering plasma glucose in Wistar rats.
Topics: Acetylcholine; Administration, Oral; Animals; Blood Glucose; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Hemicholinium 3; Insulin; Insulin Secretion; Male; Muscarinic Antagonists; Neuromuscular Depolarizing Agents; Physostigmine; Piperidines; Rats; Rats, Wistar | 2002 |
The colon-selective spasmolytic otilonium bromide inhibits muscarinic M(3) receptor-coupled calcium signals in isolated human colonic crypts.
Topics: Acetylcholine; Animals; Atropine; Calcium; Calcium Signaling; CHO Cells; Colon; Cricetinae; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Quaternary Ammonium Compounds; Receptor, Muscarinic M3; Receptors, Muscarinic; Time Factors; Vasodilator Agents | 2002 |
Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors.
Topics: Animals; Atropine; Central Nervous System; Cholinesterase Inhibitors; Cholinesterases; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Piperidines; Pirenzepine; Pyramidal Cells; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Receptors, Nicotinic; Soman; Synaptic Transmission | 2003 |
Cholinergic mechanism in the lateral septal area is involved in the stress-induced blood pressure increase in rats.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Epinephrine; GABA Agonists; Injections, Intraventricular; Male; Muscarinic Antagonists; Muscimol; Norepinephrine; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Restraint, Physical; Septal Nuclei; Stress, Physiological | 2003 |
Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle.
Topics: Animals; Cattle; Cells, Cultured; Drug Synergism; Inositol Phosphates; Methacholine Chloride; Mitosis; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Platelet-Derived Growth Factor; Receptor, Muscarinic M3; Receptors, Muscarinic; Thymidine; Trachea | 2003 |
Erk1/2- and p38 MAP kinase-dependent phosphorylation and activation of cPLA2 by m3 and m2 receptors.
Topics: Acetylcholine; Animals; cdc42 GTP-Binding Protein; Cells, Cultured; Enzyme Activation; GTP-Binding Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phospholipase D; Phospholipases A; Phosphorylation; Piperidines; Protein Serine-Threonine Kinases; Rabbits; rac1 GTP-Binding Protein; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Serine; Signal Transduction | 2003 |
[Cardiac-hemodynamic effects of M3 receptor agonist on rat and rabbit hearts].
Topics: Animals; Choline; Female; Heart; Heart Rate; Hemodynamics; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Rabbits; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 2001 |
Change in muscarinic modulation of transmitter release in the rat urinary bladder after spinal cord injury.
Topics: Animals; Atropine; Electric Stimulation; Female; Muscarinic Antagonists; Neurotransmitter Agents; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Spinal Cord Injuries; Urinary Bladder; Urinary Bladder, Neurogenic | 2003 |
The M4 muscarinic receptor-selective effects on keratinocyte crawling locomotion.
Topics: Animals; Atropine; Cell Movement; Humans; Infant, Newborn; Keratinocytes; Mice; Mice, Knockout; Muscarine; Muscarinic Agonists; Piperidines; Pirenzepine; Receptor, Muscarinic M4; Receptors, Muscarinic; Stimulation, Chemical | 2003 |
Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig.
Topics: Animals; Base Sequence; Carbachol; Cations; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Gastric Mucosa; Guinea Pigs; Ion Channels; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptors, Muscarinic; Stomach | 2003 |
Brain muscarinic receptor subtypes mediating water intake and Fos following cerebroventricular administration of bethanecol in rats.
Topics: Animals; Atropine; Bethanechol; Dose-Response Relationship, Drug; Drinking Behavior; Injections, Intraventricular; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Water | 2003 |
A mechanism for rapacuronium-induced bronchospasm: M2 muscarinic receptor antagonism.
Topics: Animals; Atracurium; Binding, Competitive; Bronchial Spasm; Cell Membrane; CHO Cells; Cricetinae; Diamines; Indicators and Reagents; Muscarinic Antagonists; Neuromuscular Nondepolarizing Agents; Piperidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Vecuronium Bromide | 2003 |
CCK regulates pancreatic enzyme secretion via short duodenal-pancreatic reflexes in pigs.
Topics: Animals; Benzodiazepines; Cholecystokinin; Duodenum; Muscarinic Antagonists; Pancreas; Pancreatic Juice; Piperidines; Receptor, Cholecystokinin A; Receptor, Muscarinic M3; Receptors, Cholecystokinin; Receptors, Muscarinic; Reflex; Swine; Trypsin | 2003 |
Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.
Topics: Analgesics, Opioid; Animals; Atropine; Diamines; Male; Mecamylamine; Medulla Oblongata; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Time Factors | 2003 |
Activation of mitogen-activated protein kinase by cholinergic agonists and EGF in human compared with rat cultured conjunctival goblet cells.
Topics: Adult; Aged; Aged, 80 and over; Animals; Blotting, Western; Carbachol; Cells, Cultured; Cholinergic Agonists; Conjunctiva; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Goblet Cells; Humans; Male; Middle Aged; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Time Factors; Tyrphostins | 2003 |
Castration decreases amylase release associated with muscarinic acetylcholine receptor downregulation in rat parotid gland.
Topics: Amylases; Animals; Binding, Competitive; Carbachol; Cholinergic Agonists; Down-Regulation; Inositol Phosphates; Male; Orchiectomy; Parotid Gland; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic | 2003 |
Activation of muscarinic receptors in rat subfornical organ neurones.
Topics: Acetylcholine; Animals; Choline O-Acetyltransferase; Gold Colloid; Immunohistochemistry; Male; Membrane Potentials; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neural Pathways; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Subfornical Organ; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; Wheat Germ Agglutinins | 2003 |
Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol.
Topics: Astrocytes; Astrocytoma; Atropine; Blotting, Western; Carbachol; Cell Line; Cellular Structures; Central Nervous System Depressants; Chelating Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Ethanol; Gallamine Triethiodide; Humans; Muscarinic Antagonists; NF-kappa B; Nicotinic Antagonists; Pertussis Toxin; Piperidines; Receptors, Muscarinic; Thymidine; Time Factors; Tritium | 2003 |
Projections from the caudal part to the rostral part of the lateral septal area mediate blood pressure increase.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Fluorescent Dyes; GABA Agonists; Hypertension; Male; Microinjections; Muscarinic Antagonists; Muscimol; Neural Pathways; Neurons; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reaction Time; Septum of Brain; Stress, Physiological | 2003 |
Long vasodilator reflexes projecting through the myenteric plexus in guinea-pig ileum.
Topics: Androstadienes; Animals; Arterioles; Catheterization; Denervation; Female; Guinea Pigs; Ileum; Intestinal Mucosa; Male; Microvilli; Myenteric Plexus; Neurons; Parasympatholytics; Piperidines; Reflex; Tetrodotoxin; Vasodilation; Wortmannin | 2003 |
Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src.
Topics: Acetylcholine; Animals; Barium; Calcium Channels, L-Type; Carbazoles; Cells, Cultured; Chromones; Class Ib Phosphatidylinositol 3-Kinase; Diamines; Enzyme Inhibitors; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Indoles; Ion Channel Gating; Ion Transport; Isoenzymes; Male; Morpholines; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Portal Vein; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Signal Transduction | 2004 |
Regulation of rat mesencephalic GABAergic neurones through muscarinic receptors.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neural Inhibition; Neurons; Piperidines; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Synapses | 2004 |
Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea.
Topics: Animals; Antiemetics; Carbachol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Metoclopramide; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphatidylinositols; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Muscarinic M3; Trachea | 2004 |
Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation.
Topics: Animals; Bethanechol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Enteric Nervous System; Female; Gastroparesis; In Vitro Techniques; Indoles; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Piperidines; Potassium; Receptors, Muscarinic; Serotonin; Serotonin Receptor Agonists; Stomach | 2004 |
Effects of anticholinergic drugs selective for muscarinic receptor subtypes on prepulse inhibition in mice.
Topics: Animals; Cholinergic Antagonists; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic; Reflex, Startle; Scopolamine; Tropicamide | 2004 |
Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill.
Topics: Adenylyl Cyclase Inhibitors; Animals; Arecoline; Atropine; Carbachol; Colforsin; Cyclic AMP; Cytoplasmic Granules; Light; Muscarinic Agonists; Muscarinic Antagonists; Perciformes; Pigment Epithelium of Eye; Piperidines; Pirenzepine; Quaternary Ammonium Compounds; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Retinal Pigments; Second Messenger Systems; Tropicamide | 2004 |
Functional characterization of muscarinic receptor subtypes in human duodenal secretion.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Acetylcholine; Bumetanide; Calcium Channel Blockers; Diuretics; Duodenum; Elapid Venoms; Humans; Intercellular Signaling Peptides and Proteins; Ion Transport; Muscarinic Antagonists; Neurotoxins; ortho-Aminobenzoates; Peptides; Piperidines; Receptors, Muscarinic | 2004 |
[Relationship between M3 receptor and myocyte apoptosis induced by acute myocardial infarction].
Topics: Animals; Apoptosis; Choline; fas Receptor; Male; Malondialdehyde; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Piperidines; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Tumor Necrosis Factor; Superoxide Dismutase | 2004 |
Alterations in the muscarinic M1 and M3 receptor gene expression in the brain stem during pancreatic regeneration and insulin secretion in weanling rats.
Topics: Acetylcholinesterase; Adrenal Glands; Animals; Blood Glucose; Body Weight; Brain Stem; Chromatography, High Pressure Liquid; DNA Primers; Electrochemistry; Epinephrine; Insulin; Kinetics; Muscarinic Antagonists; Norepinephrine; Pancreas; Pancreatectomy; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; Thymidine | 2004 |
Comparison of the antimuscarinic action of p-fluorohexahydrosiladifenidol in ileal and tracheal smooth muscle.
Topics: Animals; Atropine; Cattle; Guinea Pigs; Histamine Antagonists; Hydrolysis; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Piperidines; Receptor, Muscarinic M3; Trachea | 2005 |
Arecoline excites the colonic smooth muscle motility via M3 receptor in rabbits.
Topics: Animals; Arecoline; Atropine; Colon; Dose-Response Relationship, Drug; Female; Ganglionic Stimulants; Gastrointestinal Motility; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Piperidines; Rabbits; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2004 |
Characterization of functional effects of Z-338, a novel gastroprokinetic agent, on the muscarinic M1, M2, and M3 receptors expressed in Xenopus oocytes.
Topics: Acetylcholine; Animals; Benzamides; Dose-Response Relationship, Drug; Female; Gastrointestinal Agents; Gene Expression; Humans; Membrane Potentials; Muscarinic Antagonists; Oocytes; Piperidines; Pirenzepine; Potassium; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Reproducibility of Results; Thiazoles; Xenopus | 2004 |
Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analgesics; Animals; Atropine; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Diamines; Injections, Spinal; Male; Mice; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Pain; Pain Threshold; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Spinal Cord; Streptozocin; Stress, Mechanical; Time Factors | 2004 |
Regional differences in cholinergic regulation of potassium current in feline esophageal circular smooth muscle.
Topics: Acetylcholine; Animals; Cats; Electrophysiology; Esophagus; Membrane Potentials; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Pirenzepine; Potassium Channels; Receptor, Muscarinic M3 | 2005 |
Signal transduction underlying carbachol-induced PGE2 generation and cox-1 mRNA expression of rat brain.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Cyclooxygenase 1; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Frontal Lobe; Gene Expression Regulation; Male; Membrane Proteins; Models, Biological; Muscarinic Antagonists; Nitric Oxide Synthase; Phosphatidylinositols; Piperidines; Pirenzepine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2005 |
M3-R/IK(M3)--a new target of antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Separation; Choline; Guinea Pigs; Heart Ventricles; Male; Myocytes, Cardiac; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3 | 2005 |
[The role of a type of m-choline receptors in realization of vagal influences on cardiac rhythm and conduction].
Topics: Animals; Cats; Electrocardiography; Heart Conduction System; Heart Rate; Myocardial Contraction; Parasympatholytics; Piperidines; Receptors, Cholinergic; Vagus Nerve | 2005 |
The anti-inflammatory effect of peripheral bee venom stimulation is mediated by central muscarinic type 2 receptors and activation of sympathetic preganglionic neurons.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Atropine; Autonomic Fibers, Preganglionic; Bee Venoms; Catecholamines; Cell Count; Choline O-Acetyltransferase; Disease Models, Animal; Drug Interactions; Exudates and Transudates; Hexamethonium; Immunohistochemistry; Inflammation; Leukocytes; Male; Mice; Mice, Inbred ICR; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Oncogene Proteins v-fos; Oxidopamine; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Spinal Cord; Sympathectomy, Chemical | 2005 |
Neuronal nitric oxide synthase activity in rat urinary bladder detrusor: participation in M3 and M4 muscarinic receptor function.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase Type I; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Tritium; Tropicamide; Urinary Bladder | 2005 |
Postjunctional modulation by muscarinic M2 receptors of responses to electrical field stimulation of rat detrusor muscle preparations.
Topics: Animals; Diamines; Electric Stimulation; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Propranolol; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Theophylline; Time Factors; Urinary Bladder; Vasodilator Agents | 2005 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicardipine; Pertussis Toxin; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2005 |
Neural regulation of slow-wave frequency in the murine gastric antrum.
Topics: Acetylcholine; Androstenes; Animals; Atropine; Benzamides; Benzimidazoles; Carbachol; Electric Stimulation; Electrophysiology; Enteric Nervous System; Female; Gastric Emptying; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Motor Neurons; Muscle Contraction; Myenteric Plexus; Neostigmine; Piperidines; Pyloric Antrum; Tetrodotoxin | 2006 |
Spinal muscarinic and nicotinic subtypes activated by clonidine in postincisional pain.
Topics: Aconitine; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Diamines; Dihydro-beta-Erythroidine; Injections, Spinal; Male; Muscarinic Agonists; Nicotinic Agonists; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Nicotinic; Spine | 2005 |
Muscarinic M1 and M3 receptor binding alterations in pancreas during pancreatic regeneration of young rats.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Muscarinic Antagonists; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Regeneration | 2005 |
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine.
Topics: Animals; Carbachol; Cations; Cholinergic Agonists; Diamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Guinea Pigs; In Vitro Techniques; Intestine, Small; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Mice; Muscarinic Antagonists; Myocytes, Smooth Muscle; Pertussis Toxin; Piperidines; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Type C Phospholipases | 2006 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
Release of glutamate by the embryonic spinal motoneurons of rat positively regulated by acetylcholine through the nicotinic and muscarinic receptors.
Topics: Acetylcholine; Animals; Buffers; Calcium; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Immunohistochemistry; Motor Neurons; Piperidines; Pregnancy; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Spinal Cord | 2006 |
Agonist and antagonist sensitivity of non-selective cation channel currents evoked by muscarinic receptor stimulation in bovine ciliary muscle cells.
Topics: Animals; Atropine; Barium; Carbachol; Cattle; Cells, Cultured; Ciliary Body; Dose-Response Relationship, Drug; Membrane Potentials; Microscopy, Fluorescence; Muscarinic Agonists; Muscarinic Antagonists; Muscle Cells; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptor, Muscarinic M3; TRPC Cation Channels | 2006 |
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction.
Topics: Animals; Benzilates; Binding, Competitive; Calcium; Carbachol; Cell Line; Cells, Cultured; CHO Cells; Cholinergic Antagonists; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electric Stimulation; Epithelial Cells; Humans; Molecular Structure; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Potassium Chloride; Receptors, Muscarinic; Urinary Bladder | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Fundus; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Physostigmine; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Stomach | 2007 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
Muscarinic receptor subtypes mediating positive and negative inotropy in the developing chick ventricle.
Topics: Action Potentials; Alkaloids; Animals; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Furans; Heart Ventricles; Myocardial Contraction; Naphthalenes; Piperidines; Pirenzepine; Receptors, Muscarinic | 2007 |
Autonomic involvement in the permanent metabolic programming of hyperinsulinemia in the high-carbohydrate rat model.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Autonomic Nervous System; Cholinergic Agents; Dietary Carbohydrates; Female; Glucose; Glucose Tolerance Test; Hyperinsulinism; Insulin; Muscarinic Antagonists; Oxymetazoline; Piperidines; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Vagotomy; Yohimbine | 2007 |
In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cyclophosphamide; Cystitis; Diamines; Electric Stimulation; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Phentolamine; Piperidines; Pirenzepine; Propranolol; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Suramin; Sympatholytics; Urinary Bladder | 2007 |
Cardiovascular effects of carbachol microinjected into the bed nucleus of the stria terminalis of the rat brain.
Topics: Animals; Arginine Vasopressin; Atropine; Blood Pressure; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Male; Microinjections; Muscarinic Antagonists; Nicotinic Antagonists; Pentolinium Tartrate; Piperidines; Rats; Rats, Wistar; Septal Nuclei | 2007 |
In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows.
Topics: Animals; Bethanechol; Cattle; Dairying; Dose-Response Relationship, Drug; Duodenum; Female; In Vitro Techniques; Jejunum; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Tropicamide | 2007 |
Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Atropine; Benzophenanthridines; Dose-Response Relationship, Drug; Female; Fish Venoms; Glycoproteins; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Muscarinic Antagonists; Myocytes, Cardiac; Patch-Clamp Techniques; Pinacidil; Piperidines; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Protein Kinase Inhibitors; Receptor, Muscarinic M3; Signal Transduction; Time Factors | 2007 |
Cardiac activity and blood pressure in rats during selective blockade of various subtypes of muscarinic cholinoceptors.
Topics: Animals; Blood Pressure; Electric Stimulation; Electrocardiography; Gallamine Triethiodide; Heart Rate; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Time Factors; Vagus Nerve | 2006 |
Endocannabinoids mediate muscarine-induced synaptic depression at the vertebrate neuromuscular junction.
Topics: Animals; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Drug Interactions; Endocannabinoids; Enzyme Inhibitors; Inhibitory Postsynaptic Potentials; Lizards; Models, Biological; Morpholines; Muscarine; Muscarinic Agonists; Neuromuscular Junction; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1 | 2007 |
Muscarinic receptor-independent activation of cyclic adenosine monophosphate-dependent protein kinase in rostral ventrolateral medulla underlies the sympathoexcitatory phase of cardiovascular responses during mevinphos intoxication in the rat.
Topics: Animals; Atropine; Blotting, Western; Cardiovascular System; Cholinesterase Inhibitors; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Male; Medulla Oblongata; Mevinphos; Muscarinic Antagonists; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Time Factors; Tropicamide | 2007 |
Roles of muscarinic receptor subtypes in small intestinal motor dysfunction in acute radiation enteritis.
Topics: Animals; Diamines; Enteritis; Gastrointestinal Motility; Ileum; Male; Manometry; Piperidines; Pirenzepine; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 2007 |
Increase in cochlear microphonic potential after toluene administration.
Topics: Acoustic Stimulation; Animals; Atropine; Cholinergic Antagonists; Cochlea; Cochlear Microphonic Potentials; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Gentamicins; Neurons, Efferent; Noise; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Reflex, Acoustic; Solvents; Toluene | 2007 |
Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system.
Topics: Animals; Arecoline; Benzofurans; Carbachol; Cholinergic Agonists; Female; Guinea Pigs; Muscarinic Agonists; Piperidines; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder; Urination | 2007 |
Functional expression of M3, a muscarinic acetylcholine receptor subtype, in taste bud cells of mouse fungiform papillae.
Topics: Acetylcholine; Animals; Atropine; Calcium Signaling; Cells, Cultured; Diamines; Electrophysiology; Gene Expression; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Patch-Clamp Techniques; Phospholipase C beta; Piperidines; Pirenzepine; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomal-Associated Protein 25; Taste Buds; Tropicamide; Vesicular Acetylcholine Transport Proteins | 2008 |
Subtype-selective blockade of cardiac muscarinic receptors inhibits vagal chronotropic responses in cats.
Topics: Animals; Cats; Diamines; Electrocardiography; Female; Gallamine Triethiodide; Heart; Heart Rate; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Vagus Nerve | 2008 |
Anti-brain cholinergic auto antibodies from primary Sjögren syndrome sera modify simultaneously cerebral nitric oxide and prostaglandin biosynthesis.
Topics: Adult; Animals; Autoantibodies; Cerebral Cortex; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression; Humans; Immunoglobulin G; Male; Membrane Proteins; Middle Aged; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Phospholipase A2 Inhibitors; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 2007 |
Changes in muscarinic receptors in the toad urothelial cell line TBM-54 following acrolein treatment.
Topics: Acrolein; Animals; Blotting, Western; Bufo marinus; Carbachol; Cell Line; Diamines; Dose-Response Relationship, Drug; Extracellular Fluid; Hydrogen-Ion Concentration; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2008 |
Cholinergic innervation of the guinea-pig isolated vas deferens.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Bretylium Compounds; Calcium; Cholinesterase Inhibitors; Cyclopentolate; Guinea Pigs; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Myocytes, Smooth Muscle; Neostigmine; Nicotine; Nicotinic Agonists; Piperidines; Receptors, Muscarinic; Vas Deferens; Yohimbine | 2007 |
Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism.
Topics: Acetylcholine; Bronchi; Cell Line, Transformed; Chemotaxis, Leukocyte; Epithelial Cells; Flavonoids; Gallamine Triethiodide; Humans; Indoles; Interleukin-8; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscarinic Antagonists; Neutrophils; NF-kappa B; Nitriles; Piperidines; Pirenzepine; Protein Kinase C; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives; Sulfones; Tiotropium Bromide | 2008 |
Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats.
Topics: Acetylcholine; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Eleutherococcus; Glucosides; Insulin; Insulin Secretion; Male; Muscarinic Antagonists; Phenylpropionates; Phytotherapy; Piperidines; Rats; Receptor, Muscarinic M3 | 2008 |
Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Cells, Cultured; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ipratropium; Male; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Neostigmine; Petasites; Piperidines; Protein Binding; Receptor, Muscarinic M3; Sesquiterpenes; Time Factors; Trachea | 2008 |
Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux.
Topics: Animals; Atropine; Capillary Permeability; Diamines; Female; Ganglionic Blockers; Gastroesophageal Reflux; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Receptors, Nicotinic; Regional Blood Flow; Respiratory System | 2008 |
Loss of [3H]4-DAMP binding to muscarinic receptors in the orbitofrontal cortex of Alzheimer's disease patients with psychosis.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; CHO Cells; Cohort Studies; Cricetinae; Cricetulus; Female; Humans; Longitudinal Studies; Male; Muscarinic Antagonists; Neocortex; Neurofibrillary Tangles; Neuropsychological Tests; Piperidines; Psychotic Disorders; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic; Synapses; Transfection | 2008 |
M3 cholinergic receptors are involved in postnatal development of cholinergic regulation of cardiac activity in rats.
Topics: Animals; Blood Pressure; Cholinergic Fibers; Heart; Heart Rate; Muscarinic Antagonists; Piperidines; Rats; Receptor, Muscarinic M3; Vagus Nerve | 2007 |
Involvement of the lymphocytic muscarinic acetylcholine receptor in methylmercury-induced c-Fos expression and apoptosis in human leukemic T cells.
Topics: Apoptosis; Drug Interactions; Genes, fos; Humans; Jurkat Cells; Methylmercury Compounds; Muscarinic Antagonists; Piperidines; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tumor Cells, Cultured | 2008 |
Refractoriness of the sheep superior vena cava myocardial sleeve.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Diamines; Electrophysiologic Techniques, Cardiac; In Vitro Techniques; Microelectrodes; Muscarinic Antagonists; Myocardium; Myocytes, Cardiac; Piperidines; Refractometry; Sheep; Tropicamide; Vasodilator Agents; Vena Cava, Superior | 2008 |
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Antineoplastic Agents; Atropine; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Electric Stimulation; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Physostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Suramin; Urinary Bladder | 2008 |
Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: involvement of the cholinergic pathway.
Topics: Animals; Animals, Newborn; Antigens, Neoplasm; Biomarkers, Tumor; Carbachol; Carrier Proteins; Immunoblotting; In Vitro Techniques; Insulin; Islets of Langerhans; Lectins, C-Type; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatitis-Associated Proteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases | 2008 |
Levels of [(3)H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1.
Topics: Adult; Aged; Autoradiography; Binding Sites; Cathepsin B; Cerebral Cortex; Female; Humans; Male; Middle Aged; Piperidines; Pirenzepine; Radioligand Assay; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Schizophrenia; Sp1 Transcription Factor | 2008 |
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake.
Topics: Animals; Blood Pressure; Diamines; Drinking Behavior; Heart Rate; Hypertension; Injections, Intraventricular; Male; Muscarinic Antagonists; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Saliva; Tropicamide | 2008 |
[Role of ventricular M3 receptor in arrhythmia resulted from cerebral-cardiac syndrome].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Choline; Electrocardiography; Heart Ventricles; Infarction, Middle Cerebral Artery; Male; Muscarinic Antagonists; Myocardium; Myocytes, Cardiac; Piperidines; Potassium Chloride; Random Allocation; Rats; Rats, Wistar; Receptor, Muscarinic M3 | 2008 |
Choline produces antiarrhythmic actions in animal models by cardiac M3 receptors: improvement of intracellular Ca2+ handling as a common mechanism.
Topics: Aconitine; Animals; Arrhythmias, Cardiac; Calcium; Choline; Disease Models, Animal; Female; Guinea Pigs; Male; Myocytes, Cardiac; Ouabain; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3 | 2008 |
Spinal cholinergic mechanism of the relieving effects of electroacupuncture on cold and warm allodynia in a rat model of neuropathic pain.
Topics: Animals; Atropine; Cholinergic Agents; Cholinergic Fibers; Cold Temperature; Diamines; Disease Models, Animal; Electroacupuncture; Hot Temperature; Hyperesthesia; Male; Mecamylamine; Neuralgia; Pain Threshold; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Spinal Nerves | 2009 |
Muscarinic receptor-mediated nitric oxide release in a K562 erythroleukaemia cell line.
Topics: Arginine; Carbachol; Chromatography, High Pressure Liquid; Citrulline; Dose-Response Relationship, Drug; Humans; K562 Cells; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tropicamide | 2009 |
Muscarinic receptor antagonism at the spinal cord level causes inhibitory effects on male rat sexual behavior.
Topics: Animals; Diamines; Injections, Spinal; Male; Muscarinic Antagonists; Piperidines; Rats; Rats, Wistar; Rotarod Performance Test; Sexual Behavior, Animal; Spinal Cord; Tropicamide | 2009 |
Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.
Topics: Animals; Anti-Inflammatory Agents; Biological Clocks; Calcium; Calcium-Transporting ATPases; Carbachol; Cation Transport Proteins; Cells, Cultured; Diamines; Flufenamic Acid; Guanosine Diphosphate; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred BALB C; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Piperidines; Plant Roots; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Thapsia; Thapsigargin; Thionucleotides | 2009 |
High spatial resolution studies of muscarinic neuroeffector junctions in mouse isolated vas deferens.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Antagonists; Age Factors; Animals; Calcium; Cholinesterase Inhibitors; Cyclopentolate; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Muscle Contraction; Muscle, Smooth; Neostigmine; Neuroeffector Junction; Neurons; Norepinephrine; Piperidines; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha-2; Vas Deferens; Yohimbine | 2009 |
An increase in intracelluar free calcium ions modulated by cholinergic receptors in rat facial nucleus.
Topics: Acetylcholine; Aniline Compounds; Animals; Brain Stem; Calcium; Diamines; Facial Nerve; Female; Fluorescent Dyes; In Vitro Techniques; Male; Microscopy, Confocal; Motor Neurons; Muscarinic Agonists; Nicotine; Nicotinic Agonists; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Tropicamide; Xanthenes | 2009 |
Salivation triggered by pilocarpine involves aquaporin-5 in normal rats but not in irradiated rats.
Topics: Animals; Aquaporin 5; Calcium; Male; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Pilocarpine; Piperidines; Protein Transport; Radiation Injuries, Experimental; Radioligand Assay; Rats; Rats, Sprague-Dawley; Saliva; Salivation; Whole-Body Irradiation; Xerostomia | 2009 |
The antiarrhythmic effect and possible ionic mechanisms of pilocarpine on animal models.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Disease Models, Animal; Female; Guinea Pigs; Male; Microscopy, Confocal; Muscarinic Agonists; Muscarinic Antagonists; Myocytes, Cardiac; Ouabain; Pilocarpine; Piperidines; Rats; Rats, Wistar; Receptor, Muscarinic M3; Time Factors | 2009 |
Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anal Canal; Animals; Autoantibodies; Benzofurans; Bethanechol; Case-Control Studies; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulins; In Vitro Techniques; Male; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Myocytes, Smooth Muscle; Phenylephrine; Piperidines; Potassium Chloride; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Scleroderma, Systemic | 2009 |
Dual radiotracer analysis of cholinergic neuronal changes in prediabetic mouse pancreas.
Topics: Animals; Fluorine Radioisotopes; Fluorobenzenes; Insulin-Secreting Cells; Mice; Pancreas; Parasympatholytics; Piperidines; Prediabetic State; Radiography; Tritium | 2009 |
Opening of ATP-sensitive potassium channel by insulin in the brain-induced insulin secretion in Wistar rats.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Brain; Glyburide; Hypoglycemic Agents; Injections, Intravenous; Injections, Intraventricular; Insulin; KATP Channels; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Piperidines; Potassium Channel Blockers; Rats; Rats, Wistar; Vagotomy | 2010 |
Distinct roles of cholinergic receptors in small cell lung cancer cells.
Topics: Blotting, Western; Carcinoma, Small Cell; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cholinergic Agonists; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Muscarinic Antagonists; Piperidines; Polysaccharides; Receptor, Muscarinic M3; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Effects of pilocarpine and cevimeline on Ca2+ mobilization in rat parotid acini and ducts.
Topics: Animals; Calcium; Calcium Signaling; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Pilocarpine; Piperidines; Quinuclidines; Rats; Receptors, Muscarinic; Thiophenes | 2009 |
Cholinergic autoantibodies from primary Sjögren's syndrome modulate submandibular gland Na+/K+-ATPase activity via prostaglandin E2 and cyclic AMP.
Topics: Adult; Animals; Autoantibodies; Cells, Cultured; Cyclic AMP; Dinoprostone; Female; Humans; Immunoglobulin G; Immunologic Factors; Inflammation Mediators; Keratoconjunctivitis Sicca; Male; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Piperidines; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptor, Muscarinic M3; Sjogren's Syndrome; Sodium-Potassium-Exchanging ATPase; Submandibular Gland; Tropicamide; Xerostomia | 2010 |
M₃muscarinic receptors mediate acetylcholine-induced pulmonary vasodilation in pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Diamines; Hypertension, Pulmonary; Lung; Piperidines; Pirenzepine; Rabbits; Receptor, Muscarinic M3; Vasodilation | 2010 |
Activation of M3 muscarinic receptors inhibits T-type Ca(2+) channel currents via pertussis toxin-sensitive novel protein kinase C pathway in small dorsal root ganglion neurons.
Topics: Animals; Calcium Channels, T-Type; Calcium Signaling; Cholera Toxin; Cobra Neurotoxin Proteins; Estrenes; Ganglia, Spinal; Indoles; Maleimides; Mice; Mice, Inbred ICR; Muscarinic Antagonists; Neurons; Pain Measurement; Pertussis Toxin; Piperidines; Protein Kinase C; Pyrrolidinones; Receptor, Muscarinic M3; Type C Phospholipases | 2011 |
Plasticity of non-adrenergic non-cholinergic bladder contractions in rats after chronic spinal cord injury.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neuronal Plasticity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Spinal Cord Injuries; Urinary Bladder | 2011 |
Muscarinic activation of Ca2+-activated Cl- current in interstitial cells of Cajal.
Topics: Animals; Atropine; Carbachol; Chloride Channels; Green Fluorescent Proteins; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Receptors, Muscarinic | 2011 |
Expression of muscarinic receptors by human macrophages.
Topics: Carbachol; Cells, Cultured; Choline O-Acetyltransferase; Humans; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Leukotriene B4; Macrophages; Membrane Transport Proteins; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pulmonary Disease, Chronic Obstructive; Receptors, Muscarinic; RNA; Smoking; Vesicular Acetylcholine Transport Proteins | 2012 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Effects of neostigmine on bronchoconstriction with continuous electrical stimulation in rats.
Topics: Animals; Asthma; Bronchoconstriction; Electric Stimulation; Male; Neostigmine; Parasympathomimetics; Piperidines; Rats; Rats, Wistar; Tetrodotoxin; Trachea | 2012 |
Activation of M3 muscarinic receptor and Ca²⁺ influx by crude fraction from Crotonis Fructus in isolated rabbit jejunum.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Croton; Female; Fruit; In Vitro Techniques; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Plant Extracts; Rabbits; Receptor, Muscarinic M3; Solvents; Verapamil | 2012 |
Functional M3 cholinoreceptors are present in pacemaker and working myocardium of murine heart.
Topics: Action Potentials; Animals; Diamines; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Pilocarpine; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sinoatrial Node | 2012 |
Inhibition of stretching-evoked ATP release from bladder mucosa by anticholinergic agents.
Topics: Adenosine Triphosphate; Animals; Biomechanical Phenomena; Diamines; Guinea Pigs; In Vitro Techniques; Male; Mucous Membrane; Muscarinic Antagonists; Piperidines; Urinary Bladder; Urothelium | 2012 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder | 2012 |
Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2012 |
Role of various subtypes of muscarinic cholinergic receptors in the development of posthemorrhagic abnormalities in systemic and portal circulation in rats.
Topics: Animals; Blood Circulation; Blood Pressure; Hemorrhage; Hypotension; Male; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Tropicamide | 2012 |
Role of M3 mAChR in in vivo and in vitro models of LPS-induced inflammatory response.
Topics: Acute Lung Injury; Animals; Atropine; Cell Line; Lipopolysaccharides; Macrophages, Alveolar; Male; Mice; Muscarinic Antagonists; NF-kappa B; Piperidines; Pneumonia; Receptor, Muscarinic M3 | 2012 |
Peculiar effects of muscarinic M1, M2, and M3 receptor blockers on cardiac chronotropic function in neonatal rats.
Topics: Animals; Animals, Newborn; Gallamine Triethiodide; Heart Rate; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Stimulation, Chemical; Vagus Nerve | 2012 |
Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbachol; Cattle; Cholinergic Agonists; Ciliary Body; Endocannabinoids; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Polyunsaturated Alkamides; Protein Kinase C; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Muscarinic M3; rho-Associated Kinases | 2013 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide | 2013 |
Effect of selective stimulation of muscarinic M3 cholinoceptors on electrical and contractile activity of rat ventricular myocardium.
Topics: Action Potentials; Animals; Diamines; Heart; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; Myocardium; Parasympatholytics; Pilocarpine; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Ventricular Function | 2013 |
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases.
Topics: Aged; Atropine; Benzofurans; Carbachol; Cell Proliferation; Cells, Cultured; Cholinergic Agonists; Gene Expression; Humans; Male; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptors, Muscarinic; RNA, Messenger; Urinary Bladder | 2013 |
Activation of muscarinic M3 receptors inhibits large-conductance voltage- and Ca2+-activated K+ channels in rat urinary bladder smooth muscle cells.
Topics: Amphotericin B; Animals; Carbachol; Cholinergic Agonists; Diamines; Evoked Potentials; Gene Expression Regulation; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscarinic Antagonists; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Urinary Bladder | 2013 |
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sjogren's Syndrome; Stomach | 2013 |
The use of a modified [3H]4-DAMP radioligand binding assay with increased selectivity for muscarinic M3 receptor shows that cortical CHRM3 levels are not altered in mood disorders.
Topics: Adult; Aged; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Humans; Mice; Mice, Knockout; Middle Aged; Mood Disorders; Muscarinic Antagonists; Piperidines; Pirenzepine; Protein Binding; Radioligand Assay; Radionuclide Imaging; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic; Tritium | 2013 |
Cyclic GMP regulates M₃AChR activity at plasma membranes from airway smooth muscle.
Topics: Animals; Cattle; Cell Membrane; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type II; Feedback, Physiological; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Protein Processing, Post-Translational; Quinuclidinyl Benzilate; Receptors, Muscarinic; Signal Transduction; Trachea | 2013 |
mAChRs activation induces epithelial-mesenchymal transition on lung epithelial cells.
Topics: Cells, Cultured; Epithelial Cells; Epithelial-Mesenchymal Transition; Humans; Lung; Piperidines; Receptors, Muscarinic; Respiratory Mucosa; Transforming Growth Factor beta1 | 2014 |
Expression and function of muscarinic subtype receptors in bladder interstitial cells of cajal in rats.
Topics: Action Potentials; Animals; Atropine; Calcium Channels; Carbachol; Cholinergic Agonists; Diamines; Interstitial Cells of Cajal; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |
An investigation of the factors that regulate muscarinic receptor expression in schizophrenia.
Topics: Adult; Blotting, Western; Brain; Cohort Studies; Humans; Middle Aged; Piperidines; Pirenzepine; Polymerase Chain Reaction; Radioligand Assay; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic; RNA, Messenger; Schizophrenia; Sp1 Transcription Factor; Sp3 Transcription Factor; Tritium | 2014 |
An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats.
Topics: Acetylcholine; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cholinesterase Inhibitors; Enzyme Inhibitors; Extracellular Space; Long-Term Synaptic Depression; Male; MAP Kinase Kinase Kinases; Muscarinic Antagonists; p38 Mitogen-Activated Protein Kinases; Physostigmine; Piperidines; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Synapses; Tissue Culture Techniques | 2014 |
In vitro effects of the organophosphorus pesticide malathion on the reactivity of rat aorta.
Topics: Animals; Aorta, Thoracic; Atropine; Endothelium, Vascular; Epoprostenol; Gallamine Triethiodide; In Vitro Techniques; Indomethacin; Malathion; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pesticides; Phenylephrine; Piperidines; Pirenzepine; Rats, Wistar; Vasodilator Agents | 2014 |
Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway.
Topics: Administration, Intravenous; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Choline; Cholinergic Agonists; Dose-Response Relationship, Drug; Ischemia; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Reperfusion Injury; Signal Transduction; Structure-Activity Relationship; Vascular System Injuries | 2015 |
Different Myocardial Sensitivity in Newborn and Mature Rats to Selective Stimulation of M3 Cholinoreceptors.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Diamines; Heart Atria; Heart Ventricles; Male; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Piperidines; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2015 |
Acetylcholine ameliorates endoplasmic reticulum stress in endothelial cells after hypoxia/reoxygenation via M3 AChR-AMPK signaling.
Topics: Acetylcholine; AMP-Activated Protein Kinases; Apoptosis; Caspase 12; Cell Hypoxia; Cell Line; DNA Nucleotidylexotransferase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Piperidines; Protein Serine-Threonine Kinases; Receptor, Muscarinic M3; Reperfusion Injury; RNA Interference; RNA, Small Interfering; Signal Transduction; Transcription Factor CHOP | 2015 |
Selective Monoesterification of Symmetrical Diols Using Resin-Bound Triphenylphosphine.
Topics: Amides; Esters; Indicators and Reagents; Organophosphorus Compounds; Piperidines | 2015 |
Effects of Dangkwisoo‑san, a traditional herbal medicine for treating pain and blood stagnation, on the pacemaker activities of cultured interstitial cells of Cajal.
Topics: Animals; Calcium-Transporting ATPases; Cells, Cultured; Diamines; Female; Gastrointestinal Motility; Guanosine Diphosphate; Interstitial Cells of Cajal; Intestine, Small; Male; Mice; Mice, Inbred BALB C; Pain; Phytotherapy; Piperidines; Plants, Medicinal; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Thapsigargin; Thionucleotides | 2015 |
Excitatory drive from the Subthalamic nucleus attenuates GABAergic transmission in the Substantia Nigra pars compacta via endocannabinoids.
Topics: Animals; Carbachol; Chromones; Dopaminergic Neurons; Electric Stimulation; Endocannabinoids; Excitatory Postsynaptic Potentials; GABAergic Neurons; Inhibitory Postsynaptic Potentials; Pars Compacta; Pars Reticulata; Piperidines; Pyrazoles; Rats; Rimonabant; Subthalamic Nucleus; Synaptic Transmission | 2015 |
Changes in cholinergic and glutamatergic markers in the striatum from a sub-set of subjects with schizophrenia.
Topics: Autoradiography; Blotting, Western; Corpus Striatum; Disks Large Homolog 4 Protein; Female; Glial Fibrillary Acidic Protein; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; Muscarinic Antagonists; Neuroglia; Neurons; Piperidines; Pirenzepine; Radioligand Assay; Radiopharmaceuticals; Receptors, Muscarinic; Schizophrenia; Synaptosomal-Associated Protein 25; Tritium | 2015 |
Muscarinic acetylcholine receptor M1 and M3 subtypes mediate acetylcholine-induced endothelium-independent vasodilatation in rat mesenteric arteries.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Endothelium, Vascular; Hexamethonium; In Vitro Techniques; Male; Mesenteric Arteries; Piperidines; Pirenzepine; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Vasodilation | 2016 |
[M3 Muscarnic Receptor Antagonist Mediates Cell Proliferation Apoptosis
and Adhesion in Small Cell Lung Cancer].
Topics: Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Piperidines; Receptor, Muscarinic M3; Small Cell Lung Carcinoma | 2016 |
Characterization of muscarinic and P2X receptors in the urothelium and detrusor muscle of the rat bladder.
Topics: Animals; Cyclophosphamide; Diterpenes; Imidazoles; Male; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Purinergic P2X Receptor Antagonists; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic P2X; Urinary Bladder; Urothelium | 2016 |
Muscarinic cholinergic receptor antagonists in the VTA and RMTg have opposite effects on morphine-induced locomotion in mice.
Topics: Acetylcholine; Animals; Atropine; Locomotion; Mice; Mice, Inbred C57BL; Morphine; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Tropicamide; Ventral Tegmental Area | 2017 |
Arecoline Promotes Migration of A549 Lung Cancer Cells through Activating the EGFR/Src/FAK Pathway.
Topics: Arecoline; Cell Line, Tumor; Cell Movement; ErbB Receptors; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M3; Signal Transduction; src-Family Kinases | 2019 |
Novel choline analog 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol produces sympathoinhibition, hypotension, and antihypertensive effects.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Atropine; Blood Pressure; Heart Rate; Hypertension; Hypotension; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperazines; Piperidines; Pirenzepine; Pyrazoles; Rats, Inbred SHR; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3 | 2019 |
Pilocarpine induces the residual secretion of salivary fluid in perfused submandibular glands of rats.
Topics: Animals; Male; Muscarinic Antagonists; Oxygen Consumption; Perfusion; Pilocarpine; Piperidines; Rats, Wistar; Saliva; Submandibular Gland; Tetrodotoxin | 2019 |
Central muscarinic receptor subtypes (M1 and M3) involved in carbacol-induced hypophagia in neonatal broiler chicken.
Topics: Animals; Animals, Newborn; Behavior, Animal; Carbachol; Chickens; Disease Models, Animal; Eating; Injections, Intraventricular; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M3 | 2020 |
Balanced cholinergic modulation of spinal locomotor circuits via M2 and M3 muscarinic receptors.
Topics: Acetylcholine; Action Potentials; Animals; Animals, Newborn; Diamines; In Vitro Techniques; Locomotion; Mice; Mice, Inbred C57BL; Motor Neurons; Muscarine; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Spinal Cord | 2019 |
Rewarding effects of M4 but not M3 muscarinic cholinergic receptor antagonism in the rostromedial tegmental nucleus.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Dopamine Antagonists; Flupenthixol; Locomotion; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Reward; Tropicamide; Ventral Tegmental Area | 2020 |