Compounds > 4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide
Page last updated: 2024-09-03

4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide and nintedanib

4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide has been researched along with nintedanib in 3 studies

Compound Research Comparison

Studies
(4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide)		Trials
(4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide)		Recent Studies (post-2010)
(4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide)		Studies
(nintedanib)		Trials
(nintedanib)		Recent Studies (post-2010) (nintedanib)
62014846133801

Protein Interaction Comparison

ProteinTaxonomy4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide (IC50)nintedanib (IC50)
Platelet-derived growth factor receptor betaMus musculus (house mouse)0.085
Tyrosine-protein kinase LckHomo sapiens (human)0.016
Tyrosine-protein kinase LynHomo sapiens (human)0.1483
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0133
Fibroblast growth factor receptor 1Homo sapiens (human)0.068
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.1093
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.017
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.0395
Fibroblast growth factor receptor 2Homo sapiens (human)0.037
Fibroblast growth factor receptor 4Homo sapiens (human)0.61
Fibroblast growth factor receptor 3Homo sapiens (human)0.108
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)0.085
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.0116
Vascular endothelial growth factor receptor 2Mus musculus (house mouse)0.013
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.009
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.026
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.0026
Maternal embryonic leucine zipper kinaseHomo sapiens (human)0.043

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

3 other study(ies) available for 4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide and nintedanib

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020