Compounds > 4-desmethoxyverapamil
Page last updated: 2024-09-02

4-desmethoxyverapamil and gallopamil

4-desmethoxyverapamil has been researched along with gallopamil in 4 studies

Compound Research Comparison

Studies
(4-desmethoxyverapamil)		Trials
(4-desmethoxyverapamil)		Recent Studies (post-2010)
(4-desmethoxyverapamil)		Studies
(gallopamil)		Trials
(gallopamil)		Recent Studies (post-2010) (gallopamil)
76011,1488821

Protein Interaction Comparison

ProteinTaxonomy4-desmethoxyverapamil (IC50)gallopamil (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.011
ATP-dependent translocase ABCB1Homo sapiens (human)3.2
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.023
Voltage-dependent L-type calcium channel subunit alpha-1DRattus norvegicus (Norway rat)0.023
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.011
Voltage-dependent L-type calcium channel subunit alpha-1SRattus norvegicus (Norway rat)0.023
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.011
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.014

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fosset, M; Galizzi, JP; Lazdunski, M1
Bradford, HF; White, EJ1
Degtiar, VE; Döring, F; Glossman, H; Grabner, M; Hering, S; Striessnig, J1
Catterall, WA; Hockerman, GH; Johnson, BD; Scheuer, T1

Other Studies

4 other study(ies) available for 4-desmethoxyverapamil and gallopamil

ArticleYear
Characterization of the Ca2+ coordination site regulating binding of Ca2+ channel inhibitors d-cis-diltiazem, (+/-)bepridil and (-)desmethoxyverapamil to their receptor site in skeletal muscle transverse tubule membranes.
    Biochemical and biophysical research communications, 1985, Oct-15, Volume: 132, Issue:1

    Topics: Barium; Benzazepines; Bepridil; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Kinetics; Magnesium; Membranes; Microtubules; Muscles; Pyrrolidines; Receptors, Nicotinic; Strontium; Verapamil

1985
Participation of intracellular sites in the action of Ca2+ channel blockers.
    European journal of pharmacology, 1986, Nov-04, Volume: 130, Issue:3

    Topics: Amino Acids; Animals; Calcium Channel Blockers; Calcium Radioisotopes; Cerebral Cortex; Gallopamil; In Vitro Techniques; Potassium; Rats; Synaptosomes; Verapamil; Veratrine

1986
Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.
    The Journal of biological chemistry, 1996, May-17, Volume: 271, Issue:20

    Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Calcium Channels; Gallopamil; Molecular Sequence Data; Rabbits; Structure-Activity Relationship; Verapamil; Xenopus laevis

1996
Distinct effects of mutations in transmembrane segment IVS6 on block of L-type calcium channels by structurally similar phenylalkylamines.
    Molecular pharmacology, 1996, Volume: 50, Issue:5

    Topics: Amino Acid Sequence; Aniline Compounds; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Gallopamil; Kinetics; Molecular Sequence Data; Mutation; Protein Structure, Secondary; Structure-Activity Relationship; Verapamil

1996