Compounds > 4-desmethoxyverapamil
Page last updated: 2024-09-02

4-desmethoxyverapamil and flunarizine

4-desmethoxyverapamil has been researched along with flunarizine in 2 studies

Compound Research Comparison

Studies
(4-desmethoxyverapamil)		Trials
(4-desmethoxyverapamil)		Recent Studies (post-2010)
(4-desmethoxyverapamil)		Studies
(flunarizine)		Trials
(flunarizine)		Recent Studies (post-2010) (flunarizine)
76011,269189153

Protein Interaction Comparison

ProteinTaxonomy4-desmethoxyverapamil (IC50)flunarizine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.669
Bile salt export pumpHomo sapiens (human)10
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)0.49
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.339
Muscarinic acetylcholine receptor M4Homo sapiens (human)5.656
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.107
Alpha-2A adrenergic receptorHomo sapiens (human)0.581
Adenosine receptor A3Homo sapiens (human)5.198
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.936
Cytochrome P450 2C9 Homo sapiens (human)0.94
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.6058
D(2) dopamine receptorHomo sapiens (human)0.352
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.198
Alpha-2B adrenergic receptorHomo sapiens (human)1.893
Alpha-2C adrenergic receptorHomo sapiens (human)0.222
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.281
Muscarinic acetylcholine receptor M3Homo sapiens (human)1.479
Cannabinoid receptor 1Homo sapiens (human)3.028
D(1A) dopamine receptorHomo sapiens (human)3.874
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.339
Alpha-1D adrenergic receptorHomo sapiens (human)1.085
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.407
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.669
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.281
Sodium-dependent serotonin transporterHomo sapiens (human)0.499
Delta-type opioid receptorMus musculus (house mouse)1.67
Histamine H1 receptorHomo sapiens (human)0.158
Mu-type opioid receptorHomo sapiens (human)5.236
D(3) dopamine receptorHomo sapiens (human)0.097
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.088
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.198
Cytochrome P450 2J2Homo sapiens (human)0.8833
Voltage-dependent L-type calcium channel subunit beta-1Rattus norvegicus (Norway rat)0.08
Voltage-dependent calcium channel subunit alpha-2/delta-1Rattus norvegicus (Norway rat)0.08
D(2) dopamine receptorRattus norvegicus (Norway rat)0.228
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)1.67
Sodium-dependent dopamine transporter Homo sapiens (human)0.584
Voltage-dependent N-type calcium channel subunit alpha-1BRattus norvegicus (Norway rat)0.08
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.6058
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.6058
Potassium channel subfamily K member 2 Bos taurus (cattle)2.5
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.025
Prostaglandin D2 receptor 2Homo sapiens (human)0.08

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carvalho, AP; Carvalho, CM; Leysen, JE; Lima, MP; Oliveira, CR1
Carvalho, CM; Lopes, MC; Santos, DL1

Other Studies

2 other study(ies) available for 4-desmethoxyverapamil and flunarizine

ArticleYear
Partition of Ca2+ antagonists in brain plasma membranes.
    Biochemical pharmacology, 1989, Jul-01, Volume: 38, Issue:13

    Topics: Animals; Brain; Calcium Channel Blockers; Flunarizine; Kinetics; Liposomes; Nitrendipine; Sheep; Synaptic Membranes; Verapamil

1989
Calcium channel blockers inhibit the (Ca2+ + Mg2+)-ATPase activity and the 125I-calmodulin binding in brain membranes.
    European journal of pharmacology, 1994, May-17, Volume: 267, Issue:3

    Topics: Animals; Autoradiography; Binding Sites; Brain; Ca(2+) Mg(2+)-ATPase; Calcium Channel Blockers; Calmodulin; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Flunarizine; Iodine Radioisotopes; Nitrendipine; Sheep; Stereoisomerism; Synaptic Membranes; Trifluoperazine; Verapamil

1994