4-chlorothreonine and 3-hydroxyaspartic-acid

Several authors' changes should have been included in the response by D. B. Wheeler et al. to the technical comment "Identification of calcium channels that control neurosecretion" (4 Nov., p. 830). A sentence reading, "Comparisons with experiments using higher concentrations of carrier protein (1.0 mg/mL) revealed no significant differences in the rate of efficacy of omega-Aga-IVA action" should have been inserted before the last sentence in the legend of figure 1. The measure "30 nM" (not 20 nM) should have appeared 19 lines from the bottom of the last column on page 830. The second-to-last sentence in that paragraph should read, "Increasing the duration of exposure to 30 nM omega-Aga-IVA from 20 min (1) to 45 min revealed significant inhibition of synaptic transmission (n = 9)." Reference "(15)" (not 16) should have appeared seven lines from the top of the first column on page 831.

Topics: Aspartic Acid; Bacterial Proteins; Peptide Biosynthesis; Peptides; Pseudomonas; Threonine