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4-chlorophenylbiguanide and pyrimethamine

4-chlorophenylbiguanide has been researched along with pyrimethamine in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cichero, E; Espinoza, S; Gainetdinov, RR; Tonelli, M1
Cichero, E; Costi, MP; Gazzarrini, S; Loddo, R; Moroni, A; Naesens, L; Santucci, M; Tasso, B; Tonelli, M1
Chulay, JD; Sixsmith, DG; Watkins, WM1

Other Studies

3 other study(ies) available for 4-chlorophenylbiguanide and pyrimethamine

ArticleYear
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Absorption, Physicochemical; Animals; Biguanides; Chemistry Techniques, Synthetic; Computer Simulation; Drug Design; Humans; Mice; Molecular Docking Simulation; Protein Conformation; Receptors, G-Protein-Coupled; Structure-Activity Relationship

2017
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Antiviral Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Proguanil; Respiratory Syncytial Viruses; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2017
The activity of proguanil and its metabolites, cycloguanil and p-chlorophenylbiguanide, against Plasmodium falciparum in vitro.
    Annals of tropical medicine and parasitology, 1984, Volume: 78, Issue:3

    Topics: Animals; Biguanides; Chloroquine; Microbial Sensitivity Tests; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines

1984