4-chloro-3-hydroxyanthranilic acid has been researched along with kynurenic acid in 4 studies
| Studies (4-chloro-3-hydroxyanthranilic acid) | Trials (4-chloro-3-hydroxyanthranilic acid) | Recent Studies (post-2010) (4-chloro-3-hydroxyanthranilic acid) | Studies (kynurenic acid) | Trials (kynurenic acid) | Recent Studies (post-2010) (kynurenic acid) |
|---|---|---|---|---|---|
| 20 | 0 | 2 | 2,611 | 28 | 750 |
| Protein | Taxonomy | 4-chloro-3-hydroxyanthranilic acid (IC50) | kynurenic acid (IC50) |
|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | 7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, CY; Heyes, MP; Markey, SP; Naritsin, DB; Saito, K | 1 |
| Heyes, MP; Major, EO; Markey, SP; Milstien, S; Saito, K; Vickers, JH | 1 |
| Guidetti, P; Schwarcz, R; Wu, HQ | 1 |
| Blight, AR; Heyes, MP; Yates, JR | 1 |
4 other study(ies) available for 4-chloro-3-hydroxyanthranilic acid and kynurenic acid
| Article | Year |
|---|---|
Metabolism of L-tryptophan to kynurenate and quinolinate in the central nervous system: effects of 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cell Line; Central Nervous System; Gas Chromatography-Mass Spectrometry; Humans; Kynurenic Acid; Kynurenine; Lyases; Macaca mulatta; Quinolinic Acid; Transaminases; Tryptophan | 1995 |
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biopterins; Brain; Encephalitis; Fetus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Macaca mulatta; Myelitis; Neopterin; Poliomyelitis; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1993 |
In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biotransformation; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Infusions, Parenteral; Kynurenic Acid; Kynurenine; Male; Malonates; Neurons; Neuroprotective Agents; Prodrugs; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glycine | 2000 |
4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury.
Topics: 3-Hydroxyanthranilic Acid; Algorithms; Animals; Behavior, Animal; Blood-Brain Barrier; Female; Guinea Pigs; Kynurenic Acid; Myelin Sheath; Permeability; Proprioception; Quinolinic Acid; Reference Standards; Reflex, Monosynaptic; Spinal Cord Compression; Spinal Cord Injuries | 2006 |