4-chloro-2-(2-imidazolin-2-ylamino)isoindoline and phenoxybenzamine

4-chloro-2-(2-imidazolin-2-ylamino)isoindoline has been researched along with phenoxybenzamine in 2 studies

Compound Research Comparison

Studies (4-chloro-2-(2-imidazolin-2-ylamino)isoindoline)	Trials (4-chloro-2-(2-imidazolin-2-ylamino)isoindoline)	Recent Studies (post-2010) (4-chloro-2-(2-imidazolin-2-ylamino)isoindoline)	Studies (phenoxybenzamine)	Trials (phenoxybenzamine)	Recent Studies (post-2010) (phenoxybenzamine)
12	0	1	5,006	70	95

Protein Interaction Comparison

Protein	Taxonomy	phenoxybenzamine (IC50)
Solute carrier family 22 member 2	Homo sapiens (human)	4.9
Solute carrier family 22 member 1	Homo sapiens (human)	2.72
Solute carrier family 22 member 3	Homo sapiens (human)	6.13

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (50.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Göthert, M; Molderings, GJ	1
Thoolen, MJ; Timmermans, PB	1

Other Studies

2 other study(ies) available for 4-chloro-2-(2-imidazolin-2-ylamino)isoindoline and phenoxybenzamine

Article	Year
Involvement of presynaptic imidazoline receptors in the alpha 2-adrenoceptor-independent inhibition of noradrenaline release by imidazoline derivatives. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:3 Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Drug Interactions; Electric Stimulation; Imidazoles; Imidazoline Receptors; Isoindoles; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Drug; Receptors, Neurotransmitter; Tritium; Yohimbine	1991
Equal potency of nifedipine to inhibit alpha 1-(dobutamine and BDF 6143) and alpha 2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine. European journal of pharmacology, 1987, Aug-11, Volume: 140, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Decerebrate State; Dobutamine; Dose-Response Relationship, Drug; Imidazoles; Isoindoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains	1987

Article

Year

Involvement of presynaptic imidazoline receptors in the alpha 2-adrenoceptor-independent inhibition of noradrenaline release by imidazoline derivatives.

Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:3

Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Drug Interactions; Electric Stimulation; Imidazoles; Imidazoline Receptors; Isoindoles; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Rabbits; Receptors, Drug; Receptors, Neurotransmitter; Tritium; Yohimbine

1991

Equal potency of nifedipine to inhibit alpha 1-(dobutamine and BDF 6143) and alpha 2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine.

European journal of pharmacology, 1987, Aug-11, Volume: 140, Issue:2

Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Decerebrate State; Dobutamine; Dose-Response Relationship, Drug; Imidazoles; Isoindoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains

1987