Compounds > 4-chloro-2-(2-imidazolin-2-ylamino)isoindoline
Page last updated: 2024-09-03

4-chloro-2-(2-imidazolin-2-ylamino)isoindoline and oxymetazoline

4-chloro-2-(2-imidazolin-2-ylamino)isoindoline has been researched along with oxymetazoline in 2 studies

Compound Research Comparison

Studies
(4-chloro-2-(2-imidazolin-2-ylamino)isoindoline)		Trials
(4-chloro-2-(2-imidazolin-2-ylamino)isoindoline)		Recent Studies (post-2010)
(4-chloro-2-(2-imidazolin-2-ylamino)isoindoline)		Studies
(oxymetazoline)		Trials
(oxymetazoline)		Recent Studies (post-2010) (oxymetazoline)
1201738128159

Protein Interaction Comparison

ProteinTaxonomy4-chloro-2-(2-imidazolin-2-ylamino)isoindoline (IC50)oxymetazoline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.578
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.261
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.332
Alpha-2A adrenergic receptorHomo sapiens (human)0.023
Cytochrome P450 2D6Homo sapiens (human)0.2
Alpha-2B adrenergic receptorHomo sapiens (human)1.273
Alpha-2C adrenergic receptorHomo sapiens (human)2.633
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0056
Alpha-1D adrenergic receptorHomo sapiens (human)2.844
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.285
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.578
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0056
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.056
5-hydroxytryptamine receptor 6Homo sapiens (human)1.67

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agbaba, D; Filipic, S; Nikolic, K1
Göthert, M; Molderings, GJ1

Other Studies

2 other study(ies) available for 4-chloro-2-(2-imidazolin-2-ylamino)isoindoline and oxymetazoline

ArticleYear
QSAR study of imidazoline antihypertensive drugs.
    Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15

    Topics: Antihypertensive Agents; Binding Sites; Imidazoline Receptors; Imidazolines; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship

2008
Inhibitory presynaptic imidazoline receptors on sympathetic nerves in the rabbit aorta differ from I1- and I2-imidazoline binding sites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:5

    Topics: Agmatine; Animals; Aorta; Binding Sites; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Imidazoline Receptors; Isoindoles; Male; Norepinephrine; Oxymetazoline; Potassium; Pulmonary Artery; Rabbits; Receptors, Drug; Sympathetic Nervous System

1995