Page last updated: 2024-08-18

4-butyrolactone and thiophenes

4-butyrolactone has been researched along with thiophenes in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's1 (8.33)18.2507
2000's3 (25.00)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Santiago, M; Westerink, BH1
De Vries, JB; Horn, AS; Tepper, PG; Van der Weide, J1
Aquino, M; Bruno, I; Gomez-Paloma, L; Guerrero, MD; Paya, M; Riccio, R; Terencio, MC1
Bernasconi, CF; Sato, M; Yamataka, H; Yoshimura, N1
Aquino, M; Bruno, I; Guerrero, MD; Payá, M; Riccio, R; Terencio, MC1
Andrés, RM; Aquino, M; Bruno, I; De Simone, R; Guerrero, MD; Paya, M; Riccio, R; Terencio, MC1
Christman, JW; van Breemen, RB; Xiao, L; Yu, R; Zhao, G1
Chen, XG; Huang, WB; Jia, RP; Li, WC; Qian, M; Wu, JP; Xu, LW; Xu, Z1
Cao, H; Christman, JW; Deng, J; Li, Y; Ornatowska, M; Sadikot, RT; Xiao, L; Yu, R; Zhao, G; Zhao, Q1
Ariza, X; Garcia, J; Lloyd-Williams, P; Martínez-Laporta, A; Sánchez, C; Santos, D1
Boonmars, T; Chusorn, P; Jongthawin, J; Khuntikeo, N; Loilome, W; Namwat, N; Puapairoj, A; Tassaneeyakul, W; Techasen, A; Thanan, R; Yongvanit, P1
Bhupathiraju, NVSDK; Gonzalez Periche, P; Johnson, DS; Kalidindi, T; Mootoo, DR; Pillarsetty, N; Ramdular, A1

Other Studies

12 other study(ies) available for 4-butyrolactone and thiophenes

ArticleYear
Characterization and pharmacological responsiveness of dopamine release recorded by microdialysis in the substantia nigra of conscious rats.
    Journal of neurochemistry, 1991, Volume: 57, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Consciousness; Corpus Striatum; Dialysis; Dopamine; Dopamine Agents; Injections, Intraperitoneal; Male; Microchemistry; Nomifensine; Perfusion; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Sulpiride; Tetrahydronaphthalenes; Tetrodotoxin; Thiophenes

1991
Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734.
    European journal of pharmacology, 1986, Jun-17, Volume: 125, Issue:2

    Topics: 4-Butyrolactone; alpha-Methyltyrosine; Animals; Brain; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Female; Male; Methyltyrosines; Mice; Naphthalenes; Norepinephrine; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Stereotyped Behavior; Tetrahydronaphthalenes; Thiophenes; Time Factors

1986
Synthesis and pharmacological evaluation of a selected library of new potential anti-inflammatory agents bearing the gamma-hydroxybutenolide scaffold: a new class of inhibitors of prostanoid production through the selective modulation of microsomal prosta
    Journal of medicinal chemistry, 2007, May-03, Volume: 50, Issue:9

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Combinatorial Chemistry Techniques; Cyclooxygenase 2; Dinoprostone; Female; Furans; Humans; Intramolecular Oxidoreductases; Mice; Microsomes; NF-kappa B; Phospholipases A; Phospholipases A2; Prostaglandin Antagonists; Prostaglandin-E Synthases; Structure-Activity Relationship; Thiophenes

2007
Deprotonation of 3(2H)-furanone and 3(2H)-thiophenone by carbanions in the gas phase: disproportionately high aromaticity of the transition state: an ab initio study.
    The Journal of organic chemistry, 2009, Jan-02, Volume: 74, Issue:1

    Topics: 4-Butyrolactone; Gases; Protons; Quantum Theory; Thermodynamics; Thiophenes

2009
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression.
    European journal of pharmacology, 2009, Oct-12, Volume: 620, Issue:1-3

    Topics: 4-Butyrolactone; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Behavior, Animal; Blood Platelets; Cattle; Chronic Disease; Gene Expression Regulation, Enzymologic; Humans; Hyperalgesia; Inflammation; Intramolecular Oxidoreductases; Leukotriene B4; Male; Mice; Neutrophils; Prostaglandin-E Synthases; Thiophenes; Thromboxane B2

2009
Toward the discovery of new agents able to inhibit the expression of microsomal prostaglandin E synthase-1 enzyme as promising tools in drug development.
    Chemical biology & drug design, 2010, Volume: 76, Issue:1

    Topics: 4-Butyrolactone; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Drug Discovery; Gene Expression; Intramolecular Oxidoreductases; Macrophages; Mice; Microsomes; Oleanolic Acid; Prostaglandin-E Synthases; Thiophenes

2010
Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: 4-Butyrolactone; Animals; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dibenzocycloheptenes; Dinoprostone; Enzyme Assays; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Isomerases; Lipocalins; Macrophages; Mice; Mice, Inbred C57BL; Piperidines; Prostaglandin D2; Prostaglandin H2; Prostaglandin-E Synthases; Sheep; Thiophenes

2011
Expression and significance of microsomal prostaglandin synthase-1 (mPGES-1) and Beclin-1 in the development of prostate cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4

    Topics: 4-Butyrolactone; Adenocarcinoma; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Apoptosis Regulatory Proteins; Beclin-1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chi-Square Distribution; Humans; Intramolecular Oxidoreductases; Male; Membrane Proteins; Microsomes; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prostaglandin-E Synthases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Thiophenes; Up-Regulation

2012
Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: 4-Butyrolactone; Animals; Cyclooxygenase 1; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Intramolecular Oxidoreductases; Lipocalins; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Microsomes; Nitric Oxide Synthase Type II; Primary Cell Culture; Prostaglandin D2; Prostaglandin-E Synthases; Proto-Oncogene Proteins; RNA, Small Interfering; Thiophenes; Trans-Activators

2012
Total synthesis of (-)-isoavenaciolide.
    The Journal of organic chemistry, 2013, Feb-15, Volume: 78, Issue:4

    Topics: 4-Butyrolactone; Boranes; Molecular Structure; Stereoisomerism; Thiophenes

2013
PGE2 signaling and its biosynthesis-related enzymes in cholangiocarcinoma progression.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:8

    Topics: 4-Butyrolactone; Adult; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholangiocarcinoma; Cyclooxygenase 2; Dinoprostone; Female; Humans; Intramolecular Oxidoreductases; Male; Middle Aged; Prostaglandin-E Synthases; Signal Transduction; Thiophenes

2014
Synthesis of carbohydrate analogues of the THF-acetogenin 4-deoxyannomontacin and their cytotoxicity against human prostate cancer cell lines.
    Carbohydrate research, 2022, Volume: 521

    Topics: 4-Butyrolactone; Acetogenins; Alkenes; Antineoplastic Agents; Carbohydrates; Cell Line, Tumor; Humans; Male; Mannose; Prostatic Neoplasms; Thiophenes; Trichothecenes

2022