Page last updated: 2024-08-18

4-butyrolactone and sesquiterpenes

4-butyrolactone has been researched along with sesquiterpenes in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.02)18.7374
1990's5 (8.77)18.2507
2000's24 (42.11)29.6817
2010's20 (35.09)24.3611
2020's4 (7.02)2.80

Authors

AuthorsStudies
Ashmore, JW; Kupchan, SM; Sneden, AT1
Barbier, P; Benezra, C; Ducombs, G; Stampf, JL1
Bhavanishankar, TN; Ramesh, HP; Shantha, T1
Quijano, L; Rios, T; Sabanero, M; Trejo, R1
Dölz, H; Gutierrez, E; Kesternich, V; Mansilla, H; Martínez, R1
Ando, M; Arao, K; Kataoka, T; Magae, J; Nagai, K; Nishimura, T; Otake, N; Suzuki, H; Taniguchi, M; Uramoto, M1
Ko, FN; Liao, CH; Teng, CM; Wu, TS1
Ashurmetov, O; Honda, G; Itoh, M; Kodzhimatov, OK; Su, BN; Takaishi, Y; Takeda, Y1
Back, TG; Payne, JE1
Kawahara, Y; Matsuda, H; Morikawa, T; Shimoda, H; Uemura, T; Yoshikawa, M1
Back, TG; Nava-Salgado, VO; Payne, JE1
Fuchino, H; Koide, T; Satake, M; Sekita, S; Takahashi, M1
Bhargava, A; Brohm, D; Lieb, F; Metzger, S; Müller, O; Philippe, N; Waldmann, H1
Brocksom, TJ; Coelho, F; Deprés, JP; Freire De Lima, ME; Greene, AE; Hamelin, O; Hartmann, B; Kanazawa, AM; Wang, Y1
Feng, JD; Luo, XZ; Ou, SL; Xu, LZ; Yang, SL; Yu, JG1
HIKINO, H; KUSANO, G; MEGURO, K; TAKEMOTO, T1
Reddy, DS1
Choi, BM; Chung, HT; Jang, SI; Kwon, JW; Kwon, TO; Oh, GS; Oh, H; Pae, HO; Yun, YG1
Adlington, RM; Bagal, SK; Baldwin, JE; Marquez, R1
Fong, HH; Nguyen, MC; Nguyen, VH; Pezzuto, JM; Soejarto, DD; Tan, GT; Zhang, HJ1
Deyrup, ST; Gloer, JB; Sobolev, VS1
Brocksom, TJ; Constantino, MG; Oliveira, KT; Polo, EC; Silva, GV1
Liu, JQ; Liu, SJ; Wang, ZT; Zhang, CF; Zhang, M1
Chung, HT; Jeong, GS; Jeong, SO; Kim, NS; Kim, YC; Kwon, TO; Lee, HS; Pae, HO; Park, SD1
Bhattacharyya, A; Jiang, CH; Sha, CK1
Chung, HT; Jeong, GS; Kim, HS; Kim, YC; Pae, HO; Rhew, HY; Sohn, DH; Woo, WH1
Akita, H; Kato, K; Kusakabe, T; Motodate, S; Takaishi, S1
Choi, JY; Ho Lee, S; Hyun Hwang, I; Na, M; Seog Ahn, J; Yeon Kim, B; Young Bae, E1
Bosisio, E; D'Ambrosio, M; Dell'Agli, M; Galli, GV1
Ammar, S; Bouraoui, A; Chatter, R; Edziri, H; Mahjoub, MA; Mighri, Z1
Gao, W; Guo, Y; Xu, J; Zhang, S; Zhao, X1
Duan, HQ; Tang, SA; Zhang, W1
Chen, X; Cheng, W; Fan, X; Li, Y; Shi, J; Wang, W; Xu, W; Yang, Y; Zhu, C1
Carneiro, VM; Ferraz, HM; Ishikawa, EE; Silva, LF; Vieira, TO1
Bandey, AH; Chashoo, G; Mondhe, D; Qazi, GN; Qazi, NA; Reddy, DM; Sampath Kumar, HM; Sawant, SD; Saxena, A; Saxena, AK; Sethi, VK; Shankar, M; Singh, SK; Srinivas, J; Taneja, SC; Verma, M1
Constantino, MG; Heleno, VC; Lopes, JL; Lopes, NP; Morais, GO; Sass, DC1
Amoah, SK; Biavatti, MW; Bürger, C; de Souza, MM; Gonçalves, AE; Tolardo, R1
Gao, X; Jia, G; Ma, Z; Qin, X; Ren, Y; Zhang, L; Zhou, Y1
Bian, Y; Chen, Y; Luo, T; Ren, W; Shang, H; Tang, Y; Yang, Z; Zhang, P; Zhang, Z1
He, C; Ma, G; Peng, Y; Wei, H; Xiao, P1
Bhakta, S; Evangelopoulos, D; Gibbons, S; Gupta, A; Guzman, JD; Prieto, JM1
Bifulco, G; Casapullo, A; D'Amore, C; D'Auria, MV; De Marino, S; Festa, C; Fiorucci, S; Lauro, G; Mencarelli, A; Monti, MC; Petek, S; Renga, B; Zampella, A1
Cui, J; Li, ML; Yuan, MS1
Duan, JA; Li, W; Li, Z; Liu, P; Qian, D; Shang, EX1
Amslinger, S; Ertl, T; Kerres, S; Kreuzer, A; Reiser, O; Rücker, H1
Gagare, PD; Helppi, MA; Nair, HN; Nicponski, DR; Ramachandran, PV; Schmidt, CM; Yip-Schneider, MT1
Ikegami, F; Namiki, T; Saito, Y; Sumino, M1
de Almeida, ÁS; Garruti, Ddos S; Lemos, AP; Magalhães, HC; Nobre, AC1
Becerra-Martínez, E; Joseph-Nathan, P; Olmedo-Aguirre, JO; Ortega, AR; Ortiz-Pastrana, N; Quijano, L1
Amoah, SKS; Biavatti, MW1
He, Y; Hu, Z; Li, F; Liu, M; Qi, C; Sun, W; Wang, J; Xue, Y; Zhang, J; Zhang, Y; Zhu, H1
Chen, Y; Li, S; Xu, J; Zhao, J1
Chu, MJ; Han, X; Jiang, MM; Li, GQ; Li, PL; Li, T; Luo, LZ; Luo, XC; Tang, XL; van Ofwegen, L; Zhang, G1
An, T; Cai, B; Chen, L; Duan, A; Ju, X; Kong, L; Li, X; Li, Y; Yang, Q1
Contreras, JI; Karpf, AR; Kizhake, S; Kour, S; Natarajan, A; Rana, S; Robb, CM; Sonawane, YA; Zahid, M1
Abdallah, HM; Abdel-Naim, AB; Alamoudi, AJ; Eid, BG; Ibrahim, SRM; Kammoun, AK; Mohamed, GA; Shaik, RA; Sirwi, A1
Abdallah, HM; Abdel-Naim, AB; Alamoudi, AJ; Eid, BG; Elfaky, MA; Ibrahim, SRM; Mohamed, GA; Shaik, RA; Sirwi, A1

Reviews

1 review(s) available for 4-butyrolactone and sesquiterpenes

ArticleYear
Total synthesis of sesterterpenoids.
    Natural product reports, 2019, 02-20, Volume: 36, Issue:2

    Topics: 4-Butyrolactone; Bridged Bicyclo Compounds; Molecular Structure; Sesquiterpenes; Sesterterpenes; Terpenes

2019

Other Studies

56 other study(ies) available for 4-butyrolactone and sesquiterpenes

ArticleYear
Structure-activity relationships among in vivo active germacranolides.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:6

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Leukemia, Experimental; Mice; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Sesquiterpenes; Structure-Activity Relationship

1978
Enantiospecificity in allergic contact dermatitis. A review and new results in Frullania-sensitive patients.
    Contact dermatitis, 1985, Volume: 13, Issue:2

    Topics: 4-Butyrolactone; Animals; Benzofurans; Benzoquinones; Dermatitis, Contact; Guinea Pigs; Humans; Plants; Quinones; Sesquiterpenes; Skin Tests; Stereoisomerism; Structure-Activity Relationship

1985
Dermal toxicity of Fusarium toxins in combinations.
    Archives of toxicology, 1988, Volume: 61, Issue:3

    Topics: 4-Butyrolactone; Animals; Drug Synergism; Furans; Guinea Pigs; Male; Mycotoxins; Sesquiterpenes; Skin; T-2 Toxin; Trichothecenes

1988
Encelin: a fungal growth inhibitor.
    Planta medica, 1995, Volume: 61, Issue:2

    Topics: 4-Butyrolactone; Antifungal Agents; Lactones; Mucor; Plants, Medicinal; Sesquiterpenes

1995
Conformational analysis and biological activity of leptocarpin and leptocarpin acetate.
    Planta medica, 1995, Volume: 61, Issue:2

    Topics: 4-Butyrolactone; Carbohydrate Conformation; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Plants, Medicinal; Sesquiterpenes

1995
Costunolide and dehydrocostus lactone as inhibitors of killing function of cytotoxic T lymphocytes.
    Bioscience, biotechnology, and biochemistry, 1995, Volume: 59, Issue:11

    Topics: 4-Butyrolactone; Cytotoxicity, Immunologic; Lactones; Phosphorylation; Sesquiterpenes; T-Lymphocytes, Cytotoxic; Tyrosine

1995
Bakkenolide G, a natural PAF-receptor antagonist.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Butyrolactone; Adenosine Triphosphate; Animals; Arachidonic Acid; Blood Platelets; Calcium; Collagen; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sesquiterpenes; Spiro Compounds; Thrombin; Thromboxane B2

1997
Sesquiterpene phenylpropanoid and sesquiterpene chromone derivatives from Ferula pallida.
    Journal of natural products, 2000, Volume: 63, Issue:4

    Topics: 4-Butyrolactone; Chromones; Ferula; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Plants, Medicinal; Plants, Toxic; Sesquiterpenes

2000
A concise total synthesis of (+/-)-bakkenolide A by means of an intramolecular Diels-Alder reaction.
    Organic letters, 1999, Aug-26, Volume: 1, Issue:4

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Asteraceae; Insecticides; Sesquiterpenes; Stereoisomerism

1999
Alcohol absorption inhibitors from bay leaf (Laurus nobilis): structure-requirements of sesquiterpenes for the activity.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:8

    Topics: 4-Butyrolactone; Absorption; Animals; Blood Glucose; Drugs, Chinese Herbal; Ethanol; Furans; Humans; Lactones; Lauraceae; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Plant Leaves; Rats; Rats, Wistar; Sesquiterpenes; Structure-Activity Relationship

2000
Synthesis of (+/-)-bakkenolide-A and its C-7, C-10, and C-7,10 epimers by means of an intramolecular Diels-Alder reaction.
    The Journal of organic chemistry, 2001, Jun-15, Volume: 66, Issue:12

    Topics: 4-Butyrolactone; Isomerism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Sesquiterpenes

2001
New sesquiterpene lactones from Elephantopus mollis and their leishmanicidal activities.
    Planta medica, 2001, Volume: 67, Issue:7

    Topics: 4-Butyrolactone; Animals; Antiprotozoal Agents; Asteraceae; Brazil; Inhibitory Concentration 50; Leishmania major; Magnetic Resonance Spectroscopy; Molecular Structure; Peru; Plant Extracts; Plants, Medicinal; Sesquiterpenes; Sesquiterpenes, Germacrane; Sesquiterpenes, Guaiane

2001
Solid-phase synthesis of dysidiolide-derived protein phosphatase inhibitors.
    Journal of the American Chemical Society, 2002, Nov-06, Volume: 124, Issue:44

    Topics: 4-Butyrolactone; cdc25 Phosphatases; Chemistry, Organic; Cross-Linking Reagents; Enzyme Inhibitors; Sesquiterpenes; Solutions

2002
First comprehensive bakkane approach: stereoselective and efficient dichloroketene-based total syntheses of (+/-)- and (-)-9-acetoxyfukinanolide, (+/-)- and (+)-bakkenolide A, (-)-bakkenolides III, B, C, H, L, V, and X, (+/-)- and (-)-homogynolide A, (+/-
    Journal of the American Chemical Society, 2002, Dec-25, Volume: 124, Issue:51

    Topics: 4-Butyrolactone; Cyclohexanes; Cyclohexenes; Dichloroethylenes; Petasites; Sesquiterpenes; Stereoisomerism

2002
[Chemical constituents in volatile oil from fruits of Alpinia oxyphylla Miq].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001, Volume: 26, Issue:4

    Topics: 4-Butyrolactone; Alpinia; Cymenes; Fruit; Monoterpenes; Oils, Volatile; Plant Extracts; Plants, Medicinal; Sesquiterpenes; Terpenes

2001
STRUCTURE OF MOKKO LACTONE AND DEHYDROCOSTUS LACTONE.
    Chemical & pharmaceutical bulletin, 1964, Volume: 12

    Topics: 4-Butyrolactone; Chemistry, Pharmaceutical; Lactones; Research; Sesquiterpenes

1964
A general approach toward bakkanes: short synthesis of (+/-)-bakkenolide-a (fukinanolide).
    Organic letters, 2004, Sep-16, Volume: 6, Issue:19

    Topics: 4-Butyrolactone; Catalysis; Molecular Structure; Petasites; Sesquiterpenes; Stereoisomerism

2004
In vitro cytotoxicity of Mokko lactone in human leukemia HL-60 cells: induction of apoptotic cell death by mitochondrial membrane potential collapse.
    Immunopharmacology and immunotoxicology, 2004, Volume: 26, Issue:3

    Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; DNA Fragmentation; HL-60 Cells; Humans; Intracellular Membranes; Korea; Lactones; Membrane Potentials; Mitochondria; Plant Roots; Saussurea; Sesquiterpenes

2004
Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (+/-)-biatractylolide and (+/-)-biepiasterolide.
    The Journal of organic chemistry, 2004, Dec-24, Volume: 69, Issue:26

    Topics: 4-Butyrolactone; Dimerization; Furans; Models, Molecular; Molecular Mimicry; Molecular Structure; Sesquiterpenes; Spectrum Analysis; X-Ray Diffraction

2004
Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata.
    Planta medica, 2005, Volume: 71, Issue:5

    Topics: 4-Butyrolactone; Anti-HIV Agents; HIV-1; Humans; Inhibitory Concentration 50; Litsea; Phytotherapy; Plant Extracts; Sesquiterpenes

2005
New peanut (Arachis hypogaea) phytoalexin with prenylated benzenoid and but-2-enolide moieties.
    Journal of agricultural and food chemistry, 2006, Mar-22, Volume: 54, Issue:6

    Topics: 4-Butyrolactone; Arachis; Benzene; Phytoalexins; Plant Extracts; Protein Prenylation; Seeds; Sesquiterpenes; Stilbenes; Terpenes

2006
Core structure of eremophilanes and bakkanes through niobium catalyzed Diels-Alder reaction: synthesis of (+/-)-bakkenolide A.
    The Journal of organic chemistry, 2006, Dec-22, Volume: 71, Issue:26

    Topics: 4-Butyrolactone; Catalysis; Molecular Structure; Naphthalenes; Niobium; Polycyclic Sesquiterpenes; Sesquiterpenes; Stereoisomerism

2006
[Terpenoid compounds isolated from Ligularia sagitta].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:23

    Topics: 4-Butyrolactone; Asteraceae; Oleanolic Acid; Plant Roots; Plants, Medicinal; Rhizome; Sesquiterpenes; Terpenes

2006
The alpha-methylene-gamma-butyrolactone moiety in dehydrocostus lactone is responsible for cytoprotective heme oxygenase-1 expression through activation of the nuclear factor E2-related factor 2 in HepG2 cells.
    European journal of pharmacology, 2007, Jun-22, Volume: 565, Issue:1-3

    Topics: 4-Butyrolactone; Active Transport, Cell Nucleus; Antioxidants; Cell Line; Cytoprotection; Heme Oxygenase-1; Humans; Lactones; NF-E2-Related Factor 2; Response Elements; Sesquiterpenes

2007
Enantiospecific total synthesis of (-)-bakkenolide III and formal total synthesis of (-)-bakkenolides B, C, H, L, V, and X.
    Organic letters, 2007, Aug-16, Volume: 9, Issue:17

    Topics: 4-Butyrolactone; Cyclization; Cyclohexane Monoterpenes; Indans; Ketones; Monoterpenes; Sesquiterpenes; Spiro Compounds

2007
Costunolide inhibits production of tumor necrosis factor-alpha and interleukin-6 by inducing heme oxygenase-1 in RAW264.7 macrophages.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2007, Volume: 56, Issue:12

    Topics: 4-Butyrolactone; Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Nucleus; Enzyme Induction; Heme Oxygenase-1; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-E2-Related Factor 2; Plant Extracts; Protoporphyrins; Sesquiterpenes; Tumor Necrosis Factor-alpha

2007
Conversion of optically active hydrindanone to (+)-bakkenolide-A.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:10

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Cyclization; Indicators and Reagents; Magnetic Resonance Spectroscopy; Sesquiterpenes; Spironolactone; Stereoisomerism

2008
Isolation of betulinic acid, its methyl ester and guaiane sesquiterpenoids with protein tyrosine phosphatase 1B inhibitory activity from the roots of Saussurea lappa C.B.Clarke.
    Molecules (Basel, Switzerland), 2009, Jan-08, Volume: 14, Issue:1

    Topics: 4-Butyrolactone; Betulinic Acid; Enzyme Inhibitors; Humans; Lactones; Pentacyclic Triterpenes; Plant Roots; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Saussurea; Sesquiterpenes; Sesquiterpenes, Guaiane; Triterpenes

2009
Inhibition of NF-kB and metalloproteinase-9 expression and secretion by parthenolide derivatives.
    Bioorganic & medicinal chemistry letters, 2009, Apr-01, Volume: 19, Issue:7

    Topics: 4-Butyrolactone; Cell Line; Cyclobutanes; Down-Regulation; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase 9; NF-kappa B; Sesquiterpenes; Transcription, Genetic

2009
Spasmolytic and anti-inflammatory effects of constituents from Hertia cheirifolia.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:12

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Asteraceae; Carrageenan; Edema; Female; Male; Molecular Structure; Muscle, Smooth; Parasympatholytics; Phytotherapy; Plant Components, Aerial; Plant Extracts; Propylamines; Rats; Rats, Wistar; Sesquiterpenes; Stigmasterol

2009
A new sesquiterpene from the roots of Vladimiria souliei.
    Natural product communications, 2009, Volume: 4, Issue:6

    Topics: 4-Butyrolactone; Molecular Structure; Plant Roots; Plants, Medicinal; Sesquiterpenes; Sitosterols

2009
[Studies on chemical constituents of rhizome of Buddleia davidii].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2009, Volume: 32, Issue:4

    Topics: 4-Butyrolactone; Benzodioxoles; Buddleja; Chromatography, High Pressure Liquid; Dioxoles; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Roots; Plants, Medicinal; Sesquiterpenes; Steroids

2009
Chemical constituents of the bark of Machilus wangchiana and their biological activities.
    Journal of natural products, 2009, Volume: 72, Issue:12

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Drugs, Chinese Herbal; Female; Flavonoids; Ginkgolides; Glucuronidase; Humans; Lactones; Lauraceae; Lignans; Molecular Structure; Neutrophils; Plant Bark; Rats; Sesquiterpenes; Stereoisomerism

2009
A ring contraction strategy toward a diastereoselective total synthesis of (+)-bakkenolide A.
    The Journal of organic chemistry, 2010, May-07, Volume: 75, Issue:9

    Topics: 4-Butyrolactone; Antineoplastic Agents; Hydrogenation; Insecticides; Ketones; Molecular Conformation; Molecular Structure; Senecio; Sesquiterpenes; Spiro Compounds; Stereoisomerism; Thallium

2010
Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA Fragmentation; Humans; Male; Mice; Neoplasm Transplantation; NF-kappa B; Nitriles; Oxides; Prostatic Neoplasms; Sesquiterpenes; Spiro Compounds; Structure-Activity Relationship

2011
Selectivity in reduction of natural furanoheliangolides with Stryker's reagent.
    Organic & biomolecular chemistry, 2011, Sep-07, Volume: 9, Issue:17

    Topics: 4-Butyrolactone; Biomimetics; Bridged-Ring Compounds; Furans; Lactones; Oxidation-Reduction; Sesquiterpenes; Sesterterpenes

2011
The antidepressant-like effect of Hedyosmum brasiliense and its sesquiterpene lactone, podoandin in mice: evidence for the involvement of adrenergic, dopaminergic and serotonergic systems.
    European journal of pharmacology, 2012, Jan-15, Volume: 674, Issue:2-3

    Topics: 4-Butyrolactone; Analgesics, Opioid; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Cycloheptanes; Dopamine; Drug Interactions; Epinephrine; Ferns; Fluoxetine; Lactones; Locomotion; Male; Mice; Neurotransmitter Agents; Nitric Oxide; Norepinephrine; Plant Extracts; Serotonin; Sesquiterpenes; Swimming

2012
Identification and quantification of the major volatile constituents in antidepressant active fraction of xiaoyaosan by gas chromatography-mass spectrometry.
    Journal of ethnopharmacology, 2012, May-07, Volume: 141, Issue:1

    Topics: 4-Butyrolactone; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lactones; Male; Mice; Mice, Inbred ICR; Molecular Structure; Motor Activity; Palmitic Acid; Phytotherapy; Plants, Medicinal; Sesquiterpenes; Volatilization

2012
Enantioselective and collective syntheses of xanthanolides involving a controllable dyotropic rearrangement of cis-β-lactones.
    Angewandte Chemie (International ed. in English), 2012, Jul-09, Volume: 51, Issue:28

    Topics: 4-Butyrolactone; Biological Products; Lactones; Molecular Structure; Sesquiterpenes; Stereoisomerism; Xanthium

2012
[Chemical constituents of Dolomiaea souliei].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:9

    Topics: 4-Butyrolactone; Asteraceae; Betulinic Acid; Emodin; Lactones; Pentacyclic Triterpenes; Sesquiterpenes; Triterpenes; Ursolic Acid

2012
Antimycobacterials from lovage root (Ligusticum officinale Koch).
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:7

    Topics: 4-Butyrolactone; Animals; Antibiotics, Antitubercular; Cytotoxins; Diynes; Fatty Alcohols; Furocoumarins; Ligusticum; Macrophages; Mice; Mycobacterium bovis; Mycobacterium smegmatis; Mycobacterium tuberculosis; Phytotherapy; Plant Extracts; Plant Roots; Sesquiterpenes

2013
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ.
    Journal of medicinal chemistry, 2012, Oct-11, Volume: 55, Issue:19

    Topics: 4-Butyrolactone; Animals; Aquatic Organisms; Binding Sites; Furans; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Dynamics Simulation; Polyketides; Porifera; PPAR gamma; Protein Structure, Tertiary; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Transcriptional Activation

2012
Semisynthesis of N-acyl homoserinelactone derivatives and the antifeedant activity against Mythimna separata.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2013, Volume: 48, Issue:8

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Animals; Benzamides; Insecticides; Magnetic Resonance Spectroscopy; Molecular Structure; Moths; Picrotoxin; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Umbelliferones

2013
Simultaneous determination of bioactive components in essential oil of Xiang-Fu-Si-Wu Formula in Beagle dog plasma by UPLC-MS/MS and its application to pharmacokinetics.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jun-15, Volume: 929

    Topics: 4-Butyrolactone; Animals; Chromatography, High Pressure Liquid; Dogs; Female; Lactones; Reproducibility of Results; Sesquiterpenes; Tandem Mass Spectrometry

2013
Asymmetric synthesis of both enantiomers of arteludovicinolide A.
    Organic letters, 2013, Jul-05, Volume: 15, Issue:13

    Topics: 4-Butyrolactone; Molecular Structure; Sesquiterpenes; Stereoisomerism

2013
Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activities.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: 4-Butyrolactone; Amination; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Pancreatic Neoplasms; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship

2013
A simultaneous determination of principal compounds in tokishakuyakusan by high-performance liquid chromatography with diode array detector.
    Journal of chromatographic science, 2015, Volume: 53, Issue:2

    Topics: 4-Butyrolactone; Cholestenones; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Lactones; Limit of Detection; Linear Models; Monoterpenes; Reproducibility of Results; Sesquiterpenes

2015
Volatile profile of cashew apple juice fibers from different production steps.
    Molecules (Basel, Switzerland), 2015, May-27, Volume: 20, Issue:6

    Topics: 4-Butyrolactone; Aldehydes; Alkenes; Anacardium; Beverages; Caprylates; Fruit; Odorants; Polycyclic Sesquiterpenes; Pressure; Principal Component Analysis; Sesquiterpenes; Solid Phase Microextraction; Terpenes

2015
Structure and absolute configuration of hydroxy-bis-dihydrofarinosin from Encelia farinosa.
    Magnetic resonance in chemistry : MRC, 2017, Volume: 55, Issue:6

    Topics: 4-Butyrolactone; Asteraceae; Circular Dichroism; Crystallography, X-Ray; Heterocyclic Compounds, 3-Ring; Magnetic Resonance Spectroscopy; Molecular Structure; Sesquiterpenes; Stereoisomerism

2017
A LC-MS validated method for quantification of rosmarinic acid and sesquiterpene lactones in Hedyosmum brasiliense.
    Journal of chromatographic science, 2018, Oct-01, Volume: 56, Issue:9

    Topics: 4-Butyrolactone; Chromatography, Liquid; Cinnamates; Cycloheptanes; Depsides; Linear Models; Plant Extracts; Reproducibility of Results; Rosmarinic Acid; Sensitivity and Specificity; Sesquiterpenes; Tandem Mass Spectrometry; Tracheophyta

2018
Bioactive secondary metabolites from the marine-associated fungus Aspergillus terreus.
    Bioorganic chemistry, 2018, Volume: 80

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anti-Inflammatory Agents; Aspergillus; Bacteria; Biological Products; Glycoside Hydrolase Inhibitors; Mice; Molecular Docking Simulation; Nitric Oxide; RAW 264.7 Cells; Saccharomyces cerevisiae; Secondary Metabolism; Sesquiterpenes

2018
Metabolites from the Paracel Islands Soft Coral
    Marine drugs, 2018, Dec-19, Volume: 16, Issue:12

    Topics: 4-Butyrolactone; Animals; Anthozoa; Cell Line, Tumor; Cyclopentanes; Cytotoxins; HCT116 Cells; HeLa Cells; Humans; Molecular Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Sesquiterpenes

2018
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth.
    The Journal of biological chemistry, 2020, 03-13, Volume: 295, Issue:11

    Topics: 4-Butyrolactone; Apoptosis; beta Catenin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Proteolysis; Sesquiterpenes; Ubiquitin-Specific Peptidase 7; Ubiquitination; Wnt Signaling Pathway

2020
Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.
    Chemical biology & drug design, 2020, Volume: 96, Issue:2

    Topics: 4-Butyrolactone; Amines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Female; Humans; Molecular Targeted Therapy; NF-kappa B; Ovarian Neoplasms; Piperazines; Piperidines; Prodrugs; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Sesquiterpenes; Signal Transduction; Structure-Activity Relationship

2020
Mokko Lactone Attenuates Doxorubicin-Induced Hepatotoxicity in Rats: Emphasis on Sirt-1/FOXO1/NF-κB Axis.
    Nutrients, 2021, Nov-19, Volume: 13, Issue:11

    Topics: 4-Butyrolactone; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Doxorubicin; Glutathione; Liver; Malondialdehyde; Nerve Tissue Proteins; NF-kappa B; Rats; Sesquiterpenes; Signal Transduction; Sirtuin 1; Superoxide Dismutase

2021
Mokko Lactone Alleviates Doxorubicin-Induced Cardiotoxicity in Rats via Antioxidant, Anti-Inflammatory, and Antiapoptotic Activities.
    Nutrients, 2022, Feb-09, Volume: 14, Issue:4

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cardiotoxicity; Doxorubicin; Myocardium; Oxidative Stress; Rats; Sesquiterpenes

2022