Page last updated: 2024-08-18

4-butyrolactone and sarcophine

4-butyrolactone has been researched along with sarcophine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's0 (0.00)18.2507
2000's9 (50.00)29.6817
2010's7 (38.89)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Erman, A; Neéman, I1
Fahmy, H; Katsuyama, I; Khalifa, SI; Kilada, RW; Konoshima, T; Takasaki, M; Tokuda, H; Zjawiony, JK1
Fahmy, H; Fronczek, FR; Khalifa, S; Zjawiony, JK1
Avery, MA; Desai, P; El Sayed, KA; Sawant, SS; Sylvester, PW; Youssef, DT1
Kusumi, T; Matsuoka, K; Munakata, T; Nii, K; Ooi, T; Tagami, K1
El Sayed, KA; Ferniz, M; Marchetti, D; Reiland, J; Sawant, SS; Youssef, DT1
Arant, M; El Sayed, K; Mayer, A; Sawant, S; Sylvester, P; Wali, V; Youssef, D1
Dwivedi, C; Fahmy, H; Khalifa, S; Kundoor, V; Zeman, D; Zhang, X1
Abou El-Ela, SH; Bilasy, Sel-S; Khalifa, SI; Saleh, SM1
Bommareddy, A; Chen, W; Dwivedi, C; Fahmy, H; Hildreth, MB; Kaushik, RS; Khalifa, S; Zeman, D; Zhang, X1
El Sayed, KA; Hassan, HM; Hifnawy, MS; Mohammed, R; Sallam, AA; Youssef, DT1
Ahmed, SA; Fahmy, H; Khalifa, S; Kuppast, B; Szymanski, PT1
Ahmed, SA; Fahmy, H; Khalifa, SI; Radwan, MM; Szymanski, PT1
Alhammady, MA; El-Beih, AA; Elkhateeb, A; Gamal-Eldeen, AM; Hegazy, ME; Ohta, S; Paré, PW1
Chen, K; Conti, PS; Li, G; Wang, J; Wang, X; Zong, S1
Elshamy, AI; Hamed, AR; Hegazy, MF; Ibrahim, MAA; Mohamed, TA; Ohta, S; Paré, PW1
Abdelwahab, AB; Ghani, MA; Hamed, A; Issa, MY; Shaaban, M1
Breitinger, HG; Breitinger, U; Noureldin, N; Raafat, KM; Saleh, HA; Temraz, TA1

Other Studies

18 other study(ies) available for 4-butyrolactone and sarcophine

ArticleYear
Inhibition of phosphofructokinase by the toxic cembranolide sarcophine isolated from the soft-bodied coral Sarcophyton glaucum.
    Toxicon : official journal of the International Society on Toxinology, 1977, Volume: 15, Issue:3

    Topics: 4-Butyrolactone; Amino Acids; Animals; Chemical Phenomena; Chemistry; Cnidaria; Hydrogen-Ion Concentration; Kinetics; Lactones; Marine Toxins; Phosphofructokinase-1; Proteins; Sulfhydryl Compounds

1977
Semisynthesis of new sarcophine derivatives with chemopreventive activity.
    Journal of natural products, 2002, Volume: 65, Issue:12

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anticarcinogenic Agents; Antigens, Viral; Chemoprevention; Dose-Response Relationship, Drug; Egypt; Hydroxylation; Indian Ocean; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Selenium Compounds; Selenium Oxides; Stereoisomerism; Structure-Activity Relationship

2002
A semi-synthetic analog of the cembranoid sarcophine.
    Acta crystallographica. Section C, Crystal structure communications, 2003, Volume: 59, Issue:Pt 2

    Topics: 4-Butyrolactone; Animals; Anthozoa; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular

2003
Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine.
    Journal of natural products, 2004, Volume: 67, Issue:12

    Topics: 4-Butyrolactone; Animals; Anthozoa; Antineoplastic Agents; Crystallography, X-Ray; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hydrocarbons, Brominated; Indian Ocean; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Tumor Cells, Cultured

2004
Unusual transannular cyclization products of sarcophytoxide, a 14-membered marine cembranoid: anomalous stereochemistry of epoxide-ketone rearrangement.
    Organic letters, 2006, Jul-06, Volume: 8, Issue:14

    Topics: 4-Butyrolactone; Animals; Anthozoa; Crystallography, X-Ray; Cyclization; Diterpenes; Epoxy Compounds; Humans; Ketones; Marine Biology; Molecular Conformation; Molecular Structure; Stereoisomerism

2006
Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine.
    Journal of natural products, 2006, Volume: 69, Issue:7

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anticarcinogenic Agents; Diterpenes; Drug Screening Assays, Antitumor; Marine Biology; Melanoma; Mice; Molecular Structure; Tumor Cells, Cultured; Wound Healing

2006
Anticancer and anti-inflammatory sulfur-containing semisynthetic derivatives of sarcophine.
    Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:8

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Mass Spectrometry; Mice; Molecular Structure; Rats; Sulfur

2006
Chemopreventive effects of sarcophine-diol on skin tumor development in CD-1 mice.
    Cancer letters, 2007, Aug-08, Volume: 253, Issue:1

    Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Caspase 3; Caspase 8; Caspase 9; Cell Proliferation; Cyclooxygenase 2; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
HPLC method for the quantitative determination of sarcophine, a source of cembranoids with cancer chemopreventive activity.
    Journal of pharmaceutical and biomedical analysis, 2008, Mar-13, Volume: 46, Issue:4

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anticarcinogenic Agents; Chromatography, High Pressure Liquid

2008
Chemopreventive effects of sarcophine-diol on ultraviolet B-induced skin tumor development in SKH-1 hairless mice.
    Marine drugs, 2009, Apr-30, Volume: 7, Issue:2

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Apoptosis; Body Weight; Carcinoma, Squamous Cell; Caspase 3; Caspase 8; DNA Fragmentation; Female; Gene Expression Regulation, Enzymologic; Mice; Mice, Hairless; Models, Animal; Neoplasms, Radiation-Induced; Skin Neoplasms; Ultraviolet Rays

2009
Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors.
    Bioorganic & medicinal chemistry, 2011, Aug-15, Volume: 19, Issue:16

    Topics: 4-Butyrolactone; Animals; Anthozoa; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Migration Assays; Cell Migration Inhibition; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Female; Humans; Indian Ocean; Male; Prostatic Neoplasms; Structure-Activity Relationship

2011
Sarcophine-diol, a skin cancer chemopreventive agent, inhibits proliferation and stimulates apoptosis in mouse melanoma B₁₆F₁₀ cell line.
    Marine drugs, 2012, Volume: 10, Issue:1

    Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 4; Diterpenes; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Melanoma, Experimental; Mice; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Skin Neoplasms; STAT3 Transcription Factor

2012
Evaluation of the anti-melanoma activities of sarcophine, (+)-7alpha,8beta-dihydroxydeepoxysarcophine and sarcophytolide from the Red Sea soft coral Sarcophyton glaucum.
    Natural product communications, 2014, Volume: 9, Issue:2

    Topics: 4-Butyrolactone; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Diterpenes; Melanoma, Experimental; Mice

2014
New terpenes from the Egyptian soft coral Sarcophyton ehrenbergi.
    Marine drugs, 2014, Apr-02, Volume: 12, Issue:4

    Topics: 4-Butyrolactone; Adenocarcinoma; Animals; Anthozoa; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Egypt; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; MCF-7 Cells; Terpenes

2014
MicroPET imaging of CD13 expression using a (64)Cu-labeled dimeric NGR peptide based on sarcophagine cage.
    Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11

    Topics: 4-Butyrolactone; Animals; Catalysis; CD13 Antigens; Cell Line, Tumor; Chromatography, High Pressure Liquid; Click Chemistry; Copper Radioisotopes; Dimerization; Female; Gene Expression Regulation; Humans; Liver; MCF-7 Cells; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Positron-Emission Tomography; Tissue Distribution

2014
Cembrene Diterpenoids with Ether Linkages from Sarcophyton ehrenbergi: An Anti-Proliferation and Molecular-Docking Assessment.
    Marine drugs, 2017, Jun-21, Volume: 15, Issue:6

    Topics: 4-Butyrolactone; A549 Cells; Animals; Anthozoa; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Diterpenes; Ether; Hep G2 Cells; Humans; Indian Ocean; Magnetic Resonance Spectroscopy; Molecular Docking Simulation

2017
New pyranosyl cembranoid diterpenes from Sarcophyton trocheliophorum.
    Natural product research, 2019, Volume: 33, Issue:1

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anti-Infective Agents; Diterpenes; Epothilones; Indian Ocean; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Molecular Structure; Paclitaxel; Tubulin

2019
Sarcophine and (7S, 8R)-dihydroxydeepoxysarcophine from the Red Sea soft coral Sarcophyton glaucum as in vitro and in vivo modulators of glycine receptors.
    Neurotoxicology, 2020, Volume: 80

    Topics: 4-Butyrolactone; Animals; Anthozoa; Binding Sites; Binding, Competitive; Brain; Disease Models, Animal; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Male; Mice; Protein Binding; Receptors, Glycine; Seizures; Strychnine

2020