Compounds > 4-butyrolactone
Page last updated: 2024-08-18

4-butyrolactone and podophyllotoxin

4-butyrolactone has been researched along with podophyllotoxin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Kupchan, SM; Rebhum, LI; Wang, RW1
Gupta, RS1
Tomioka, K1
Sackett, DL1
Bos, R; Koulman, A; Medarde, M; Pras, N; Quax, WJ1
Burnett, JC; Day, BW; Gussio, R; Hamel, E; Hermone, AR; McGrath, C; Nguyen, TL; Wipf, P; Zaharevitz, DW1
Cafici, L; Canonico, PL; Galli, U; Genazzani, AA; Imperio, D; Pagliai, F; Pirali, T; Sorba, G; Tron, GC1
Avila, J; Cerda-García-Rojas, CM; García-Mauriño, S; Gómez-Hurtado, MA; Hernández-Hernández, JD; Joseph-Nathan, P; Manríquez-Torres, JJ; Motilva, V; Román-Marín, LU; Talero, E; Torres-Valencia, JM; Valdez-Calderón, A; Velázquez-Jiménez, R1
Decembrino, D; Girhard, M; Jach, G; Ricklefs, E; Schullehner, K; Urlacher, VB; Wohlgemuth, S1
Anoop, A; Garai, S; Hajra, S; Roy, S; Sen, B1

Reviews

2 review(s) available for 4-butyrolactone and podophyllotoxin

ArticleYear
[Asymmetric total synthesis of some biologically active natural products].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1984, Volume: 104, Issue:10

    Topics: 4-Butyrolactone; Alkaloids; Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry; Dioxoles; Furans; Galantamine; Lactones; Lignans; Methods; Molecular Conformation; Optical Rotation; Podophyllotoxin

1984
Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin.
    Pharmacology & therapeutics, 1993, Volume: 59, Issue:2

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Binding Sites; Cell Division; Lignans; Podophyllotoxin; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin

1993

Other Studies

8 other study(ies) available for 4-butyrolactone and podophyllotoxin

ArticleYear
Antimitotic and antitubulin activity of the tumor inhibitor steganacin.
    Cancer research, 1977, Volume: 37, Issue:9

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Binding, Competitive; Cell Division; Colchicine; Cycloparaffins; Female; Glycoproteins; Lactones; Lignans; Microtubules; Mitosis; Ovum; Podophyllotoxin; Sea Urchins; Tubulin; Tubulin Modulators; Ultracentrifugation

1977
Species-specific differences in toxicity of antimitotic agents toward cultured mammalian cells.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1

    Topics: 4-Butyrolactone; Animals; Benzimidazoles; Biological Transport; Cells, Cultured; Colchicine; Cricetinae; Cricetulus; Griseofulvin; HeLa Cells; Humans; Lignans; Maytansine; Mice; Mitosis; Nocodazole; Podophyllotoxin; Species Specificity; Vinblastine

1985
A fast and simple GC MS method for lignan profiling in Anthriscus sylvestris and biosynthetically related Plant species.
    Planta medica, 2001, Volume: 67, Issue:9

    Topics: 4-Butyrolactone; Apiaceae; Dioxoles; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Lignans; Plant Extracts; Podophyllotoxin

2001
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19

    Topics: 2-Methoxyestradiol; 4-Butyrolactone; Aminophenols; Binding Sites; Chalcone; Colchicine; Cyclopropanes; Estradiol; Indans; Lignans; Models, Molecular; Molecular Structure; Nocodazole; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tubulin; Tubulin Modulators

2005
Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry.
    Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21

    Topics: 4-Butyrolactone; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Humans; Lactones; Lignans; Molecular Conformation; Podophyllotoxin; Ruthenium; Triazoles; Tubulin

2007
Absolute configuration of podophyllotoxin related lignans from Bursera fagaroides using vibrational circular dichroism.
    Phytochemistry, 2011, Volume: 72, Issue:17

    Topics: 4-Butyrolactone; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Benzofurans; Bursera; Cell Line, Tumor; Circular Dichroism; Colonic Neoplasms; Dioxoles; Drugs, Chinese Herbal; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Phytotherapy; Plant Extracts; Plant Exudates; Podophyllotoxin

2011
Assembly of Plant Enzymes in
    ACS synthetic biology, 2020, 11-20, Volume: 9, Issue:11

    Topics: 4-Butyrolactone; Berberidaceae; Biotransformation; Cytochrome P-450 Enzyme System; Escherichia coli; Forsythia; Furans; Lignans; NADP; Oxidation-Reduction; Podophyllotoxin; Podophyllum peltatum

2020
Stereochemistry of the Benzylidene γ-Butyrolactone Dictates the Reductive Heck Cyclization Mode in the Asymmetric Synthesis of Aryltetralin Lignans: A Detailed Experimental and Theoretical Study.
    The Journal of organic chemistry, 2022, 03-18, Volume: 87, Issue:6

    Topics: 4-Butyrolactone; Cyclization; Lignans; Models, Theoretical; Molecular Structure; Podophyllotoxin

2022