Compounds > 4-butyrolactone
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4-butyrolactone and plasminogen activator inhibitor 2

4-butyrolactone has been researched along with plasminogen activator inhibitor 2 in 102 studies

Research

Studies (102)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (11.76)18.2507
2000's42 (41.18)29.6817
2010's41 (40.20)24.3611
2020's7 (6.86)2.80

Authors

AuthorsStudies
Greenberg, EP; Iglewski, BH; Passador, L; Pearson, JP1
Bycroft, B; Chhabra, SR; Christiansen, G; Eberl, L; Givskov, M; Molin, S; Sternberg, C; Stewart, GS; Williams, P; Winson, MK1
Iglewski, BH; Pearson, JP; Pesci, EC; Seed, PC1
Beyeler, M; Foglino, M; Haas, D; Latifi, A; Lazdunski, A; Reimmann, C; Winteler, H1
Chhabra, SR; Durant, EL; Fish, L; Karlyshev, AV; Macintyre, S; Stewart, GS; Swift, S; Williams, P; Winson, MK1
Bycroft, BW; Camara, M; Chhabra, SR; Hardie, KR; Jiang, Y; Lazdunski, A; Salmond, GP; Stewart, GS; Williams, P1
Fukushima, J; Kawamoto, S; Okuda, K; Tanaka, K; You, Z1
Anthoni, U; Christophersen, C; Eberl, L; Givskov, M; Lindum, PW; Molin, S1
Iglewski, BH; Pearson, JP; Van Delden, C1
Hoang, TT; Schweizer, HP1
Fish, L; Kirke, DF; Lynch, MJ; Stewart, GS; Swift, S; Tomás, JM; Williams, P1
Burnett, S; Elkins, JG; Fredericks, J; Hassett, DJ; Huang, CT; Iglewski, BH; Ma, JF; McDermott, TR; McFeters, G; Ochsner, UA; Passador, L; Stewart, PS; West, SE1
Holden, I; Swift, I; Williams, I1
Iglewski, BH; McKnight, SL; Pesci, EC1
Haas, D; Pessi, G1
Harris, SG; Iglewski, B; Phipps, R; Smith, RS1
Blanc, D; Favre-Bonté, S; Pache, JC; Pechère, JC; Robert, J; van Delden, C1
Dodd, CE; Keevil, CW; Kirke, DF; Lynch, MJ; Swift, S; Williams, P1
Juárez, K; Medina, G; Soberón-Chávez, G1
Brooks, AI; Bushnell, D; Iglewski, BH; Passador, L; Wagner, VE1
Dénervaud, V; Haas, D; Heurlier, K; Pessi, G; Reimmann, C1
Bu, Y; Smith, KM; Suga, H1
Favre-Bonté, S; Köhler, T; Van Delden, C1
Cámara, M; Chhabra, SR; Diggle, SP; Williams, P; Winzer, K; Worrall, KE1
Iglewski, BH; Lamb, JR; Montminy, T; Patel, H; Wagner, VE1
Chun, CK; Greenberg, EP; Ozer, EA; Welsh, MJ; Zabner, J1
Hastings, JW1
Maseda, H; Nakae, T; Nomura, N; Saito, K; Sawada, I; Uchiyama, H1
Carty, NL; Griswold, JA; Hamood, AN; Patterson, EK; Rumbaugh, KP; Williams, SC1
Eberl, L; Heesemann, J; Hogardt, M; Roeder, M; Schreff, AM1
Maseda, H; Nakae, T; Nomura, N; Sawada, I; Uchiyama, H1
Dutton, JM; Glansdorp, FG; Lee, JK; Salmond, GP; Spring, DR; Thomas, GL; Welch, M1
Kirke, DF; Lynch, MJ; Swift, S; Williams, P1
Dong, YH; Greenberg, EP; Soo, HM; Zhang, LH; Zhang, XF1
Aridoğan, B; Boşgelmez-Tinaz, G; Eroğlu, F; Kaya, S; Ulusoy, S1
Cámara, M; Chhabra, SR; Cockayne, A; Hill, P; Middleton, B; Muharram, SH; O'Shea, P; Qazi, S; Williams, P1
Debevere, J; Demolder, V; Medina-Martínez, MS; Uyttendaele, M2
Huang, XQ; Tang, XY; Xu, YQ; Yan, A; Zhang, XH1
Dong, D; Huang, X; Liu, H; Xu, Y; Yan, A; Zhang, D; Zhang, X1
Marsaioli, AJ; Paccola-Meirelles, LD; Pomini, AM1
Ikeda, T; Ishida, T; Kato, J; Kuroda, A; Ohtake, H; Takiguchi, N1
Basseres, E; Kader, A; Möllby, R; Rahman, M; Römling, U; Simm, R1
Arnold, FH; Hauer, B; Hawkins, AC; Leadbetter, JR; Stuermer, R1
Boşgelmez-Tinaz, G; Ulusoy, S1
Banin, E; Gilmour, C; Greenberg, EP; Patriquin, GM; Poole, K; Tuchman, R1
Raychaudhuri, A; Tipton, PA; Tullock, A1
Bruhn, JB; Dalsgaard, I; Givskov, M; Gram, L; Kastbjerg, VG; Rasch, M1
Conibear, TC; Thuruthyil, SJ; Willcox, MD; Zhu, H1
Barash, I; Chalupowicz, L; Itkin, M; Manulis-Sasson, S; Sacher, A; Sessa, G1
Atamova, EE; Khmel', IA; Lipasova, VA; Tarasova, NN; Veselova, MA1
Gotoh, N; Horikawa, M; Ishiguro, M; Ishii, Y; Kimura, S; Miyairi, S; Tateda, K; Yamaguchi, K1
Hoang, TT; Kang, Y; Lunin, VV; Savchenko, A; Schurr, MJ; Skarina, T1
Huang, X; Jiang, H; Li, S; Lu, J; Xu, Y; Zhang, M1
Baucher, M; Diallo, B; El Jaziri, M; Kiendrebeogo, M; Mol, A; Rajaonson, S; Vandeputte, OM1
Bjarnsholt, T; Claussen, A; Ferkinghoff-Borg, J; Garde, C; Givskov, M; Hentzer, M; Jakobsen, TH; Sams, T; Sneppen, K1
Collet, A; Cosette, P; Jouenne, T; Junter, GA; Nigaud, Y; Song, PC; Vaudry, D; Vaudry, H1
Barrett, DA; Cámara, M; Cifelli, PM; Erskine, P; Givskov, M; Holland, ED; Knox, A; Lewis, S; Ortori, CA; Righetti, K; Smyth, AR; Williams, P1
Baziard, G; Berge, M; El Hage, S; Furiga, A; Khalilzadeh, P; Lajoie, B; Roques, C1
Ng, FS; Seah, SY; Wright, DM1
Baucher, M; Diallo, B; Duez, P; El Jaziri, M; Kiendrebeogo, M; Mol, A; Rajaonson, S; Rasamiravaka, T; Stévigny, C; Vandeputte, OM1
Bian, Z; Jia, Z; Song, S; Xu, J; Zhang, Z1
Aduse-Opoku, J; Curtis, MA; Hashim, A; Rangarajan, M; Rose, RS; Waite, RD1
Baldansuren, A; Chow, JY; Dikanov, SA; Gan, YH; Robinson, RC; Xue, B; Yap, LL; Yew, WS1
Ikeda, T; Ito, S; Morohoshi, T; Saito, Y; Someya, N; Suto, T; Wang, WZ1
Barash, I; Chalupowicz, L; Manulis-Sasson, S; Panijel, M; Sessa, G1
Boon, C; Chen, S; Deng, Y; Lim, A; Zhang, LH1
Bezirtzoglou, E; Bleotu, C; Chifiriuc, MC; Holban, AM; Lazar, V1
Martínez, JL1
Bazire, A; Dufour, A1
Adrian, TG; Chan, KG; Mohamad, NI; Tan, PW; Tan, WS; Yin, WF; Yunos, NY1
Bandekar, JR; Nagar, V; Sinha, V1
Ding, Y; Feng, H; Huang, W; Shen, D; Wang, M1
Gotoh, N; Ishii, K; Kamimatsuno, R; Kanno, E; Kawakami, K; Maruyama, R; Miyairi, S; Miyasaka, T; Suzuki, A; Tachi, M; Takagi, N; Tanno, H1
Corral-Lugo, A; Daddaoua, A; Espinosa-Urgel, M; Krell, T; Ortega, A1
Abu Kasim, NH; Chan, KG; Goh, SY; Khan, SA; Tee, KK; Yin, WF1
Jatt, AN; Zeng, M; Zhang, C; Zhu, S1
Liu, J; Luo, Y; Ni, Y; Qian, X; Tao, S; Zhao, R1
Bai, F; Cui, F; Li, J; Li, T; Zhao, G1
Bai, D; Chen, L; Duan, K; Guo, Q; Jin, S; Liu, Y; Wu, Q; Wu, Y1
Evans, GB; Fineran, PC; Jackson, SA; Patterson, AG; Przybilski, R; Salmond, GPC; Staals, RHJ; Taylor, C1
Bahari, S; Haghi, F; Mirshahabi, H; Roudashti, S; Zeighami, H1
González-Valdez, A; Morales, E; Servín-González, L; Soberón-Chávez, G1
Carlot, S; Chatelain, P; Dumont, JE; Hassid, S; Tarabichi, M; Veithen, A; Verbeurgt, C1
D'Angelo, F; Kuruma, Y; Leoni, L; Messina, M; Rampioni, G; Stano, P; Tofani, D; Zennaro, A1
Alayande, AB; Aung, MM; Kim, IS1
Bae, H; Chi, YT; Choi, GW; Choi, HJ; Jang, MC; Jo, AR; Ku, YG; Lee, DJ; Nam, J; Sung, HY1
DeLateur, NA; Goldenfeld, N; Karig, D; Lu, T; Martini, KM; Weiss, R1
Bagchi, A; Chowdhury, N1
Agarwal, V; Kalia, M; Sharma, D; Singh, PK; Singh, SK; Yadav, VK1
Blackwell, HE; Boursier, ME; Brown, EC; Combs, JB; Heitman, KM; Koenig, LC; Moore, JD; Nagarajan, R; Shepardson-Fungairino, SP; Shin, D1
Chan, KG; Hong, KW; How, KY; Kher, HL; Krishnan, T; Lee, LH; Letchumanan, V; Tee, KK; Yin, WF1
Bakirdere, S; Caglak, A; Chormey, DS; Engin, GO; Saral, M; Sari Erkan, H; Turan, NB1
Lan, X; Li, H; Li, W; Liu, K; Zhao, M1
Feng, L; Li, J; Liu, X; Tang, R; Zhu, J1
Addis, V; Dar, D; Fitzgerald, D; Gottesman, S; Greenberg, EP; Sorek, R; Thomason, MK; Voichek, M1
Badal, D; Jayarani, AV; Kollaran, MA; Kumar, A; Singh, V1
Grygier, A; Majcher, M; Myszka, K; Sobieszczańska, N; Szwengiel, A; Wolko, Ł1
Geng, YF; Mei, J; Sun, YJ; Tao, SN; Yang, C; Zhang, XC; Zhang, Y; Zhao, BT1
Golmohammadi, R; Mirnejad, R; Moosazadeh Moghaddam, M; Shahbandeh, M1
Duan, L; Gao, H; Wu, Z; Ye, J; Yu, R; Zhao, R1
Cheng, J; He, Y; Liu, M; Lu, Z; Su, X; Xu, J1

Trials

1 trial(s) available for 4-butyrolactone and plasminogen activator inhibitor 2

ArticleYear
Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial.
    Pediatric pulmonology, 2010, Volume: 45, Issue:4

    Topics: 4-Butyrolactone; Adolescent; Adult; Child; Cystic Fibrosis; Female; Garlic; Homoserine; Humans; Male; Middle Aged; Phytotherapy; Pilot Projects; Plant Oils; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Respiratory Function Tests; Sputum; Treatment Outcome; Young Adult

2010

Other Studies

101 other study(ies) available for 4-butyrolactone and plasminogen activator inhibitor 2

ArticleYear
A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Feb-28, Volume: 92, Issue:5

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Pancreatic Elastase; Promoter Regions, Genetic; Pseudomonas aeruginosa; Trans-Activators

1995
Involvement of N-acyl-L-hormoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens.
    Molecular microbiology, 1996, Volume: 20, Issue:1

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Chromatography, High Pressure Liquid; Culture Media; Genes, Bacterial; Molecular Sequence Data; Movement; Phenotype; Serratia; Signal Transduction

1996
Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa.
    Journal of bacteriology, 1997, Volume: 179, Issue:10

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Genes, Bacterial; Protein Processing, Post-Translational; Pseudomonas aeruginosa; Trans-Activators; Transcription, Genetic

1997
The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase.
    Molecular microbiology, 1997, Volume: 24, Issue:2

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Chromosome Mapping; Cloning, Molecular; Cyanides; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Lipase; Molecular Sequence Data; Plasmids; Pseudomonas aeruginosa; Pyocyanine; Sequence Alignment; Signal Transduction; Trans-Activators; Transcription, Genetic

1997
Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules.
    Journal of bacteriology, 1997, Volume: 179, Issue:17

    Topics: 4-Butyrolactone; Aeromonas; Aeromonas hydrophila; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Chromosome Mapping; Cloning, Molecular; DNA-Binding Proteins; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Recombinant Fusion Proteins; Repressor Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Serine Endopeptidases; Signal Transduction; Trans-Activators; Transcription Factors

1997
In vitro biosynthesis of the Pseudomonas aeruginosa quorum-sensing signal molecule N-butanoyl-L-homoserine lactone.
    Molecular microbiology, 1998, Volume: 28, Issue:1

    Topics: 4-Butyrolactone; Acetyl Coenzyme A; Bacterial Proteins; Cerulenin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Kinetics; Ligases; Mass Spectrometry; Pseudomonas aeruginosa; Recombinant Proteins; S-Adenosylmethionine; Substrate Specificity; Transcription Factors

1998
Induction of entry into the stationary growth phase in Pseudomonas aeruginosa by N-acylhomoserine lactone.
    FEMS microbiology letters, 1998, Jul-01, Volume: 164, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; Electrophoresis, Polyacrylamide Gel; Homoserine; Immunoblotting; Microscopy, Atomic Force; Polymerase Chain Reaction; Pseudomonas aeruginosa; RNA, Bacterial; RNA, Messenger; Sigma Factor; Time Factors

1998
N-Acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1.
    Journal of bacteriology, 1998, Volume: 180, Issue:23

    Topics: 4-Butyrolactone; Amino Acid Sequence; Cell Movement; Conserved Sequence; Extracellular Space; Genes, Bacterial; Lipoproteins; Molecular Sequence Data; Molecular Structure; Peptide Synthases; Peptides, Cyclic; Sequence Homology, Amino Acid; Serratia; Surface-Active Agents

1998
Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals.
    Journal of bacteriology, 1999, Volume: 181, Issue:4

    Topics: 4-Butyrolactone; Azides; Biological Transport; Diffusion; Ion Pumps; Pseudomonas aeruginosa

1999
Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis.
    Journal of bacteriology, 1999, Volume: 181, Issue:17

    Topics: 4-Butyrolactone; Acylation; Anti-Infective Agents, Local; Base Sequence; Cloning, Molecular; DNA, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Genes, Bacterial; Genome, Bacterial; Homoserine; Molecular Sequence Data; Oxidoreductases; Pseudomonas aeruginosa; Sequence Analysis, DNA; Triclosan

1999
Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila.
    Infection and immunity, 1999, Volume: 67, Issue:10

    Topics: 4-Butyrolactone; Aeromonas hydrophila; Exopeptidases; Metalloendopeptidases; Mutation; Peptide Hydrolases; Serine Endopeptidases; Virulence

1999
Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide.
    Molecular microbiology, 1999, Volume: 34, Issue:5

    Topics: 4-Butyrolactone; Biofilms; Catalase; Gene Expression Regulation, Bacterial; Homoserine; Hydrogen Peroxide; Methylphenazonium Methosulfate; Mutation; Oxidative Stress; Pseudomonas aeruginosa; Signal Transduction; Superoxide Dismutase; Transcription, Genetic

1999
New signal molecules on the quorum-sensing block.
    Trends in microbiology, 2000, Volume: 8, Issue:3

    Topics: 4-Butyrolactone; Bacterial Proteins; Diketopiperazines; DNA-Binding Proteins; Homoserine; Ligases; Piperazines; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Trans-Activators; Transcription Factors

2000
The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa.
    Journal of bacteriology, 2000, Volume: 182, Issue:10

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Ligases; Metalloendopeptidases; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Trans-Activators; Transcription Factors; Transcription, Genetic

2000
Dual control of hydrogen cyanide biosynthesis by the global activator GacA in Pseudomonas aeruginosa PAO1.
    FEMS microbiology letters, 2001, Jun-12, Volume: 200, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation, Bacterial; Hydrogen Cyanide; Multienzyme Complexes; Oxidoreductases; Oxidoreductases Acting on CH-NH2 Group Donors; Pseudomonas aeruginosa; RNA Processing, Post-Transcriptional

2001
The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo.
    Journal of bacteriology, 2002, Volume: 184, Issue:4

    Topics: 4-Butyrolactone; Animals; Cells, Cultured; Chemokines; Cyclooxygenase 2; Cytokines; Homoserine; Immunophenotyping; Isoenzymes; Keratinocytes; Lung; Mice; Mice, Inbred C57BL; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Pseudomonas aeruginosa; Skin; T-Lymphocytes; Th1 Cells; Virulence

2002
Detection of Pseudomonas aeruginosa cell-to-cell signals in lung tissue of cystic fibrosis patients.
    Microbial pathogenesis, 2002, Volume: 32, Issue:3

    Topics: 4-Butyrolactone; Adult; Bronchi; Cystic Fibrosis; Female; Homoserine; Humans; Lung; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Signal Transduction

2002
The regulation of biofilm development by quorum sensing in Aeromonas hydrophila.
    Environmental microbiology, 2002, Volume: 4, Issue:1

    Topics: 4-Butyrolactone; Aeromonas hydrophila; Bacterial Proteins; Biofilms; Blotting, Western; Culture Media; Ligases; Mutation; Time Factors

2002
The Pseudomonas aeruginosa rhlAB operon is not expressed during the logarithmic phase of growth even in the presence of its activator RhlR and the autoinducer N-butyryl-homoserine lactone.
    Journal of bacteriology, 2003, Volume: 185, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; Escherichia coli; Gene Expression Regulation, Bacterial; Glycolipids; Hexosyltransferases; Humans; Operon; Pseudomonas aeruginosa; Signal Transduction

2003
Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment.
    Journal of bacteriology, 2003, Volume: 185, Issue:7

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Cell Division; Culture Media; Gene Expression Regulation, Bacterial; Homeodomain Proteins; Homoserine; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Pseudomonas aeruginosa; Regulon; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction

2003
Negative control of quorum sensing by RpoN (sigma54) in Pseudomonas aeruginosa PAO1.
    Journal of bacteriology, 2003, Volume: 185, Issue:7

    Topics: 4-Butyrolactone; Bacterial Proteins; Cell Division; Cyclic AMP Receptor Protein; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Ligases; Mutagenesis, Site-Directed; Pseudomonas aeruginosa; Repressor Proteins; RNA Polymerase Sigma 54; Sigma Factor; Trans-Activators; Transcription Factors

2003
Library screening for synthetic agonists and antagonists of a Pseudomonas aeruginosa autoinducer.
    Chemistry & biology, 2003, Volume: 10, Issue:6

    Topics: 4-Butyrolactone; Aminophenols; Bacterial Proteins; Biofilms; DNA-Binding Proteins; Drug Design; Gene Library; Genes, Reporter; Genetic Techniques; Homoserine; Lactones; Molecular Structure; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Structure-Activity Relationship; Trans-Activators; Virulence Factors

2003
Biofilm formation by Pseudomonas aeruginosa: role of the C4-HSL cell-to-cell signal and inhibition by azithromycin.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:4

    Topics: 4-Butyrolactone; Azithromycin; Biofilms; Cell Communication; Humans; Pseudomonas aeruginosa; Signal Transduction

2003
The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR.
    Molecular microbiology, 2003, Volume: 50, Issue:1

    Topics: 4-Butyrolactone; Adaptation, Biological; Artificial Gene Fusion; Bacterial Proteins; Biofilms; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Reporter; Lectins; Mutagenesis, Insertional; Pseudomonas aeruginosa; Pyocyanine; Quinolones; Regulon; Sigma Factor; Signal Transduction; Trans-Activators; Virulence Factors

2003
Functional domains of the RhlR transcriptional regulator of Pseudomonas aeruginosa.
    Journal of bacteriology, 2003, Volume: 185, Issue:24

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation, Bacterial; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Pseudomonas aeruginosa; Serine Endopeptidases; Transcriptional Activation

2003
Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-09, Volume: 101, Issue:10

    Topics: 4-Butyrolactone; Animals; Cell Line; Cell Membrane; Cells, Cultured; CHO Cells; COS Cells; Cricetinae; Dogs; HeLa Cells; Homoserine; Humans; Immunity, Innate; Pseudomonas aeruginosa; Respiratory Mucosa; Signal Transduction; Virulence

2004
Bacterial quorum-sensing signals are inactivated by mammalian cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-23, Volume: 101, Issue:12

    Topics: 4-Butyrolactone; Epithelium; Homoserine; Humans; Pseudomonas aeruginosa; Respiratory System; Signal Transduction

2004
Enhancement of the mexAB-oprM efflux pump expression by a quorum-sensing autoinducer and its cancellation by a regulator, MexT, of the mexEF-oprN efflux pump operon in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:4

    Topics: 4-Butyrolactone; Bacterial Outer Membrane Proteins; Blotting, Western; Conjugation, Genetic; DNA, Recombinant; Gene Expression Regulation, Bacterial; Genetic Linkage; Lac Operon; Membrane Transport Proteins; Operon; Plasmids; Pseudomonas aeruginosa; Trans-Activators

2004
Pseudomonas aeruginosa autoinducer enters and functions in mammalian cells.
    Journal of bacteriology, 2004, Volume: 186, Issue:8

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Cell Nucleus; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Homoserine; Promoter Regions, Genetic; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Transcription Factors

2004
Expression of Pseudomonas aeruginosa exoS is controlled by quorum sensing and RpoS.
    Microbiology (Reading, England), 2004, Volume: 150, Issue:Pt 4

    Topics: 4-Butyrolactone; ADP Ribose Transferases; Bacterial Proteins; Bacterial Toxins; Biofilms; Culture Media; Gene Expression Regulation, Bacterial; Green Fluorescent Proteins; Humans; Ligases; Luminescent Proteins; Mutation; Plankton; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Sigma Factor; Transcription Factors

2004
A quorum-sensing autoinducer enhances the mexAB-oprM efflux-pump expression without the MexR-mediated regulation in Pseudomonas aeruginosa.
    Microbiology and immunology, 2004, Volume: 48, Issue:5

    Topics: 4-Butyrolactone; Bacterial Outer Membrane Proteins; Bacterial Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Membrane Transport Proteins; Pseudomonas aeruginosa; Repressor Proteins

2004
Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation.
    Organic & biomolecular chemistry, 2004, Nov-21, Volume: 2, Issue:22

    Topics: 4-Butyrolactone; Biochemistry; Cyclohexanones; Drug Evaluation, Preclinical; Fluorine; Homoserine; Hydrolysis; Isomerism; Ketones; Molecular Probes; Pseudomonas aeruginosa; Serratia; Structure-Activity Relationship

2004
The Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner.
    FEMS microbiology letters, 2004, Dec-01, Volume: 241, Issue:1

    Topics: 4-Butyrolactone; Aeromonas hydrophila; Bacterial Proteins; Binding Sites; Carrier Proteins; DNA; Gene Expression Regulation, Bacterial; Maltose-Binding Proteins; Promoter Regions, Genetic

2004
The two-component response regulator PprB modulates quorum-sensing signal production and global gene expression in Pseudomonas aeruginosa.
    Molecular microbiology, 2005, Volume: 56, Issue:5

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; DNA Transposable Elements; Gene Expression Regulation, Bacterial; Genes, Reporter; Homoserine; Ligases; Molecular Sequence Data; Movement; Mutagenesis, Insertional; Oligonucleotide Array Sequence Analysis; Pseudomonas aeruginosa; Sequence Alignment; Signal Transduction; Trans-Activators; Transcription Factors; Virulence Factors

2005
N-butanoyl-L-homoserine lactone (BHL) deficient Pseudomonas aeruginosa isolates from an intensive care unit.
    Microbiological research, 2005, Volume: 160, Issue:4

    Topics: 4-Butyrolactone; Acinetobacter baumannii; Agrobacterium tumefaciens; Chromobacterium; Escherichia coli; Humans; Inpatients; Intensive Care Units; Klebsiella pneumoniae; Pseudomonas aeruginosa; Pseudomonas Infections

2005
N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus.
    Infection and immunity, 2006, Volume: 74, Issue:2

    Topics: 4-Butyrolactone; Bacterial Proteins; Cell Membrane; Down-Regulation; Exotoxins; Gene Expression Regulation, Bacterial; Homoserine; Pseudomonas aeruginosa; Signal Transduction; Staphylococcus aureus; Trans-Activators; Virulence

2006
Influence of food system conditions on N-acyl-L-homoserine lactones production by Aeromonas spp.
    International journal of food microbiology, 2006, Dec-01, Volume: 112, Issue:3

    Topics: 4-Butyrolactone; Aeromonas; Carbohydrates; Consumer Product Safety; Culture Media; Food Contamination; Food Microbiology; Hydrogen-Ion Concentration; Phylogeny; Temperature; Time Factors

2006
[Negative regulation on PCA production is not correlated with positive regulation on BHL and HHL synthesis by gacA in Pseudomonas sp. M18].
    Wei sheng wu xue bao = Acta microbiologica Sinica, 2006, Volume: 46, Issue:3

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Bacterial Proteins; Chromatography, Thin Layer; Down-Regulation; Lac Operon; Ligases; Phenazines; Protein Biosynthesis; Pseudomonas; Up-Regulation

2006
Effect of temperature and glucose concentration on the N-butanoyl-L-homoserine lactone production by Aeromonas hydrophila.
    Food microbiology, 2006, Volume: 23, Issue:6

    Topics: 4-Butyrolactone; Aeromonas hydrophila; Colony Count, Microbial; Dose-Response Relationship, Drug; Food Contamination; Food Microbiology; Glucose; Kinetics; Temperature; Time Factors

2006
An rhl-like quorum-sensing system negatively regulates pyoluteorin production in Pseudomonas sp. M18.
    Microbiology (Reading, England), 2007, Volume: 153, Issue:Pt 1

    Topics: 4-Butyrolactone; Citrullus; Down-Regulation; Genes, Bacterial; Ligases; Molecular Sequence Data; Phenols; Plant Roots; Pseudomonas; Pyrroles; Quorum Sensing; Transcription Factors

2007
Acyl-homoserine lactones produced by Pantoea sp. isolated from the "maize white spot" foliar disease.
    Journal of agricultural and food chemistry, 2007, Feb-21, Volume: 55, Issue:4

    Topics: 4-Butyrolactone; Chromatography, Gas; Pantoea; Plant Diseases; Plant Leaves; Zea mays

2007
Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:10

    Topics: 4-Butyrolactone; Adaptation, Physiological; Anti-Bacterial Agents; beta-Galactosidase; Biofilms; Cyclopentanes; Genes, Reporter; Glycolipids; Homoserine; Pancreatic Elastase; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Virulence Factors

2007
The role of c-di-GMP signaling in an Aeromonas veronii biovar sobria strain.
    FEMS microbiology letters, 2007, Volume: 273, Issue:2

    Topics: 4-Butyrolactone; Aeromonas; Amoeba; Animals; Araceae; Bacterial Adhesion; Bacterial Proteins; Biofilms; Cyclic GMP; Protein Structure, Tertiary; Quorum Sensing; Salmonella typhimurium; Signal Transduction

2007
Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:18

    Topics: 4-Butyrolactone; Aliivibrio fischeri; Directed Molecular Evolution; Gene Expression Regulation, Bacterial; Repressor Proteins; Signal Transduction; Trans-Activators

2007
Characterization of N-butanoyl-L-homoserine lactone (C4-HSL) deficient clinical isolates of Pseudomonas aeruginosa.
    Microbial pathogenesis, 2008, Volume: 44, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; Humans; Ligases; Movement; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Transcription Factors; Virulence Factors

2008
Influence of quorum sensing and iron on twitching motility and biofilm formation in Pseudomonas aeruginosa.
    Journal of bacteriology, 2008, Volume: 190, Issue:2

    Topics: 4-Butyrolactone; Biofilms; Culture Media; Iron; Ligases; Locomotion; Mutagenesis, Insertional; Oligopeptides; Pseudomonas aeruginosa; Quorum Sensing; Transcription Factors

2008
Reactivity and reaction order in acylhomoserine lactone formation by Pseudomonas aeruginosa RhlI.
    Biochemistry, 2008, Mar-04, Volume: 47, Issue:9

    Topics: 4-Butyrolactone; Kinetics; Molecular Structure; Pseudomonas aeruginosa; S-Adenosylmethionine

2008
Quorum sensing signals are produced by Aeromonas salmonicida and quorum sensing inhibitors can reduce production of a potential virulence factor.
    Diseases of aquatic organisms, 2007, Dec-13, Volume: 78, Issue:2

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Aeromonas salmonicida; Animals; Fish Diseases; Fishes; Gene Expression Regulation, Bacterial; Gram-Negative Bacterial Infections; Peptide Hydrolases; Pigments, Biological; Quorum Sensing; Time Factors; Virulence Factors

2007
Pseudomonas aeruginosa quorum-sensing signal molecules induce IL-8 production by human corneal epithelial cells.
    Eye & contact lens, 2008, Volume: 34, Issue:3

    Topics: 4-Butyrolactone; Bacterial Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Homoserine; Humans; Interleukin-8; Pseudomonas aeruginosa; Quorum Sensing; Signal Transduction

2008
Quorum-sensing system affects gall development incited by Pantoea agglomerans pv. gypsophilae.
    Molecular plant-microbe interactions : MPMI, 2008, Volume: 21, Issue:8

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Caryophyllaceae; Cloning, Molecular; Gene Expression Regulation, Bacterial; Genes, Bacterial; Molecular Sequence Data; Pantoea; Plant Tumors; Quorum Sensing; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators; Transcription Factors

2008
[Expression of N-acyl-homoserine lactonase AiiA gene affects properties of rhizospheric strain Pseudomonas chlororaphis 449].
    Genetika, 2009, Volume: 45, Issue:1

    Topics: 4-Butyrolactone; Ascomycota; Carboxylic Ester Hydrolases; Gene Expression Regulation, Bacterial; Phenazines; Plasmids; Pseudomonas; Rhizoctonia

2009
Pseudomonas aeruginosa Las quorum sensing autoinducer suppresses growth and biofilm production in Legionella species.
    Microbiology (Reading, England), 2009, Volume: 155, Issue:Pt 6

    Topics: 4-Butyrolactone; Biofilms; Genes, Bacterial; Homoserine; Legionella pneumophila; Pseudomonas aeruginosa; Quorum Sensing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; Virulence; Virulence Factors; Water Microbiology

2009
The long-chain fatty acid sensor, PsrA, modulates the expression of rpoS and the type III secretion exsCEBA operon in Pseudomonas aeruginosa.
    Molecular microbiology, 2009, Volume: 73, Issue:1

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Mutagenesis, Site-Directed; Oleic Acid; Oligonucleotide Array Sequence Analysis; Operon; Protein Binding; Protein Structure, Tertiary; Pseudomonas aeruginosa; Quorum Sensing; Sigma Factor; Transcription Factors

2009
The distinct quorum sensing hierarchy of las and rhl in Pseudomonas sp. M18.
    Current microbiology, 2009, Volume: 59, Issue:6

    Topics: 4-Butyrolactone; Bacterial Proteins; Chromatography, Thin Layer; Gene Expression Regulation, Bacterial; Ligases; Phenazines; Pseudomonas; Pseudomonas aeruginosa; Quorum Sensing; Transcription Factors; Virulence Factors

2009
Identification of catechin as one of the flavonoids from Combretum albiflorum bark extract that reduces the production of quorum-sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1.
    Applied and environmental microbiology, 2010, Volume: 76, Issue:1

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Catechin; Chromatography, High Pressure Liquid; Combretum; Down-Regulation; Mass Spectrometry; Plant Bark; Plant Leaves; Pseudomonas aeruginosa; Virulence Factors

2010
Quorum sensing regulation in Aeromonas hydrophila.
    Journal of molecular biology, 2010, Mar-05, Volume: 396, Issue:4

    Topics: 4-Butyrolactone; Aeromonas hydrophila; Amino Acid Sequence; Bacterial Proteins; Base Sequence; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Green Fluorescent Proteins; Kinetics; Models, Biological; Molecular Sequence Data; Promoter Regions, Genetic; Quorum Sensing; Recombinant Proteins

2010
Biofilm-induced modifications in the proteome of Pseudomonas aeruginosa planktonic cells.
    Biochimica et biophysica acta, 2010, Volume: 1804, Issue:4

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; 4-Butyrolactone; Alcohol Oxidoreductases; Bacterial Proteins; Biofilms; Bioreactors; Gene Expression; Homoserine; Oxidative Stress; Plankton; Proteome; Pseudomonas aeruginosa; Quorum Sensing

2010
Growth inhibition of adherent Pseudomonas aeruginosa by an N-butanoyl-L-homoserine lactone analog.
    Canadian journal of microbiology, 2010, Volume: 56, Issue:4

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Biofilms; Drug Design; Drug Evaluation, Preclinical; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Structure-Activity Relationship; Virulence Factors

2010
Characterization of a phosphotriesterase-like lactonase from Sulfolobus solfataricus and its immobilization for disruption of quorum sensing.
    Applied and environmental microbiology, 2011, Volume: 77, Issue:4

    Topics: 4-Butyrolactone; Carboxylic Ester Hydrolases; Electrophoresis, Polyacrylamide Gel; Enzymes, Immobilized; Gene Expression; Lactones; Pancreatic Elastase; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Phosphoric Triester Hydrolases; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Sequence Analysis, DNA; Signal Transduction; Sulfolobus solfataricus; Virulence Factors

2011
The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1.
    Microbiology (Reading, England), 2011, Volume: 157, Issue:Pt 7

    Topics: 4-Butyrolactone; Bacterial Proteins; Combretum; Flavanones; Flavonoids; Gene Expression Regulation, Bacterial; Homoserine; Ligases; Pancreatic Elastase; Plant Preparations; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Sequence Deletion; Transcription Factors; Virulence Factors

2011
N-butyryl-homoserine lactone, a bacterial quorum-sensing signaling molecule, induces intracellular calcium elevation in Arabidopsis root cells.
    Biochemical and biophysical research communications, 2011, Oct-22, Volume: 414, Issue:2

    Topics: 4-Butyrolactone; Arabidopsis; Bacteria; Calcium; Plant Roots; Quorum Sensing; Signal Transduction

2011
Pseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulence.
    Journal of bacteriology, 2012, Volume: 194, Issue:17

    Topics: 4-Butyrolactone; Amino Acid Sequence; Bacterial Proteins; Biological Transport; Gene Expression Regulation, Bacterial; Membrane Proteins; Microbial Viability; Molecular Sequence Data; Mutation; Phenotype; Protein Sorting Signals; Pseudomonas aeruginosa; Quorum Sensing; Recombinant Proteins; Sequence Alignment; Serine Endopeptidases; Virulence Factors

2012
Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase.
    Biochemistry, 2013, Apr-02, Volume: 52, Issue:13

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Amidohydrolases; Catalytic Domain; Crystallography, X-Ray; Geobacillus; Manganese; Models, Molecular; Mutation; Quorum Sensing

2013
Phenazine antibiotic production and antifungal activity are regulated by multiple quorum-sensing systems in Pseudomonas chlororaphis subsp. aurantiaca StFRB508.
    Journal of bioscience and bioengineering, 2013, Volume: 116, Issue:5

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Antifungal Agents; Bacterial Proteins; Computer Simulation; Fusarium; Genome, Bacterial; Phenazines; Pseudomonas; Quorum Sensing

2013
Global regulatory networks control the hrp regulon of the gall-forming bacterium Pantoea agglomerans pv. gypsophilae.
    Molecular plant-microbe interactions : MPMI, 2013, Volume: 26, Issue:9

    Topics: 4-Butyrolactone; Bacterial Proteins; Caryophyllaceae; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Gene Regulatory Networks; Host-Pathogen Interactions; Models, Molecular; Mutation; Pantoea; Plant Leaves; Plant Tumors; Plasmids; Promoter Regions, Genetic; Protein Binding; Quorum Sensing; Regulon; RNA, Bacterial; Transcription Factors; Transcriptional Activation; Virulence

2013
Cis-2-dodecenoic acid signal modulates virulence of Pseudomonas aeruginosa through interference with quorum sensing systems and T3SS.
    BMC microbiology, 2013, Oct-18, Volume: 13

    Topics: 4-Butyrolactone; Animals; Antibiosis; Bacterial Secretion Systems; Biofilms; Burkholderia cenocepacia; Disease Models, Animal; Epithelial Cells; Fatty Acids, Monounsaturated; Gene Expression Profiling; HeLa Cells; Homoserine; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Quorum Sensing; Signal Transduction; Virulence; Virulence Factors; Zebrafish

2013
Role of Pseudomonas aeruginosa quorum sensing (QS) molecules on the viability and cytokine profile of human mesenchymal stem cells.
    Virulence, 2014, Feb-15, Volume: 5, Issue:2

    Topics: 4-Butyrolactone; 4-Quinolones; Apoptosis; Cell Survival; Cells, Cultured; Cytokines; Flow Cytometry; Homoserine; Humans; Mesenchymal Stem Cells; Pseudomonas aeruginosa; Quorum Sensing

2014
Interkingdom signaling and its consequences for human health.
    Virulence, 2014, Feb-15, Volume: 5, Issue:2

    Topics: 4-Butyrolactone; 4-Quinolones; Apoptosis; Cytokines; Homoserine; Humans; Mesenchymal Stem Cells; Pseudomonas aeruginosa; Quorum Sensing

2014
The Pseudomonas aeruginosa rhlG and rhlAB genes are inversely regulated and RhlG is not required for rhamnolipid synthesis.
    BMC microbiology, 2014, Jun-19, Volume: 14

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Glycolipids; Pseudomonas aeruginosa; Quorum Sensing; Sigma Factor; Transcription, Genetic

2014
Short chain N-acyl homoserine lactone production in tropical marine Vibrio sinaloensis strain T47.
    Sensors (Basel, Switzerland), 2014, Jul-18, Volume: 14, Issue:7

    Topics: 4-Butyrolactone; Biofilms; Quorum Sensing; RNA, Ribosomal, 16S; Vibrio

2014
Diverse Profiles of N-acyl Homoserine L-Lactones, Biofilm, Virulence Genes and Integrons in Food-Borne Aeromonas Isolates.
    Journal of food science, 2015, Volume: 80, Issue:8

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Aeromonas; Biofilms; Chromatography, Thin Layer; DNA Fragmentation; DNA, Bacterial; Food Contamination; Food Microbiology; Genes, Bacterial; India; Integrons; Quorum Sensing; Repressor Proteins; Trans-Activators; Virulence

2015
A sustainable method for effective regulation of anaerobic granular sludge: artificially increasing the concentration of signal molecules by cultivating a secreting strain.
    Bioresource technology, 2015, Volume: 196

    Topics: 4-Butyrolactone; Bacteria; Bioreactors; Culture Techniques; Homoserine; Lactones; Quorum Sensing; Sewage

2015
Promotion of acute-phase skin wound healing by Pseudomonas aeruginosa C
    International wound journal, 2016, Volume: 13, Issue:6

    Topics: 4-Butyrolactone; Acute Disease; Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Female; Homoserine; Immunohistochemistry; Neutrophils; Pseudomonas aeruginosa; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tumor Necrosis Factor-alpha; Wound Healing; Wounds and Injuries

2016
Rosmarinic acid is a homoserine lactone mimic produced by plants that activates a bacterial quorum-sensing regulator.
    Science signaling, 2016, Jan-05, Volume: 9, Issue:409

    Topics: 4-Butyrolactone; Bacterial Proteins; Cinnamates; Depsides; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Microbial Viability; Molecular Dynamics Simulation; Molecular Structure; Plants; Protein Binding; Protein Structure, Tertiary; Pseudomonas aeruginosa; Quorum Sensing; Rosmarinic Acid; Trans-Activators

2016
Quorum sensing activity of Citrobacter amalonaticus L8A, a bacterium isolated from dental plaque.
    Scientific reports, 2016, Feb-10, Volume: 6

    Topics: 4-Butyrolactone; Bacterial Proteins; Citrobacter; Dental Plaque; DNA, Bacterial; High-Throughput Nucleotide Sequencing; Homoserine; Humans; Lactones; Phylogeny; Quorum Sensing; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2016
Characterization of N-acyl homoserine lactones (AHLs) producing bacteria isolated from vacuum-packaged refrigerated turbot (Scophthalmus maximus) and possible influence of exogenous AHLs on bacterial phenotype.
    The Journal of general and applied microbiology, 2016, Volume: 62, Issue:2

    Topics: 4-Butyrolactone; Aeromonas; Animals; Biofilms; Biosensing Techniques; Flatfishes; Food Microbiology; Food Packaging; Gas Chromatography-Mass Spectrometry; Phenotype; Proteolysis; Quorum Sensing; Refrigeration; Seafood; Serratia; Vacuum

2016
Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
    Scientific reports, 2016, 07-01, Volume: 6

    Topics: 4-Butyrolactone; Acetylcysteine; Apoptosis; Aryldialkylphosphatase; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Homoserine; Humans; Microscopy, Electron, Transmission; Mitochondria; Mucin-2; Quorum Sensing

2016
Involvement of Acylated Homoserine Lactones (AHLs) of Aeromonas sobria in Spoilage of Refrigerated Turbot (Scophthalmus maximus L.).
    Sensors (Basel, Switzerland), 2016, Jul-13, Volume: 16, Issue:7

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Aeromonas; Animals; Flatfishes; Gas Chromatography-Mass Spectrometry; Homoserine; Lactones; Quorum Sensing; RNA, Ribosomal, 16S

2016
Potential Use of Dimethyl Sulfoxide in Treatment of Infections Caused by Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:12

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Biofilms; Dimethyl Sulfoxide; Disease Models, Animal; Female; Gene Expression Regulation, Bacterial; Glycolipids; Metalloproteases; Mice, Inbred C57BL; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Virulence Factors; Wound Infection

2016
Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems.
    Molecular cell, 2016, 12-15, Volume: 64, Issue:6

    Topics: 4-Butyrolactone; Bacterial Proteins; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Associated Proteins; CRISPR-Cas Systems; Endodeoxyribonucleases; Gene Expression Regulation, Bacterial; Quorum Sensing; Repressor Proteins; Serratia

2016
Inhibition of Pseudomonas aeruginosa quorum sensing by subinhibitory concentrations of curcumin with gentamicin and azithromycin.
    Journal of global antimicrobial resistance, 2017, Volume: 10

    Topics: 4-Butyrolactone; Azithromycin; Bacterial Proteins; Biofilms; Curcumin; Drug Combinations; Drug Synergism; Genes, Regulator; Gentamicins; Ligases; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quorum Sensing; RNA, Bacterial; Trans-Activators; Transcription Factors; Virulence Factors

2017
Pseudomonas aeruginosa quorum-sensing response in the absence of functional LasR and LasI proteins: the case of strain 148, a virulent dolphin isolate.
    FEMS microbiology letters, 2017, 07-03, Volume: 364, Issue:12

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Cyclic AMP Receptor Protein; Dolphins; Gene Expression Regulation, Bacterial; Glycolipids; Homoserine; Operon; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Trans-Activators; Transcription, Genetic; Virulence

2017
The human bitter taste receptor T2R38 is broadly tuned for bacterial compounds.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: 4-Butyrolactone; Antigens, Bacterial; Chronic Disease; Dimethyl Sulfoxide; HEK293 Cells; Humans; Immunity, Innate; Quorum Sensing; Receptors, G-Protein-Coupled; Rhinitis; Sinusitis; Staphylococcus aureus; Streptococcus pneumoniae

2017
Synthetic cells produce a quorum sensing chemical signal perceived by Pseudomonas aeruginosa.
    Chemical communications (Cambridge, England), 2018, Feb-22, Volume: 54, Issue:17

    Topics: 4-Butyrolactone; Artificial Cells; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Synthetic Biology

2018
Correlation Between Quorum Sensing Signal Molecules and Pseudomonas aeruginosa's Biofilm Development and Virulency.
    Current microbiology, 2018, Volume: 75, Issue:7

    Topics: 4-Butyrolactone; Biofilms; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing; Virulence; Virulence Factors

2018
Analysis of two quorum sensing-deficient isolates of Pseudomonas aeruginosa.
    Microbial pathogenesis, 2018, Volume: 119

    Topics: 4-Butyrolactone; Bacterial Proteins; Biofilms; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glycolipids; Kanamycin; Oligopeptides; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing; Sequence Analysis; Sequence Analysis, DNA; Sigma Factor; Tobramycin; Virulence Factors

2018
Stochastic Turing patterns in a synthetic bacterial population.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 06-26, Volume: 115, Issue:26

    Topics: 4-Butyrolactone; Bacterial Proteins; Binding, Competitive; Computer Simulation; Diffusion; Gene Expression Regulation, Bacterial; Genes, Reporter; Homoserine; Isopropyl Thiogalactoside; Ligases; Models, Biological; Morphogenesis; Promoter Regions, Genetic; Pseudomonas aeruginosa; Quorum Sensing; Recombinant Proteins; Stochastic Processes; Trans-Activators; Transcription Factors

2018
Identification of ligand binding activity and DNA recognition by RhlR protein from opportunistic pathogen Pseudomonas aeruginosa-a molecular dynamic simulation approach.
    Journal of molecular recognition : JMR, 2018, Volume: 31, Issue:12

    Topics: 4-Butyrolactone; Bacterial Proteins; Binding Sites; DNA, Bacterial; Gene Expression Regulation, Bacterial; Ligands; Models, Molecular; Molecular Dynamics Simulation; Promoter Regions, Genetic; Protein Binding; Protein Multimerization; Pseudomonas aeruginosa; Transcription, Genetic

2018
Pseudomonas aeruginosa quorum sensing molecule N-3-oxo-dodecanoyl-l-homoserine lactone activates human platelets through intracellular calcium-mediated ROS generation.
    International journal of medical microbiology : IJMM, 2018, Volume: 308, Issue:7

    Topics: 4-Butyrolactone; Blood Platelets; Calcium; Homoserine; Humans; Inositol 1,4,5-Trisphosphate Receptors; Platelet Activation; Pseudomonas aeruginosa; Quorum Sensing; Reactive Oxygen Species; Type C Phospholipases

2018
Structure-Function Analyses of the N-Butanoyl l-Homoserine Lactone Quorum-Sensing Signal Define Features Critical to Activity in RhlR.
    ACS chemical biology, 2018, 09-21, Volume: 13, Issue:9

    Topics: 4-Butyrolactone; Bacterial Proteins; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Small Molecule Libraries

2018
Characterization of quorum sensing genes and N-acyl homoserine lactones in Citrobacter amalonaticus strain YG6.
    Gene, 2019, Feb-05, Volume: 684

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Bacterial Proteins; Base Sequence; Carboxylic Ester Hydrolases; Citrobacter; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Homoserine; Lactones; Quorum Sensing

2019
Preliminary study testing the effects of tea and coffee on sludge characteristics and N-butyryl-l-homoserine lactone in an MBR system.
    Environmental technology, 2020, Volume: 41, Issue:16

    Topics: 4-Butyrolactone; Bioreactors; Coffee; Membranes, Artificial; Sewage; Tea

2020
C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: 4-Butyrolactone; Aptamers, Nucleotide; Bacterial Proteins; Biofilms; Drug Design; Models, Molecular; Nucleic Acid Conformation; Protein Binding; Pseudomonas aeruginosa; Quorum Sensing; Structure-Activity Relationship

2019
Characterization of LuxI/LuxR and their regulation involved in biofilm formation and stress resistance in fish spoilers Pseudomonas fluorescens.
    International journal of food microbiology, 2019, May-16, Volume: 297

    Topics: 4-Butyrolactone; Animals; Bacterial Proteins; Biofilms; Fishes; Gene Expression Regulation, Bacterial; Pseudomonas fluorescens; Repressor Proteins; Seafood; Sequence Deletion; Stress, Physiological; Trans-Activators; Transcription Factors

2019
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    mBio, 2019, 10-08, Volume: 10, Issue:5

    Topics: 4-Butyrolactone; 5' Untranslated Regions; Bacterial Proteins; Gene Expression Regulation, Bacterial; Ligases; Pseudomonas aeruginosa; Quorum Sensing; RNA, Small Untranslated; Transcription Factors

2019
    Journal of medical microbiology, 2020, Volume: 69, Issue:6

    Topics: 4-Butyrolactone; Bacterial Proteins; Biofilms; Equipment Contamination; Fimbriae, Bacterial; Flagella; Intubation, Intratracheal; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Quorum Sensing

2020
Tarragon essential oil as a source of bioactive compounds with anti-quorum sensing and anti-proteolytic activity against Pseudomonas spp. isolated from fish - in vitro, in silico and in situ approaches.
    International journal of food microbiology, 2020, Oct-16, Volume: 331

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Artemisia; Computer Simulation; Fishes; Homoserine; Oils, Volatile; Proteolysis; Pseudomonas; Quorum Sensing

2020
An innovative role for luteolin as a natural quorum sensing inhibitor in Pseudomonas aeruginosa.
    Life sciences, 2021, Jun-01, Volume: 274

    Topics: 4-Butyrolactone; Bacterial Proteins; Biofilms; Gene Expression Regulation, Bacterial; Homoserine; Humans; Luteolin; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Trans-Activators; Virulence Factors

2021
The antimicrobial effect of quorum sensing autoinducers of Pseudomonas aeruginosa, C12-HSL and C4-HSL, against MDR Staphylococcus aureus isolates.
    Comparative immunology, microbiology and infectious diseases, 2022, Volume: 81

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; HeLa Cells; Humans; Pseudomonas aeruginosa; Quorum Sensing; Staphylococcus aureus

2022
New insights into exogenous N-acyl-homoserine lactone manipulation in biological nitrogen removal system against ZnO nanoparticle shock.
    Bioresource technology, 2023, Volume: 370

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Denitrification; Extracellular Polymeric Substance Matrix; Quorum Sensing; Zinc Oxide

2023
Simultaneous regulation of biocathodic γ-HCH dechlorination and CH
    Environmental pollution (Barking, Essex : 1987), 2023, Oct-15, Volume: 335

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Biofilms; Hexachlorocyclohexane; Quorum Sensing

2023